IL65814A0 - Benzazepine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Benzazepine derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL65814A0
Authority: IL; Israel
Prior art keywords: preparation; pharmaceutical compositions; compositions containing; benzazepine derivatives; benzazepine
Prior art date: 1981-05-19

Application number

IL65814A

Other versions

IL65814A (en

Original Assignee

Thomae Gmbh Dr K

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-05-19

Filing date

1982-05-18

Publication date

1982-08-31

1982-05-18 Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K

1982-08-31 Publication of IL65814A0 publication Critical patent/IL65814A0/en

1986-02-28 Publication of IL65814A publication Critical patent/IL65814A/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/04—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Heart & Thoracic Surgery (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Cardiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL65814A 1981-05-19 1982-05-18 3-phenylalkylaminoalkyl-3-benzazepine and 1,3-benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them IL65814A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19813119874 DE3119874A1 (en)	1981-05-19	1981-05-19	"BENZAZEPINE DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS"

Publications (2)

Publication Number	Publication Date
IL65814A0 true IL65814A0 (en)	1982-08-31
IL65814A IL65814A (en)	1986-02-28

Family

ID=6132690

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL65814A IL65814A (en)	1981-05-19	1982-05-18	3-phenylalkylaminoalkyl-3-benzazepine and 1,3-benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (29)

