IL160018A0 - Isoxazolopyridinones and use thereof in the treatment of parkinson's disease - Google Patents

Isoxazolopyridinones and use thereof in the treatment of parkinson's disease

Info

Publication number
IL160018A0
IL160018A0 IL16001802A IL16001802A IL160018A0 IL 160018 A0 IL160018 A0 IL 160018A0 IL 16001802 A IL16001802 A IL 16001802A IL 16001802 A IL16001802 A IL 16001802A IL 160018 A0 IL160018 A0 IL 160018A0
Authority
IL
Israel
Prior art keywords
isoxazolopyridinones
parkinson
disease
treatment
Prior art date
Application number
IL16001802A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL160018A0 publication Critical patent/IL160018A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL16001802A 2001-08-15 2002-08-14 Isoxazolopyridinones and use thereof in the treatment of parkinson's disease IL160018A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0119911.6A GB0119911D0 (en) 2001-08-15 2001-08-15 Organic Compounds
PCT/EP2002/009134 WO2003015780A2 (en) 2001-08-15 2002-08-14 Isoxazolopyridinones and use thereof in the treatment of parkinson's disease

Publications (1)

Publication Number Publication Date
IL160018A0 true IL160018A0 (en) 2004-06-20

Family

ID=9920454

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16001802A IL160018A0 (en) 2001-08-15 2002-08-14 Isoxazolopyridinones and use thereof in the treatment of parkinson's disease

Country Status (24)

Country Link
US (1) US7087756B2 (es)
EP (1) EP1418912B1 (es)
JP (1) JP2005501847A (es)
KR (1) KR20040029429A (es)
CN (1) CN100384418C (es)
AR (1) AR036351A1 (es)
AT (1) ATE355059T1 (es)
BR (1) BR0211903A (es)
CA (1) CA2454762A1 (es)
CO (1) CO5560566A2 (es)
DE (1) DE60218484T2 (es)
EC (1) ECSP044971A (es)
ES (1) ES2282467T3 (es)
GB (1) GB0119911D0 (es)
HU (1) HUP0401325A3 (es)
IL (1) IL160018A0 (es)
MX (1) MXPA04001419A (es)
NO (1) NO20040659D0 (es)
PE (1) PE20030356A1 (es)
PL (1) PL366848A1 (es)
PT (1) PT1418912E (es)
RU (1) RU2004107847A (es)
WO (1) WO2003015780A2 (es)
ZA (1) ZA200400525B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2451057A1 (en) * 2001-06-14 2002-12-27 Banyu Pharmaceutical Co., Ltd. Novel isoxazolopyridone derivatives and use thereof
EP1745027A4 (en) * 2004-05-14 2009-06-03 Irm Llc COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS
RU2008135762A (ru) * 2006-02-16 2010-03-27 Де МакЛин Хоспитал Корпорейшн (US) Способы и композиции для лечения болезни паркинсона
AU2007275301A1 (en) 2006-07-20 2008-01-24 Amgen Inc. Substituted azole aromatic heterocycles as inhibitors of 11-beta-HSD-1
FR2906250B1 (fr) * 2006-09-22 2008-10-31 Sanofi Aventis Sa Derives de 2-aryl-6phenyl-imidazo(1,2-a) pyridines, leur preparation et leur application en therapeutique
FR2933609B1 (fr) * 2008-07-10 2010-08-27 Fournier Lab Sa Utilisation de derives d'indole comme activateurs de nurr-1, pour le traitement de la maladie de parkinson.
US8173670B2 (en) * 2009-01-13 2012-05-08 Van Andel Research Institute Methods of using substituted isoxazolo pyridinones as dissociated glucocorticoids
FR2950053B1 (fr) 2009-09-11 2014-08-01 Fournier Lab Sa Utilisation de derives d'indole benzoique comme activateurs de nurr-1, pour le traitement de la maladie de parkinson
FR2955110A1 (fr) 2010-01-08 2011-07-15 Fournier Lab Sa Nouveaux derives de type pyrrolopyridine benzoique
DE102011085038A1 (de) 2011-10-21 2013-04-25 Tesa Se Verfahren zur Kapselung einer elektronischen Anordnung
CN113845558A (zh) 2013-09-25 2021-12-28 范安德尔研究所 高效糖皮质激素
KR20170033630A (ko) 2015-09-17 2017-03-27 (주)다올 도로용 경계블럭
RU2019111101A (ru) 2016-10-14 2020-11-16 Ван Андель Рисерч Инститьют Структуры и механизм для дизайна высокоактивных глюкокортикоидов

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7602542L (sv) 1975-03-14 1976-09-15 Sandoz Ag 3-(alfa-iminobensyl)-4-hydroxi-2(lh)-pyridoner
US4064251A (en) * 1976-06-25 1977-12-20 Sandoz, Inc. Substituted hydroxy pyridones
US4049813A (en) * 1976-07-15 1977-09-20 Sandoz, Inc. Substituted isoxazolo pyridinones
US4238616A (en) * 1977-01-19 1980-12-09 Sandoz, Inc. 3-(Substituted)phenyl-5-(β-hydroxyphenethyl)-N-(alkyl)-isoxazole-4-carboxamides
DE2801190A1 (de) * 1977-01-19 1978-07-20 Sandoz Ag 3-(alpha-iminobenzyl)-4-hydroxy-2(1h)- pyridon-derivat
US4113727A (en) * 1977-04-26 1978-09-12 Sandoz, Inc. Process for the preparation of substituted isoxazolo[4,5-c]pyridin-4-(5H)-ones
CA2451057A1 (en) * 2001-06-14 2002-12-27 Banyu Pharmaceutical Co., Ltd. Novel isoxazolopyridone derivatives and use thereof

Also Published As

Publication number Publication date
DE60218484T2 (de) 2007-11-15
PT1418912E (pt) 2007-05-31
MXPA04001419A (es) 2004-05-27
PE20030356A1 (es) 2003-05-14
HUP0401325A2 (hu) 2004-10-28
EP1418912B1 (en) 2007-02-28
JP2005501847A (ja) 2005-01-20
NO20040659L (no) 2004-02-13
WO2003015780A8 (en) 2004-05-21
CA2454762A1 (en) 2003-02-27
RU2004107847A (ru) 2005-05-10
GB0119911D0 (en) 2001-10-10
KR20040029429A (ko) 2004-04-06
ZA200400525B (en) 2005-04-01
NO20040659D0 (no) 2004-02-13
CN100384418C (zh) 2008-04-30
CN1635889A (zh) 2005-07-06
ES2282467T3 (es) 2007-10-16
BR0211903A (pt) 2004-09-21
CO5560566A2 (es) 2005-09-30
US20040248893A1 (en) 2004-12-09
EP1418912A2 (en) 2004-05-19
WO2003015780A2 (en) 2003-02-27
PL366848A1 (en) 2005-02-07
DE60218484D1 (de) 2007-04-12
ECSP044971A (es) 2004-03-23
US7087756B2 (en) 2006-08-08
ATE355059T1 (de) 2006-03-15
AR036351A1 (es) 2004-09-01
HUP0401325A3 (en) 2005-09-28
WO2003015780A3 (en) 2003-11-13

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