IL95429A - Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production - Google Patents

Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production

Info

Publication number
IL95429A
IL95429A IL95429A IL9542990A IL95429A IL 95429 A IL95429 A IL 95429A IL 95429 A IL95429 A IL 95429A IL 9542990 A IL9542990 A IL 9542990A IL 95429 A IL95429 A IL 95429A
Authority
IL
Israel
Prior art keywords
collagen
tissue equivalents
production
living tissue
hydrated
Prior art date
Application number
IL95429A
Other languages
English (en)
Other versions
IL95429A0 (en
Original Assignee
Organogenesis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organogenesis filed Critical Organogenesis
Publication of IL95429A0 publication Critical patent/IL95429A0/xx
Publication of IL95429A publication Critical patent/IL95429A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0697Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698Skin equivalents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60Materials for use in artificial skin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02Membranes; Filters
    • C12M25/04Membranes; Filters in combination with well or multiwell plates, i.e. culture inserts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/09Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/094Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323Adult fibroblasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • C12N2533/54Collagen; Gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Sustainable Development (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL95429A 1989-09-15 1990-08-20 Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production IL95429A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40805289A 1989-09-15 1989-09-15

Publications (2)

Publication Number Publication Date
IL95429A0 IL95429A0 (en) 1991-06-30
IL95429A true IL95429A (en) 1997-09-30

Family

ID=23614662

Family Applications (1)

Application Number Title Priority Date Filing Date
IL95429A IL95429A (en) 1989-09-15 1990-08-20 Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production

Country Status (12)

Country Link
US (1) US5536656A (de)
EP (1) EP0418035B1 (de)
JP (1) JPH03151977A (de)
KR (1) KR940001379B1 (de)
AT (1) ATE119194T1 (de)
AU (1) AU6215690A (de)
CA (2) CA2298856C (de)
DE (1) DE69017324T2 (de)
DK (1) DK0418035T3 (de)
ES (1) ES2071778T3 (de)
IE (1) IE903340A1 (de)
IL (1) IL95429A (de)

