IL97222A - שיטה ומגיב לקביעת שינויים מיוחדים לנוקליאוטיד - Google Patents
שיטה ומגיב לקביעת שינויים מיוחדים לנוקליאוטידInfo
- Publication number
- IL97222A IL97222A IL9722291A IL9722291A IL97222A IL 97222 A IL97222 A IL 97222A IL 9722291 A IL9722291 A IL 9722291A IL 9722291 A IL9722291 A IL 9722291A IL 97222 A IL97222 A IL 97222A
- Authority
- IL
- Israel
- Prior art keywords
- nucleotide
- detection step
- primer
- sequence
- detection
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48200590A | 1990-02-16 | 1990-02-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL97222A0 IL97222A0 (en) | 1992-05-25 |
| IL97222A true IL97222A (he) | 1995-08-31 |
Family
ID=23914258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9722291A IL97222A (he) | 1990-02-16 | 1991-02-12 | שיטה ומגיב לקביעת שינויים מיוחדים לנוקליאוטיד |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0648280B1 (he) |
| JP (1) | JP2786011B2 (he) |
| AT (1) | ATE180019T1 (he) |
| AU (1) | AU642709B2 (he) |
| CA (1) | CA2071537C (he) |
| DE (2) | DE648280T1 (he) |
| DK (1) | DK0648280T3 (he) |
| ES (1) | ES2072235T3 (he) |
| FI (1) | FI102297B1 (he) |
| GR (2) | GR950300047T1 (he) |
| HU (1) | HU211058B (he) |
| IE (1) | IE910525A1 (he) |
| IL (1) | IL97222A (he) |
| NO (1) | NO311529B1 (he) |
| NZ (1) | NZ237134A (he) |
| PT (1) | PT96776B (he) |
| WO (1) | WO1991013075A2 (he) |
| ZA (1) | ZA911152B (he) |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5547839A (en) | 1989-06-07 | 1996-08-20 | Affymax Technologies N.V. | Sequencing of surface immobilized polymers utilizing microflourescence detection |
| US6013431A (en) | 1990-02-16 | 2000-01-11 | Molecular Tool, Inc. | Method for determining specific nucleotide variations by primer extension in the presence of mixture of labeled nucleotides and terminators |
| US6004744A (en) * | 1991-03-05 | 1999-12-21 | Molecular Tool, Inc. | Method for determining nucleotide identity through extension of immobilized primer |
| WO1992016180A2 (en) * | 1991-03-13 | 1992-10-01 | Siska Diagnostics, Inc. | Detection of 3'-azido-3'-deoxythymidine resistance |
| US7026115B1 (en) | 1991-09-24 | 2006-04-11 | Keygene N.V. | Selective restriction fragment amplification: fingerprinting |
| US20100267023A1 (en) | 1992-09-24 | 2010-10-21 | Keygene N.V. | Selective restriction fragment amplification: fingerprinting |
| GB9208000D0 (en) * | 1992-04-10 | 1992-05-27 | Univ London | Quantitative viral assay |
| US5750335A (en) * | 1992-04-24 | 1998-05-12 | Massachusetts Institute Of Technology | Screening for genetic variation |
| EP0655090B1 (en) * | 1992-04-27 | 2000-12-27 | The Trustees Of Dartmouth College | Detection of gene sequences in biological fluids |
| GB9210176D0 (en) † | 1992-05-12 | 1992-06-24 | Cemu Bioteknik Ab | Chemical method |
| JPH06509946A (ja) * | 1992-06-17 | 1994-11-10 | シティ・オブ・ホープ | 核酸を検出し識別する方法 |
| DE69232846T2 (de) * | 1992-06-17 | 2003-08-21 | City Of Hope Duarte | Verfahren zum nachweis und unterscheiden von nukleinsäuresequenzen |
| US5981176A (en) | 1992-06-17 | 1999-11-09 | City Of Hope | Method of detecting and discriminating between nucleic acid sequences |
