IN2014CN02578A - - Google Patents

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Publication number
IN2014CN02578A
IN2014CN02578A IN2578CHN2014A IN2014CN02578A IN 2014CN02578 A IN2014CN02578 A IN 2014CN02578A IN 2578CHN2014 A IN2578CHN2014 A IN 2578CHN2014A IN 2014CN02578 A IN2014CN02578 A IN 2014CN02578A
Authority
IN
India
Prior art keywords
medicine
medical device
intimal
proliferation
suppressing proliferation
Prior art date
Application number
Inventor
Dadong Zhang
Xu Cai
Chengyun Yue
Junfei Li
Yan Hu
Peng Huang
Zhirong Tang
Qiyi Luo
Original Assignee
Shanghai Microport Medical Group Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Microport Medical Group Co Ltd filed Critical Shanghai Microport Medical Group Co Ltd
Publication of IN2014CN02578A publication Critical patent/IN2014CN02578A/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/146—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A61F2250/0068—Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/02—Methods for coating medical devices

Abstract

An interventional medical device and a manufacturing method thereof. The interventional medical device comprises: a support body (1) a surface of the support body (1) being provided with a medicine releasing structure (3) and medicine in the medicine releasing structure (3) being medicine for suppressing proliferation of adventitial fibroblasts and a medicine for suppressing proliferation of intimal and/or smooth muscle cells. In use after the interventional medical device is implanted in a human body the medicine for suppressing proliferation of adventitial fibroblasts carried thereon can promote the compensatory expansion of the vessel and the medicine for suppressing proliferation of intimal and/or smooth muscle cells carried thereon can suppress intimal proliferation of the vessel. The combination of the two kinds of medicine greatly reduces the occurrence rate of in stent restenosis.
IN2578CHN2014 2011-09-29 2012-01-16 IN2014CN02578A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2011102953249A CN102499798A (en) 2011-09-29 2011-09-29 Interventional medical device and preparation method thereof
PCT/CN2012/070400 WO2013044603A1 (en) 2011-09-29 2012-01-16 Interventional medical device and manufacturing method thereof

Publications (1)

Publication Number Publication Date
IN2014CN02578A true IN2014CN02578A (en) 2015-08-07

Family

ID=46211977

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2578CHN2014 IN2014CN02578A (en) 2011-09-29 2012-01-16

Country Status (7)

Country Link
US (2) US20140248327A1 (en)
EP (1) EP2762110A4 (en)
JP (1) JP2014530058A (en)
CN (1) CN102499798A (en)
BR (1) BR112014007580A2 (en)
IN (1) IN2014CN02578A (en)
WO (1) WO2013044603A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102397119A (en) * 2011-09-29 2012-04-04 微创医疗器械(上海)有限公司 Interventional medical appliance and manufacturing method thereof
US10232077B2 (en) * 2014-10-06 2019-03-19 Gatt Technologies B.V. Tissue-adhesive porous haemostatic product
DE112014007192T5 (en) * 2014-12-25 2017-08-24 Olympus Corporation Osteosynthetic implant and manufacturing method therefor
CN105816921A (en) * 2016-04-20 2016-08-03 山东百多安医用材料改性工程技术中心 Bionic vascular stent and preparation method thereof
CN106512188A (en) * 2016-12-13 2017-03-22 天津飞捷科技有限公司 Mechanical and electrical integrated targeted drug release intervention medical instrument and preparation method thereof
CN109602523B (en) * 2019-01-03 2024-02-09 科塞尔医疗科技（苏州）有限公司 Recoverable medicine support
CN110283296B (en) * 2019-06-20 2020-07-31 中国科学院长春应用化学研究所 Difunctional polyurethane and preparation method and application thereof