Families Citing this family (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5888720A (en) * 1992-10-27 1999-03-30 Yissum Research And Development Company Of The Hebrew University Of Jerusalem In vitro micro-organs
CA2119064A1 (en) * 1993-03-17 1994-09-18 Richard A. Berg Dermal-epidermal in vitro test system
GB9306449D0 (en) * 1993-03-29 1993-05-19 Nat Heart Research Fund Tissue equivalents
CA2188563C (en) 1994-04-29 2005-08-02 Andrew W. Buirge Stent with collagen
US5665114A (en) * 1994-08-12 1997-09-09 Meadox Medicals, Inc. Tubular expanded polytetrafluoroethylene implantable prostheses
US5891558A (en) * 1994-11-22 1999-04-06 Tissue Engineering, Inc. Biopolymer foams for use in tissue repair and reconstruction
US6419920B1 (en) 1995-10-25 2002-07-16 Trans Karyotic Therapies, Inc. Hybrid matrix implants and explants
US5965125A (en) 1995-10-25 1999-10-12 Transkaryotic Therapies, Inc. Hybrid matrix implants and explants
US5955353A (en) * 1997-05-22 1999-09-21 Excorp Medical, Inc. Hollow fiber bioreactor with an extrafilament flow plug
US20020086423A1 (en) * 1997-09-09 2002-07-04 Toshiaki Takezawa Hydrogel thin film containing extracellular matrix components
US6498138B1 (en) 1998-03-11 2002-12-24 University Of Southern California Method of promoting production of living tissue equivalents
US6129757A (en) 1998-05-18 2000-10-10 Scimed Life Systems Implantable members for receiving therapeutically useful compositions
PT1612265E (pt) * 1998-11-19 2013-03-14 Organogenesis Inc Construções de tecidos por bioengenharia e métodos de produção e utilização das mesmas
US7001746B1 (en) * 1999-01-29 2006-02-21 Artecel Sciences, Inc. Methods and compositions for the differentiation of human preadipocytes into adipocytes
WO2000047129A2 (en) * 1999-02-11 2000-08-17 The General Hospital Corporation Microfabricated membranes and matrices
US6197061B1 (en) * 1999-03-01 2001-03-06 Koichi Masuda In vitro production of transplantable cartilage tissue cohesive cartilage produced thereby, and method for the surgical repair of cartilage damage
DE60036385T2 (de) 1999-06-21 2008-06-26 The General Hospital Corp., Boston Zellkultursysteme und verfahren für einrichtungen zur organunterstützung
CA2383398C (en) * 1999-08-23 2013-06-11 Organogenesis, Inc. Skin care compositions and treatments
EP1918366A1 (de) 2000-02-26 2008-05-07 Artecel, Inc. Pluripotente Stammzellen aus Bindegewebszellen aus dem Fettgewebe und Verwendungen dafür
AU3869501A (en) * 2000-02-26 2001-09-03 Artecel Sciences Inc Pleuripotent stem cells generated from adipose tissue-derived stromal cells and uses thereof
US7582292B2 (en) 2000-02-26 2009-09-01 Artecel, Inc. Adipose tissue derived stromal cells for the treatment of neurological disorders
US20040023907A1 (en) * 2000-05-31 2004-02-05 Christoph Dieterich Infection model
CA2410956C (en) 2000-05-31 2012-12-04 Michaela Noll Three-dimensional skin model
US7144729B2 (en) * 2000-09-01 2006-12-05 Dfb Pharmaceuticals, Inc. Methods and compositions for tissue regeneration
MXPA03002415A (es) * 2000-09-18 2004-07-08 Organogenesis Inc Metodo para tratar a un paciente que utiliza una construccion de tejido conectivo cultivado.
EP1832300A3 (de) * 2000-09-18 2008-02-27 Organogenesis Inc. Verfahren zur Behandlung eines Patienten unter Verwendung eines kultivierten Bindegewebekonstrukts
US7041868B2 (en) 2000-12-29 2006-05-09 Kimberly-Clark Worldwide, Inc. Bioabsorbable wound dressing
US6974697B2 (en) * 2001-03-02 2005-12-13 Stratech Corporation Skin substitutes with improved barrier function
CA2439899C (en) * 2001-03-02 2015-09-29 Stratatech Corporation Improved skin substitutes and uses thereof
US20030211793A1 (en) * 2001-03-05 2003-11-13 Eugene Bell Injectable bio-compatible material and methods of use
US7282362B2 (en) 2001-06-14 2007-10-16 Millipore Corporation Tray with protrusions