| US5710028A (en) * | 1992-07-02 | 1998-01-20 | Eyal; Nurit | Method of quick screening and identification of specific DNA sequences by single nucleotide primer extension and kits therefor |
| AU4770393A (en) * | 1992-07-02 | 1994-01-31 | Diagenetics Gamidor Ltd | Methods of single nucleotide primer extension to detect specific alleles and kits therefor |
| US5605798A (en) | 1993-01-07 | 1997-02-25 | Sequenom, Inc. | DNA diagnostic based on mass spectrometry |
| US6153379A (en) * | 1993-06-22 | 2000-11-28 | Baylor College Of Medicine | Parallel primer extension approach to nucleic acid sequence analysis |
| US7001722B1 (en) | 1993-06-22 | 2006-02-21 | Baylor College Of Medicine | Parallel primer extension approach to nucleic acid sequence analysis |
| US6071699A (en) | 1996-06-07 | 2000-06-06 | California Institute Of Technology | Nucleic acid mediated electron transfer |
| CA2111503A1 (en) * | 1993-12-15 | 1995-06-16 | Mcgill University | Apolipoprotein e polymorphism and alzheimer's disease |
| US6428955B1 (en) | 1995-03-17 | 2002-08-06 | Sequenom, Inc. | DNA diagnostics based on mass spectrometry |
| GB9507238D0 (en) | 1995-04-07 | 1995-05-31 | Isis Innovation | Detecting dna sequence variations |
| GB9517914D0 (en) * | 1995-09-02 | 1995-11-01 | Tepnel Medical Ltd | Identification of bases in nucleic acid sequences |
| NO954667D0 (no) * | 1995-11-17 | 1995-11-17 | Dagfinn Oegreid | Fremgangsmåte til deteksjon av Ki-ras mutasjoner |
| AU2320597A (en) | 1996-03-19 | 1997-10-10 | Molecular Tool, Inc. | Method for determining the nucleotide sequence of a polynucleotide |
| WO1998002574A1 (fr) * | 1996-07-11 | 1998-01-22 | Wakunaga Pharmaceutical Co., Ltd. | Procede pour l'examen d'acides nucleiques et kits d'examen |
| WO1998006736A1 (en) | 1996-08-14 | 1998-02-19 | Life Technologies, Inc. | Stable compositions for nucleic acid amplification and sequencing |
| GB9620209D0 (en) | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
| US7045285B1 (en) | 1996-11-05 | 2006-05-16 | Clinical Micro Sensors, Inc. | Electronic transfer moieties attached to peptide nucleic acids |
| US7381525B1 (en) | 1997-03-07 | 2008-06-03 | Clinical Micro Sensors, Inc. | AC/DC voltage apparatus for detection of nucleic acids |
| US6133436A (en) * | 1996-11-06 | 2000-10-17 | Sequenom, Inc. | Beads bound to a solid support and to nucleic acids |
| US6140053A (en) | 1996-11-06 | 2000-10-31 | Sequenom, Inc. | DNA sequencing by mass spectrometry via exonuclease degradation |
| GB9626815D0 (en) | 1996-12-23 | 1997-02-12 | Cemu Bioteknik Ab | Method of sequencing DNA |
| US5945284A (en) * | 1997-05-27 | 1999-08-31 | The Perkin-Elmer Corporation | Length determination of nucleic acid repeat sequences by discontinuous primer extension |
| US6309829B1 (en) | 1997-05-27 | 2001-10-30 | Pe Corporation (Ny) | Length determination of nucleic acid repeat sequences by discontinuous primer extension |
| US6566101B1 (en) | 1997-06-16 | 2003-05-20 | Anthony P. Shuber | Primer extension methods for detecting nucleic acids |
