IL153922A0 - Heparin-derived polysaccharide mixtures, preparation method and pharmaceutical compositions containing same - Google Patents

Heparin-derived polysaccharide mixtures, preparation method and pharmaceutical compositions containing same

Info

Publication number: IL153922A0
Authority: IL; Israel
Prior art keywords: heparin; preparation; pharmaceutical compositions; compositions containing; containing same
Prior art date: 2000-07-21

Application number

IL15392201A

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-07-21

Filing date

2001-07-18

Publication date

2003-07-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8852768&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL153922(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-07-18 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2003-07-31 Publication of IL153922A0 publication Critical patent/IL153922A0/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
- C08B37/0078—Degradation products
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Polymers & Plastics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Materials Engineering (AREA)
Biochemistry (AREA)
Hematology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)

IL15392201A 2000-07-21 2001-07-18 Heparin-derived polysaccharide mixtures, preparation method and pharmaceutical compositions containing same IL153922A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0009572A FR2811992B1 (en)	2000-07-21	2000-07-21	MIXTURES OF HEPARIN-DERIVED POLYSACCHARIDES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
PCT/FR2001/002332 WO2002008295A1 (en)	2000-07-21	2001-07-18	Heparin-derived polysaccharide mixtures, preparation method and pharmaceutical compositions containing same

Publications (1)

Publication Number	Publication Date
IL153922A0 true IL153922A0 (en)	2003-07-31

Family

ID=8852768

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL15392201A IL153922A0 (en)	2000-07-21	2001-07-18	Heparin-derived polysaccharide mixtures, preparation method and pharmaceutical compositions containing same
IL153922A IL153922A (en)	2000-07-21	2003-01-13	Heparin-derived polysaccharide mixtures, preparation method and pharmaceutical compositions containing same

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL153922A IL153922A (en)	2000-07-21	2003-01-13	Heparin-derived polysaccharide mixtures, preparation method and pharmaceutical compositions containing same

Country Status (36)

Country	Link
EP (1)	EP1307491B2 (en)
JP (1)	JP5279160B2 (en)
KR (1)	KR100853585B1 (en)
CN (1)	CN1230449C (en)
AP (1)	AP1703A (en)
AR (1)	AR029865A1 (en)
AT (1)	ATE470679T1 (en)
AU (2)	AU2001277602B2 (en)
BR (1)	BR0112612B1 (en)
CA (1)	CA2416673C (en)
CL (1)	CL2004001154A1 (en)
CY (1)	CY1110774T1 (en)
DE (1)	DE60142340D1 (en)
DK (1)	DK1307491T3 (en)
DZ (1)	DZ3411A1 (en)
EA (1)	EA005995B1 (en)
EC (1)	ECSP034442A (en)
ES (1)	ES2347134T5 (en)
FR (1)	FR2811992B1 (en)
HK (1)	HK1059273A1 (en)
HR (1)	HRP20030019A2 (en)
HU (1)	HUP0300755A3 (en)
IL (2)	IL153922A0 (en)
MA (1)	MA26928A1 (en)
MX (1)	MXPA03000579A (en)
NO (1)	NO20030296L (en)
NZ (1)	NZ524028A (en)
OA (1)	OA12340A (en)
PL (1)	PL202471B1 (en)
PT (1)	PT1307491E (en)
SI (1)	SI1307491T1 (en)
TW (1)	TWI307278B (en)
UA (1)	UA74836C2 (en)
WO (1)	WO2002008295A1 (en)
YU (1)	YU2903A (en)
ZA (1)	ZA200300898B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6969705B2 (en)	2000-07-21	2005-11-29	Aventis Pharma S.A.	Compositions of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
ATE356150T1 (en) *	2002-06-20	2007-03-15	Chemi Spa	METHOD FOR PRODUCING HEPARINE ESTERS
US20040171819A1 (en)	2002-10-10	2004-09-02	Aventis Pharma S.A.	Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
AR041555A1 (en)	2002-10-10	2005-05-18	Aventis Pharma Sa	MIXTURES OF POLYACARIDS DERIVED FROM HEPARINE, ITS PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2845686B1 (en) *	2002-10-10	2013-08-30	Aventis Pharma Sa	MIXTURES OF HEPARIN-DERIVED POLYSACCHARIDES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US7956046B2 (en) *	2003-07-24	2011-06-07	Aventis Pharma S.A.	Oligosaccharide mixtures derived from heparin, preparation thereof and pharmaceutical compositions containing them
FR2857971B1 (en) *	2003-07-24	2005-08-26	Aventis Pharma Sa	MIXTURES OF HEPARIN DERIVED OLIGOSACCHARIDES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
DE102004059134B4 (en)	2004-12-08	2011-12-15	Siemens Ag	Expansion device for an X-ray machine and X-ray source
CA2652205A1 (en) *	2006-05-25	2007-12-06	Mallik Sundaram	Low molecular weight heparin composition and uses thereof
CN101824099B (en) *	2010-02-12	2011-11-30	淮安麦德森化学有限公司	Method for purifying crude product heparin sodium
CN101824446B (en) *	2010-02-24	2012-12-12	淮安麦德森化学有限公司	Method for producing chondroitin sulfate by reverse precipitation
EP2399590A1 (en)	2010-06-25	2011-12-28	Aventis Pharma S.A.	Semuloparin for the prevention of a mortality and/or morbidity event in a patient undergoing major orthopaedic surgery
EP2399592A1 (en)	2010-06-25	2011-12-28	Aventis Pharma S.A.	Semuloparin for use as an antithrombotic treatment in hip replacement surgery with improved safety in terms of clinically relevant bleedings and major bleedings
EP2399591A1 (en)	2010-06-25	2011-12-28	Aventis Pharma S.A.	Semuloparin for the extended prevention of a mortality and/or morbidity event in a patient having undergone hip fracture surgery
EP2399593A1 (en)	2010-06-28	2011-12-28	Aventis Pharma S.A.	Semuloparin for use as an antithrombotic treatment in orthopaedic surgery with improved benefit-risk profile
CN102399379B (en) *	2010-09-09	2016-08-31	上海喜恩医药科技发展有限公司	Polysaccharide mixture of a kind of heparin derivative and preparation method thereof and pharmaceutical composition
DK3144325T3 (en) *	2010-09-14	2021-01-25	Univ Miyazaki	HIGH PURITY HEPARIN AND ITS MANUFACTURING PROCEDURE
WO2012055843A1 (en)	2010-10-28	2012-05-03	Aventis Pharma S.A.	Semuloparin for the prevention of major venous thromboembolism in a patient undergoing major abdominal surgery
EP2446891A1 (en)	2010-10-28	2012-05-02	Aventis Pharma S.A.	Semuloparin for use as an antithrombotic treatment in major abdominal surgery with improved safety in terms of clinically relevant bleedings and major bleedings
EP2548561A1 (en)	2011-07-22	2013-01-23	Aventis Pharma S.A.	Semuloparin for improving the survival of patients with locally advanced cancer
ES2445494B1 (en) *	2012-08-02	2015-03-06	Rovi Lab Farmaceut Sa	Procedure for obtaining low and very low molecular weight heparins
CN103175925B (en) *	2013-03-20	2014-12-03	山东辰中生物制药有限公司	Method for detecting esterification rate of heparin benzyl ester in production process of enoxaparin sodium
FR3016632A1 (en) *	2014-01-21	2015-07-24	IFP Energies Nouvelles	PROCESS FOR TRANSFORMING POLYSACCHARIDES TO OXYGENIC MOLECULES IN THE PRESENCE OF NEUTRAL ORGANIC SUPERBASES
CZ306662B6 (en) *	2015-06-26	2017-04-26	Contipro A.S.	Sulphated polysaccharides derivatives, the method of their preparation, the method of their modification and the use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2478646A2 (en) *	1980-03-20	1981-09-25	Choay Sa	MUCOPOLYSACCHARIDIC COMPOSITION HAVING A COAGULATION REGULATING ACTIVITY, MEDICAMENT CONTAINING THE SAME, AND METHOD FOR OBTAINING THE SAME
IL61201A (en) *	1979-10-05	1984-09-30	Choay Sa	Oligosaccharides having no more than 8 saccharide moieties,their obtention from heparin and pharmaceutical compositions containing them
FR2482611B1 (en) *	1980-05-14	1986-03-07	Pharmindustrie	NOVEL SULFATED POLYSACCHARIDES, METHODS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
US4916219A (en) *	1985-03-28	1990-04-10	University Of Iowa Research Foundation	Oligosaccharide heparin fragments as inhibitors of complement cascade
EP0337327A1 (en) *	1988-04-09	1989-10-18	Bioiberica, S.A.	Process for the preparation of new oligosaccharide fractions by controlled chemical depolimerization of heparin
ES2077533B1 (en) *	1994-02-28	1996-07-01	Bioiberica	PROCEDURE FOR OBTAINING OLIGOSACCHARIDE FRACTIONS BY CHEMICAL DEPOLYMERIZATION OF HEPARIN.
JP4897991B2 (en) *	1999-07-23	2012-03-14	ラボラトリオスファルマセウティコスロビソシエダッドアノニマ	Ultra low molecular weight heparin composition
ES2161615B1 (en) *	1999-07-23	2003-03-16	Rovi Lab Farmaceut Sa	COMPOSITIONS OF HEPARINS OF VERY LOW MOLECULAR WEIGHT.

2000
- 2000-07-21 FR FR0009572A patent/FR2811992B1/en not_active Expired - Fee Related
2001
- 2001-07-18 DK DK01955436.9T patent/DK1307491T3/en active
- 2001-07-18 EP EP01955436.9A patent/EP1307491B2/en not_active Expired - Lifetime
- 2001-07-18 HU HU0300755A patent/HUP0300755A3/en unknown
- 2001-07-18 SI SI200130977T patent/SI1307491T1/en unknown
- 2001-07-18 DZ DZ013411A patent/DZ3411A1/en active
- 2001-07-18 AU AU2001277602A patent/AU2001277602B2/en not_active Ceased
- 2001-07-18 IL IL15392201A patent/IL153922A0/en unknown
- 2001-07-18 AP APAP/P/2003/002744A patent/AP1703A/en active
- 2001-07-18 CA CA2416673A patent/CA2416673C/en not_active Expired - Fee Related
- 2001-07-18 AU AU7760201A patent/AU7760201A/en active Pending
- 2001-07-18 DE DE60142340T patent/DE60142340D1/en not_active Expired - Lifetime
- 2001-07-18 EA EA200300178A patent/EA005995B1/en not_active IP Right Cessation
- 2001-07-18 BR BRPI0112612-1A patent/BR0112612B1/en not_active IP Right Cessation
- 2001-07-18 NZ NZ52402801A patent/NZ524028A/en not_active IP Right Cessation
- 2001-07-18 PT PT01955436T patent/PT1307491E/en unknown
- 2001-07-18 KR KR1020037000689A patent/KR100853585B1/en not_active IP Right Cessation
- 2001-07-18 AT AT01955436T patent/ATE470679T1/en active
- 2001-07-18 JP JP2002514199A patent/JP5279160B2/en not_active Expired - Fee Related
- 2001-07-18 YU YU2903A patent/YU2903A/en unknown
- 2001-07-18 ES ES01955436.9T patent/ES2347134T5/en not_active Expired - Lifetime
- 2001-07-18 WO PCT/FR2001/002332 patent/WO2002008295A1/en active IP Right Grant
- 2001-07-18 OA OA1200300012A patent/OA12340A/en unknown
- 2001-07-18 PL PL365561A patent/PL202471B1/en not_active IP Right Cessation
- 2001-07-18 UA UA2003010495A patent/UA74836C2/en unknown
- 2001-07-18 MX MXPA03000579A patent/MXPA03000579A/en active IP Right Grant
- 2001-07-18 CN CNB018141870A patent/CN1230449C/en not_active Expired - Fee Related
- 2001-07-19 TW TW090117709A patent/TWI307278B/en not_active IP Right Cessation
- 2001-07-20 AR ARP010103476A patent/AR029865A1/en active IP Right Grant
2003
- 2003-01-10 MA MA26996A patent/MA26928A1/en unknown
- 2003-01-13 IL IL153922A patent/IL153922A/en not_active IP Right Cessation
- 2003-01-14 HR HR20030019A patent/HRP20030019A2/en not_active Application Discontinuation
- 2003-01-20 NO NO20030296A patent/NO20030296L/en not_active Application Discontinuation
- 2003-01-20 EC EC2003004442A patent/ECSP034442A/en unknown
- 2003-01-31 ZA ZA200300898A patent/ZA200300898B/en unknown
2004
- 2004-03-24 HK HK04102179A patent/HK1059273A1/en not_active IP Right Cessation
- 2004-05-19 CL CL200401154A patent/CL2004001154A1/en unknown
2010
- 2010-09-09 CY CY20101100819T patent/CY1110774T1/en unknown

