IL94963A0 - Use of polyamines as ionic-channel regulating agents - Google Patents
Use of polyamines as ionic-channel regulating agentsInfo
- Publication number
- IL94963A0 IL94963A0 IL9094963A IL9496390A IL94963A0 IL 94963 A0 IL94963 A0 IL 94963A0 IL 9094963 A IL9094963 A IL 9094963A IL 9496390 A IL9496390 A IL 9496390A IL 94963 A0 IL94963 A0 IL 94963A0
- Authority
- IL
- Israel
- Prior art keywords
- polyamines
- ionic
- regulating agents
- channel regulating
- channel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/10—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/14—Amines containing amino groups bound to at least two aminoalkyl groups, e.g. diethylenetriamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
- C07C239/08—Hydroxylamino compounds or their ethers or esters
- C07C239/16—Hydroxylamino compounds or their ethers or esters having nitrogen atoms of hydroxylamino groups further bound to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37577689A | 1989-07-03 | 1989-07-03 | |
US42733389A | 1989-10-26 | 1989-10-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL94963A0 true IL94963A0 (en) | 1991-06-10 |
Family
ID=27007189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL9094963A IL94963A0 (en) | 1989-07-03 | 1990-07-03 | Use of polyamines as ionic-channel regulating agents |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0597830A1 (en) |
AU (1) | AU5957390A (en) |
CA (1) | CA2062810A1 (en) |
IL (1) | IL94963A0 (en) |
WO (1) | WO1991000853A1 (en) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5858684A (en) * | 1991-08-23 | 1999-01-12 | The Brigham And Women's Hospital, Inc. | Method of screening calcium receptor-active molecules |
US6001884A (en) * | 1991-08-23 | 1999-12-14 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US6313146B1 (en) | 1991-08-23 | 2001-11-06 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US5688938A (en) * | 1991-08-23 | 1997-11-18 | The Brigham & Women's Hospital, Inc. | Calcium receptor-active molecules |
US6011068A (en) * | 1991-08-23 | 2000-01-04 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
EP1281702B1 (en) * | 1991-08-23 | 2005-12-21 | Nps Pharmaceuticals, Inc. | Calcium receptor active molecules |
US5763569A (en) * | 1991-08-23 | 1998-06-09 | The Brigham And Women's Hospital, Inc | Calcium receptor-active molecules |
US6031003A (en) * | 1991-08-23 | 2000-02-29 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US5962314A (en) * | 1993-02-23 | 1999-10-05 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
EP0637237B1 (en) * | 1993-02-23 | 2004-05-19 | Brigham And Women's Hospital, Inc. | Calcium receptor-active molecules |
GB9320051D0 (en) * | 1993-09-29 | 1993-11-17 | Lilly Industries Ltd | Pharmaceutical compounds |
EP1553078A1 (en) | 1994-10-21 | 2005-07-13 | Nps Pharmaceuticals, Inc. | Calcium receptor-active compounds |
DE69739388D1 (en) * | 1996-05-01 | 2009-06-10 | Nps Pharma Inc | Inorganic ionic receptor active compounds |
WO1999003823A2 (en) | 1997-07-15 | 1999-01-28 | Oridigm Corporation | Novel polyamine analogues as therapeutic and diagnostic agents |
US7208528B1 (en) | 1997-07-15 | 2007-04-24 | Mediquest Therapeutics, Inc. | Polyamine analogues as therapeutic and diagnostic agents |
GB9726569D0 (en) | 1997-12-16 | 1998-02-11 | Univ Southampton | Neuroprotective agents |
CA2318004A1 (en) * | 1999-09-15 | 2001-03-15 | Oridigm Corporation | Novel polyamine analogues as therapeutic and diagnostic agents |
EP1337504A4 (en) * | 2000-11-08 | 2005-10-05 | Cellgate Inc | Novel polyamine analog-amino acid conjugates useful as anticancer agents |
AU2008201086B2 (en) * | 2001-01-08 | 2011-06-09 | Aminex Theapeutics, Inc. | Hydrophobic Polyamine Analogs and Methods for their Use |
