IL41017A - 3-(2-imidazolyl)derivatives of rifamycin - Google Patents

3-(2-imidazolyl)derivatives of rifamycin

Info

Publication number: IL41017A
Authority: IL; Israel
Prior art keywords: rifamycin; derivatives; mono; alkyl; formula
Prior art date: 1972-01-19

Application number

IL41017A

Other languages

English (en)

Other versions

IL41017A0 (en

Original Assignee

Lepetit Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-01-19

Filing date

1972-12-06

Publication date

1976-06-30

1972-12-06 Application filed by Lepetit Spa filed Critical Lepetit Spa

1973-02-28 Publication of IL41017A0 publication Critical patent/IL41017A0/xx

1976-06-30 Publication of IL41017A publication Critical patent/IL41017A/en

Links

HJYYPODYNSCCOU-ODRIEIDWSA-N rifamycin SV Chemical class OC1=C(C(O)=C2C)C3=C(O)C=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O HJYYPODYNSCCOU-ODRIEIDWSA-N 0.000 title abstract 4
-1 carbalkoxy Chemical group 0.000 claims abstract 5
QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 claims abstract 4
125000002837 carbocyclic group Chemical group 0.000 claims abstract 3
150000001875 compounds Chemical class 0.000 claims abstract 3
125000001424 substituent group Chemical group 0.000 claims abstract 3
150000001555 benzenes Chemical class 0.000 claims abstract 2
125000001475 halogen functional group Chemical group 0.000 claims abstract 2
UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims 3
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 2
125000003118 aryl group Chemical group 0.000 claims 2
229910052799 carbon Inorganic materials 0.000 claims 2
125000002883 imidazolyl group Chemical group 0.000 claims 2
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
239000003795 chemical substances by application Substances 0.000 claims 1
150000004985 diamines Chemical class 0.000 claims 1
JEHCHYAKAXDFKV-UHFFFAOYSA-J lead tetraacetate Chemical compound CC(=O)O[Pb](OC(C)=O)(OC(C)=O)OC(C)=O JEHCHYAKAXDFKV-UHFFFAOYSA-J 0.000 claims 1
238000004519 manufacturing process Methods 0.000 claims 1
239000007800 oxidant agent Substances 0.000 claims 1
125000000217 alkyl group Chemical group 0.000 abstract 3
CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 abstract 2
NUJOXMJBOLGQSY-UHFFFAOYSA-N manganese dioxide Chemical compound O=[Mn]=O NUJOXMJBOLGQSY-UHFFFAOYSA-N 0.000 abstract 2
UKWHYYKOEPRTIC-UHFFFAOYSA-N mercury(ii) oxide Chemical compound [Hg]=O UKWHYYKOEPRTIC-UHFFFAOYSA-N 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
RAXXELZNTBOGNW-UHFFFAOYSA-N 1H-imidazole Chemical group C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 1
BBNQHOMJRFAQBN-UPZFVJMDSA-N 3-formylrifamycin sv Chemical compound OC1=C(C(O)=C2C)C3=C(O)C(C=O)=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O BBNQHOMJRFAQBN-UPZFVJMDSA-N 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000005115 alkyl carbamoyl group Chemical group 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
230000001093 anti-cancer Effects 0.000 abstract 1
230000000840 anti-viral effect Effects 0.000 abstract 1
229960005070 ascorbic acid Drugs 0.000 abstract 1
235000010323 ascorbic acid Nutrition 0.000 abstract 1
239000011668 ascorbic acid Substances 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
OWFXIOWLTKNBAP-UHFFFAOYSA-N isoamyl nitrite Chemical compound CC(C)CCON=O OWFXIOWLTKNBAP-UHFFFAOYSA-N 0.000 abstract 1
ACKFDYCQCBEDNU-UHFFFAOYSA-J lead(2+);tetraacetate Chemical compound [Pb+2].CC([O-])=O.CC([O-])=O.CC([O-])=O.CC([O-])=O ACKFDYCQCBEDNU-UHFFFAOYSA-J 0.000 abstract 1
229940101209 mercuric oxide Drugs 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
230000001590 oxidative effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000004151 quinonyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