WO2003024463A1 (en) * 2001-09-15 2003-03-27 Rush-Presbyterian-St. Luke's Medical Center Stratified cartilage tissue and methods to engineer same
US20030165473A1 (en) * 2001-11-09 2003-09-04 Rush-Presbyterian-St. Luke's Medical Center Engineered intervertebral disc tissue
WO2003072128A2 (en) * 2002-02-22 2003-09-04 Ebi, L.P. Methods and compositions for treating bone or cartilage defects
US7741116B2 (en) 2002-03-06 2010-06-22 University Of Cincinnati Surgical device for skin therapy or testing
ATE465242T1 (de) * 2002-04-30 2010-05-15 Stratatech Corp Exogene angiogene wachstumsfaktoren exprimierende keratinozyten
US7229820B2 (en) * 2002-06-13 2007-06-12 Wilson Wolf Manufacturing Corporation Apparatus and method for culturing and preserving tissue constructs
WO2004013606A2 (en) * 2002-08-02 2004-02-12 Stratatech Corporation Species specific dna detection
JP4734245B2 (ja) * 2003-08-01 2011-07-27 ストラタテック コーポレーション 外因性ポリペプチドを発現するヒト皮膚等価物
FR2881434B1 (fr) * 2005-02-02 2007-05-11 Coletica Sa Dispositif de support de culture de cellules
CA2600177C (en) 2005-03-01 2011-06-14 Stratatech Corporation Human skin equivalents expressing exogenous polypeptides
CA2601595C (en) 2005-03-17 2015-02-24 Stratatech Corporation Skin substitutes with improved purity
FR2889808B1 (fr) 2005-08-17 2011-07-22 Oreal Utilisation de l'acide 8-hexadecene-1,16-dicarboxylique comme agent de soin destine a favoriser la cohesion de la couche cornee
EP1998787A4 (de) * 2006-03-03 2010-04-21 Organogenesis Inc Wiederherstellung und reparatur von oralem gewebe
FR2903702B1 (fr) 2006-07-13 2012-10-19 Oreal Equivalent d'epiderme capable de se pigmenter obtenu a partir de cellules de la matrice, procede de preparation et utilisation
US8932619B2 (en) * 2007-06-27 2015-01-13 Sofradim Production Dural repair material
US20090068250A1 (en) 2007-09-07 2009-03-12 Philippe Gravagna Bioresorbable and biocompatible compounds for surgical use
US20100278798A1 (en) * 2007-09-27 2010-11-04 The Trustees Of Columbia University In The City Of New York Methods and systems for forming biocompatible materials
NO2215212T3 (de) 2007-11-14 2018-01-27
US9308068B2 (en) 2007-12-03 2016-04-12 Sofradim Production Implant for parastomal hernia
EP3020410A1 (de) 2008-04-18 2016-05-18 Collplant Ltd. Verfahren zur regeneration und verwendung von prokollagen
US9242026B2 (en) 2008-06-27 2016-01-26 Sofradim Production Biosynthetic implant for soft tissue repair
JP5669741B2 (ja) * 2008-10-22 2015-02-12 リジーンメッド インコーポレイテッド 培養システム
AU2009313656B2 (en) * 2008-11-04 2014-02-20 Stratatech Corporation Dried and irradiated skin equivalents for ready use
US9511093B2 (en) 2009-03-23 2016-12-06 The Texas A & M University System Compositions of mesenchymal stem cells to regenerate bone
US20100330046A1 (en) 2009-05-21 2010-12-30 Stratatech Corporation Human skin substitutes expressing il-12
US9321988B2 (en) * 2009-06-18 2016-04-26 Illinois Tool Works Inc. Gas and liquid tissue culture interface
FR2949688B1 (fr) 2009-09-04 2012-08-24 Sofradim Production Tissu avec picots revetu d'une couche microporeuse bioresorbable
CN102883796B (zh) 2010-04-05 2016-04-06 Emd密理博公司 具有类似人类皮肤的渗透性的聚合物膜及其用途
FR2967163A1 (fr) 2010-11-05 2012-05-11 Centre Nat Rech Scient Procede in vitro ou ex vivo pour la maintenance en survie et la generation ou reconstruction d'un epiderme
FR2972626B1 (fr) 2011-03-16 2014-04-11 Sofradim Production Prothese comprenant un tricot tridimensionnel et ajoure
FR2976001B1 (fr) 2011-05-30 2014-10-31 Oreal Modele de cuir chevelu reconstruit et procede de screening de molecules actives
FR2977790B1 (fr) 2011-07-13 2013-07-19 Sofradim Production Prothese pour hernie ombilicale
FR2977789B1 (fr) 2011-07-13 2013-07-19 Sofradim Production Prothese pour hernie ombilicale
CN103841959A (zh) 2011-09-30 2014-06-04 索弗拉狄姆产品公司 用于输送治疗剂的多层植入物
US9526603B2 (en) 2011-09-30 2016-12-27 Covidien Lp Reversible stiffening of light weight mesh