Country	Link
EP (1)	EP0065229B1 (en)
JP (1)	JPS57193462A (en)
KR (3)	KR890001545B1 (en)
AR (1)	AR231130A1 (en)
AT (1)	ATE14725T1 (en)
AU (1)	AU551509B2 (en)
BG (1)	BG60412B2 (en)
CA (1)	CA1185239A (en)
CS (2)	CS251760B2 (en)
DD (1)	DD202872A5 (en)
DE (2)	DE3119874A1 (en)
DK (1)	DK156720C (en)
ES (5)	ES512285A0 (en)
FI (1)	FI77856C (en)
GB (1)	GB2099425B (en)
GR (1)	GR76458B (en)
HK (1)	HK43388A (en)
HU (1)	HU186584B (en)
IE (1)	IE53016B1 (en)
IL (1)	IL65814A (en)
MX (1)	MX9202743A (en)
NO (1)	NO159166C (en)
NZ (1)	NZ200659A (en)
PL (1)	PL136914B1 (en)
PT (1)	PT74919B (en)
SU (1)	SU1160935A3 (en)
UA (1)	UA8038A1 (en)
YU (1)	YU44674B (en)
ZA (1)	ZA823413B (en)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3242599A1 (en) *	1982-11-18	1984-05-24	Dr. Karl Thomae Gmbh, 7950 Biberach	NEW BENZAZEPINE DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS
DE3343801A1 (en) *	1983-12-03	1985-06-13	Dr. Karl Thomae Gmbh, 7950 Biberach	NEW INDOLDER DERIVATIVES, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
DE3418270A1 (en) *	1984-05-17	1985-11-21	Dr. Karl Thomae Gmbh, 7950 Biberach	NEW AMINOTETRAL DERIVATIVES, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
DE3418271A1 (en) *	1984-05-17	1985-11-21	Dr. Karl Thomae Gmbh, 7950 Biberach	NEW BENZAZEPINE DERIVATIVES, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
EP0204349A3 (en) *	1985-06-01	1990-01-03	Dr. Karl Thomae GmbH	Heteroaromatic amine derivatives, medicaments containing them and process for their preparation
DE3717561A1 (en) *	1987-05-25	1988-12-08	Thomae Gmbh Dr K	INDOL, ISOCHINOLINE AND BENZAZEPINE DERIVATIVES, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
DE3541811A1 (en) *	1985-11-27	1987-06-04	Thomae Gmbh Dr K	NEW CYCLIC AMINE DERIVATIVES, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
DE3736866A1 (en) *	1987-10-30	1989-05-11	Thomae Gmbh Dr K	MEANS FOR THE TREATMENT OF HYPERTENSION AND HEART FAILURE
FR2624117B1 (en) *	1987-12-08	1991-02-22	Synthelabo	HYDROXY-3 (METHOXY-4 PHENYL) -2 (METHYLAMINO-2 ETHYL) -5 DIHYDRO-2,3 5H-BENZOTHIAZEPINE-1,5 ONE-4 DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
JP2699511B2 (en) *	1988-01-29	1998-01-19	武田薬品工業株式会社	Substituted amines
JP2807577B2 (en) *	1990-06-15	1998-10-08	エーザイ株式会社	Cyclic amide derivative
FR2681862B1 (en) *	1991-09-27	1993-11-12	Adir Cie	NOVELS (BENZOCYCLOALKYL) ALKYLAMINES, THEIR PREPARATION PROCESS, AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR2705675B1 (en) *	1993-05-27	1996-05-03	Smithkline Beecham Labo Pharma	New compounds, their preparation process and their use as medicaments.
JPH09501405A (en) *	1993-05-27	1997-02-10	スミスクライン・ビーチャム・ラボラトワール・ファルマソーティク	N-substituted 3-benzazepines or isoquinolines for antiarrhythmia
SE9303274D0 (en) *	1993-10-07	1993-10-07	Astra Ab	Novel phenylethyl and phenylproplamines
DE10018401A1 (en)	2000-04-13	2001-10-25	Boehringer Ingelheim Pharma	Medicament for treating hypertrophy-related myocardial disease, containing bradycardic agent, preferably cilobradine, and optionally another cardiac drug
WO2002098865A2 (en)	2001-06-07	2002-12-12	Neuro3D	Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses thereof
US8158814B2 (en) *	2003-08-29	2012-04-17	Mitsui Chemicals, Inc.	Insecticide for agricultural or horticultural use and method of use thereof
FR2868776B1 (en) *	2004-04-13	2008-04-18	Servier Lab	NOVEL PROCESS FOR THE SYNTHESIS OF 1,3-DIHYDRO-2H-3-BENZAZEPIN-2-ONE DERIVATIVES AND THE APPLICATION TO THE SYNTHESIS OF IVABRADINE AND ITS SALTS OF ADDITION TO A PHARMACEUTICALLY ACCEPTABLE ACID
FR2868775B1 (en) *	2004-04-13	2008-04-11	Servier Lab	NOVEL PROCESS FOR THE SYNTHESIS OF 1,3,4,5-TETRAHYDRO-2H-3-BENZAZEPIN-2-ONE DERIVATIVES AND THE APPLICATION TO THE SYNTHESIS OF IVABRADINE AND ITS SALTS OF ADDITION TO A PHARMACEUTICALLY ACCEPTABLE ACID
FR2868777B1 (en) *	2004-04-13	2006-05-26	Servier Lab	NOVEL PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ITS SALTS OF ADDITION TO A PHARMACEUTICALLY ACCEPTABLE ACID
FR2870537A1 (en) *	2004-05-19	2005-11-25	Servier Lab	NOVEL PROCESS FOR SYNTHESIZING (1S) -4,5-DIMETHOXY-1- (METHYL AMINOMETHYL) BENZOCYCLOBUTANE AND ITS ADDITION SALTS AND APPLICATION TO THE SYNTHESIS OF IVABRADINE AND ITS ADDITION SALTS PHARMACEUTICALLY ACCEPTABLE ACID
FR2882553B1 (en) *	2005-02-28	2007-05-04	Servier Lab	CRYSTALLINE BETA FORM OF IVABRADINE HYDROCHLORIDE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
FR2882554B1 (en) *	2005-02-28	2007-05-04	Servier Lab	IVABRADINE HYDROCHLORIDE BETA D-CRYSTALLINE FORM, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
FR2882555B1 (en) *	2005-02-28	2007-05-04	Servier Lab	CRYSTALLINE GAMMA FORM OF IVABRADINE HYDROCHLORIDE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
FR2882556B1 (en) *	2005-02-28	2007-05-04	Servier Lab	CRYSTALLINE GAMMA D FORM OF IVABRADINE HYDROCHLORIDE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
EP1762179A1 (en)	2005-09-07	2007-03-14	Boehringer Ingelheim Vetmedica Gmbh	Method for improving diagnostic quality in echocardiography
FR2891826B1 (en) *	2005-10-11	2007-12-28	Servier Lab	CRYSTALLINE FORM 6 OF IVABRADINE HYDROCHLORIDE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
FR2891827B1 (en) *	2005-10-11	2007-12-28	Servier Lab	CRYSTALLINE DELTAD FORM OF IVABRADINE HYDROCHLORIDE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
FR2920773B1 (en) *	2007-09-11	2009-10-23	Servier Lab	1,2,4,5-TETRAHYDRO-3H-BENZAZEPINES DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2935381B1 (en) *	2008-08-29	2010-12-17	Servier Lab	NOVEL METHOD FOR THE RESOLUTION OF ENANTIOMERES OF (3,4-DIMETHOXY-BICYCLOO-4.2.0-OCTA-1,3,5-TRIEN-7-YL) NITRILE AND APPLICATION TO THE SYNTHESIS OF IVABRADINE
FR2941695B1 (en) *	2009-02-04	2011-02-18	Servier Lab	NOVEL PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ITS SALTS OF ADDITION TO A PHARMACEUTICALLY ACCEPTABLE ACID
FR2943668B1 (en) *	2009-03-31	2011-05-06	Servier Lab	NEW PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ITS SALTS OF ADDITION TO A PHARMACEUTICALLY ACCEPTABLE ACID
FR2943667B1 (en) *	2009-03-31	2011-05-06	Servier Lab	NEW PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ITS SALTS OF ADDITION TO A PHARMACEUTICALLY ACCEPTABLE ACID
FR2956401B1 (en) *	2010-02-17	2012-02-03	Servier Lab	NOVEL PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ITS SALTS OF ADDITION TO A PHARMACEUTICALLY ACCEPTABLE ACID
WO2013024023A1 (en)	2011-08-12	2013-02-21	Boehringer Ingelheim Vetmedica Gmbh	Taste masked pharmaceutical composition
WO2014122248A1 (en)	2013-02-11	2014-08-14	Boehringer Ingelheim Vetmedica Gmbh	Kit-of-parts
FR3003859B1 (en) *	2013-03-26	2015-03-13	Servier Lab	"PROCESS FOR THE SYNTHESIS OF 7,8-DIMETHOXY-1,3-DIHYDRO-2H-3-BENZAZEPIN-2-ONE DERIVATIVES AND APPLICATION TO THE SYNTHESIS OF IVABRADINE"
HU230826B1 (en) *	2014-11-19	2018-07-30	Richter Gedeon Nyrt.	Process for preparation of benzazepine derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3474090A (en) *	1966-12-22	1969-10-21	American Cyanamid Co	3-aminoalkyl-1,3-benzodiazepin-2-ones
US3780023A (en) *	1972-06-30	1973-12-18	J Suh	2-aralkylamino-4,5-dihydro-3h-1,3-benzodiazepines
US4210749A (en) *	1974-11-12	1980-07-01	Pennwalt Corporation	Substituted 1,2,4,5-tetrahydro-3H,3 benzazepines
DE2639718A1 (en)	1976-09-03	1978-03-16	Thomae Gmbh Dr K	NEW PHENYLAETHYLAMINE
ZA786230B (en) *	1977-12-21	1979-10-31	Smithkline Corp	8 and/or 9 substituted 2-benzazepine compounds
ZA792785B (en)	1978-07-07	1980-08-27	Smithkline Corp	Mercapto substituted-2,3,4,5-tetrahydro-1h-3-benzazepines
ES484553A1 (en) *	1978-10-05	1980-05-16	Hoechst Ag	4-Phenyl-1,3-benzodiazepines, method for their preparation, pharmaceutical compositions containing them, and the compounds for use as medicaments.
DE2850078A1 (en) *	1978-11-18	1980-05-29	Basf Ag	AMINOPROPANOL DERIVATIVES OF 6-HYDROXY-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPIN-2-ONS

