IL116101A - 4-amino-5-chloro-2,3-dihydro-n-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzo-furancarboxamide its preparation and pharmaceutical compositions containing it - Google Patents

4-amino-5-chloro-2,3-dihydro-n-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzo-furancarboxamide its preparation and pharmaceutical compositions containing it

Info

Publication number: IL116101A
Authority: IL; Israel
Prior art keywords: furancarboxamide; methoxypropyl; piperidinyl; benzo; dihydro
Prior art date: 1994-11-24

Application number

IL11610195A

Other languages

English (en)

Other versions

IL116101A0 (en

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-11-24

Filing date

1995-11-23

Publication date

1999-08-17

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8217407&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL116101(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-11-23 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1996-01-31 Publication of IL116101A0 publication Critical patent/IL116101A0/xx

1999-08-17 Publication of IL116101A publication Critical patent/IL116101A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

IL11610195A 1994-11-24 1995-11-23 4-amino-5-chloro-2,3-dihydro-n-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzo-furancarboxamide its preparation and pharmaceutical compositions containing it IL116101A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP94203421		1994-11-24

Publications (2)

Publication Number	Publication Date
IL116101A0 IL116101A0 (en)	1996-01-31
IL116101A true IL116101A (en)	1999-08-17

Family

ID=8217407

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL11610195A IL116101A (en)	1994-11-24	1995-11-23	4-amino-5-chloro-2,3-dihydro-n-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzo-furancarboxamide its preparation and pharmaceutical compositions containing it

Country Status (40)

Country	Link
US (3)	US5854260A (xx)
EP (1)	EP0807110B1 (xx)
JP (1)	JP3046076B2 (xx)
KR (1)	KR100233489B1 (xx)
CN (1)	CN1071332C (xx)
AP (1)	AP777A (xx)
AR (1)	AR001769A1 (xx)
AT (1)	ATE217306T1 (xx)
AU (1)	AU704043B2 (xx)
BG (1)	BG63710B1 (xx)
BR (1)	BRPI9509819B8 (xx)
CA (1)	CA2205573C (xx)
CY (2)	CY2296B1 (xx)
CZ (1)	CZ292847B6 (xx)
DE (2)	DE69526679T2 (xx)
DK (1)	DK0807110T3 (xx)
EE (1)	EE03313B1 (xx)
ES (1)	ES2177671T3 (xx)
FI (1)	FI120147B (xx)
FR (1)	FR10C0001I2 (xx)
HR (1)	HRP950571B1 (xx)
HU (1)	HU226560B1 (xx)
IL (1)	IL116101A (xx)
LU (1)	LU91644I2 (xx)
MY (1)	MY112944A (xx)
NL (1)	NL300435I1 (xx)
NO (3)	NO312726B1 (xx)
NZ (1)	NZ297753A (xx)
OA (1)	OA10422A (xx)
PL (1)	PL183713B1 (xx)
PT (1)	PT807110E (xx)
RO (1)	RO116279B1 (xx)
RU (1)	RU2154643C2 (xx)
SI (1)	SI0807110T1 (xx)
SK (1)	SK283499B6 (xx)
TR (1)	TR199501483A2 (xx)
TW (1)	TW490465B (xx)
UA (1)	UA59334C2 (xx)
WO (1)	WO1996016060A1 (xx)
ZA (1)	ZA959996B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW490465B (en) *	1994-11-24	2002-06-11	Janssen Pharmaceutica Nv	Enterokinetic benzamide, the preparation process and the pharmaceutical compositions thereof
TW402591B (en) *	1997-07-11	2000-08-21	Janssen Pharmaceutica Nv	Monocyclic benzamides of 3- or 4-substituted 4-(aminomethyl)-piperidine derivatives
CA2332275A1 (en) *	1998-05-14	1999-11-18	Zoltan Tamas Nagy	Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
CA2352278A1 (en) *	1998-11-23	2000-06-02	Janssen Pharmaceutica, N.V.	Use of prucalopride for the manufacture of a medicament for the treatment of dyspepsia
TW592709B (en) *	1999-04-29	2004-06-21	Janssen Pharmaceutica Nv	Prucalopride oral solution
CN1288730A (zh) *	1999-09-07	2001-03-28	麦克内尔-Ppc股份有限公司	轻泻组合物
AU2003206722B2 (en) *	2002-01-16	2008-01-24	Mercury Pharma Group Limited	Prucalopride-N-oxide
TW201118084A (en) *	2009-09-18	2011-06-01	Adolor Corp	The use of an opioid receptor antagonist for the treatment or prevention of gastrointestinal tract disorders
GB201103397D0 (xx)	2011-02-28	2011-04-13	Shire Movetis N V
CN102295594B (zh) *	2011-07-12	2016-01-20	上海医药工业研究院	4-n-取代-1-(3-甲氧基丙基)-4-哌啶胺类化合物及制备和应用
WO2013024164A1 (en)	2011-08-18	2013-02-21	Shire Ag	Combinations of a 5-ht4 receptor agonist and a pde4 inhibitor for use in therapy
EP3413891B1 (en)	2016-02-11	2024-01-03	Symed Labs Limited	Processes for the preparation of highly pure prucalopride succinate
CN108727351B (zh) *	2017-04-19	2021-08-31	鲁南制药集团股份有限公司	一种普芦卡必利的精制方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5374637A (en) *	1989-03-22	1994-12-20	Janssen Pharmaceutica N.V.	N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives
GB9005014D0 (en) *	1990-03-06	1990-05-02	Janssen Pharmaceutica Nv	N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives
TW490465B (en) *	1994-11-24	2002-06-11	Janssen Pharmaceutica Nv	Enterokinetic benzamide, the preparation process and the pharmaceutical compositions thereof

