IN2012DN01873A - - Google Patents
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- Publication number
- IN2012DN01873A IN2012DN01873A IN1873DEN2012A IN2012DN01873A IN 2012DN01873 A IN2012DN01873 A IN 2012DN01873A IN 1873DEN2012 A IN1873DEN2012 A IN 1873DEN2012A IN 2012DN01873 A IN2012DN01873 A IN 2012DN01873A
- Authority
- IN
- India
- Prior art keywords
- protective group
- formula
- diels
- azabicyclo
- hept
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Enantiomerically enriched (1 S,4R)-2-oxa-3-azabicyclo[2.2.1]hept-5-ene of formula wherein PG1 is an amino-protective group, are prepared from cyclopentadiene via hetero-Diels-Alder cycloaddition with protected 1-C-nitroso-P-D-ribofuranosyl halides of formula wherein X is a halogen atom selected from fluorine, chlorine, bromine and iodine, PG is a hydroxyl-protective group and PG is a 1,2-diol-protective group.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09011146 | 2009-08-31 | ||
| PCT/EP2010/005199 WO2011023374A1 (en) | 2009-08-31 | 2010-08-25 | Process for the preparation of (1s,4r)-2-oxa-3-azabicyclo[2,2.1]hept-5-enes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN01873A true IN2012DN01873A (en) | 2015-08-21 |
Family
ID=41172230
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1873DEN2012 IN2012DN01873A (en) | 2009-08-31 | 2010-08-25 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9102634B2 (en) |
| EP (1) | EP2473492B1 (en) |
| JP (2) | JP5955769B2 (en) |
| KR (2) | KR101758941B1 (en) |
| CN (1) | CN102482237B (en) |
| AU (1) | AU2010288864A1 (en) |
| BR (1) | BR112012004523A2 (en) |
| CA (1) | CA2772258C (en) |
| ES (1) | ES2556959T3 (en) |
| HK (1) | HK1168845A1 (en) |
| IL (1) | IL218322A0 (en) |
| IN (1) | IN2012DN01873A (en) |
| PL (1) | PL2473492T3 (en) |
| SI (1) | SI2473492T1 (en) |
| TW (1) | TWI518090B (en) |
| WO (1) | WO2011023374A1 (en) |
| ZA (1) | ZA201201715B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9278972B2 (en) | 2011-12-23 | 2016-03-08 | Lek Pharmaceuticals D.D. | Synthesis of triazolopyrimidine compounds |
| WO2016189542A1 (en) | 2015-05-28 | 2016-12-01 | Natco Pharma Ltd | Novel process for the preparation of sapropterin dihydrochloride and its key intermediate, l-biopterin |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8729994D0 (en) * | 1987-12-23 | 1988-02-03 | Glaxo Group Ltd | Chemical compounds |
| US5576323A (en) | 1993-12-03 | 1996-11-19 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
-
2010
- 2010-08-25 AU AU2010288864A patent/AU2010288864A1/en not_active Abandoned
- 2010-08-25 SI SI201031080T patent/SI2473492T1/en unknown
- 2010-08-25 IN IN1873DEN2012 patent/IN2012DN01873A/en unknown
- 2010-08-25 JP JP2012527221A patent/JP5955769B2/en not_active Expired - Fee Related
- 2010-08-25 US US13/392,947 patent/US9102634B2/en not_active Expired - Fee Related
- 2010-08-25 WO PCT/EP2010/005199 patent/WO2011023374A1/en active Application Filing
- 2010-08-25 ES ES10747830.7T patent/ES2556959T3/en active Active
- 2010-08-25 CA CA2772258A patent/CA2772258C/en not_active Expired - Fee Related
- 2010-08-25 PL PL10747830T patent/PL2473492T3/en unknown
- 2010-08-25 BR BR112012004523A patent/BR112012004523A2/en not_active IP Right Cessation
- 2010-08-25 EP EP10747830.7A patent/EP2473492B1/en not_active Not-in-force
- 2010-08-25 KR KR1020127007771A patent/KR101758941B1/en active IP Right Grant
- 2010-08-25 CN CN201080038452.9A patent/CN102482237B/en not_active Expired - Fee Related
- 2010-08-25 KR KR1020177003043A patent/KR20170015575A/en not_active Application Discontinuation
- 2010-08-27 TW TW099128784A patent/TWI518090B/en not_active IP Right Cessation
-
2012
- 2012-02-26 IL IL218322A patent/IL218322A0/en not_active IP Right Cessation
- 2012-03-08 ZA ZA2012/01715A patent/ZA201201715B/en unknown
- 2012-09-26 HK HK12109471.5A patent/HK1168845A1/en not_active IP Right Cessation
-
2015
- 2015-08-14 JP JP2015160176A patent/JP6121492B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP5955769B2 (en) | 2016-07-20 |
| ES2556959T3 (en) | 2016-01-21 |
| KR101758941B1 (en) | 2017-07-17 |
| EP2473492B1 (en) | 2015-10-07 |
| US20120157671A1 (en) | 2012-06-21 |
| CA2772258C (en) | 2017-11-21 |
| PL2473492T3 (en) | 2016-03-31 |
| CA2772258A1 (en) | 2011-03-03 |
| TWI518090B (en) | 2016-01-21 |
| JP6121492B2 (en) | 2017-04-26 |
| AU2010288864A1 (en) | 2012-04-19 |
| CN102482237B (en) | 2014-12-10 |
| US9102634B2 (en) | 2015-08-11 |
| EP2473492A1 (en) | 2012-07-11 |
| BR112012004523A2 (en) | 2015-09-08 |
| SI2473492T1 (en) | 2016-01-29 |
| JP2016028038A (en) | 2016-02-25 |
| HK1168845A1 (en) | 2013-01-11 |
| KR20170015575A (en) | 2017-02-08 |
| IL218322A0 (en) | 2012-04-30 |
| WO2011023374A1 (en) | 2011-03-03 |
| ZA201201715B (en) | 2012-11-28 |
| CN102482237A (en) | 2012-05-30 |
| KR20120092101A (en) | 2012-08-20 |
| TW201109340A (en) | 2011-03-16 |
| JP2013503207A (en) | 2013-01-31 |
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