| US5888778A (en) * | 1997-06-16 | 1999-03-30 | Exact Laboratories, Inc. | High-throughput screening method for identification of genetic mutations or disease-causing microorganisms using segmented primers |
| EP0892068A1 (en) * | 1997-07-18 | 1999-01-20 | Genset Sa | Method for generating a high density linkage disequilibrium-based map of the human genome |
| GB9715034D0 (en) * | 1997-07-18 | 1997-09-24 | Zeneca Ltd | Assay |
| US7105353B2 (en) | 1997-07-18 | 2006-09-12 | Serono Genetics Institute S.A. | Methods of identifying individuals for inclusion in drug studies |
| US7745142B2 (en) | 1997-09-15 | 2010-06-29 | Molecular Devices Corporation | Molecular modification assays |
| US6537751B1 (en) | 1998-04-21 | 2003-03-25 | Genset S.A. | Biallelic markers for use in constructing a high density disequilibrium map of the human genome |
| CA2245039A1 (en) | 1998-08-13 | 2000-02-13 | Vito Scalia | Primer-specific and mispair extension assay for identifying gene variation |
| EP1108065A1 (en) * | 1998-08-28 | 2001-06-20 | Sangtec Molecular Diagnostics AB | A method for measuring a patient's ability to metabolise certain drugs |
| DE19855469C2 (de) * | 1998-12-01 | 2001-01-11 | Michael Esrich | Verfahren zur Bestimmung des Apolipoprotein-E-Genotyps in einer menschlichen Probe |
| US6503718B2 (en) | 1999-01-10 | 2003-01-07 | Exact Sciences Corporation | Methods for detecting mutations using primer extension for detecting disease |
| US6280947B1 (en) | 1999-08-11 | 2001-08-28 | Exact Sciences Corporation | Methods for detecting nucleotide insertion or deletion using primer extension |
| US6573047B1 (en) | 1999-04-13 | 2003-06-03 | Dna Sciences, Inc. | Detection of nucleotide sequence variation through fluorescence resonance energy transfer label generation |
| US20060275782A1 (en) | 1999-04-20 | 2006-12-07 | Illumina, Inc. | Detection of nucleic acid reactions on bead arrays |
| AU4476900A (en) | 1999-04-20 | 2000-11-02 | Illumina, Inc. | Detection of nucleic acid reactions on bead arrays |
| US7056661B2 (en) | 1999-05-19 | 2006-06-06 | Cornell Research Foundation, Inc. | Method for sequencing nucleic acid molecules |
| JP2001245698A (ja) * | 1999-11-22 | 2001-09-11 | Xiao Bing Wang | 核酸検出法 |
| WO2001040520A1 (en) | 1999-12-02 | 2001-06-07 | Dna Sciences, Inc. | Methods for determining single nucleotide variations and genotyping |
| US6518024B2 (en) | 1999-12-13 | 2003-02-11 | Motorola, Inc. | Electrochemical detection of single base extension |
| US6762018B1 (en) | 1999-12-23 | 2004-07-13 | Tetragen Sa | Analysis of nucleotide polymorphisms at a site |
| WO2001061043A2 (en) | 2000-02-16 | 2001-08-23 | Illumina, Inc. | Parallel genotyping of multiple patient samples |
| US6355433B1 (en) | 2000-06-02 | 2002-03-12 | Dna Sciences, Inc. | Determination of nucleotide sequence variations through limited primer extension |
| SG115374A1 (en) * | 2000-07-17 | 2005-10-28 | Xiao Bing Wang | Detection of sequence variation of nucleic acid by shifted termination analysis |
| CH699253B1 (de) * | 2000-09-18 | 2010-02-15 | Eidgenoessische Forschungsanst | Verfahren zur Charakterisierung und/oder Identifikation von Genomen. |
