IN2013CN00459A - - Google Patents
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- Publication number
- IN2013CN00459A IN2013CN00459A IN459CHN2013A IN2013CN00459A IN 2013CN00459 A IN2013CN00459 A IN 2013CN00459A IN 459CHN2013 A IN459CHN2013 A IN 459CHN2013A IN 2013CN00459 A IN2013CN00459 A IN 2013CN00459A
- Authority
- IN
- India
- Prior art keywords
- dicarboxylic acid
- methods
- relates
- present
- dicarboxylic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
- C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/38—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The present invention relates to methods of producing C4 dicarboxylic acids such as malic acid comprising: (a) cultivating a host cell comprising a polynucleotide encoding a C4 dicarboxylic acid transporter; and (b) recovering the C4 dicarboxylic acid. The present invention also relates to methods for increasing C4 dicarboxylic acid production as well as host cells comprising the polynucleotides.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35700710P | 2010-06-21 | 2010-06-21 | |
PCT/US2011/041301 WO2011163270A1 (en) | 2010-06-21 | 2011-06-21 | Methods for improved c4-dicarboxylic acid production in filamentous fungi |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2013CN00459A true IN2013CN00459A (en) | 2015-07-03 |
Family
ID=44504321
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN459CHN2013 IN2013CN00459A (en) | 2010-06-21 | 2011-06-21 |
Country Status (6)
Country | Link |
---|---|
US (2) | US8497103B2 (en) |
EP (1) | EP2582829B1 (en) |
CN (1) | CN102947458B (en) |
BR (1) | BR112012028031A2 (en) |
IN (1) | IN2013CN00459A (en) |
WO (1) | WO2011163270A1 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2012002532A (en) * | 2009-09-01 | 2012-04-11 | Novozymes Inc | Methods for improving malic acid production in filamentous fungi. |
WO2014142647A1 (en) * | 2013-03-14 | 2014-09-18 | Wageningen Universiteit | Fungals strains with improved citric acid and itaconic acid production |
EP3161142A4 (en) * | 2014-06-26 | 2018-05-16 | Lygos, Inc. | Recombinant host cells for the production of malonate |
CN106148209B (en) * | 2015-03-23 | 2020-11-20 | 中国科学院天津工业生物技术研究所 | Novel binary organic acid producing strain and preparation and application thereof |
BR112017017262A2 (en) * | 2015-02-15 | 2018-04-17 | Tianjin Inst Ind Biotechnology Cas | strain of dibasic organic acid production, preparation and application thereof |
CN106148208B (en) * | 2015-03-23 | 2020-12-18 | 中国科学院天津工业生物技术研究所 | Novel binary organic acid producing strain and preparation and application thereof |
JP6637712B2 (en) * | 2015-10-13 | 2020-01-29 | 花王株式会社 | Method for producing C4 dicarboxylic acid |
CN105754963A (en) * | 2016-05-19 | 2016-07-13 | 江南大学 | Method for improving yield of fumaric acid |
US20190194700A1 (en) * | 2016-09-15 | 2019-06-27 | Kao Corporation | Mutant Filamentous Fungus and Method for Producing C4 Dicarboxylic Acid Using Same |
CN114806899B (en) * | 2022-04-14 | 2024-04-02 | 王玮 | Trichoderma reesei engineering bacteria for producing L-malic acid and application thereof |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1047002A (en) | 1911-04-03 | 1912-12-10 | James S Diehl | Scissors. |
US3063910A (en) | 1960-02-03 | 1962-11-13 | Kyowa Hakko Kogyo Kk | Method of producing l-malic acid by fermentation |
DK122686D0 (en) | 1986-03-17 | 1986-03-17 | Novo Industri As | PREPARATION OF PROTEINS |
US5536661A (en) | 1987-03-10 | 1996-07-16 | Novo Nordisk A/S | Process for the production of protein products in aspergillus |
