IL145958A0 - Polymorphic form of arginine salt of (2s)-3-[4-[2-phenoxazin-10-yl)ethoxy] phenyl]2-ethoxypropanoic acid, processes for the preparation thereof and pharmaceutical compositions containing the same - Google Patents
Polymorphic form of arginine salt of (2s)-3-[4-[2-phenoxazin-10-yl)ethoxy] phenyl]2-ethoxypropanoic acid, processes for the preparation thereof and pharmaceutical compositions containing the sameInfo
- Publication number
- IL145958A0 IL145958A0 IL14595800A IL14595800A IL145958A0 IL 145958 A0 IL145958 A0 IL 145958A0 IL 14595800 A IL14595800 A IL 14595800A IL 14595800 A IL14595800 A IL 14595800A IL 145958 A0 IL145958 A0 IL 145958A0
- Authority
- IL
- Israel
- Prior art keywords
- phenoxazin
- ethoxy
- phenyl
- processes
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/38—[b, e]-condensed with two six-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IB1999/000681 WO2000063191A1 (en) | 1999-04-16 | 1999-04-16 | Novel polymorphic forms of an antidiabetic agent: process for their preparation and a pharmaceutical composition containing them |
IN436MA1999 | 1999-04-19 | ||
PCT/IB2000/000470 WO2000063192A1 (en) | 1999-04-16 | 2000-04-17 | Novel polymorphic forms of an antidiabetic agent: process for their preparation and pharmaceutical compositions containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
IL145958A0 true IL145958A0 (en) | 2002-07-25 |
Family
ID=26318745
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14595800A IL145958A0 (en) | 1999-04-16 | 2000-04-17 | Polymorphic form of arginine salt of (2s)-3-[4-[2-phenoxazin-10-yl)ethoxy] phenyl]2-ethoxypropanoic acid, processes for the preparation thereof and pharmaceutical compositions containing the same |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP1171430A1 (en) |
CN (1) | CN1351597A (en) |
AU (1) | AU3831300A (en) |
BG (1) | BG106022A (en) |
BR (1) | BR0010683A (en) |
CA (1) | CA2370401A1 (en) |
CZ (1) | CZ20013711A3 (en) |
EE (1) | EE200100529A (en) |
HR (1) | HRP20010748A2 (en) |
HU (1) | HUP0200758A3 (en) |
IL (1) | IL145958A0 (en) |
MX (1) | MXPA01010472A (en) |
NO (1) | NO20015016L (en) |
PL (1) | PL351492A1 (en) |
RU (1) | RU2001130883A (en) |
TR (1) | TR200103851T2 (en) |
WO (1) | WO2000063192A1 (en) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE309818T1 (en) | 2000-03-08 | 2005-12-15 | Novo Nordisk As | LOWERING SERUM CHOLESTEROL |
US6897199B2 (en) * | 2001-02-05 | 2005-05-24 | Dr. Reddy's Laboratories Ltd. | Pharmaceutically acceptable salts of phenoxazine and phenothiazine compounds |
WO2003031432A1 (en) | 2001-10-12 | 2003-04-17 | Novo Nordisk A/S | Substituted piperidines and their use for the treatment of diseases related to the histamine h3 receptor |
US20030171411A1 (en) | 2001-12-21 | 2003-09-11 | Kodra Janos Tibor | Amide derivatives as therapeutic agents |
JP5142448B2 (en) * | 2002-04-19 | 2013-02-13 | ファエス・ファルマ・ソシエダッド・アノニマ | 4- [2- [1- (2-Ethoxyethyl) -1H-benzimidazol-2-yl] -1-piperidinyl] ethyl] -α, α-dimethylbenzenoacetic acid polymorph |
KR101116627B1 (en) | 2002-06-27 | 2012-10-09 | 노보 노르디스크 에이/에스 | Aryl carbonyl derivatives as therapeutic agents |
WO2004101505A1 (en) | 2003-05-14 | 2004-11-25 | Novo Nordisk A/S | Novel compounds for treatment of obesity |
WO2005030797A2 (en) | 2003-09-30 | 2005-04-07 | Novo Nordisk A/S | Melanocortin receptor agonists |
JP4865565B2 (en) | 2003-12-09 | 2012-02-01 | ノヴォ ノルディスク アー/エス | Controlling food selection using GLP-1 agonists |