IL41017A 1972-01-19 1972-12-06 3-(2-imidazolyl)derivatives of rifamycin IL41017A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT1952572		1972-01-19

Publications (2)

Publication Number	Publication Date
IL41017A0 IL41017A0 (en)	1973-02-28
IL41017A true IL41017A (en)	1976-06-30

Family

ID=11158763

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL41017A IL41017A (en)	1972-01-19	1972-12-06	3-(2-imidazolyl)derivatives of rifamycin

Country Status (21)

Country	Link
JP (1)	JPS518959B2 (nl)
AR (1)	AR193313A1 (nl)
AT (1)	AT320855B (nl)
AU (1)	AU466810B2 (nl)
BE (1)	BE794298A (nl)
CA (1)	CA991636A (nl)
CH (1)	CH564554A5 (nl)
DD (1)	DD103236A5 (nl)
DE (1)	DE2301766C3 (nl)
DK (1)	DK135995B (nl)
ES (1)	ES410755A1 (nl)
FR (1)	FR2181676B1 (nl)
GB (1)	GB1388880A (nl)
HU (1)	HU165387B (nl)
IE (1)	IE36939B1 (nl)
IL (1)	IL41017A (nl)
LU (1)	LU66851A1 (nl)
NL (1)	NL159388B (nl)
RO (1)	RO62774A (nl)
SE (1)	SE383152B (nl)
ZA (1)	ZA728306B (nl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5480960U (nl) *	1977-11-18	1979-06-08
US4447432A (en) *	1981-11-17	1984-05-08	Farmitalia Carlo Erba S.P.A.	Azino rifamycins
WO2005070940A2 (en) *	2004-01-13	2005-08-04	Cumbre Pharmaceuticals Inc.	Rifamycin derivatives effective against drug-resistant microbes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1325047A (en) *	1969-08-11	1973-08-01	Ciba Geigy Ag	Rifamycin compounds and processes for their manufacture

0
- BE BE794298D patent/BE794298A/xx unknown
1972
- 1972-11-23 ZA ZA728306A patent/ZA728306B/xx unknown
- 1972-11-30 IE IE1666/72A patent/IE36939B1/xx unknown
- 1972-12-06 IL IL41017A patent/IL41017A/en unknown
- 1972-12-28 GB GB5983272A patent/GB1388880A/en not_active Expired
1973
- 1973-01-15 DE DE2301766A patent/DE2301766C3/de not_active Expired
- 1973-01-15 AU AU51099/73A patent/AU466810B2/en not_active Expired
- 1973-01-15 CH CH52873A patent/CH564554A5/xx not_active IP Right Cessation
- 1973-01-16 DD DD168274A patent/DD103236A5/xx unknown
- 1973-01-16 NL NL7300610.A patent/NL159388B/nl unknown
- 1973-01-16 AR AR246143A patent/AR193313A1/es active
- 1973-01-17 LU LU66851A patent/LU66851A1/xx unknown
- 1973-01-17 AT AT37173A patent/AT320855B/de not_active IP Right Cessation
- 1973-01-18 ES ES410755A patent/ES410755A1/es not_active Expired
- 1973-01-18 FR FR7301784A patent/FR2181676B1/fr not_active Expired
- 1973-01-18 SE SE7300711A patent/SE383152B/xx unknown
- 1973-01-18 CA CA161,561A patent/CA991636A/en not_active Expired
- 1973-01-18 HU HULE675A patent/HU165387B/hu unknown
- 1973-01-18 JP JP48008230A patent/JPS518959B2/ja not_active Expired
- 1973-01-18 DK DK28173AA patent/DK135995B/da unknown
- 1973-01-19 RO RO7300073551A patent/RO62774A/ro unknown

