IL132524A - Crystalline state of napazodone hydrochloride dehydrate and process for its production - Google Patents

Crystalline state of napazodone hydrochloride dehydrate and process for its production

Info

Publication number
IL132524A
IL132524A IL13252499A IL13252499A IL132524A IL 132524 A IL132524 A IL 132524A IL 13252499 A IL13252499 A IL 13252499A IL 13252499 A IL13252499 A IL 13252499A IL 132524 A IL132524 A IL 132524A
Authority
IL
Israel
Prior art keywords
nefazodone
purification
crystalline
hydrochloride dihydrate
organic solvent
Prior art date
Application number
IL13252499A
Other languages
English (en)
Hebrew (he)
Other versions
IL132524A0 (en
Original Assignee
Finaf 92 Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Finaf 92 Sa filed Critical Finaf 92 Sa
Publication of IL132524A0 publication Critical patent/IL132524A0/xx
Publication of IL132524A publication Critical patent/IL132524A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL13252499A 1998-10-23 1999-10-21 Crystalline state of napazodone hydrochloride dehydrate and process for its production IL132524A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES009802223A ES2152860B1 (es) 1998-10-23 1998-10-23 Forma cristalina de la nefazodona y procedimiento para su preparacion.

Publications (2)

Publication Number Publication Date
IL132524A0 IL132524A0 (en) 2001-03-19
IL132524A true IL132524A (en) 2001-11-25

Family

ID=8305559

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13252499A IL132524A (en) 1998-10-23 1999-10-21 Crystalline state of napazodone hydrochloride dehydrate and process for its production

Country Status (5)

Country Link
US (1) US6448404B1 (es)
EP (1) EP1000944A1 (es)
CA (1) CA2287105A1 (es)
ES (1) ES2152860B1 (es)
IL (1) IL132524A (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2356450C (en) 2001-09-10 2003-11-25 Brantford Chemicals Inc. An improved process for the preparation of nefazodone hydrochloride
DE102004021494B4 (de) * 2004-04-30 2006-04-06 Man Roland Druckmaschinen Ag Vorrichtung zum Auf- und Abziehen einer Hülse
WO2012072665A1 (en) 2010-11-30 2012-06-07 Pharmaneuroboost N.V. Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1052119B (it) * 1972-10-16 1981-06-20 Sigma Tau Ind Farmaceuti Derivati del triazolinone e procedimento per la loro preparazione
US4338317A (en) * 1981-03-16 1982-07-06 Mead Johnson & Company Phenoxyethyl-1,2,4,-triazol-3-one antidepressants
US4487773A (en) * 1981-03-16 1984-12-11 Mead Johnson & Company 1,2,4-Triazol-3-one antidepressants
US5256664A (en) * 1992-04-28 1993-10-26 Bristol-Myers Squibb Company Antidepressant 3-halophenylpiperazinylpropyl derivatives of substituted triazolones and triazoldiones
IT1256387B (it) * 1992-11-13 1995-12-04 Acraf Procedimento per preparare triazoloni
CA2160423A1 (en) * 1994-11-02 1996-05-03 Hemant N. Joshi Salts of nefazodone having improved dissolution rates
BR9708347A (pt) * 1996-03-25 1999-08-03 Lilly Co Eli Compostos de tetrahidorbeta-carbonila

Also Published As

Publication number Publication date
US6448404B1 (en) 2002-09-10
IL132524A0 (en) 2001-03-19
CA2287105A1 (en) 2000-04-23
ES2152860B1 (es) 2001-08-16
ES2152860A1 (es) 2001-02-01
EP1000944A1 (en) 2000-05-17

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Legal Events

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KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees