IL42196A0 - Anaesthetic steroids - Google Patents

Anaesthetic steroids

Info

Publication number
IL42196A0
IL42196A0 IL42196A IL4219673A IL42196A0 IL 42196 A0 IL42196 A0 IL 42196A0 IL 42196 A IL42196 A IL 42196A IL 4219673 A IL4219673 A IL 4219673A IL 42196 A0 IL42196 A0 IL 42196A0
Authority
IL
Israel
Prior art keywords
anaesthetic
steroids
anaesthetic steroids
Prior art date
Application number
IL42196A
Other versions
IL42196A (en
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of IL42196A0 publication Critical patent/IL42196A0/en
Publication of IL42196A publication Critical patent/IL42196A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0015Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/301,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Steroid Compounds (AREA)
IL42196A 1972-05-05 1973-05-04 Anaesthetic steroids of the pregnane or norpregnane series IL42196A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2114272A GB1430942A (en) 1972-05-05 1972-05-05 21-substituted 3alpha-hydroxy pregnanes

Publications (2)

Publication Number Publication Date
IL42196A0 true IL42196A0 (en) 1973-07-30
IL42196A IL42196A (en) 1978-10-31

Family

ID=10157915

Family Applications (1)

Application Number Title Priority Date Filing Date
IL42196A IL42196A (en) 1972-05-05 1973-05-04 Anaesthetic steroids of the pregnane or norpregnane series

Country Status (16)

Country Link
JP (1) JPS4961150A (en)
AT (1) AT355232B (en)
AU (1) AU475168B2 (en)
BE (1) BE799102A (en)
CA (1) CA1013341A (en)
CH (1) CH617710A5 (en)
DE (1) DE2322532A1 (en)
ES (1) ES414411A1 (en)
FR (1) FR2183792B1 (en)
GB (1) GB1430942A (en)
IE (1) IE37596B1 (en)
IL (1) IL42196A (en)
LU (1) LU67546A1 (en)
NL (1) NL7306234A (en)
SE (1) SE400771B (en)
ZA (1) ZA733035B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
ES2151593T3 (en) * 1994-02-14 2001-01-01 Euro Celtique Sa ANDROSTANS AND PREGNANS FOR ALLOSTERIC MODULATION OF THE GABA RECEIVER.
US5939545A (en) * 1994-02-14 1999-08-17 Cocensys, Inc. Method, compositions, and compounds for allosteric modulation of the gaba receptor by members of the androstane and pregnane series
GR1003861B (en) * 2000-12-29 2002-04-11 Novel gabaa modulating neurosteroids
JP4915427B2 (en) * 2009-03-30 2012-04-11 ブラザー工業株式会社 Liquid supply joint, liquid discharge head and recording apparatus using the same
US20150291654A1 (en) 2011-10-14 2015-10-15 Sage Therapeutics, Inc. 3,3 disubstituted 19-nor pregnane compounds, compositions, and uses thereof
LT2806877T (en) 2012-01-23 2019-12-10 Sage Therapeutics Inc Neuroactive steroid formulations comprising a complex of allopregnanolone and sulfobutyl ether beta-cyclodextrin
HRP20220005T1 (en) 2012-08-21 2022-04-01 Sage Therapeutics, Inc. Allopregnanolone for treating refractory status epilepticus
PT3498725T (en) 2013-04-17 2021-09-09 Sage Therapeutics Inc 19-nor c3,3-disubstituted c21-n-pyrazolyl steroid for use in therapy
SI2986624T1 (en) 2013-04-17 2020-10-30 Sage Therapeutics, Inc. 19-nor neuroactive steroids for methods of treatment
US9725481B2 (en) 2013-04-17 2017-08-08 Sage Therapeutics, Inc. 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof
WO2014169836A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
CA2918735C (en) 2013-07-19 2023-08-01 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
PL3488852T3 (en) 2013-08-23 2021-06-28 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
US10246482B2 (en) 2014-06-18 2019-04-02 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
US20170233433A1 (en) 2014-10-16 2017-08-17 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
RU2020131091A (en) 2014-10-16 2020-11-23 Сейдж Терапьютикс, Инк. COMPOSITIONS AND METHODS FOR TREATMENT OF CNS DISORDERS
HUE049014T2 (en) 2014-11-27 2020-09-28 Sage Therapeutics Inc Compositions and methods for treating cns disorders
EP3250210B1 (en) 2015-01-26 2020-12-02 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
EP3258939B1 (en) 2015-02-20 2022-09-07 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
KR102408399B1 (en) 2016-03-08 2022-06-13 세이지 테라퓨틱스, 인크. Neuroactive steroids, compositions, and uses thereof
IL264129B2 (en) 2016-07-11 2024-05-01 Sage Therapeutics Inc C17, c20, and c21 substituted neuroactive steroids and their methods of use
EP3481844B1 (en) 2016-07-11 2024-04-17 Sage Therapeutics, Inc. C7, c12, and c16 substituted neuroactive steroids and their methods of use
EP3976628A1 (en) 2019-05-31 2022-04-06 Sage Therapeutics, Inc. Neuroactive steroids and compositions thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1346292A (en) * 1962-09-14 1963-12-20 Roussel Uclaf New process for the preparation of 21-amino steroids
US3144446A (en) * 1963-12-20 1964-08-11 Upjohn Co Mono and bis nu-(3alpha, 17alpha-dihydroxy-11, 20-dioxo-5beta-pregnan-21-yl) quaternary ammonium salts of triethylenediamine

Also Published As

Publication number Publication date
LU67546A1 (en) 1973-07-13
IL42196A (en) 1978-10-31
JPS4961150A (en) 1974-06-13
CA1013341A (en) 1977-07-05
ATA395173A (en) 1979-07-15
AT355232B (en) 1980-02-25
ZA733035B (en) 1974-04-24
CH617710A5 (en) 1980-06-13
FR2183792A1 (en) 1973-12-21
IE37596L (en) 1973-11-05
BE799102A (en) 1973-11-05
GB1430942A (en) 1976-04-07
AU475168B2 (en) 1976-08-12
NL7306234A (en) 1973-11-07
IE37596B1 (en) 1977-08-31
DE2322532A1 (en) 1973-11-22
SE400771B (en) 1978-04-10
ES414411A1 (en) 1976-02-01
FR2183792B1 (en) 1977-07-15
AU5528473A (en) 1974-11-07

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