| AU2002227156A1 (en) | 2000-12-01 | 2002-06-11 | Visigen Biotechnologies, Inc. | Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity |
| US6428964B1 (en) | 2001-03-15 | 2002-08-06 | Exact Sciences Corporation | Method for alteration detection |
| US6803201B2 (en) | 2002-01-24 | 2004-10-12 | Stratagene | Compositions and methods for polynucleotide sequence determination |
| JP4143756B2 (ja) | 2002-06-21 | 2008-09-03 | 財団法人名古屋産業科学研究所 | 心筋梗塞のリスク診断方法 |
| DE10245145B4 (de) * | 2002-09-27 | 2004-12-02 | IPK-Institut für Pflanzengenetik und Kulturpflanzenforschung | Verfahren zum Nachweis von SNPs auf polydimensionalen Microarrays |
| JP3867926B2 (ja) | 2002-10-29 | 2007-01-17 | 独立行政法人理化学研究所 | 核酸の増幅法 |
| TW201037080A (en) | 2003-12-25 | 2010-10-16 | Danform Kk | Method of amplifying nucleic acid and method of detecting mutated nucleic acid using the same |
| WO2006044078A2 (en) | 2004-09-17 | 2006-04-27 | Pacific Biosciences Of California, Inc. | Apparatus and method for analysis of molecules |
| US7170050B2 (en) | 2004-09-17 | 2007-01-30 | Pacific Biosciences Of California, Inc. | Apparatus and methods for optical analysis of molecules |
| WO2006047787A2 (en) | 2004-10-27 | 2006-05-04 | Exact Sciences Corporation | Method for monitoring disease progression or recurrence |
| US9777314B2 (en) | 2005-04-21 | 2017-10-03 | Esoterix Genetic Laboratories, Llc | Analysis of heterogeneous nucleic acid samples |
| EP3045542B1 (en) | 2008-03-28 | 2016-11-16 | Pacific Biosciences of California, Inc. | Methods for nucleic acid sequencing |
| WO2012049279A1 (en) | 2010-10-14 | 2012-04-19 | Universitaet Des Saarlandes | MEANS AND METHODS APPLYING SINGLE NUCLEOTIDE PRIMER EXTENSION WITH ION PAIR-, REVERSED-PHASE HPLC (SIRPH) FOR THE DIAGNOSIS OF SNPs |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8311018D0 (en) * | 1983-04-22 | 1983-05-25 | Amersham Int Plc | Detecting mutations in dna |
| US4851331A (en) * | 1986-05-16 | 1989-07-25 | Allied Corporation | Method and kit for polynucleotide assay including primer-dependant DNA polymerase |
| AU622104B2 (en) * | 1987-03-11 | 1992-04-02 | Sangtec Molecular Diagnostics Ab | Method of assaying of nucleic acids, a reagent combination and kit therefore |
| FI80476C (fi) * | 1987-10-09 | 1990-06-11 | Orion Yhtymae Oy | Foerbaettrat hybridisationsfoerfarande, vid foerfarandet anvaent redskap och reagensfoerpackning. |
| IE61148B1 (en) * | 1988-03-10 | 1994-10-05 | Ici Plc | Method of detecting nucleotide sequences |
| ATE108491T1 (de) * | 1988-03-18 | 1994-07-15 | Baylor College Medicine | Mutationsnachweis durch kompetitiven oligonukleotid-priming. |
| WO1989009835A1 (en) * | 1988-04-08 | 1989-10-19 | The Salk Institute For Biological Studies | Ligase-based amplification method |
| AU3694689A (en) * | 1988-04-28 | 1989-11-24 | Mark H. Skolnick | Amplified sequence polymorphisms (asps) |
| AU629845B2 (en) * | 1988-08-30 | 1992-10-15 | Abbott Laboratories | Detection and amplification of target nucleic acid sequences |
| CA2002076A1 (en) * | 1988-11-21 | 1990-05-21 | Brent A. Burdick | Diagnostic kit and method using a solid phase capture means for detecting nucleic acids |