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
IL99552A0 (en) | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof |
DE4343591A1 (en) | 1993-12-21 | 1995-06-22 | Evotec Biosystems Gmbh | Process for the evolutionary design and synthesis of functional polymers based on shape elements and shape codes |
US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
JP3649338B2 (en) | 1994-06-03 | 2005-05-18 | ノボザイムス バイオテック,インコーポレイティド | Purified Myserioftra laccase and nucleic acid encoding it |
EP1559776A3 (en) | 1994-06-30 | 2006-01-11 | Novozymes Biotech, Inc. | Non-toxic, non-toxigenic, non-pathogenic Fusarium expression system and promoters and terminators for use therein |
US5766439A (en) | 1996-10-10 | 1998-06-16 | A. E. Staley Manufacturing Co. | Production and recovery of organic acids |
US7504490B1 (en) * | 1998-10-16 | 2009-03-17 | Oscient Pharmaceuticals Corporation | Nucleic acid and amino acid sequences relating to Apergillus fumigatus for diagnostics and therapeutics |
DK1124949T3 (en) | 1998-10-26 | 2006-11-06 | Novozymes As | Construction and screening of a DNA library of interest in filamentous fungal cells |
CN100482801C (en) | 1999-03-22 | 2009-04-29 | 诺沃奇梅兹有限公司 | Promoters for expressing genes in fungal cell |
US7601865B2 (en) | 2004-01-29 | 2009-10-13 | Zeachem, Inc. | Recovery of organic acids |
US20080090273A1 (en) * | 2005-11-21 | 2008-04-17 | Aaron Adriaan Winkler | Malic Acid Production in Recombinant Yeast |
EP2155885A4 (en) | 2007-05-18 | 2010-12-01 | Microbia Prec Engineering Inc | Malic acid production in recombinant yeast |
EP2158323A4 (en) | 2007-05-18 | 2011-06-22 | Microbia Prec Engineering Inc | Organic acid production by fungal cells |
BRPI0819273B8 (en) | 2007-11-20 | 2022-07-19 | Dsm Ip Assets Bv | RECOMBINANT EUKARYOTIC MICROBIAL CELL AND PROCESS FOR THE PREPARATION OF A DICARBOXYLIC ACID |
EP2304039B1 (en) | 2008-06-17 | 2019-08-21 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate |
US9012187B2 (en) | 2008-07-08 | 2015-04-21 | Dsm Ip Assets B.V. | Dicarboxylic acid production by fermentation at low pH |
WO2010111344A2 (en) | 2009-03-24 | 2010-09-30 | Microbia, Inc. | Methods and microorganisms for production of c4-dicarboxylic acids |
JP2012223091A (en) | 2009-08-25 | 2012-11-15 | Ajinomoto Co Inc | Method for producing l-amino acid |
MX2012002532A (en) | 2009-09-01 | 2012-04-11 | Novozymes Inc | Methods for improving malic acid production in filamentous fungi. |
WO2011066304A2 (en) | 2009-11-25 | 2011-06-03 | Codexis, Inc. | Engineered beta-class carbonic anhydrase polypeptides and uses thereof |
-
2011
- 2011-06-21 EP EP11728507.2A patent/EP2582829B1/en not_active Not-in-force
- 2011-06-21 IN IN459CHN2013 patent/IN2013CN00459A/en unknown
- 2011-06-21 CN CN201180030913.2A patent/CN102947458B/en not_active Expired - Fee Related
- 2011-06-21 BR BR112012028031A patent/BR112012028031A2/en not_active IP Right Cessation
- 2011-06-21 US US13/165,719 patent/US8497103B2/en not_active Expired - Fee Related
- 2011-06-21 WO PCT/US2011/041301 patent/WO2011163270A1/en active Application Filing
-
2013
- 2013-06-25 US US13/926,421 patent/US20130288321A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20130288321A1 (en) | 2013-10-31 |
EP2582829B1 (en) | 2016-11-30 |
WO2011163270A1 (en) | 2011-12-29 |
CN102947458B (en) | 2016-05-04 |
BR112012028031A2 (en) | 2019-09-24 |
US20110312046A1 (en) | 2011-12-22 |
US8497103B2 (en) | 2013-07-30 |
CN102947458A (en) | 2013-02-27 |
EP2582829A1 (en) | 2013-04-24 |
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