FR2985170B1 (fr) 2011-12-29 2014-01-24 Sofradim Production Prothese pour hernie inguinale
FR2985271B1 (fr) 2011-12-29 2014-01-24 Sofradim Production Tricot a picots
FR2994185B1 (fr) 2012-08-02 2015-07-31 Sofradim Production Procede de preparation d’une couche poreuse a base de chitosane
PL226837B1 (pl) 2012-08-24 2017-09-29 Celther Polska Spółka Z Ograniczoną Odpowiedzialnością Aktywna warstwa polimerowa utworzona zpochodnych chityny zwłaszcza doopatrunku oraz jejzastosowanie
FR2995779B1 (fr) 2012-09-25 2015-09-25 Sofradim Production Prothese comprenant un treillis et un moyen de consolidation
FR2995778B1 (fr) 2012-09-25 2015-06-26 Sofradim Production Prothese de renfort de la paroi abdominale et procede de fabrication
FR2995788B1 (fr) 2012-09-25 2014-09-26 Sofradim Production Patch hemostatique et procede de preparation
US10159555B2 (en) 2012-09-28 2018-12-25 Sofradim Production Packaging for a hernia repair device
CA2905656C (en) 2013-03-13 2020-04-14 Stratatech Corporation Cryopreservation of viable human skin substitutes
EP2991692B1 (de) 2013-05-03 2019-08-21 The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. Hautersatzstoffe und verfahren zur neubildung von haarfollikeln
FR3006578B1 (fr) 2013-06-07 2015-05-29 Sofradim Production Prothese a base d’un textile pour voie laparoscopique
FR3006581B1 (fr) 2013-06-07 2016-07-22 Sofradim Production Prothese a base d’un textile pour voie laparoscopique
EP3137594B1 (de) 2014-04-30 2018-03-28 Fondazione Istituto Italiano di Tecnologia Verfahren zur herstellung eines vollständig endogenen genmanipulierten gewebe und damit hergestelltes gewebe
EP3000489B1 (de) 2014-09-24 2017-04-05 Sofradim Production Verfahren zur Herstellung einer Antihaft-Sperrschicht
EP3000432B1 (de) 2014-09-29 2022-05-04 Sofradim Production Textilbasierte Prothese für die Behandlung von Leistenbruch
EP3000433B1 (de) 2014-09-29 2022-09-21 Sofradim Production Vorrichtung zur Einführung einer Prothese zur Hernie-Behandlung in einen Einschnitt und flexible textile Prothese
EP3029189B1 (de) 2014-12-05 2021-08-11 Sofradim Production Prothetisches poröses Netz, sein Herstellungsverfahren und Hernienprothese
EP3059255B1 (de) 2015-02-17 2020-05-13 Sofradim Production Verfahren zur Herstellung einer Matrix auf Chitosanbasis mit faseroptischem Verstärkungselement
EP3085337B1 (de) 2015-04-24 2022-09-14 Sofradim Production Prothese zur unterstützung einer bruststruktur
EP3106185B1 (de) 2015-06-19 2018-04-25 Sofradim Production Synthetische prothese mit einem gewirk und einem nichtporösen film und verfahren zur formung davon
EP3195830B1 (de) 2016-01-25 2020-11-18 Sofradim Production Prothese zur hernienreparatur
FR3054449B1 (fr) 2016-07-29 2018-08-31 L'oreal Equivalent de peau a compartiments dermiques juxtaposes distincts
EP3312325B1 (de) 2016-10-21 2021-09-22 Sofradim Production Verfahren zur herstellung eines netzes mit einem daran befestigten nahtmaterial mit widerhaken und dadurch erhaltenes netz
EP3398554A1 (de) 2017-05-02 2018-11-07 Sofradim Production Prothese zur leistenbruch-reparatur
WO2018220137A1 (en) * 2017-05-31 2018-12-06 ETH Zürich Assembly for the production of tissue implants
FR3071512B1 (fr) 2017-09-28 2022-02-25 Oreal Signatures moleculaires de trois sous-populations de fibroblastes dermiques et equivalent de derme comprenant une de ces sous-populations
EP3653171B1 (de) 2018-11-16 2024-08-21 Sofradim Production Implantate zur weichgewebereparatur
US12064330B2 (en) 2020-04-28 2024-08-20 Covidien Lp Implantable prothesis for minimally invasive hernia repair
FR3111904B1 (fr) 2020-06-30 2022-10-21 Oreal Bioencre pour bioimpression d’un modèle de jonction dermo-épidermique invaginée
LU502391B1 (en) 2022-06-28 2024-01-09 Univerza V Mariboru A complex in vitro model of human skin, a process for preparation and use thereof

