IL71735A - 1'(4-bromo-2-fluorobenzyl),-7'-chlorospiro(imidazolidine-4,3'indoline)-2,2',5-trione and its salts,their preparation and pharmaceutical compositions containing them - Google Patents

1'(4-bromo-2-fluorobenzyl),-7'-chlorospiro(imidazolidine-4,3'indoline)-2,2',5-trione and its salts,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL71735A
IL71735A IL71735A IL7173584A IL71735A IL 71735 A IL71735 A IL 71735A IL 71735 A IL71735 A IL 71735A IL 7173584 A IL7173584 A IL 7173584A IL 71735 A IL71735 A IL 71735A
Authority
IL
Israel
Prior art keywords
chlorospiro
trione
fluorobenzyl
imidazolidine
indoline
Prior art date
Application number
IL71735A
Other languages
English (en)
Other versions
IL71735A0 (en
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Publication of IL71735A0 publication Critical patent/IL71735A0/xx
Publication of IL71735A publication Critical patent/IL71735A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/38Oxygen atoms in positions 2 and 3, e.g. isatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL71735A 1983-05-05 1984-05-02 1'(4-bromo-2-fluorobenzyl),-7'-chlorospiro(imidazolidine-4,3'indoline)-2,2',5-trione and its salts,their preparation and pharmaceutical compositions containing them IL71735A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838312379A GB8312379D0 (en) 1983-05-05 1983-05-05 Heterocyclic compounds

Publications (2)

Publication Number Publication Date
IL71735A0 IL71735A0 (en) 1984-09-30
IL71735A true IL71735A (en) 1987-07-31

Family

ID=10542245

Family Applications (1)

Application Number Title Priority Date Filing Date
IL71735A IL71735A (en) 1983-05-05 1984-05-02 1'(4-bromo-2-fluorobenzyl),-7'-chlorospiro(imidazolidine-4,3'indoline)-2,2',5-trione and its salts,their preparation and pharmaceutical compositions containing them

Country Status (16)

Country Link
US (1) US4581366A (da)
EP (1) EP0125090B1 (da)
JP (1) JPS59206384A (da)
AU (1) AU2773184A (da)
DK (1) DK223484A (da)
ES (1) ES8506715A1 (da)
FI (1) FI841786A (da)
GB (1) GB8312379D0 (da)
GR (1) GR73868B (da)
HU (1) HU191685B (da)
IE (1) IE57356B1 (da)
IL (1) IL71735A (da)
NO (1) NO841778L (da)
NZ (1) NZ208059A (da)
PT (1) PT78527B (da)
ZA (1) ZA843375B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU566869B2 (en) * 1982-05-11 1987-11-05 Imperial Chemical Industries Plc Spiro (imidazolidine-4,3'-indoline) 2,2',5-triones
GB8331194D0 (en) * 1982-12-20 1983-12-29 Ici Plc Chemical process
US5616722A (en) * 1995-12-05 1997-04-01 Mcintyre Group, Ltd. Antimicrobial solution of formaldehyde substituted hydantoin and process for preparation
BRPI0615115A2 (pt) * 2005-08-25 2013-01-01 Colgate Palmolive Co composição e, métodos de umectação da pele, do cabelo, e/ou das unhas e de depósito de uma substáncia a um substrato
US20090076049A1 (en) * 2006-02-07 2009-03-19 Astrazeneca Ab Novel Spiro [Imidazolidine-4, 3' -Indole] 2, 2', 5' (1H) Triones for Treatment of Conditions Associated with Vanilloid Receptor 1

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU532110B2 (en) * 1979-11-13 1983-09-15 Ici Ltd. Spiro(imidazolidine-4,3:-indoline)-2,2:5-trione derivatives

Also Published As

Publication number Publication date
PT78527A (en) 1984-06-01
PT78527B (en) 1986-09-15
AU2773184A (en) 1984-11-08
FI841786A0 (fi) 1984-05-04
US4581366A (en) 1986-04-08
NO841778L (no) 1984-11-06
DK223484D0 (da) 1984-05-04
EP0125090A2 (en) 1984-11-14
IE57356B1 (en) 1992-08-12
IL71735A0 (en) 1984-09-30
ZA843375B (en) 1985-01-30
EP0125090B1 (en) 1990-09-12
ES532215A0 (es) 1985-08-01
GR73868B (da) 1984-05-08
DK223484A (da) 1984-11-06
FI841786A (fi) 1984-11-06
EP0125090A3 (en) 1985-11-27
JPS59206384A (ja) 1984-11-22
IE841112L (en) 1984-11-05
ES8506715A1 (es) 1985-08-01
GB8312379D0 (en) 1983-06-08
HU191685B (en) 1987-03-30
NZ208059A (en) 1987-06-30
HUT34195A (en) 1985-02-28

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