IN2012MU01383A - - Google Patents

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Publication number
IN2012MU01383A
IN2012MU01383A IN1383MU2012A IN2012MU01383A IN 2012MU01383 A IN2012MU01383 A IN 2012MU01383A IN 1383MU2012 A IN1383MU2012 A IN 1383MU2012A IN 2012MU01383 A IN2012MU01383 A IN 2012MU01383A
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IN
India
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed filed Critical
Priority to IN1383MU2012 priority Critical patent/IN2012MU01383A/en
Priority to PCT/IN2013/000296 priority patent/WO2013179300A2/en
Publication of IN2012MU01383A publication Critical patent/IN2012MU01383A/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
IN1383MU2012 2012-05-04 2013-05-03 IN2012MU01383A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IN1383MU2012 IN2012MU01383A (en) 2012-05-04 2013-05-03
PCT/IN2013/000296 WO2013179300A2 (en) 2012-05-04 2013-05-03 A process for the preparation of vildagliptin and its intermediate thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN1383MU2012 IN2012MU01383A (en) 2012-05-04 2013-05-03

Publications (1)

Publication Number Publication Date
IN2012MU01383A true IN2012MU01383A (en) 2014-02-28

Family

ID=49213010

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1383MU2012 IN2012MU01383A (en) 2012-05-04 2013-05-03

Country Status (2)

Country Link
IN (1) IN2012MU01383A (en)
WO (1) WO2013179300A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021116897A1 (en) * 2019-12-10 2021-06-17 Optimus Drugs (P) Ltd Process for the preparation of vildagliptin

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015092806A1 (en) * 2013-12-18 2015-06-25 Harman Finochem Limited An advanced and cost-effective process for preparing highly pure vildagliptin
CN103724248B (en) * 2014-01-16 2018-07-27 万全万特制药江苏有限公司 The preparation method of vildagliptin process contaminants
CN103804267B (en) * 2014-02-21 2016-06-08 张家港威胜生物医药有限公司 A kind of synthesis technique of vildagliptin
CN103896819B (en) * 2014-03-25 2016-02-24 宁波美诺华药业股份有限公司 A kind of preparation method of (S)-1-chloracetyl tetramethyleneimine-2-methane amide
WO2015145467A1 (en) * 2014-03-28 2015-10-01 Laurus Labs Private Limited An improved process for preparing vildagliptin
CN103992257B (en) * 2014-05-16 2016-03-30 苏州天马精细化学品股份有限公司 A kind of purification process of Vildagliptin crude product
CN104016895A (en) * 2014-06-24 2014-09-03 万特制药(海南)有限公司 Preparation method of vildagliptin oxidization impurities
CN105439873A (en) * 2014-08-20 2016-03-30 天津药物研究院 3-hydroxy-1-amantadine preparation method
CN104311467B (en) * 2014-09-11 2017-07-21 上海医药集团青岛国风药业股份有限公司 Pipe reaction continuously prepares the method and device of vildagliptin
CN104262227B (en) * 2014-09-16 2018-09-18 东北制药集团股份有限公司 A method of preparing (S) -1- (2- chloracetyls) pyrrolidines -2- formonitrile HCNs
CN104945299B (en) * 2015-05-28 2017-03-15 烟台万润药业有限公司 A kind of high-efficiency synthesis method of vildagliptin
CN105037234B (en) * 2015-07-30 2017-10-24 上海医药集团青岛国风药业股份有限公司 A kind of preparation method of vildagliptin degradation impurity
CN105085360A (en) * 2015-09-10 2015-11-25 南京理工大学 Preparation method of high-purity vildagliptin
CN105193752B (en) * 2015-10-27 2018-03-30 石家庄康贺威药业有限公司 A kind of vildagliptin tablet and preparation method thereof
CN106117104B (en) * 2016-06-17 2018-11-20 东北制药集团股份有限公司 A kind of preparation method of vildagliptin
CN106699627A (en) * 2016-12-29 2017-05-24 青岛黄海制药有限责任公司 Method for preparing 1-(2-chloracetyl)-2-(S)-cyano pyrrolidine through multiphase compound non-continuous production process
CN107325010A (en) * 2017-08-14 2017-11-07 四川众邦制药有限公司 The safe preparation method and device of a kind of adamantanol
CN110117122B (en) * 2019-06-17 2022-03-01 卢玉献 Hydroxypropyl methyl production wastewater treatment method
WO2022003405A1 (en) 2020-07-03 2022-01-06 Savoi Guilherme One-pot process to obtain a pyrrolidine-2-carbonitrile intermediate compound and industrial scale telescopic process to prepare (2s)-1-[n-(3-hydroxyadamantan-1-yl)glycyl]-2-pyrrolidinecarbonitrile (vildagliptin) using same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO5150173A1 (en) 1998-12-10 2002-04-29 Novartis Ag COMPOUNDS N- (REPLACED GLYCLE) -2-DIPEPTIDYL-IV PEPTIDASE INHIBITING CYANOPIRROLIDINS (DPP-IV) WHICH ARE EFFECTIVE IN THE TREATMENT OF CONDITIONS MEDIATED BY DPP-IV INHIBITION
PE20050021A1 (en) 2003-04-16 2005-03-15 Novartis Ag PROCEDURE FOR THE PREPARATION OF N-SUBSTITUTED 2-CYANOPYRROLIDINE
GT200600008A (en) 2005-01-18 2006-08-09 FORMULATION OF DIRECT COMPRESSION AND PROCESS
WO2008084383A2 (en) * 2007-01-10 2008-07-17 Medichem, S.A. Process for preparing vildagliptin
PL2247602T3 (en) * 2007-11-30 2013-08-30 Novartis Ag Adamantyl o-glucuronide derivatives as inhibitors of dipeptidyl peptidase iv for the treatment of diabetes
CZ2008512A3 (en) * 2008-08-26 2010-03-10 Zentiva, A. S Process for preparing extremely pure vildagliptin
WO2011101861A1 (en) * 2010-01-29 2011-08-25 Msn Laboratories Limited Process for preparation of dpp-iv inhibitors

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021116897A1 (en) * 2019-12-10 2021-06-17 Optimus Drugs (P) Ltd Process for the preparation of vildagliptin

Also Published As

Publication number Publication date
WO2013179300A2 (en) 2013-12-05
WO2013179300A3 (en) 2014-08-28

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