IL171031A - 2-chloromethyl- 6- methylbenzoic acid esters and a process for their preparation - Google Patents

2-chloromethyl- 6- methylbenzoic acid esters and a process for their preparation

Info

Publication number
IL171031A
IL171031A IL171031A IL17103105A IL171031A IL 171031 A IL171031 A IL 171031A IL 171031 A IL171031 A IL 171031A IL 17103105 A IL17103105 A IL 17103105A IL 171031 A IL171031 A IL 171031A
Authority
IL
Israel
Prior art keywords
chloromethyl
preparation
acid esters
methylbenzoic acid
methylbenzoic
Prior art date
Application number
IL171031A
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of IL171031A publication Critical patent/IL171031A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/307Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL171031A 2003-03-25 2005-09-21 2-chloromethyl- 6- methylbenzoic acid esters and a process for their preparation IL171031A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10313228A DE10313228A1 (en) 2003-03-25 2003-03-25 Synthesis of 2-chloromethyl-6-methylbenzoic acid esters
PCT/EP2004/002579 WO2004085377A1 (en) 2003-03-25 2004-03-12 Synthesis of 2-chloromethyl-6-methylbenzoic acid esters

Publications (1)

Publication Number Publication Date
IL171031A true IL171031A (en) 2010-11-30

Family

ID=33015963

Family Applications (1)

Application Number Title Priority Date Filing Date
IL171031A IL171031A (en) 2003-03-25 2005-09-21 2-chloromethyl- 6- methylbenzoic acid esters and a process for their preparation

Country Status (25)

Country Link
EP (1) EP1611083B1 (en)
JP (1) JP4510805B2 (en)
KR (1) KR20050116388A (en)
CN (1) CN100378065C (en)
AR (1) AR043752A1 (en)
AT (1) ATE374742T1 (en)
AU (1) AU2004224177B2 (en)
BR (1) BRPI0408653A (en)
CA (1) CA2519715A1 (en)
CO (1) CO5690546A2 (en)
CY (1) CY1107029T1 (en)
DE (2) DE10313228A1 (en)
DK (1) DK1611083T3 (en)
ES (1) ES2293237T3 (en)
HK (1) HK1087098A1 (en)
IL (1) IL171031A (en)
MX (1) MXPA05010001A (en)
NO (1) NO20054875L (en)
NZ (1) NZ542603A (en)
PL (1) PL1611083T3 (en)
PT (1) PT1611083E (en)
RU (1) RU2345982C2 (en)
TW (1) TW200502213A (en)
WO (1) WO2004085377A1 (en)
ZA (1) ZA200506499B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005029382B3 (en) 2005-06-24 2006-12-21 Sanofi-Aventis Deutschland Gmbh New alkoxymethylyl substituted benzoic acid derivatives are peroxisome proliferation activated receptor agonists used for treating and/or preventing e.g. diabetes mellitus, dyslipidemia and disturbances in fatty acid metabolism
CN114805120A (en) * 2022-05-23 2022-07-29 江苏瑞达环保科技有限公司 Synthesis process of m-cyanomethyl benzoate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4689425A (en) * 1986-11-06 1987-08-25 Stauffer Chemical Company Photochlorination of aromatic compounds in the side chain
ES2287016T3 (en) * 1999-04-28 2007-12-16 Sanofi-Aventis Deutschland Gmbh DERIVATIVES OF DIARIL-ACID AS LIGANDS OF THE PPAR RECEIVER.
IL145923A0 (en) * 1999-04-28 2002-07-25 Aventis Pharma Gmbh Tri-aryl acid derivatives as ppar receptor ligands
CA2458210C (en) * 2001-08-31 2011-09-20 Aventis Pharma Deutschland Gmbh Diaryl cycloalkyl derivatives, method for producing the same and the use thereof as ppar-activators

Also Published As

Publication number Publication date
WO2004085377A1 (en) 2004-10-07
ES2293237T3 (en) 2008-03-16
NO20054875L (en) 2005-12-27
CN1759092A (en) 2006-04-12
CA2519715A1 (en) 2004-10-07
KR20050116388A (en) 2005-12-12
HK1087098A1 (en) 2006-10-06
ZA200506499B (en) 2006-07-26
AU2004224177B2 (en) 2010-01-21
NZ542603A (en) 2007-12-21
JP2006521307A (en) 2006-09-21
EP1611083B1 (en) 2007-10-03
DE502004005137D1 (en) 2007-11-15
NO20054875D0 (en) 2005-10-21
AR043752A1 (en) 2005-08-10
AU2004224177A1 (en) 2004-10-07
CY1107029T1 (en) 2012-09-26
RU2005132827A (en) 2006-02-10
DE10313228A1 (en) 2004-10-21
TW200502213A (en) 2005-01-16
EP1611083A1 (en) 2006-01-04
ATE374742T1 (en) 2007-10-15
DK1611083T3 (en) 2008-01-21
JP4510805B2 (en) 2010-07-28
PL1611083T3 (en) 2008-01-31
CO5690546A2 (en) 2006-10-31
CN100378065C (en) 2008-04-02
BRPI0408653A (en) 2006-03-07
RU2345982C2 (en) 2009-02-10
MXPA05010001A (en) 2005-11-17
PT1611083E (en) 2007-11-26

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Legal Events

Date Code Title Description
MM9K Patent not in force due to non-payment of renewal fees