IL112288A - Use of riluzole in the manufacture of a medicament for the treatment of mitochondrial diseases - Google Patents
Use of riluzole in the manufacture of a medicament for the treatment of mitochondrial diseasesInfo
- Publication number
- IL112288A IL112288A IL11228895A IL11228895A IL112288A IL 112288 A IL112288 A IL 112288A IL 11228895 A IL11228895 A IL 11228895A IL 11228895 A IL11228895 A IL 11228895A IL 112288 A IL112288 A IL 112288A
- Authority
- IL
- Israel
- Prior art keywords
- treatment
- pct
- riluzole
- mitochondrial diseases
- medicament
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Nutrition Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9400249A FR2714828B1 (fr) | 1994-01-12 | 1994-01-12 | Application du riluzole dans le traitement des maladies mitochondriales. |
Publications (2)
Publication Number | Publication Date |
---|---|
IL112288A0 IL112288A0 (en) | 1995-03-30 |
IL112288A true IL112288A (en) | 1999-04-11 |
Family
ID=9458947
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL11228895A IL112288A (en) | 1994-01-12 | 1995-01-09 | Use of riluzole in the manufacture of a medicament for the treatment of mitochondrial diseases |
Country Status (14)
Country | Link |
---|---|
US (1) | US5686475A (xx) |
EP (1) | EP0738147B1 (xx) |
JP (1) | JP3585045B2 (xx) |
AT (1) | ATE191342T1 (xx) |
AU (1) | AU1458495A (xx) |
DE (1) | DE69516110T2 (xx) |
DK (1) | DK0738147T3 (xx) |
ES (1) | ES2145902T3 (xx) |
FR (1) | FR2714828B1 (xx) |
GR (1) | GR3033005T3 (xx) |
IL (1) | IL112288A (xx) |
PT (1) | PT738147E (xx) |
WO (1) | WO1995019170A1 (xx) |
ZA (1) | ZA95150B (xx) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20000048847A (ko) | 1996-10-01 | 2000-07-25 | 스즈키 다다시 | 미토콘드리아 막 안정화제 |
US5922746A (en) * | 1997-03-27 | 1999-07-13 | Allergan | Inhibition of noninactivating Na channels of mammalian optic nerve as a means of preventing optic nerve degeneration associated with glaucoma |
FR2774592B1 (fr) * | 1998-02-06 | 2000-03-17 | Rhone Poulenc Rorer Sa | Application du 2-amino-6-trifluoromethoxybenzothiazole pour la prevention ou le traitement des dysfonctionnements du cervelet |
FR2774908B1 (fr) * | 1998-02-17 | 2000-06-23 | Centre Nat Rech Scient | Utilisation d'inhibiteur de la liberation du glutamate dans le traitement de l'ischemie retinienne |
FR2787028B1 (fr) * | 1998-12-15 | 2002-10-18 | Aventis Pharma Sa | Utilisation du riluzole dans le traitement des traumatismes acoustiques |
US6239156B1 (en) * | 1999-04-29 | 2001-05-29 | Centre National De La Recherche Scientifique Cnrs | Method for the prevention of ischemic spinal cord injury caused by aortic crossclamping |
CA2429567A1 (en) | 2000-11-22 | 2002-05-30 | Allergan, Inc. | A high-throughput screen for identifying channel blockers that selectively distinguish transient from persistent sodium channels |
US6479458B1 (en) | 2001-11-08 | 2002-11-12 | Allergan, Inc. | Targeting the reverse mode of the Na+/Ca2+ exchanger for the treatment of optic neuropathy associated with glaucoma and ischemic optic neuropathy |
US7361478B2 (en) | 2001-11-20 | 2008-04-22 | Allergan, Inc. | High-throughput screen for identifying selective persistent sodium channels channel blockers |