1981
- 1981-05-19 DE DE19813119874 patent/DE3119874A1/en not_active Withdrawn
1982
- 1982-05-06 EP EP82103931A patent/EP0065229B1/en not_active Expired
- 1982-05-06 AT AT82103931T patent/ATE14725T1/en not_active IP Right Cessation
- 1982-05-06 DE DE8282103931T patent/DE3265206D1/en not_active Expired
- 1982-05-12 CS CS823456A patent/CS251760B2/en unknown
- 1982-05-13 SU SU823435639A patent/SU1160935A3/en active
- 1982-05-13 UA UA3435639A patent/UA8038A1/en unknown
- 1982-05-17 PL PL1982236474A patent/PL136914B1/en unknown
- 1982-05-17 FI FI821724A patent/FI77856C/en not_active IP Right Cessation
- 1982-05-17 DD DD82239912A patent/DD202872A5/en not_active IP Right Cessation
- 1982-05-17 DK DK222382A patent/DK156720C/en not_active IP Right Cessation
- 1982-05-18 ZA ZA823413A patent/ZA823413B/en unknown
- 1982-05-18 AU AU83794/82A patent/AU551509B2/en not_active Expired
- 1982-05-18 CA CA000403172A patent/CA1185239A/en not_active Expired
- 1982-05-18 JP JP57083915A patent/JPS57193462A/en active Granted
- 1982-05-18 AR AR289434A patent/AR231130A1/en active
- 1982-05-18 HU HU821581A patent/HU186584B/en unknown
- 1982-05-18 PT PT74919A patent/PT74919B/en unknown
- 1982-05-18 YU YU1051/82A patent/YU44674B/en unknown
- 1982-05-18 NO NO821645A patent/NO159166C/en not_active IP Right Cessation
- 1982-05-18 ES ES512285A patent/ES512285A0/en active Granted
- 1982-05-18 IL IL65814A patent/IL65814A/en not_active IP Right Cessation
- 1982-05-18 GB GB8214503A patent/GB2099425B/en not_active Expired
- 1982-05-18 IE IE1194/82A patent/IE53016B1/en not_active IP Right Cessation
- 1982-05-18 NZ NZ200659A patent/NZ200659A/en unknown
- 1982-05-19 KR KR1019890001999A patent/KR890001545B1/en not_active IP Right Cessation
- 1982-05-19 GR GR68197A patent/GR76458B/el unknown
- 1982-05-19 KR KR8202240A patent/KR890001544B1/en active
- 1982-11-29 ES ES517757A patent/ES8308311A1/en not_active Expired
- 1982-11-29 ES ES517756A patent/ES8308310A1/en not_active Expired
- 1982-11-29 ES ES517753A patent/ES517753A0/en active Granted
- 1982-11-29 ES ES517758A patent/ES8308312A1/en not_active Expired
1988
- 1988-06-09 HK HK433/88A patent/HK43388A/en not_active IP Right Cessation
1989
- 1989-02-20 KR KR1019890001998A patent/KR890001550B1/en not_active IP Right Cessation
1991
- 1991-12-27 CS CS914102A patent/CS410291A3/en unknown
1992
- 1992-06-09 MX MX9202743A patent/MX9202743A/en unknown
1994
- 1994-01-25 BG BG98418A patent/BG60412B2/en unknown