Also Published As

Publication number	Publication date
HU165387B (nl)	1974-08-28
DD103236A5 (nl)	1974-01-12
AR193313A1 (es)	1973-04-11
DE2301766A1 (de)	1973-07-26
IE36939B1 (en)	1977-03-30
FR2181676B1 (nl)	1976-05-14
GB1388880A (en)	1975-03-26
DE2301766C3 (de)	1980-11-20
JPS518959B2 (nl)	1976-03-22
BE794298A (fr)	1973-05-16
JPS4880600A (nl)	1973-10-29
DK135995C (nl)	1978-01-23
SU444372A3 (ru)	1974-09-25
IE36939L (en)	1973-07-19
DE2301766B2 (de)	1980-02-28
AU5109973A (en)	1974-07-18
NL7300610A (nl)	1973-07-23
RO62774A (fr)	1978-02-15
FR2181676A1 (nl)	1973-12-07
SE383152B (sv)	1976-03-01
NL159388B (nl)	1979-02-15
ES410755A1 (es)	1976-01-01
AU466810B2 (en)	1975-11-13
AT320855B (de)	1975-03-10
DK135995B (da)	1977-07-25
CA991636A (en)	1976-06-22
ZA728306B (en)	1973-07-25
IL41017A0 (en)	1973-02-28
LU66851A1 (nl)	1973-03-19
CH564554A5 (nl)	1975-07-31

Publication	Publication Date	Title
GB1489280A (en)	1977-10-19	Indazole derivatives
GB1499115A (en)	1978-01-25	Process for the production of nitro derivatives of aromatic compounds
GB1474631A (en)	1977-05-25	Lactones of the diazaxanthene series and dye precursors for copying processes
ES463803A1 (es)	1978-06-16	Procedimiento para la produccion de hidroxilaminas o-alqui- ladas.
IL41017A (en)	1976-06-30	3-(2-imidazolyl)derivatives of rifamycin
GB1364403A (en)	1974-08-21	1 - aminosulphonyl - 2 - aminobenzimidazoles process for their preparation and their fungicidal use
GB1452545A (en)	1976-10-13	Phenylarylalkyl derivtives and their use as pesticides
GB1395802A (en)	1975-05-29	Substituted benzamides and herbicidal uses thereof
GB1445210A (en)	1976-08-04	Benzothiazole derivatives
ES8403131A1 (es)	1984-03-01	Un procedimiento para la preparacion de derivados de 1,1-dioxido del acido penicilanico.
ES431497A1 (es)	1976-11-01	Procedimiento para preparar un derivado de s-triazol (1,5- a) piridina.
IE870199L (en)	1987-07-27	Heterocyclic compounds and their production.
IE44047L (en)	1977-06-11	Cyanoacetanilide derivatives.
IE43117L (en)	1976-12-16	Naphthacene derivatives
US2520438A (en)	1950-08-29	Bis (4-aminophenyl)-sulfone ascorbate
GB1396203A (en)	1975-06-04	3-phenyl-4-oxo,1,2,3,-triazoline derivatives and their use as herbicides
JPS6111236B2 (nl)	1986-04-01
JPS55108898A (en)	1980-08-21	25-hydroxy-24-oxocholesterol derivative and its preparation
IE40190L (en)	1975-04-25	Penicillin derivatives
JPS54112898A (en)	1979-09-04	Novel preparation of 3-hydrazonomethylrifamycin s and its derivatives
US3595879A (en)	1971-07-27	Naphthoquinone derivatives,preparation thereof and chemotherapeutic compositions therewith and their administration
JPS55143990A (en)	1980-11-10	Preparation of novel diamine derivative, and thienodiazepin-2-one derivative containing the same
JPS5735584A (en)	1982-02-26	N-(substituted chromone-3-carbonyl)phenylglycine derivative
GB1331059A (en)	1973-09-19	Pyrimidotriazinone compounds
ES445301A1 (es)	1977-06-01	Un procedimiento para la preparacion de nuevos derivados de xantina.