US7432302B2 (en) | 2001-01-08 | 2008-10-07 | Mediquest Therapeutics, Inc. | Composition containing polyamine transport inhibitor and use thereof |
WO2002053519A2 (en) * | 2001-01-08 | 2002-07-11 | Mediquest Therapeutics, Inc. | Hydrophobic polyamine analogs and methods for their use |
USRE43327E1 (en) | 2001-01-08 | 2012-04-24 | Aminex Therapeutics, Inc. | Hydrophobic polyamine analogs and methods for their use |
FR2820136A1 (en) * | 2001-01-26 | 2002-08-02 | Aventis Pharma Sa | NOVEL UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION, USE THEREOF AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF |
GB0202645D0 (en) * | 2002-02-05 | 2002-03-20 | Univ Southampton | Treatment of chronic neurodegenerative diseases |
WO2006052229A1 (en) * | 2004-11-03 | 2006-05-18 | University Of Florida | Aminated polyamines |
US7423182B2 (en) | 2004-11-03 | 2008-09-09 | University Of Florida | Aminated polyamines |
FR2885129B1 (en) | 2005-04-29 | 2007-06-15 | Proskelia Sas | NOVEL DERIVATIVES OF UREEE SUBSTITUTED WITH THIAZOLE OR BENZOTHIAZOLE, PROCESS FOR THE PREPARATION THEREOF, THEIR USE AS MEDICAMENTS, THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND THE USE THEREOF |
EP3432914B1 (en) | 2016-03-25 | 2020-09-23 | Aminex Therapeutics, Inc. | Bioavailable polyamines |
JP2023545674A (en) | 2020-09-30 | 2023-10-31 | アミネックス セラピューティクス, インコーポレイテッド | Combined drug substance of polyamine transport inhibitor and DFMO |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4591605A (en) * | 1981-11-10 | 1986-05-27 | Research Foundation Of State University Of New York | Method and ingestible formulation for inhibiting the secretion of stomach acid |
-
1990
- 1990-07-03 AU AU59573/90A patent/AU5957390A/en not_active Abandoned
- 1990-07-03 IL IL9094963A patent/IL94963A0/en unknown
- 1990-07-03 CA CA002062810A patent/CA2062810A1/en not_active Abandoned
- 1990-07-03 WO PCT/US1990/003771 patent/WO1991000853A1/en not_active Application Discontinuation
- 1990-07-03 EP EP90911163A patent/EP0597830A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CA2062810A1 (en) | 1991-01-04 |
EP0597830A1 (en) | 1994-05-25 |
AU5957390A (en) | 1991-02-06 |
EP0597830A4 (en) | 1992-07-22 |
WO1991000853A1 (en) | 1991-01-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL94963A0 (en) | Use of polyamines as ionic-channel regulating agents | |
AU3428393A (en) | Use of polyamines as ionic-channel regulating agents | |
GB9104598D0 (en) | New use of 5 ht antagonists | |
ZA906579B (en) | 17 beta-acyl-4-aza-5 alpha-androst-1-ene-3-ones as 5 alpha-reductase inhibitors | |
YU54890A (en) | Agents used as pesticides | |
GB8811948D0 (en) | Composition & use | |
US5011841B1 (en) | Treatment of depression | |
ZA897614B (en) | Substituted 1,3,5-triazinetriones,processes for their preparation and their use against parasitic protozoa | |
IL82798A0 (en) | Substituted 3-amino-2-benzoyl-cyclohex-2-enones and their use as herbicides | |
ZA905187B (en) | Use of polyamines as ionic-channel regulating agents | |
ZA907147B (en) | Microemulsions of aminopolysiloxanes | |
GB8901996D0 (en) | Compounds and use | |
ZA905125B (en) | Use of retinoids | |
IL90196A0 (en) | Agents for enhancing the growth of livestock | |
GB9104599D0 (en) | New use of 5 ht antagonists | |
GB2238269B (en) | Jeweller's tool | |
OA09641A (en) | Compositions for the treatment of leishmaniasis | |
SU1726742A1 (en) | Working member of cutter-loader | |
IE882090L (en) | New use of 5-ht3-antagonists | |
IE891758L (en) | Therapeutic uses of 2', 5'-oligoadenylates | |
YU217989A (en) | Vibrator's carrier | |
ZA909799B (en) | Bruting of gem-stones | |
ZA898265B (en) | Deur-en/of vensterraamstelsel | |
HUT46187A (en) | Hothouse pink of the "valentina" kind | |
IE891471L (en) | Enhancing the growth of livestock |