1995
- 1995-11-08 TW TW084111813A patent/TW490465B/zh not_active IP Right Cessation
- 1995-11-16 ES ES95941613T patent/ES2177671T3/es not_active Expired - Lifetime
- 1995-11-16 UA UA97052121A patent/UA59334C2/uk unknown
- 1995-11-16 PL PL95320297A patent/PL183713B1/pl unknown
- 1995-11-16 CN CN95196347A patent/CN1071332C/zh not_active Expired - Lifetime
- 1995-11-16 HU HU9702127A patent/HU226560B1/hu active Protection Beyond IP Right Term
- 1995-11-16 EE EE9700116A patent/EE03313B1/xx not_active IP Right Cessation
- 1995-11-16 NZ NZ297753A patent/NZ297753A/en not_active IP Right Cessation
- 1995-11-16 AP APAP/P/1997/000992A patent/AP777A/en active
- 1995-11-16 AU AU42992/96A patent/AU704043B2/en not_active Expired
- 1995-11-16 DE DE69526679T patent/DE69526679T2/de not_active Expired - Lifetime
- 1995-11-16 BR BRPI9509819A patent/BRPI9509819B8/pt not_active IP Right Cessation
- 1995-11-16 EP EP95941613A patent/EP0807110B1/en not_active Expired - Lifetime
- 1995-11-16 DE DE201012000002 patent/DE122010000002I1/de active Pending
- 1995-11-16 JP JP8516549A patent/JP3046076B2/ja not_active Expired - Lifetime
- 1995-11-16 WO PCT/EP1995/004519 patent/WO1996016060A1/en active IP Right Grant
- 1995-11-16 US US08/836,276 patent/US5854260A/en not_active Expired - Lifetime
- 1995-11-16 RO RO97-00942A patent/RO116279B1/ro unknown
- 1995-11-16 SK SK652-97A patent/SK283499B6/sk not_active IP Right Cessation
- 1995-11-16 CZ CZ19971555A patent/CZ292847B6/cs not_active IP Right Cessation
- 1995-11-16 DK DK95941613T patent/DK0807110T3/da active
- 1995-11-16 RU RU97110232/04A patent/RU2154643C2/ru active
- 1995-11-16 AT AT95941613T patent/ATE217306T1/de active
- 1995-11-16 PT PT95941613T patent/PT807110E/pt unknown
- 1995-11-16 KR KR1019970703419A patent/KR100233489B1/ko not_active IP Right Cessation
- 1995-11-16 SI SI9530593T patent/SI0807110T1/xx unknown
- 1995-11-16 CA CA002205573A patent/CA2205573C/en not_active Expired - Lifetime
- 1995-11-23 ZA ZA959996A patent/ZA959996B/xx unknown
- 1995-11-23 IL IL11610195A patent/IL116101A/xx not_active IP Right Cessation
- 1995-11-23 HR HR950571A patent/HRP950571B1/xx not_active IP Right Cessation
- 1995-11-23 AR AR33436095A patent/AR001769A1/es unknown
- 1995-11-24 MY MYPI95003617A patent/MY112944A/en unknown
- 1995-11-24 TR TR95/01483A patent/TR199501483A2/xx unknown
1997
- 1997-05-09 NO NO19972143A patent/NO312726B1/no not_active IP Right Cessation
- 1997-05-23 FI FI972203A patent/FI120147B/fi active Protection Beyond IP Right Term
- 1997-05-23 OA OA70012A patent/OA10422A/en unknown
- 1997-06-11 BG BG101605A patent/BG63710B1/bg unknown
1998
- 1998-09-24 US US09/159,993 patent/US5948794A/en not_active Expired - Lifetime
1999
- 1999-06-04 US US09/325,865 patent/US6310077B1/en not_active Expired - Lifetime
2002
- 2002-09-20 CY CY0200055A patent/CY2296B1/xx unknown
2010
- 2010-01-06 FR FR10C0001C patent/FR10C0001I2/fr active Active
- 2010-01-15 CY CY2010001C patent/CY2010001I1/el unknown
- 2010-01-27 LU LU91644C patent/LU91644I2/en unknown
- 2010-02-09 NL NL300435C patent/NL300435I1/nl unknown
- 2010-03-05 NO NO2010003C patent/NO2010003I2/no unknown
2019
- 2019-12-11 NO NO2019044C patent/NO2019044I1/no unknown

