IL42947A0 - The preparation of benzodiazepine derivatives - Google Patents

The preparation of benzodiazepine derivatives

Info

Publication number
IL42947A0
IL42947A0 IL42947A IL4294773A IL42947A0 IL 42947 A0 IL42947 A0 IL 42947A0 IL 42947 A IL42947 A IL 42947A IL 4294773 A IL4294773 A IL 4294773A IL 42947 A0 IL42947 A0 IL 42947A0
Authority
IL
Israel
Prior art keywords
preparation
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
IL42947A
Other versions
IL42947A (en
Original Assignee
Sparamedica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sparamedica Ag filed Critical Sparamedica Ag
Publication of IL42947A0 publication Critical patent/IL42947A0/en
Publication of IL42947A publication Critical patent/IL42947A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/30Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL42947A 1972-08-21 1973-08-10 Process for the preparation of 1,3-dihydro-2h-1,4-benzodiazepin-2-ones IL42947A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28221772A 1972-08-21 1972-08-21
US35981473A 1973-05-14 1973-05-14

Publications (2)

Publication Number Publication Date
IL42947A0 true IL42947A0 (en) 1973-11-28
IL42947A IL42947A (en) 1977-01-31

Family

ID=26961312

Family Applications (1)

Application Number Title Priority Date Filing Date
IL42947A IL42947A (en) 1972-08-21 1973-08-10 Process for the preparation of 1,3-dihydro-2h-1,4-benzodiazepin-2-ones

Country Status (24)

Country Link
JP (1) JPS5911589B2 (en)
AR (1) AR198108A1 (en)
AT (1) AT341527B (en)
AU (1) AU472777B2 (en)
CA (1) CA1012535A (en)
CH (1) CH578544A5 (en)
DD (1) DD107040A5 (en)
DE (1) DE2340159A1 (en)
DK (1) DK155326C (en)
ES (1) ES418014A1 (en)
FI (1) FI57939C (en)
FR (1) FR2197003B1 (en)
GB (1) GB1392681A (en)
HU (1) HU170153B (en)
IE (1) IE38091B1 (en)
IL (1) IL42947A (en)
LU (1) LU68269A1 (en)
NL (1) NL179582C (en)
NO (1) NO139481C (en)
PH (1) PH13640A (en)
PL (1) PL99162B1 (en)
SE (1) SE408302B (en)
SU (1) SU550980A3 (en)
YU (1) YU219873A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5334792A (en) * 1976-09-13 1978-03-31 Scherico Ltd Production of 1*44 benzodiazepines and 1*44 benzodiazepinee22ones
CN113149915B (en) * 2021-03-01 2024-03-15 中国科学院成都有机化学有限公司 Method for synthesizing clonazepam compound
CN116023342B (en) * 2021-10-26 2024-06-25 江苏昱林生物科技有限公司 Preparation method of high-purity clonazepam

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1136709B (en) * 1959-12-10 1962-09-20 Hoffmann La Roche Process for the preparation of 2-oxo-1, 2-dihydro-1, 4-benzodiazepines
CH537393A (en) * 1969-10-16 1973-05-31 Hoffmann La Roche Process for the preparation of 1,4-benzodiazepine derivatives
BE785962A (en) * 1971-07-08 1973-01-08 Hoffmann La Roche PROCESS FOR THE PREPARATION OF BENZODIAZEPINE DERIVATIVES

Also Published As

Publication number Publication date
FR2197003B1 (en) 1978-01-13
PH13640A (en) 1980-08-18
ATA720773A (en) 1977-06-15
JPS4956992A (en) 1974-06-03
DK155326B (en) 1989-03-28
IE38091L (en) 1974-02-21
JPS5911589B2 (en) 1984-03-16
LU68269A1 (en) 1975-05-21
IL42947A (en) 1977-01-31
DK155326C (en) 1989-08-14
DD107040A5 (en) 1974-07-12
SE408302B (en) 1979-06-05
ES418014A1 (en) 1976-03-16
YU219873A (en) 1982-06-30
NO139481B (en) 1978-12-11
NL7311507A (en) 1974-02-25
AU472777B2 (en) 1976-06-03
FI57939B (en) 1980-07-31
IE38091B1 (en) 1977-12-21
DE2340159A1 (en) 1974-03-07
GB1392681A (en) 1975-04-30
CH578544A5 (en) 1976-08-13
PL99162B1 (en) 1978-06-30
NL179582B (en) 1986-05-01
FR2197003A1 (en) 1974-03-22
NO139481C (en) 1979-03-21
AT341527B (en) 1978-02-10
FI57939C (en) 1980-11-10
SU550980A3 (en) 1977-03-15
NL179582C (en) 1986-10-01
AR198108A1 (en) 1974-05-31
DE2340159C2 (en) 1989-01-19
AU5918073A (en) 1975-02-13
CA1012535A (en) 1977-06-21
HU170153B (en) 1977-04-28

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