JP2004182705A (ja) * | 2002-10-11 | 2004-07-02 | Yasutoshi Koga | ミトコンドリア機能異常に起因する疾患における臨床症状発現の予防・治療用組成物 |
CA2661448A1 (en) | 2005-08-25 | 2007-03-01 | Steven Michael Weiss | Reducing myocardial damage and the incidence of arrhythmia arising from loss, reduction or interruption in coronary blood flow |
EP2243476A1 (en) * | 2009-04-17 | 2010-10-27 | Centre National de la Recherche Scientifique | Compounds for the treatment of mitochondrial diseases |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4826860A (en) * | 1987-03-16 | 1989-05-02 | Warner-Lambert Company | Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents |
US5236940A (en) * | 1988-12-15 | 1993-08-17 | Rhone-Poulenc Sante | Pharmaceutical compositions, 2-benzothiazolamine derivatives, and their preparation |
ES2043070T3 (es) * | 1988-12-15 | 1993-12-16 | Rhone Poulenc Sante | Procedimiento para la preparacion de derivados de la benzotiazolamina-2. |
US5334618A (en) * | 1991-04-04 | 1994-08-02 | The Children's Medical Center Corporation | Method of preventing NMDA receptor-mediated neuronal damage |
US5455279A (en) * | 1991-04-19 | 1995-10-03 | The Children's Medical Center Corporation | Regimen method of mediating neuronal damage using nitroglycerine |
FR2688138B1 (fr) * | 1992-03-06 | 1995-05-05 | Rhone Poulenc Rorer Sa | Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la sclerose laterale amyotrophique. |
-
1994
- 1994-01-12 FR FR9400249A patent/FR2714828B1/fr not_active Expired - Fee Related
-
1995
- 1995-01-09 EP EP95906378A patent/EP0738147B1/fr not_active Expired - Lifetime
- 1995-01-09 AU AU14584/95A patent/AU1458495A/en not_active Abandoned
- 1995-01-09 IL IL11228895A patent/IL112288A/xx not_active IP Right Cessation
- 1995-01-09 PT PT95906378T patent/PT738147E/pt unknown
- 1995-01-09 DK DK95906378T patent/DK0738147T3/da active
- 1995-01-09 ES ES95906378T patent/ES2145902T3/es not_active Expired - Lifetime
- 1995-01-09 JP JP51887095A patent/JP3585045B2/ja not_active Expired - Fee Related
- 1995-01-09 DE DE69516110T patent/DE69516110T2/de not_active Expired - Lifetime
- 1995-01-09 US US08/669,530 patent/US5686475A/en not_active Expired - Lifetime
- 1995-01-09 WO PCT/FR1995/000023 patent/WO1995019170A1/fr active IP Right Grant
- 1995-01-09 AT AT95906378T patent/ATE191342T1/de active
- 1995-01-10 ZA ZA95150A patent/ZA95150B/xx unknown
-
2000
- 2000-04-06 GR GR990403136T patent/GR3033005T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ATE191342T1 (de) | 2000-04-15 |
DE69516110T2 (de) | 2000-09-28 |
DK0738147T3 (da) | 2000-07-10 |
IL112288A0 (en) | 1995-03-30 |
ES2145902T3 (es) | 2000-07-16 |
JP3585045B2 (ja) | 2004-11-04 |
ZA95150B (en) | 1995-09-07 |
EP0738147B1 (fr) | 2000-04-05 |
PT738147E (pt) | 2000-08-31 |
WO1995019170A1 (fr) | 1995-07-20 |
AU1458495A (en) | 1995-08-01 |
US5686475A (en) | 1997-11-11 |
FR2714828B1 (fr) | 1996-02-02 |
FR2714828A1 (fr) | 1995-07-13 |
EP0738147A1 (fr) | 1996-10-23 |
JPH09507498A (ja) | 1997-07-29 |
DE69516110D1 (de) | 2000-05-11 |
GR3033005T3 (en) | 2000-07-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
EXP | Patent expired |