IN2012DN00403A - - Google Patents

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Publication number
IN2012DN00403A
IN2012DN00403A IN403DEN2012A IN2012DN00403A IN 2012DN00403 A IN2012DN00403 A IN 2012DN00403A IN 403DEN2012 A IN403DEN2012 A IN 403DEN2012A IN 2012DN00403 A IN2012DN00403 A IN 2012DN00403A
Authority
IN
India
Prior art keywords
nucleic acid
acid molecule
seq
encodes
terpene synthase
Prior art date
Application number
Inventor
Katherine Grace Zulak
Christopher Jones
Jessie Moniodia
Joerg Bohlmann
Original Assignee
Univ Western Australia
Forest Products Commission
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2009903016A external-priority patent/AU2009903016A0/en
Application filed by Univ Western Australia, Forest Products Commission, Univ British Columbia filed Critical Univ Western Australia
Publication of IN2012DN00403A publication Critical patent/IN2012DN00403A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P15/00—Preparation of compounds containing at least three condensed carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/527—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03081—Exo-alpha-bergamotene synthase (4.2.3.81)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03082—Alpha-santalene synthase (4.2.3.82)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03083—Beta-santalene synthase (4.2.3.83)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

An isolated nucleic acid molecule that encodes a terpene synthase and is selected from among: a) a nucleic acid molecule comprising the sequence of nucleotides set forth in SEQ ID NO: 1, SEQ ID NO: 3 or SEQ ID NO: 5; b) a nucleic acid molecule that is a fragment of (a); c) a nucleic acid molecule comprising a sequence of nucleotides that is complementary to (a)-or (b); and d) a nucleic acid molecule that encodes a terpene synthase having at least or at least about or at least about 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, 96%, 97%, 98%, 99% identity to any one of (a)-(c); wherein the nucleic acid molecule encodes a terpene synthase.
IN403DEN2012 2009-06-29 2010-06-25 IN2012DN00403A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2009903016A AU2009903016A0 (en) 2009-06-29 Novel Gene and Product
PCT/AU2010/000802 WO2011000026A1 (en) 2009-06-29 2010-06-25 Terpene synthases from santalum

Publications (1)

Publication Number Publication Date
IN2012DN00403A true IN2012DN00403A (en) 2015-08-21

Family

ID=43410351

Family Applications (1)

Application Number Title Priority Date Filing Date
IN403DEN2012 IN2012DN00403A (en) 2009-06-29 2010-06-25

Country Status (8)

