IL177173A0 - New crystalline form v of agomelatine, a process for its preparation and pharmaceutical compositions containing it - Google Patents

New crystalline form v of agomelatine, a process for its preparation and pharmaceutical compositions containing it

Info

Publication number: IL177173A0
Authority: IL; Israel
Prior art keywords: agomelatine; preparation; pharmaceutical compositions; crystalline form; compositions containing
Prior art date: 2005-08-03

Application number

IL177173A

Other versions

IL177173A (en

Original Assignee

Servier Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-08-03

Filing date

2006-07-31

Publication date

2006-12-10

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36581629&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL177173(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2006-07-31 Application filed by Servier Lab filed Critical Servier Lab

2006-12-10 Publication of IL177173A0 publication Critical patent/IL177173A0/en

2011-10-31 Publication of IL177173A publication Critical patent/IL177173A/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C07C231/24—Separation; Purification
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Pain & Pain Management (AREA)
Obesity (AREA)
Immunology (AREA)
Hematology (AREA)
Gynecology & Obstetrics (AREA)
Psychiatry (AREA)
Emergency Medicine (AREA)
Anesthesiology (AREA)
Psychology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Child & Adolescent Psychology (AREA)
Hospice & Palliative Care (AREA)
Pregnancy & Childbirth (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicinal Preparation (AREA)
Steroid Compounds (AREA)

IL177173A 2005-08-03 2006-07-31 Crystalline form v of agomelatine, process for its preparation using high energy grinder and pharmaceutical compositions containing it IL177173A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0508278A FR2889523B1 (en)	2005-08-03	2005-08-03	NOVEL CRYSTALLINE FORM V OF AGOMELATIN, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

Publications (2)

Publication Number	Publication Date
IL177173A0 true IL177173A0 (en)	2006-12-10
IL177173A IL177173A (en)	2011-10-31

Family

ID=36581629

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL177173A IL177173A (en)	2005-08-03	2006-07-31	Crystalline form v of agomelatine, process for its preparation using high energy grinder and pharmaceutical compositions containing it

Country Status (38)