Also Published As

Publication number	Publication date
GR76458B (en)	1984-08-10
DE3119874A1 (en)	1982-12-09
PT74919A (en)	1982-06-01
IE53016B1 (en)	1988-05-11
HK43388A (en)	1988-06-17
KR830010077A (en)	1983-12-26
BG60412B2 (en)	1995-02-28
DK156720C (en)	1990-02-19
YU44674B (en)	1990-12-31
AR231130A1 (en)	1984-09-28
ES517757A0 (en)	1983-08-16
ES517758A0 (en)	1983-08-16
CS410291A3 (en)	1992-08-12
IL65814A (en)	1986-02-28
YU105182A (en)	1986-12-31
DK222382A (en)	1982-11-20
HU186584B (en)	1985-08-28
PT74919B (en)	1985-05-16
ATE14725T1 (en)	1985-08-15
ZA823413B (en)	1984-01-25
PL136914B1 (en)	1986-04-30
EP0065229A1 (en)	1982-11-24
ES8306726A1 (en)	1983-06-01
ES8308312A1 (en)	1983-08-16
CS251760B2 (en)	1987-08-13
ES517756A0 (en)	1983-08-16
DK156720B (en)	1989-09-25
NO159166C (en)	1988-12-07
ES8308309A1 (en)	1983-08-16
ES512285A0 (en)	1983-06-01
ES8308310A1 (en)	1983-08-16
IE821194L (en)	1982-11-19
FI77856C (en)	1989-05-10
DE3265206D1 (en)	1985-09-12
KR890001544B1 (en)	1989-05-08
ES8308311A1 (en)	1983-08-16
JPS57193462A (en)	1982-11-27
NO159166B (en)	1988-08-29
KR890001545B1 (en)	1989-05-08
FI77856B (en)	1989-01-31
SU1160935A3 (en)	1985-06-07
FI821724A0 (en)	1982-05-17
GB2099425B (en)	1985-02-06
DD202872A5 (en)	1983-10-05
UA8038A1 (en)	1995-12-26
AU8379482A (en)	1982-11-25
NO821645L (en)	1982-11-22
EP0065229B1 (en)	1985-08-07
CA1185239A (en)	1985-04-09
JPH0136829B2 (en)	1989-08-02
PL236474A1 (en)	1983-06-20
NZ200659A (en)	1985-05-31
AU551509B2 (en)	1986-05-01
GB2099425A (en)	1982-12-08
MX9202743A (en)	1992-06-30
ES517753A0 (en)	1983-08-16
KR890001550B1 (en)	1989-05-08