| DK175170B1 (da) * | 1988-11-29 | 2004-06-21 | Sangtec Molecular Diagnostics | Fremgangsmåde og reagenskombination til bestemmmelse af nukleotidsekvenser |
| AU656514B2 (en) * | 1989-02-13 | 1995-02-09 | Geneco Pty Ltd | Detection of a nucleic acid sequence or a change therein |
| AU5640090A (en) * | 1989-03-21 | 1990-11-05 | Collaborative Research Inc. | A dna diagnostic test using an exonuclease activity |
-
1991
- 1991-02-12 IL IL9722291A patent/IL97222A/he active IP Right Review Request
- 1991-02-15 ZA ZA911152A patent/ZA911152B/xx unknown
- 1991-02-15 DK DK91903942T patent/DK0648280T3/da active
- 1991-02-15 DE DE0648280T patent/DE648280T1/de active Pending
- 1991-02-15 AT AT91903942T patent/ATE180019T1/de not_active IP Right Cessation
- 1991-02-15 CA CA002071537A patent/CA2071537C/en not_active Expired - Fee Related
- 1991-02-15 PT PT96776A patent/PT96776B/pt not_active IP Right Cessation
- 1991-02-15 ES ES91903942T patent/ES2072235T3/es not_active Expired - Lifetime
- 1991-02-15 JP JP3503987A patent/JP2786011B2/ja not_active Expired - Fee Related
- 1991-02-15 WO PCT/FI1991/000046 patent/WO1991013075A2/en active IP Right Grant
- 1991-02-15 AU AU72351/91A patent/AU642709B2/en not_active Ceased
- 1991-02-15 IE IE052591A patent/IE910525A1/en not_active IP Right Cessation
- 1991-02-15 DE DE69131233T patent/DE69131233T2/de not_active Expired - Fee Related
- 1991-02-15 NZ NZ237134A patent/NZ237134A/en unknown
- 1991-02-15 EP EP91903942A patent/EP0648280B1/en not_active Expired - Lifetime
- 1991-02-15 HU HU91516A patent/HU211058B/hu not_active IP Right Cessation
-
1992
- 1992-08-10 NO NO19923116A patent/NO311529B1/no unknown
- 1992-08-14 FI FI923653A patent/FI102297B1/fi not_active IP Right Cessation
-
1995
- 1995-07-31 GR GR950300047T patent/GR950300047T1/el unknown
-
1999
- 1999-07-14 GR GR990401879T patent/GR3030790T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1991013075A2 (en) | 1991-09-05 |
| NO923116L (no) | 1992-08-10 |
| EP0648280B1 (en) | 1999-05-12 |
| HUT61330A (en) | 1992-12-28 |
| NO311529B1 (no) | 2001-12-03 |
| ATE180019T1 (de) | 1999-05-15 |
| IL97222A0 (en) | 1992-05-25 |
| CA2071537C (en) | 2003-02-11 |
| IE910525A1 (en) | 1991-08-28 |
| DE69131233D1 (de) | 1999-06-17 |
| NO923116D0 (no) | 1992-08-10 |
| FI923653A0 (fi) | 1992-08-14 |
| PT96776B (pt) | 1998-05-29 |
| FI102297B (fi) | 1998-11-13 |
| ES2072235T1 (es) | 1995-07-16 |
| AU642709B2 (en) | 1993-10-28 |
| DE648280T1 (de) | 1995-11-30 |
| DE69131233T2 (de) | 1999-11-04 |
| NZ237134A (en) | 1992-06-25 |
| FI102297B1 (fi) | 1998-11-13 |
| JP2786011B2 (ja) | 1998-08-13 |
| AU7235191A (en) | 1991-09-18 |
| JPH05504477A (ja) | 1993-07-15 |
| WO1991013075A3 (en) | 1991-10-17 |
| EP0648280A1 (en) | 1995-04-19 |
| ZA911152B (en) | 1991-11-27 |
| DK0648280T3 (da) | 1999-11-01 |
| GR3030790T3 (en) | 1999-11-30 |
| ES2072235T3 (es) | 1999-07-16 |
| CA2071537A1 (en) | 1991-08-17 |
| GR950300047T1 (en) | 1995-07-31 |
| HU211058B (en) | 1995-10-30 |
| HU910516D0 (en) | 1991-09-30 |
| PT96776A (pt) | 1991-10-31 |
| FI923653A (fi) | 1992-08-14 |
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