Country	Link
EP (2)	EP1752443B1 (en)
JP (1)	JP4575337B2 (en)
CN (1)	CN100448843C (en)
AP (1)	AP2486A (en)
AR (1)	AR057715A1 (en)
AU (1)	AU2006203342B2 (en)
BR (1)	BRPI0603059A (en)
CA (1)	CA2555115C (en)
CR (1)	CR8529A (en)
CU (1)	CU20060153A7 (en)
CY (1)	CY1113011T1 (en)
DK (1)	DK1752443T3 (en)
EA (1)	EA011030B1 (en)
EC (1)	ECSP066715A (en)
ES (1)	ES2391406T3 (en)
FR (1)	FR2889523B1 (en)
GT (1)	GT200600346A (en)
HK (1)	HK1098128A1 (en)
HR (1)	HRP20120779T1 (en)
IL (1)	IL177173A (en)
JO (1)	JO2793B1 (en)
MA (1)	MA28451B1 (en)
ME (1)	ME02026B (en)
MX (1)	MXPA06008789A (en)
MY (1)	MY139902A (en)
NO (1)	NO336967B1 (en)
NZ (1)	NZ548864A (en)
PE (1)	PE20070365A1 (en)
PL (1)	PL1752443T3 (en)
PT (1)	PT1752443E (en)
RS (1)	RS52423B (en)
SA (1)	SA06270255B1 (en)
SG (1)	SG130110A1 (en)
SI (1)	SI1752443T1 (en)
TW (1)	TWI359128B (en)
UA (1)	UA83720C2 (en)
WO (1)	WO2007015004A2 (en)
ZA (1)	ZA200606453B (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2934856B1 (en) *	2008-08-05	2010-08-13	Servier Lab	NEW PROCESS FOR OBTAINING THE V-CRYSTALLINE FORM OF AGOMELATIN
CN101481321B (en) *	2009-02-27	2012-04-18	上海医药工业研究院	Agomelatine halogen hydride complex and preparation thereof
CN101585779B (en) *	2009-03-10	2014-04-02	上海医药工业研究院	New crystal form of Agomelatine, preparation method and use thereof
WO2011006387A1 (en) *	2009-07-11	2011-01-20	浙江华海药业股份有限公司	Process for preparing agomelatine, crystals of agomelatine and preparing process thereof
CN102001959B (en) *	2009-09-01	2014-07-02	北京本草天源药物研究院	Medicinal crystal as well as preparation method and application thereof
CN102050755B (en) *	2009-10-29	2014-11-05	重庆医药工业研究院有限责任公司	Novel agomelatine crystal forms and preparation methods of agomelatine crystal forms
CN101781226B (en) *	2009-12-23	2012-03-28	天津泰普药品科技发展有限公司	Agomelatine and medicine composition thereof
EP2580183B1 (en)	2010-06-10	2014-07-23	Gador S.A.	New process for the preparation of n-[2-(7-methoxy-1-naphthyl)-ethyl]acetamide
CN102000583B (en) *	2010-11-18	2012-08-15	烟台万华聚氨酯股份有限公司	Catalyst for preparing chlorine by oxidizing hydrogen chloride and preparation method thereof
CN102690210A (en) *	2011-03-23	2012-09-26	上海医药工业研究院	Novel crystal form VII of agomelatine, preparation method and application thereof and pharmaceutical composition containing the same
CN102690209A (en) *	2011-03-23	2012-09-26	上海医药工业研究院	Mixed crystal of agomelatine (form-VIII), preparation method and application thereof and pharmaceutical composition containing the same
PT2723714T (en) *	2011-06-02	2017-08-18	Chinoin Zrt	Novel processes for the preparation of prostaglandin amides
FR2978916B1 (en)	2011-08-10	2013-07-26	Servier Lab	SOLID PHARMACEUTICAL COMPOSITION FOR BUCCAL ADMINISTRATION OF AGOMELATIN
WO2013082302A1 (en)	2011-11-30	2013-06-06	Ratiopharm Gmbh	Agomelatine-urea complex and crystalline forms thereof
CZ2012108A3 (en)	2012-02-15	2013-02-27	Zentiva Ks	A method for the manufacture of a polymorphously stable pharmaceutical composition containing agomelatine
CN103360275B (en) *	2012-03-30	2015-04-22	上海创诺制药有限公司	Method for preparing agomelatine I-type crystal
WO2014096373A1 (en)	2012-12-21	2014-06-26	Laboratorios Lesvi, S. L.	Process for prepararing n-(2-(7-methoxy-1-naphthalenyl)ethyl) acetamide and solid forms thereof
FR3001894A1 (en)	2013-02-08	2014-08-15	Servier Lab	SOLID PHARMACEUTICAL COMPOSITION FOR BUCCAL ADMINISTRATION OF AGOMELATIN
EP2810647A1 (en)	2013-06-06	2014-12-10	Zentiva, a.s.	Pharmaceutical formulations comprising agomelatine in the form of agomelatine co-crystal with an organic acid
EP2810656B1 (en)	2013-06-06	2017-08-02	Zentiva, a.s.	Agomelatine formulations comprising agomelatine in the form of co-crystals
CZ2013621A3 (en)	2013-08-13	2015-02-25	Zentiva, K.S.	Agomelatine thermodynamically stable congealed solution for use in pharmaceutical formulation
WO2015124496A1 (en)	2014-02-19	2015-08-27	Synthon B.V.	Pharmaceutical composition comprising amorphous agomelatine
FR3033131B1 (en)	2015-02-26	2017-11-17	Servitronique	SLIDE FOR ITS SLIDING ADJUSTMENT SYSTEMS AND ASSEMBLY METHOD
ES2959460T3 (en)	2015-03-31	2024-02-26	Fis Fabbrica Italiana Sintetici Spa	solid form of agomelatine
EP3466923A1 (en)	2017-10-09	2019-04-10	KRKA, d.d., Novo mesto	Process for the preparation of agomelatine in crystalline form
EP3466413A1 (en)	2017-10-09	2019-04-10	KRKA, d.d., Novo mesto	Pharmaceutical composition containing agomelatine and process for the preparation thereof
CN113952323A (en) *	2021-12-10	2022-01-21	李甜	Application of agomelatine in inhibition of Ube2c protein expression

