IL75562A0 - New derivatives of isoxazoloquinolinone,process for their preparation,and compositions containing them - Google Patents

New derivatives of isoxazoloquinolinone,process for their preparation,and compositions containing them

Info

Publication number
IL75562A0
IL75562A0 IL75562A IL7556285A IL75562A0 IL 75562 A0 IL75562 A0 IL 75562A0 IL 75562 A IL75562 A IL 75562A IL 7556285 A IL7556285 A IL 7556285A IL 75562 A0 IL75562 A0 IL 75562A0
Authority
IL
Israel
Prior art keywords
carbon atoms
radical containing
isoxazoloquinolinone
alkyl radical
preparation
Prior art date
Application number
IL75562A
Other versions
IL75562A (en
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of IL75562A0 publication Critical patent/IL75562A0/en
Publication of IL75562A publication Critical patent/IL75562A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Lubricants (AREA)
  • Color Television Systems (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

1. Derivatives of isoxazoloquinolinone characterized in that they answer to the general formula l see diagramm : EP0168309,P8,F1 in which R represents a hydrogen, fluorine, chlorine or bromine atom, a linear alkyl radical containing from 1 to 5 carbon atoms, or branched alkyl radical containing from 3 to 5 carbon atoms, an alkoxy radical containing from 1 to 5 carbon atoms, a nitro or trifluoromethyl radical and R1 represents a phenyl radical possibly substituted by a linear alkyl radical containing from 1 to 5 carbon atoms, or a branched alkyl radical containing from 3 to 5 carbon atoms, by an alkoxy radical containing from 1 to 5 carbon atoms, or by a halogen atom.
IL75562A 1984-06-25 1985-06-19 2-phenyl isoxazolo(4,5-c)quinolin-3(2h)-ones,process for their preparation and pharmaceutical compositions containing them IL75562A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8409961A FR2566407B1 (en) 1984-06-25 1984-06-25 NOVEL ISOXAZOLOQUINOLEIN DERIVATIVES, PROCESS FOR THEIR PREPARATION, APPLICATION AS MEDICAMENTS, AND COMPOSITIONS CONTAINING THEM

Publications (2)

Publication Number Publication Date
IL75562A0 true IL75562A0 (en) 1985-10-31
IL75562A IL75562A (en) 1988-07-31

Family

ID=9305387

Family Applications (1)

Application Number Title Priority Date Filing Date
IL75562A IL75562A (en) 1984-06-25 1985-06-19 2-phenyl isoxazolo(4,5-c)quinolin-3(2h)-ones,process for their preparation and pharmaceutical compositions containing them

Country Status (17)

Country Link
EP (1) EP0168309B1 (en)
JP (1) JPS6176491A (en)
KR (1) KR860000296A (en)
AT (1) ATE32899T1 (en)
CA (1) CA1225993A (en)
DE (1) DE3561818D1 (en)
DK (1) DK284085A (en)
ES (1) ES8604599A1 (en)
FI (1) FI79322C (en)
FR (1) FR2566407B1 (en)
GR (1) GR851530B (en)
HU (1) HU192234B (en)
IL (1) IL75562A (en)
MA (1) MA20461A1 (en)
NZ (1) NZ212532A (en)
OA (1) OA08045A (en)
PT (1) PT80690B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4920117A (en) * 1989-06-09 1990-04-24 Hoechst-Roussel Pharmaceuticals Inc. 4,5,5a,6-tetrahydro-3H-isoxazolo(5,4,3-kl)acridines, pharmaceutical compositions and use
US5182290A (en) * 1991-08-27 1993-01-26 Neurogen Corporation Certain oxazoloquinolinones; a new class of GABA brain receptor ligands
JP2000514048A (en) * 1996-06-20 2000-10-24 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム Compounds and methods for providing pharmacologically active preparations and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2537140B1 (en) * 1982-12-07 1986-07-18 Roussel Uclaf NOVEL 4-HYDROXY-3-QUINOLEINE CARBOXAMIDE DERIVATIVES, SALTS THEREOF, PROCESS FOR THEIR PREPARATION, APPLICATION AS MEDICAMENTS, AND COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
OA08045A (en) 1987-01-31
FR2566407B1 (en) 1986-09-26
KR860000296A (en) 1986-01-27
EP0168309B1 (en) 1988-03-09
FI852249A0 (en) 1985-06-05
FI79322B (en) 1989-08-31
FI852249L (en) 1985-12-26
MA20461A1 (en) 1985-12-31
NZ212532A (en) 1988-08-30
ES544488A0 (en) 1986-02-01
DE3561818D1 (en) 1988-04-14
PT80690A (en) 1985-07-01
GR851530B (en) 1985-11-25
JPS6176491A (en) 1986-04-18
IL75562A (en) 1988-07-31
HUT38948A (en) 1986-07-28
FI79322C (en) 1989-12-11
FR2566407A1 (en) 1985-12-27
DK284085A (en) 1985-12-26
CA1225993A (en) 1987-08-25
ATE32899T1 (en) 1988-03-15
PT80690B (en) 1987-03-31
HU192234B (en) 1987-05-28
EP0168309A1 (en) 1986-01-15
ES8604599A1 (en) 1986-02-01
DK284085D0 (en) 1985-06-24

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