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6273913B1 (en) * 1997-04-18 2001-08-14 Cordis Corporation Modified stent useful for delivery of drugs along stent strut
US6908624B2 (en) * 1999-12-23 2005-06-21 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
CN1568166A (en) * 2001-10-15 2005-01-19 荷姆泰克股份有限公司 Coating of stents for preventing restenosis
EP1308179A1 (en) * 2001-10-30 2003-05-07 Boehringer Ingelheim Pharma GmbH & Co.KG Improved endoprosthetic device
US20050019404A1 (en) * 2003-06-30 2005-01-27 Hsing-Wen Sung Drug-eluting biodegradable stent
JP4588986B2 (en) * 2002-08-20 2010-12-01 テルモ株式会社 Implantable medical device
AU2004216541A1 (en) 2003-02-28 2004-09-10 Howard Florey Institute Of Experimental Physiology And Medicine Therapeutic compositions
US7488343B2 (en) * 2003-09-16 2009-02-10 Boston Scientific Scimed, Inc. Medical devices
US20070219613A1 (en) 2003-10-06 2007-09-20 Xtent, Inc. Apparatus and methods for interlocking stent segments
US8003122B2 (en) 2004-03-31 2011-08-23 Cordis Corporation Device for local and/or regional delivery employing liquid formulations of therapeutic agents
US20050266040A1 (en) * 2004-05-28 2005-12-01 Brent Gerberding Medical devices composed of porous metallic materials for delivering biologically active materials
EA016906B1 (en) * 2004-08-13 2012-08-30 Рутгерс, Дзе Стейт Юниверсити Radiopaque polymeric stents
US20060199876A1 (en) * 2005-03-04 2006-09-07 The University Of British Columbia Bioceramic composite coatings and process for making same
US20070224235A1 (en) * 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US8187620B2 (en) * 2006-03-27 2012-05-29 Boston Scientific Scimed, Inc. Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents
US20070292470A1 (en) * 2006-06-15 2007-12-20 Medtronic Vascular, Inc. Implantable Medical Devices and Methods for Making the Same
NZ574597A (en) * 2006-07-03 2011-11-25 Hemoteq Ag Stent coated with a biodegradable polymer and rapamycin
CN100493627C (en) * 2006-10-20 2009-06-03 东南大学 Coronary artery medicinal-coating stent
CN101199873B (en) * 2006-12-14 2013-06-19 乐普（北京）医疗器械股份有限公司 Medicament elution instrument nanometer class colon washer machineole drug releasing structure and preparing method thereof
US8187255B2 (en) * 2007-02-02 2012-05-29 Boston Scientific Scimed, Inc. Medical devices having nanoporous coatings for controlled therapeutic agent delivery
CA2680229A1 (en) * 2007-03-09 2008-09-18 Jay S. Yadav Bioabsorbable coatings for medical devices
CN101318032B (en) 2007-06-06 2012-11-21 李京倖 Small-diameter tissue engineering artificial blood vessel and preparation method thereof
US20090018646A1 (en) * 2007-07-10 2009-01-15 Zhao Jonathon Z Coating Employing an Anti-Thrombotic Conjugate
CN101406713B (en) 2007-10-12 2012-09-19 微创医疗器械(上海)有限公司 Artificial blood vessel bracket and preparation method thereof
CN101945621B (en) * 2007-12-18 2014-06-18 因特尔赛克特耳鼻喉公司 Self-expanding devices and methods therefor
KR100947094B1 (en) * 2008-01-02 2010-03-10 주식회사 디오 Stent for medical use and manufacturing method thereof
JP5530361B2 (en) 2008-09-17 2014-06-25 テルモ株式会社 Stent
US20100280600A1 (en) * 2009-04-30 2010-11-04 Vipul Bhupendra Dave Dual drug stent
CN101879102B (en) * 2009-05-07 2014-07-09 上海微创医疗器械（集团）有限公司 Groove carrying-type coating decomposable drug eluting stent
CN102397119A (en) 2011-09-29 2012-04-04 微创医疗器械(上海)有限公司 Interventional medical appliance and manufacturing method thereof

Also Published As

Publication number Publication date
US20150209485A1 (en) 2015-07-30
BR112014007580A2 (en) 2017-04-11
EP2762110A4 (en) 2015-05-06
WO2013044603A1 (en) 2013-04-04
US20140248327A1 (en) 2014-09-04
JP2014530058A (en) 2014-11-17
EP2762110A1 (en) 2014-08-06
CN102499798A (en) 2012-06-20
US9433709B2 (en) 2016-09-06

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