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2658818B1 (en) *	1990-02-27	1993-12-31	Adir Cie	NOVEL DERIVATIVES WITH NAPHTHALENIC STRUCTURE, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR2866336B1 (en) *	2004-02-13	2006-03-24	Servier Lab	NOVEL PROCESS FOR THE SYNTHESIS OF (7-METHOXY-3,4-DIHYDRO-1-NAPHTHALENYL) ACETONITRILE AND APPLICATION TO THE SYNTHESIS OF AGOMELATIN
FR2866335B1 (en) *	2004-02-13	2006-05-26	Servier Lab	NEW PROCESS FOR THE SYNTHESIS OF AGOMELATIN

2005
- 2005-08-03 FR FR0508278A patent/FR2889523B1/en not_active Expired - Fee Related
2006
- 2006-07-19 PE PE2006000868A patent/PE20070365A1/en not_active Application Discontinuation
- 2006-07-20 EC EC2006006715A patent/ECSP066715A/es unknown
- 2006-07-24 AP AP2006003695A patent/AP2486A/en active
- 2006-07-24 JO JO2006247A patent/JO2793B1/en active
- 2006-07-24 CR CR8529A patent/CR8529A/en unknown
- 2006-07-24 MA MA29212A patent/MA28451B1/en unknown
- 2006-07-31 GT GT200600346A patent/GT200600346A/en unknown
- 2006-07-31 IL IL177173A patent/IL177173A/en active IP Right Grant
- 2006-08-01 SA SA06270255A patent/SA06270255B1/en unknown
- 2006-08-01 NZ NZ548864A patent/NZ548864A/en not_active IP Right Cessation
- 2006-08-01 SG SG200605171-8A patent/SG130110A1/en unknown
- 2006-08-02 PT PT06291251T patent/PT1752443E/en unknown
- 2006-08-02 DK DK06291251.4T patent/DK1752443T3/en active
- 2006-08-02 PL PL06291251T patent/PL1752443T3/en unknown
- 2006-08-02 ME MEP-2012-327A patent/ME02026B/en unknown
- 2006-08-02 NO NO20063517A patent/NO336967B1/en unknown
- 2006-08-02 EA EA200601273A patent/EA011030B1/en unknown
- 2006-08-02 CU CU20060153A patent/CU20060153A7/en unknown
- 2006-08-02 TW TW095128302A patent/TWI359128B/en not_active IP Right Cessation
- 2006-08-02 EP EP06291251A patent/EP1752443B1/en active Active
- 2006-08-02 BR BRPI0603059-9A patent/BRPI0603059A/en not_active Application Discontinuation
- 2006-08-02 EP EP10011469A patent/EP2277857A3/en not_active Withdrawn
- 2006-08-02 RS RS20120327A patent/RS52423B/en unknown
- 2006-08-02 SI SI200631396T patent/SI1752443T1/en unknown
- 2006-08-02 AR ARP060103366A patent/AR057715A1/en not_active Application Discontinuation
- 2006-08-02 WO PCT/FR2006/001869 patent/WO2007015004A2/en active Application Filing
- 2006-08-02 ES ES06291251T patent/ES2391406T3/en active Active
- 2006-08-02 MY MYPI20063736A patent/MY139902A/en unknown
- 2006-08-02 UA UAA200608689A patent/UA83720C2/en unknown
- 2006-08-03 CN CNB2006101083952A patent/CN100448843C/en active Active
- 2006-08-03 CA CA2555115A patent/CA2555115C/en active Active
- 2006-08-03 JP JP2006211622A patent/JP4575337B2/en not_active Expired - Fee Related
- 2006-08-03 MX MXPA06008789A patent/MXPA06008789A/en active IP Right Grant
- 2006-08-03 ZA ZA200606453A patent/ZA200606453B/en unknown
- 2006-08-03 AU AU2006203342A patent/AU2006203342B2/en not_active Ceased
2007
- 2007-04-30 HK HK07104583.8A patent/HK1098128A1/en not_active IP Right Cessation
2012
- 2012-07-18 CY CY20121100635T patent/CY1113011T1/en unknown
- 2012-10-01 HR HRP20120779TT patent/HRP20120779T1/en unknown

