IL289399B2 - Neurosleeve for closed loop emg-fes based control of pathological tremors - Google Patents

Neurosleeve for closed loop emg-fes based control of pathological tremors

Info

Publication number
IL289399B2
IL289399B2 IL289399A IL28939921A IL289399B2 IL 289399 B2 IL289399 B2 IL 289399B2 IL 289399 A IL289399 A IL 289399A IL 28939921 A IL28939921 A IL 28939921A IL 289399 B2 IL289399 B2 IL 289399B2
Authority
IL
Israel
Prior art keywords
tremor
nmes
tremors
suppressing
anatomical
Prior art date
Application number
IL289399A
Other languages
Hebrew (he)
Other versions
IL289399A (en
IL289399B (en
Inventor
Sharma Gaurav
Ganzer Patrick
Original Assignee
Battelle Memorial Institute
Sharma Gaurav
Ganzer Patrick
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2020/039802 external-priority patent/WO2020264280A1/en
Application filed by Battelle Memorial Institute, Sharma Gaurav, Ganzer Patrick filed Critical Battelle Memorial Institute
Publication of IL289399A publication Critical patent/IL289399A/en
Publication of IL289399B publication Critical patent/IL289399B/en
Publication of IL289399B2 publication Critical patent/IL289399B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0452—Specially adapted for transcutaneous muscle stimulation [TMS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/296—Bioelectric electrodes therefor specially adapted for particular uses for electromyography [EMG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0456—Specially adapted for transcutaneous electrical nerve stimulation [TENS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0476—Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0484—Garment electrodes worn by the patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36003—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of motor muscles, e.g. for walking assistance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A61N1/36031—Control systems using physiological parameters for adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36067—Movement disorders, e.g. tremor or Parkinson disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physiology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Electrotherapy Devices (AREA)
  • Prostheses (AREA)
  • Eye Examination Apparatus (AREA)
  • Magnetic Treatment Devices (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Description

289399/2

Claims (6)

289399/2 The invention claimed is:
1. A tremor suppression device comprising: a garment wearable on an anatomical region and including electrodes contacting the anatomical region when the garment is worn on the anatomical region; and an electronic controller configured to: detect electromyography (EMG) signals as a function of anatomical location and time using the electrodes; identify tremors as a function of anatomical location and time based on the EMG signals; determine tremor suppressing neuromuscular electrical stimulation (NMES) at one or more anatomical locations as a function of time based on the identified tremors and an anatomy-specific tremor migration model; and apply the determined tremor suppressing NMES using the electrodes to suppress the identified tremors.
2. The tremor suppression device of claim 1, wherein the electronic processor is configured to identify tremors by operations including spectral filtering the EMG signals to remove frequency components corresponding to voluntary motion.
3. The tremor suppression device of claim 1, wherein the determining of the tremor suppressing NMES is further based on the applied tremor suppressing NMES creating a feedback loop to adjust the applied tremor suppressing NMES. 12 289399/2
4. A tremor suppression device comprising: a garment wearable on an anatomical region and including electrodes contacting the anatomical region when the garment is worn on the anatomical region; and an electronic controller configured to: detect electromyography (EMG) signals as a function of anatomical location and time using the electrodes; identify tremors as a function of anatomical location and time based on the EMG signals; determine a tremor migration rate and direction based on a rate of change in anatomical location of the identified tremors as a function of time; determine tremor suppressing neuromuscular electrical stimulation (NMES) at one or more anatomical locations as a function of time based on the identified tremors and the determined tremor migration rate and direction; and apply the determined tremor suppressing NMES using the electrodes to suppress the identified tremors.
5. The tremor suppression device of claim 4, wherein the electronic processor is configured to identify tremors by operations including spectral filtering the EMG signals to remove frequency components corresponding to voluntary motion.
6. The tremor suppression device of claim 4, wherein the determining of the tremor suppressing NMES is further based on the applied tremor suppressing NMES creating a feedback loop to adjust the applied tremor suppressing NMES. 13
IL289399A 2019-06-28 2021-12-26 Neurosleeve for closed loop emg-fes based control of pathological tremors IL289399B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962868158P 2019-06-28 2019-06-28
PCT/US2020/039802 WO2020264280A1 (en) 2019-06-28 2020-06-26 Neurosleeve for closed loop emg-fes based control of pathological tremors

Publications (3)

Publication Number Publication Date
IL289399A IL289399A (en) 2022-02-01
IL289399B IL289399B (en) 2022-10-01
IL289399B2 true IL289399B2 (en) 2023-02-01

Family

ID=74044233

Family Applications (2)