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2677646A (en) * 1952-03-22 1954-05-04 Lovell Chemical Company Unit for bacterial analysis
US2761813A (en) * 1953-01-21 1956-09-04 Goetz Alexander Means and method of producing and controlling cultures of microorganisms
GB1594389A (en) * 1977-06-03 1981-07-30 Max Planck Gesellschaft Dressing material for wounds
JPS55501130A (de) * 1978-12-26 1980-12-18
US4290911A (en) * 1979-02-07 1981-09-22 Fmc Corporation Agarose composition, aqueous gel and method of making same
SE7908454L (sv) * 1979-10-11 1981-04-12 Pharmacia Fine Chemicals Ab Medium for isoelektrisk fokusering
US4539716A (en) * 1981-03-19 1985-09-10 Massachusetts Institute Of Technology Fabrication of living blood vessels and glandular tissues
US4546500A (en) * 1981-05-08 1985-10-15 Massachusetts Institute Of Technology Fabrication of living blood vessels and glandular tissues
US4505266A (en) * 1981-10-26 1985-03-19 Massachusetts Institute Of Technology Method of using a fibrous lattice
US4485096A (en) * 1982-02-26 1984-11-27 Massachusetts Institute Of Technology Tissue-equivalent and method for preparation thereof
US4485097A (en) * 1982-05-26 1984-11-27 Massachusetts Institute Of Technology Bone-equivalent and method for preparation thereof
US4598045A (en) * 1982-08-25 1986-07-01 Hana Biologics, Inc. Triphasic mycoplasmatales detection method
US4734372A (en) * 1983-02-04 1988-03-29 Brown University Research Foundation Cell culturing methods and apparatus
US4578354A (en) * 1983-05-09 1986-03-25 Pfizer Inc. Immobilization of catalytically active microorganisms in agar gel fibers
DE3584188D1 (de) * 1984-05-11 1991-10-31 Terumo Corp Verfahren zur herstellung eines behaelters aus syntetischem harz.
US4604346A (en) * 1984-10-09 1986-08-05 Massachusetts Institute Of Technology Skin-equivalent prepared by the use of punch biopsy
JPS6225974A (ja) * 1985-07-25 1987-02-03 Asahi Chem Ind Co Ltd コラ−ゲンよりなるゲル状組成物
US5026649A (en) * 1986-03-20 1991-06-25 Costar Corporation Apparatus for growing tissue cultures in vitro
US4963489A (en) * 1987-04-14 1990-10-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US5032508A (en) * 1988-09-08 1991-07-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US5037656A (en) * 1986-12-04 1991-08-06 Millipore Corporation Porous membrane having hydrophilic and cell growth promotions surface and process
FR2612938B1 (fr) * 1987-03-26 1989-06-23 Cird Procede d'obtention d'un equivalent de peau et equivalent de peau correspondant
FR2612939B1 (fr) * 1987-03-26 1989-06-23 Cird Equivalent de peau
US4835102A (en) * 1987-03-31 1989-05-30 Eugene Bell Tissue equivalent test systems
US4837379A (en) * 1988-06-02 1989-06-06 Organogenesis Inc. Fibrin-collagen tissue equivalents and methods for preparation thereof
US4996154A (en) * 1989-05-04 1991-02-26 Millipore Corporation Method for growing cellular tissue
US4912057A (en) * 1989-06-13 1990-03-27 Cancer Diagnostics, Inc. Cell chamber for chemotaxis assay

Also Published As

Publication number Publication date
JPH03151977A (ja) 1991-06-28
IL95429A0 (en) 1991-06-30
EP0418035A1 (de) 1991-03-20
AU6215690A (en) 1991-08-01
CA2298856C (en) 2004-11-16
IE903340A1 (en) 1991-04-10
DE69017324D1 (de) 1995-04-06
DE69017324T2 (de) 1995-08-03
ES2071778T3 (es) 1995-07-01
EP0418035B1 (de) 1995-03-01
CA2298856A1 (en) 1991-03-16
CA2023968C (en) 2000-05-02
CA2023968A1 (en) 1991-03-16
KR940001379B1 (ko) 1994-02-21
DK0418035T3 (da) 1995-07-10
ATE119194T1 (de) 1995-03-15
JPH0553505B2 (de) 1993-08-10
US5536656A (en) 1996-07-16
KR910005893A (ko) 1991-04-27

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