Country Link
US (3) US8569025B2 (en)
EP (1) EP2449107B1 (en)
CN (1) CN102725410B (en)
BR (1) BRPI1014137A2 (en)
CA (1) CA2766810C (en)
IL (1) IL217221A0 (en)
IN (1) IN2012DN00403A (en)
WO (1) WO2011000026A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY153871A (en) 2008-04-23 2015-03-31 Danisco Us Inc Isoprene synthase variants for improved microbial production of isoprene
PL2772543T3 (en) * 2008-12-11 2017-09-29 Firmenich Sa Enzymatic process for producing beta-santalene and the corresponding enzyme
AU2015201051B2 (en) * 2008-12-11 2017-03-02 Firmenich Sa Method for producing beta-santalene
CN102656265A (en) 2009-04-23 2012-09-05 丹尼斯科美国公司 Three-dimensional structure of isoprene synthase and its use thereof for generating variants
EP2449107B1 (en) 2009-06-29 2015-04-08 The University Of Western Australia Terpene synthases from santalum
WO2012058494A2 (en) 2010-10-27 2012-05-03 Danisco Us Inc. Isoprene synthase variants for improved production of isoprene
EP2633042A1 (en) 2010-10-29 2013-09-04 Allylix, Inc. Modified valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof
AU2012343263B2 (en) 2011-11-21 2017-10-26 The University Of British Columbia Diterpene synthases and method for producing diterpenoids
US9550815B2 (en) 2012-01-23 2017-01-24 University Of British Columbia ABC terpenoid transporters and methods of using the same
US9163263B2 (en) 2012-05-02 2015-10-20 The Goodyear Tire & Rubber Company Identification of isoprene synthase variants with improved properties for the production of isoprene
ES2911701T3 (en) * 2012-11-01 2022-05-20 Univ British Columbia Cytochrome P450 and cytochrome P450 reductase polypeptides, encoding nucleic acid molecules, and uses thereof
PT2970934T (en) 2013-03-14 2017-11-21 Inc Evolva Valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof
WO2015153501A2 (en) * 2014-03-31 2015-10-08 Allylix, Inc. Modified santalene synthase polypeptides, encoding nucleic acid molecules and uses thereof
ES2709926T3 (en) 2014-12-02 2019-04-22 Firmenich & Cie Intermediates and procedure for the preparation of sandalwood oil building blocks
CN108239630B (en) * 2016-12-27 2021-07-16 武汉臻智生物科技有限公司 Method for modifying terpene synthase
NL2018457B1 (en) * 2017-03-02 2018-09-21 Isobionics B V Santalene Synthase
US20220315911A1 (en) * 2017-03-02 2022-10-06 Isobionics B.V. Santalene synthase
NL2019473B1 (en) 2017-09-01 2019-03-11 Isobionics B V Terpene Synthase producing patchoulol and elemol, and preferably also pogostol
CN110093329B (en) * 2018-01-30 2023-07-04 深圳艾格鑫科技有限公司 Terpene synthase and application thereof
CN108660128B (en) * 2018-05-18 2021-07-13 江苏省农业科学院 Alfalfa terpene synthase, encoding gene, vector, polyclonal antibody and application thereof
CN111434773B (en) * 2019-01-15 2021-06-18 天津大学 Recombinant yeast for high-yield sandalwood oil and construction method and application thereof
CN111073941B (en) * 2019-09-12 2022-10-14 天津芸熙生物技术有限公司 Preparation process of sandalwood polypeptide
CN112852650B (en) * 2019-11-27 2023-04-14 暨南大学 Saccharomyces cerevisiae engineering bacterium for high yield of santalene and santalol and construction method and application thereof
EP4058589A1 (en) * 2019-12-23 2022-09-21 Firmenich SA Biochemically produced sandalwood oil
BR112022024475A2 (en) 2020-06-04 2022-12-27 Isobionics B V SANTALENE BETA SYNTHETIC SYNTHASE, SYNTHETIC NUCLEIC ACID, EXPRESSION CASSETTE, METHOD FOR PRODUCING A COMPOSITION, NON-HUMAN HOST CELL, COMPOSITION, AND, USE OF ANY OF THE SYNTHETIC SANTALENE SYNTHESES
CN112410362A (en) * 2020-11-06 2021-02-26 浙江万里学院 Rhododendron micranthum TPS gene, primer for cloning Rhododendron micranthum TPS gene, cloning method and application thereof
CN112831519B (en) * 2020-12-28 2022-10-21 上海交通大学 Method for preparing santalol by utilizing sweet wormwood herbs
CN113025594B (en) * 2021-03-04 2022-05-31 安徽农业大学 Polypeptide, nucleic acid and application of polypeptide and nucleic acid in synthesis of geraniol
CN114457067A (en) * 2022-02-10 2022-05-10 中国科学院天津工业生物技术研究所 Method for quickly removing errors in DNA synthesis at low cost

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FR2881143B1 (en) 2005-01-27 2010-12-17 Librophyt SYSTEM FOR PRODUCING TERPENOIDS IN PLANTS
EP2311940B1 (en) 2005-06-17 2017-08-09 Firmenich SA Novel sesquiterpene synthases and methods of their use
WO2009044336A2 (en) 2007-10-05 2009-04-09 Firmenich Sa Method for producing diterpenes
CN101978062B (en) 2008-03-06 2014-04-02 弗门尼舍有限公司 Method for producing alpha-santalene
PL2772543T3 (en) * 2008-12-11 2017-09-29 Firmenich Sa Enzymatic process for producing beta-santalene and the corresponding enzyme
EP2449107B1 (en) 2009-06-29 2015-04-08 The University Of Western Australia Terpene synthases from santalum
AU2012343263B2 (en) 2011-11-21 2017-10-26 The University Of British Columbia Diterpene synthases and method for producing diterpenoids
US9550815B2 (en) 2012-01-23 2017-01-24 University Of British Columbia ABC terpenoid transporters and methods of using the same

Also Published As

Publication number Publication date
US20150167021A1 (en) 2015-06-18
EP2449107B1 (en) 2015-04-08
CA2766810A1 (en) 2011-01-06
US8993284B2 (en) 2015-03-31
US20140196166A1 (en) 2014-07-10
WO2011000026A1 (en) 2011-01-06
CN102725410B (en) 2016-03-16
IL217221A0 (en) 2012-02-29
US8569025B2 (en) 2013-10-29
CA2766810C (en) 2017-10-10
EP2449107A4 (en) 2013-01-02
EP2449107A1 (en) 2012-05-09
US20120208173A1 (en) 2012-08-16
US9260728B2 (en) 2016-02-16
BRPI1014137A2 (en) 2015-08-25
CN102725410A (en) 2012-10-10

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