Also Published As

Publication number	Publication date
SK283499B6 (sk)	2003-08-05
TW490465B (en)	2002-06-11
NO2010003I1 (no)	2010-03-05
PL183713B1 (pl)	2002-07-31
BRPI9509819B8 (pt)	2021-07-06
AU704043B2 (en)	1999-04-15
CA2205573A1 (en)	1996-05-30
NO312726B1 (no)	2002-06-24
BG63710B1 (bg)	2002-10-31
ZA959996B (en)	1997-05-23
JPH09512832A (ja)	1997-12-22
LU91644I2 (en)	2010-03-29
CA2205573C (en)	2006-05-09
PT807110E (pt)	2002-10-31
DK0807110T3 (da)	2002-09-02
CZ292847B6 (cs)	2003-12-17
AP777A (en)	1999-10-28
PL320297A1 (en)	1997-09-15
CN1164233A (zh)	1997-11-05
US5854260A (en)	1998-12-29
EE03313B1 (et)	2000-12-15
BRPI9509819B1 (pt)	2018-05-15
MX9703869A (es)	1997-09-30
OA10422A (en)	2002-03-19
KR100233489B1 (ko)	1999-12-01
DE69526679T2 (de)	2002-12-05
IL116101A0 (en)	1996-01-31
RU2154643C2 (ru)	2000-08-20
FR10C0001I1 (xx)	2010-02-12
BR9509819A (pt)	1997-09-30
HU226560B1 (en)	2009-04-28
CY2010001I2 (el)	2010-07-28
WO1996016060A1 (en)	1996-05-30
AU4299296A (en)	1996-06-17
BG101605A (en)	1998-02-27
FI120147B (fi)	2009-07-15
SI0807110T1 (en)	2002-08-31
RO116279B1 (ro)	2000-12-29
JP3046076B2 (ja)	2000-05-29
HRP950571A2 (en)	1997-08-31
CN1071332C (zh)	2001-09-19
FI972203A (fi)	1997-05-23
DE122010000002I1 (de)	2011-12-01
AR001769A1 (es)	1997-12-10
NO972143L (no)	1997-05-09
US5948794A (en)	1999-09-07
ATE217306T1 (de)	2002-05-15
EP0807110B1 (en)	2002-05-08
NZ297753A (en)	1998-05-27
NO2010003I2 (no)	2012-08-27
CZ155597A3 (en)	1997-09-17
US6310077B1 (en)	2001-10-30
NL300435I1 (nl)	2010-04-01
DE69526679D1 (de)	2002-06-13
EP0807110A1 (en)	1997-11-19
FR10C0001I2 (fr)	2011-04-01
FI972203A0 (fi)	1997-05-23
ES2177671T3 (es)	2002-12-16
NO972143D0 (no)	1997-05-09
SK65297A3 (en)	1997-10-08
CY2296B1 (en)	2003-07-04
AP9700992A0 (en)	1997-07-31
HUT77375A (hu)	1998-04-28
UA59334C2 (uk)	2003-09-15
CY2010001I1 (el)	2010-07-28
TR199501483A2 (tr)	1996-07-21
NO2019044I1 (no)	2019-12-11
MY112944A (en)	2001-10-31
HRP950571B1 (en)	2001-12-31

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Legal Events

Date	Code	Title
1999-12-22	FF	Patent granted
2000-08-13	KB	Patent renewed
2002-02-10	KB	Patent renewed
2010-05-17	KB	Patent renewed
2013-10-31	KB	Patent renewed
2016-06-30	EXP	Patent expired