SI1723128T1 (en) | 2004-01-06 | 2013-04-30 | Transtech Pharma, Inc. | Heteroaryl-ureas and their use as glucokinase activators |
WO2005105785A2 (en) | 2004-05-04 | 2005-11-10 | Novo Nordisk A/S | Indole derivatives for treatment of obesity |
EP2316446A1 (en) | 2004-06-11 | 2011-05-04 | Novo Nordisk A/S | Counteracting drug-induced obesity using GLP-1 agonists |
CN101060856B (en) | 2004-11-22 | 2011-01-19 | 诺和诺德公司 | Soluble, stable insulin-containing formulations with a protamine salt |
CA2590720A1 (en) | 2004-12-03 | 2006-06-08 | Lone Jeppesen | Heteroaromatic glucokinase activators |
JP5121707B2 (en) | 2005-07-04 | 2013-01-16 | ハイ ポイント ファーマシューティカルズ,エルエルシー | New medicine |
ES2422383T3 (en) | 2005-07-14 | 2013-09-11 | Novo Nordisk As | Urea glucokinase activators |
US8106090B2 (en) | 2005-07-20 | 2012-01-31 | Eli Lilly And Company | 1-amino linked compounds |
WO2007123581A1 (en) | 2005-11-17 | 2007-11-01 | Eli Lilly And Company | Glucagon receptor antagonists, preparation and therapeutic uses |
AU2007229492B2 (en) | 2006-03-28 | 2011-11-03 | High Point Pharmaceuticals, Llc | Benzothiazoles having histamine H3 receptor activity |
SG163547A1 (en) | 2006-05-29 | 2010-08-30 | High Point Pharmaceuticals Llc | 3- (1, 3-benz0di0x0l-5-yl) -6- (4-cyclopropylpiperazin-1-yl) -pyridazine, its salts and solvates and its use as histamine h3 receptor antagonist |
CA2669874A1 (en) | 2006-11-15 | 2008-05-22 | High Point Pharmaceuticals, Llc | Novel 2-(2-hydroxyphenyl) benzothiadiazines useful for treating obesity and diabetes |
ATE523497T1 (en) | 2006-11-15 | 2011-09-15 | High Point Pharmaceuticals Llc | NEW 2-(2-HYDROXYPHENYL)BENZIMIDAZOLES SUITABLE FOR THE TREATMENT OF OBESITAS AND DIABETES |
AU2008204530B2 (en) | 2007-01-11 | 2013-08-01 | Vtv Therapeutics Llc | Urea glucokinase activators |
JP2010013472A (en) * | 2009-09-09 | 2010-01-21 | Faes Farma Sa | POLYMORPH OF 4-[2-[1-(2-ETHOXYETHYL)-1H-BENZIMIDAZOL-2-YL]-1-PIPERIDINYL] ETHYL-alpha,alpha-DIMETHYL BENZENOACETIC ACID |
BR112012021231A2 (en) | 2010-02-26 | 2015-09-08 | Basf Plant Science Co Gmbh | method for enhancing plant yield, plant, construct, use of a construct, method for producing a transgenic plant, collectable parts of a plant, products derived from a plant, use of a nucleic acid and method for producing a product |
WO2011104378A1 (en) | 2010-02-26 | 2011-09-01 | Novo Nordisk A/S | Peptides for treatment of obesity |
BR112012024379A2 (en) | 2010-03-26 | 2017-01-10 | Novo Nordisk As | "glucagon peptides, their use as well as pharmaceutical composition" |
EP2670368A4 (en) | 2011-02-03 | 2015-04-15 | Pharmedica Ltd | New oral dissolving films for insulin administration, for treating diabetes |
AU2012234276A1 (en) | 2011-03-28 | 2013-08-29 | Novo Nordisk A/S | Novel glucagon analogues |
MX354705B (en) | 2011-09-23 | 2018-03-16 | Novo Nordisk As | Novel glucagon analogues. |
US20150004144A1 (en) | 2011-12-02 | 2015-01-01 | The General Hospital Corporation | Differentiation into brown adipocytes |
MY174727A (en) | 2013-04-18 | 2020-05-11 | Novo Nordisk As | Stable, protracted glp-1/glucagon receptor co-agonists for medical use |
US10570184B2 (en) | 2014-06-04 | 2020-02-25 | Novo Nordisk A/S | GLP-1/glucagon receptor co-agonists for medical use |
JP2020514365A (en) | 2017-03-15 | 2020-05-21 | ノヴォ ノルディスク アー/エス | Bicyclic compound capable of binding to melanocortin 4 receptor |
WO2019219714A1 (en) | 2018-05-15 | 2019-11-21 | Novo Nordisk A/S | Compounds capable of binding to melanocortin 4 receptor |
WO2020053414A1 (en) | 2018-09-14 | 2020-03-19 | Novo Nordisk A/S | Bicyclic compounds capable of acting as melanocortin 4 receptor agonists |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5089514A (en) * | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
US5248699A (en) * | 1992-08-13 | 1993-09-28 | Pfizer Inc. | Sertraline polymorph |
IN182496B (en) * | 1996-02-20 | 1999-04-17 | Reddy Research Foundation | |
GB9604242D0 (en) * | 1996-02-28 | 1996-05-01 | Glaxo Wellcome Inc | Chemical compounds |
FR2746099B1 (en) * | 1996-03-13 | 1998-04-30 | IMPROVED PROCESS FOR THE PREPARATION OF 3- (10-PHENOTHIAZYL) -PROPANOIC OR 3- (10-PHENOXAZYL) -PROPANOIC ACID DERIVATIVES | |
EP0844997A1 (en) * | 1996-06-19 | 1998-06-03 | Dr. Reddy's Research Foundation | Novel polymorphic forms of troglitazone having enhanced anti-diabetic activity and a process for their preparation |
WO1999019313A1 (en) * | 1997-10-27 | 1999-04-22 | Dr. Reddy's Research Foundation | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them |
JP2002501909A (en) * | 1998-01-29 | 2002-01-22 | ドクター・レディーズ・リサーチ・ファウンデーション | Novel alkanoic acid and its use in medicine, its production process and pharmaceutical composition containing it |
PL341795A1 (en) * | 1998-05-27 | 2001-05-07 | Reddy Research Foundation | Bicycle compounds, process for obtaining them and pharmacological compositions containing such compounds |
-
2000
- 2000-04-17 MX MXPA01010472A patent/MXPA01010472A/en unknown
- 2000-04-17 EE EEP200100529A patent/EE200100529A/en unknown
- 2000-04-17 EP EP00917222A patent/EP1171430A1/en not_active Withdrawn
- 2000-04-17 BR BR0010683-6A patent/BR0010683A/en not_active IP Right Cessation
- 2000-04-17 RU RU2001130883/04A patent/RU2001130883A/en unknown
- 2000-04-17 CN CN00807705A patent/CN1351597A/en active Pending
- 2000-04-17 WO PCT/IB2000/000470 patent/WO2000063192A1/en active Search and Examination
- 2000-04-17 PL PL00351492A patent/PL351492A1/en not_active Application Discontinuation
- 2000-04-17 CZ CZ20013711A patent/CZ20013711A3/en unknown
- 2000-04-17 CA CA002370401A patent/CA2370401A1/en not_active Abandoned
- 2000-04-17 TR TR2001/03851T patent/TR200103851T2/en unknown
- 2000-04-17 IL IL14595800A patent/IL145958A0/en unknown
- 2000-04-17 HU HU0200758A patent/HUP0200758A3/en unknown
- 2000-04-17 AU AU38313/00A patent/AU3831300A/en not_active Abandoned
-
2001
- 2001-10-15 HR HR20010748A patent/HRP20010748A2/en not_active Application Discontinuation
- 2001-10-15 NO NO20015016A patent/NO20015016L/en not_active Application Discontinuation
- 2001-10-16 BG BG106022A patent/BG106022A/en unknown
Also Published As
Publication number | Publication date |
---|---|
BR0010683A (en) | 2003-07-01 |
TR200103851T2 (en) | 2002-04-22 |
EE200100529A (en) | 2002-12-16 |
WO2000063192A1 (en) | 2000-10-26 |
CA2370401A1 (en) | 2000-10-26 |
MXPA01010472A (en) | 2002-05-06 |
NO20015016D0 (en) | 2001-10-15 |
RU2001130883A (en) | 2004-03-20 |
HUP0200758A2 (en) | 2002-07-29 |
EP1171430A1 (en) | 2002-01-16 |
CN1351597A (en) | 2002-05-29 |
PL351492A1 (en) | 2003-04-22 |
BG106022A (en) | 2002-04-30 |
HUP0200758A3 (en) | 2003-07-28 |
AU3831300A (en) | 2000-11-02 |
CZ20013711A3 (en) | 2002-07-17 |
NO20015016L (en) | 2001-12-11 |
HRP20010748A2 (en) | 2003-02-28 |
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