IN2012DN03846A - - Google Patents
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- IN2012DN03846A IN2012DN03846A IN3846DEN2012A IN2012DN03846A IN 2012DN03846 A IN2012DN03846 A IN 2012DN03846A IN 3846DEN2012 A IN3846DEN2012 A IN 3846DEN2012A IN 2012DN03846 A IN2012DN03846 A IN 2012DN03846A
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07C211/45—Monoamines
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- C07C211/50—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring having at least two amino groups bound to the carbon skeleton with at least two amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
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- C07C233/11—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
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- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
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Abstract
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: Formula I wherein R1, R2, R3, Ra, and Y are defined herein.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25641209P | 2009-10-30 | 2009-10-30 | |
PCT/US2010/054497 WO2011053706A1 (en) | 2009-10-30 | 2010-10-28 | 4-substituted-2-phenoxy-phenylamine delta opioid receptor modulators |
Publications (1)
Publication Number | Publication Date |
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IN2012DN03846A true IN2012DN03846A (en) | 2015-08-28 |
Family
ID=43332569
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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IN3846DEN2012 IN2012DN03846A (en) | 2009-10-30 | 2010-10-28 |
Country Status (10)
Country | Link |
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US (1) | US8846655B2 (en) |
EP (1) | EP2493852B1 (en) |
JP (1) | JP5781527B2 (en) |
CN (1) | CN102741226B (en) |
AU (1) | AU2010313402B2 (en) |
BR (1) | BR112012011443A2 (en) |
CA (1) | CA2779108C (en) |
IN (1) | IN2012DN03846A (en) |
RU (1) | RU2553453C2 (en) |
WO (1) | WO2011053706A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011053701A1 (en) * | 2009-10-30 | 2011-05-05 | Janssen Pharmaceutica Nv | Phenoxy-substituted pyrimidines as opioid receptor modulators |
CA2779083C (en) * | 2009-10-30 | 2017-07-04 | Peter J. Connolly | Pyrazines as delta opioid receptor modulators |
RU2686101C2 (en) | 2013-03-12 | 2019-04-24 | Селтакссис, Инк. | Methods of inhibiting leucotreen-a4-hydrolases |
BR112015022226A2 (en) * | 2013-03-14 | 2017-07-18 | Celtaxsys Inc | leukotriene a4 hydrolase inhibitors |
MX2015011678A (en) | 2013-03-14 | 2016-07-08 | Celtaxsys Inc | Inhibitors of leukotriene a4 hydrolase. |
CN103788019B (en) * | 2014-01-22 | 2015-10-07 | 苏州明锐医药科技有限公司 | The fertile preparation method for Xi Ting |
EP3307725A1 (en) * | 2015-06-11 | 2018-04-18 | Basilea Pharmaceutica International AG | Efflux-pump inhibitors and therapeutic uses thereof |
US10898484B2 (en) | 2018-05-31 | 2021-01-26 | Celltaxis, Llc | Method of reducing pulmonary exacerbations in respiratory disease patients |
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PT86407B (en) * | 1986-12-31 | 1990-11-20 | Fujisawa Pharmaceutical Co | METHOD FOR PREPARING NEW ALCANO-SULFONANILIDA DERIVATIVES, AND OF PHARMACEUTICAL COMPOSITIONS UNDERSTANDING THE SAME |
JP4302207B2 (en) * | 1997-08-04 | 2009-07-22 | 大正製薬株式会社 | Aryloxyaniline derivatives |
AU2009799A (en) * | 1997-12-24 | 1999-07-19 | Ortho-Mcneil Pharmaceutical, Inc. | 4-(aryl(piperidin-4-yl)) aminobenzamides which bind to the delta-opioid receptor |
UA81749C2 (en) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Derivated of phenylpiperazine as serotonin reuptake inhibitorS |
ATE432279T1 (en) * | 2004-12-22 | 2009-06-15 | Janssen Pharmaceutica Nv | TRICYCLIC DELTA OPIOID MODULATORS |
JP2008526878A (en) * | 2005-01-06 | 2008-07-24 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Tricyclic δ-opioid regulator |
JP2010502688A (en) * | 2006-09-08 | 2010-01-28 | ファイザー・プロダクツ・インク | Diaryl ether derivatives and uses thereof |
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AU2010313402A1 (en) | 2012-05-24 |
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WO2011053706A1 (en) | 2011-05-05 |
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BR112012011443A2 (en) | 2020-09-08 |
CA2779108A1 (en) | 2011-05-05 |
AU2010313402B2 (en) | 2015-12-03 |
RU2553453C2 (en) | 2015-06-20 |
RU2012122208A (en) | 2013-12-10 |
US8846655B2 (en) | 2014-09-30 |
JP5781527B2 (en) | 2015-09-24 |
EP2493852B1 (en) | 2014-04-09 |
CN102741226B (en) | 2016-01-06 |
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