Also Published As

Publication number	Publication date
WO2007015004A2 (en)	2007-02-08
JO2793B1 (en)	2014-03-15
WO2007015004A3 (en)	2007-03-22
SI1752443T1 (en)	2012-10-30
AP2006003695A0 (en)	2006-08-31
AU2006203342A1 (en)	2007-02-22
EP2277857A2 (en)	2011-01-26
JP2007056017A (en)	2007-03-08
HRP20120779T1 (en)	2012-10-31
ME02026B (en)	2012-11-06
GT200600346A (en)	2007-02-28
AR057715A1 (en)	2007-12-12
NO336967B1 (en)	2015-12-07
CR8529A (en)	2006-12-07
ES2391406T3 (en)	2012-11-26
MXPA06008789A (en)	2007-02-02
HK1098128A1 (en)	2007-07-13
CU20060153A7 (en)	2012-04-15
NO20063517L (en)	2007-02-05
PE20070365A1 (en)	2007-06-02
JP4575337B2 (en)	2010-11-04
NZ548864A (en)	2008-03-28
SA06270255B1 (en)	2010-06-13
CN100448843C (en)	2009-01-07
EA011030B1 (en)	2008-12-30
CY1113011T1 (en)	2016-04-13
MA28451B1 (en)	2007-03-01
EP1752443A1 (en)	2007-02-14
EP1752443B1 (en)	2012-07-11
EP2277857A3 (en)	2011-06-01
BRPI0603059A (en)	2007-08-14
CN1907958A (en)	2007-02-07
TW200736199A (en)	2007-10-01
RS52423B (en)	2013-02-28
AU2006203342B2 (en)	2012-07-19
FR2889523A1 (en)	2007-02-09
SG130110A1 (en)	2007-03-20
FR2889523B1 (en)	2007-12-28
CA2555115A1 (en)	2007-02-03
AP2486A (en)	2012-10-03
DK1752443T3 (en)	2012-10-22
UA83720C2 (en)	2008-08-11
ZA200606453B (en)	2007-12-27
ECSP066715A (en)	2007-03-29
PL1752443T3 (en)	2012-11-30
CA2555115C (en)	2013-12-10
EA200601273A1 (en)	2007-02-27
MY139902A (en)	2009-11-30
TWI359128B (en)	2012-03-01
IL177173A (en)	2011-10-31
PT1752443E (en)	2012-07-25

Legal Events

Date	Code	Title
2012-02-29	FF	Patent granted
2012-03-29	KB	Patent renewed
2012-07-31	KB	Patent renewed
2020-07-30	KB	Patent renewed

Publication	Publication Date	Title
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SI1695709T1 (en)	2008-10-31	Crystalline form gamma-d of the chlorohydrate of ivabradine, process for its preparation and pharmaceutical compositions containing it
ZA200601762B (en)	2007-04-25	ß-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
IL187359A (en)	2013-04-30	Crystalline form i of tigecycline, composition comprising it, a process for its preparation and use thereof to prepare a pharmaceutical composition for parenteral use