Also Published As

Publication number	Publication date
AP2003002744A0 (en)	2003-03-31
AU7760201A (en)	2002-02-05
CY1110774T1 (en)	2015-06-10
EP1307491B1 (en)	2010-06-09
DE60142340D1 (en)	2010-07-22
ATE470679T1 (en)	2010-06-15
BR0112612B1 (en)	2011-07-12
KR20030040364A (en)	2003-05-22
CA2416673A1 (en)	2002-01-31
PT1307491E (en)	2010-09-10
TWI307278B (en)	2009-03-11
WO2002008295A1 (en)	2002-01-31
FR2811992A1 (en)	2002-01-25
EA200300178A1 (en)	2003-06-26
BR0112612A (en)	2003-07-29
CL2004001154A1 (en)	2005-05-27
EP1307491A1 (en)	2003-05-07
FR2811992B1 (en)	2003-07-04
AU2001277602B2 (en)	2007-07-19
ES2347134T5 (en)	2014-06-24
PL202471B1 (en)	2009-06-30
HRP20030019A2 (en)	2005-10-31
CN1447820A (en)	2003-10-08
UA74836C2 (en)	2006-02-15
HUP0300755A3 (en)	2004-03-01
CN1230449C (en)	2005-12-07
EP1307491B2 (en)	2014-05-07
SI1307491T1 (en)	2010-10-29
MXPA03000579A (en)	2003-06-06
NO20030296D0 (en)	2003-01-20
ZA200300898B (en)	2004-04-30
MA26928A1 (en)	2004-12-20
YU2903A (en)	2006-03-03
AR029865A1 (en)	2003-07-16
HK1059273A1 (en)	2004-06-25
JP5279160B2 (en)	2013-09-04
ES2347134T3 (en)	2010-10-26
HUP0300755A2 (en)	2003-12-29
NO20030296L (en)	2003-01-20
NZ524028A (en)	2004-12-24
PL365561A1 (en)	2005-01-10
DZ3411A1 (en)	2002-01-31
CA2416673C (en)	2011-06-14
DK1307491T3 (en)	2010-10-11
JP2004504451A (en)	2004-02-12
IL153922A (en)	2010-05-17
AP1703A (en)	2007-02-26
OA12340A (en)	2006-05-15
KR100853585B1 (en)	2008-08-21
EA005995B1 (en)	2005-08-25
ECSP034442A (en)	2003-03-10

Publication	Publication Date	Title
HK1059273A1 (en)	2004-06-25	Heparin-derived polysaccharide mixtures, preparation method and pharmaceutical compositions containing same
AU2001277602A1 (en)	2002-05-02	Heparin-derived polysaccharide mixtures, preparation method and pharmaceutical compositions containing same
DZ3313A1 (en)	2001-09-07	Azetidine derivatives, preparation thereof and pharmaceutical compositions containing same
IL138280A0 (en)	2001-10-31	20-KETO-11β-ARYLSTERIODS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR THE PREPARATION THEREOF
PL349448A1 (en)	2002-07-29	Benzopyrans and benzoxepines, pharmaceutical compositions comprising them and preparation process
HUP0203821A3 (en)	2003-10-28	Novel oligosaccharides, preparation method and pharmaceutical compositions containing same
ZA200109602B (en)	2003-01-29	Purine derivatives, preparation method and pharmaceutical compositions containing same.
PL356911A1 (en)	2004-07-12	Novel heterocyclic derivatives, preparation method and pharmaceutical compositions containing same
IL154240A0 (en)	2003-07-31	4-pyrimidinamine derivatives, pharmaceutical compositions and related methods
HUP0302515A3 (en)	2005-06-28	Sulfanidothienopyrimidines, process for their preparation and pharmaceutical compositions containing them
HUP0303195A3 (en)	2007-03-28	O-substituted 6-methyl-tramadol derivatives, process for their preparation and pharmaceutical compositions containing them
AU3560601A (en)	2001-08-07	Novel isoquinoline derivatives, preparation method and pharmaceutical compositions containing them
HUP0300330A3 (en)	2003-09-29	Oligosaccharides, pharmaceutical compositions containing them and preparation thereof
HUP0302905A3 (en)	2006-05-29	Triazolo-epothilone-analogs, process for their preparation and pharmaceutical compositions containing them
AU2207902A (en)	2002-06-11	Cyclohexyl(alkyl)-propanolamines, preparation method and pharmaceutical compositions containing same
HUP0303688A3 (en)	2005-06-28	Propanolaminotetralines, preparation thereof and pharmaceutical compositions containing same
IL135707A0 (en)	2001-05-20	19-norbufalin derivatives, their preparation and pharmaceutical compositions containing them
HUP0101503A3 (en)	2003-02-28	Heterocycloalkyl- and heteroaryl-benzocyclobutane derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0101504A3 (en)	2002-11-28	New cyclobutaindolecarboxamide derivatives, process for their preparation and pharmaceutical compositions containing them
IL152327A0 (en)	2003-05-29	19-norbufalin derivatives, their preparation and pharmaceutical compositions containing them
SI1252150T1 (en)	2003-10-31	Heterocyclic derivatives, preparation method and pharmaceutical compositions containing same
SI1032374T1 (en)	2003-10-31	Spheroids, preparation method and pharmaceutical compositions