Application Number Title Priority Date Filing Date
IL291105A IL291105B1 (en) 2019-06-28 2020-06-26 Neurosleeve for closed loop emg-fes based control of pathological tremors
IL289399A IL289399B2 (en) 2019-06-28 2021-12-26 Neurosleeve for closed loop emg-fes based control of pathological tremors

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL291105A IL291105B1 (en) 2019-06-28 2020-06-26 Neurosleeve for closed loop emg-fes based control of pathological tremors

Country Status (5)

Country Link
US (3) US11160971B2 (en)
EP (1) EP3990098A1 (en)
BR (1) BR112021026669A2 (en)
CA (1) CA3144964A1 (en)
IL (2) IL291105B1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3352843B1 (en) 2015-09-23 2021-06-23 Cala Health, Inc. Device for peripheral nerve stimulation in the finger to treat hand tremors
IL286747B2 (en) 2016-01-21 2024-05-01 Cala Health Inc Wearable device for treating urinary symptoms
EP3740274A4 (en) 2018-01-17 2021-10-27 Cala Health, Inc. Systems and methods for treating inflammatory bowel disease through peripheral nerve stimulation
US11701293B2 (en) 2018-09-11 2023-07-18 Encora, Inc. Apparatus and method for reduction of neurological movement disorder symptoms using wearable device
BR112021026669A2 (en) * 2019-06-28 2022-02-15 Battelle Memorial Institute Neurosleeve for closed-loop emg-fes-based control of pathological tremors
US11766191B2 (en) * 2019-06-28 2023-09-26 Battelle Memorial Institute Neurosleeve for closed loop EMG-FES based control of pathological tremors
US11890468B1 (en) 2019-10-03 2024-02-06 Cala Health, Inc. Neurostimulation systems with event pattern detection and classification

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8112155B2 (en) 2004-02-05 2012-02-07 Motorika Limited Neuromuscular stimulation
US7643882B2 (en) 2005-05-24 2010-01-05 Leon Boston Tremor reduction systems suitable for self-application and use in disabled patients
US20070012395A1 (en) 2005-07-15 2007-01-18 Tuertscher Jennifer L Methods involving processing of a continuous web at a desired location in relationship to the actual location of a discrete part
US20100174342A1 (en) 2006-11-26 2010-07-08 Leon Boston Tremor reduction systems suitable for self-application and use in disabled patients
WO2009051638A1 (en) 2007-10-16 2009-04-23 Medtronic, Inc. Therapy control based on a patient movement state
US9884178B2 (en) * 2012-12-05 2018-02-06 Battelle Memorial Institute Neuromuscular stimulation cuff
US9884179B2 (en) 2012-12-05 2018-02-06 Bbattelle Memorial Institute Neural sleeve for neuromuscular stimulation, sensing and recording
ES2889752T3 (en) 2013-01-21 2022-01-13 Cala Health Inc Devices and methods to control tremors
EP4108292A1 (en) 2013-05-08 2022-12-28 Consejo Superior De Investigaciones Científicas (CSIC) Method and neuroprosthetic device for monitoring and suppression of pathological tremors through neurostimulation of the afferent pathways
US10437335B2 (en) 2015-04-14 2019-10-08 John James Daniels Wearable electronic, multi-sensory, human/machine, human/human interfaces
WO2018098046A2 (en) 2016-11-25 2018-05-31 Kinaptic, LLC Haptic human machine interface and wearable electronics methods and apparatus
US11058352B2 (en) 2017-11-16 2021-07-13 Klick Inc. Electrical stimulation facilitated symptom transference for empathic response
WO2019126080A1 (en) 2017-12-18 2019-06-27 Dan Sachs Devices, systems and methods for therapeutic muscle stimulation
BR112021026669A2 (en) * 2019-06-28 2022-02-15 Battelle Memorial Institute Neurosleeve for closed-loop emg-fes-based control of pathological tremors
US11766191B2 (en) * 2019-06-28 2023-09-26 Battelle Memorial Institute Neurosleeve for closed loop EMG-FES based control of pathological tremors

Also Published As

Publication number Publication date
US11642513B2 (en) 2023-05-09
CA3144964A1 (en) 2020-12-30
US11911604B2 (en) 2024-02-27
IL289399A (en) 2022-02-01
US20220001164A1 (en) 2022-01-06
BR112021026669A2 (en) 2022-02-15
IL291105B1 (en) 2024-05-01
IL291105A (en) 2022-05-01
US20230233843A1 (en) 2023-07-27
EP3990098A1 (en) 2022-05-04
US11160971B2 (en) 2021-11-02
IL289399B (en) 2022-10-01
US20200406022A1 (en) 2020-12-31

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