Legal Events

Date	Code	Title	Description
2000-08-31	KB	Patent renewed
2002-07-25	EXP	Patent expired

Publication	Publication Date	Title
IL65814A0 (en)	1982-08-31	Benzazepine derivatives,their preparation and pharmaceutical compositions containing them
IL65257A0 (en)	1983-12-30	Arylcyclo-butanealkylamine derivatives,their preparation and pharmaceutical compositions containing them
IL65803A0 (en)	1982-08-31	Cyclobutene-dione derivatives,their preparation and pharmaceutical compositions containing them
IL66099A0 (en)	1982-09-30	N-aryl-piperazinealkanamides,their preparation and pharmaceutical compositions containing them
IL64777A0 (en)	1982-03-31	3-aminopropoxyaryl derivatives,their preparation and pharmaceutical compositions containing them
IL65076A (en)	1984-12-31	3,4-dihydro-5h-2,3-benzo-diazepine derivatives,their preparation and pharmaceutical compositions containing them
IL70756A (en)	1987-03-31	3-amino-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
IL66408A (en)	1985-12-31	3-amino-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
IL66683A0 (en)	1982-12-31	Benzo-heterocycles,their preparation and pharmaceutical compositions containing them
IL67180A0 (en)	1983-03-31	Morphinate derivatives,their preparation and pharmaceutical compositions containing them
IL65051A0 (en)	1982-04-30	Azepine derivatives,their preparation and pharmaceutical compositions containing them
IL72151A0 (en)	1984-10-31	Tetrahydropyridazinone derivatives,their preparation and pharmaceutical compositions containing them
IL63405A0 (en)	1981-10-30	Benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them
IL65327A0 (en)	1982-05-31	Acylquinolinone derivatives,their preparation and pharmaceutical compositions containing them
IL70755A (en)	1987-03-31	3-amino-4-cyano-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
IL66424A (en)	1985-10-31	3-amino-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
IL75219A0 (en)	1985-09-29	Benzazepine derivatives,their preparation and pharmaceutical compositions containing them
IL63406A0 (en)	1981-10-30	Benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them
IL67155A0 (en)	1983-03-31	Ergoline derivatives,their preparation and pharmaceutical compositions containing them
IL73222A0 (en)	1985-01-31	Benzenesulfonyl-lactam derivatives,their preparation and pharmaceutical compositions containing them
IL66238A0 (en)	1982-11-30	Benzothiazolesulfonamide derivatives,their preparation and pharmaceutical compositions containing them
IL65422A0 (en)	1982-07-30	2-piperazino-pyrimidine derivatives,their preparation and pharmaceutical compositions containing them
IL69845A (en)	1987-09-16	Tetrahydropyran-3 or 4-yl-3-amino-propoxyphenyl derivatives,their preparation and pharmaceutical compositions containing them
IL65177A0 (en)	1982-05-31	Fluoroprostacylins,their preparation and pharmaceutical compositions containing them
IL72757A0 (en)	1984-11-30	Benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them