IL110040A - Pyridazinone derivatives their preparation and pharmaceutical compositions comprising them - Google Patents

Pyridazinone derivatives their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL110040A
IL110040A IL11004094A IL11004094A IL110040A IL 110040 A IL110040 A IL 110040A IL 11004094 A IL11004094 A IL 11004094A IL 11004094 A IL11004094 A IL 11004094A IL 110040 A IL110040 A IL 110040A
Authority
IL
Israel
Prior art keywords
group
atom
alkyl group
pct
hydrogen atom
Prior art date
Application number
IL11004094A
Other languages
English (en)
Other versions
IL110040A0 (en
Original Assignee
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd
Publication of IL110040A0 publication Critical patent/IL110040A0/xx
Publication of IL110040A publication Critical patent/IL110040A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/22—Nitrogen and oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL11004094A 1993-06-29 1994-06-17 Pyridazinone derivatives their preparation and pharmaceutical compositions comprising them IL110040A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP15919493 1993-06-29
JP11272194 1994-05-26

Publications (2)

Publication Number Publication Date
IL110040A0 IL110040A0 (en) 1994-10-07
IL110040A true IL110040A (en) 2000-07-16

Family

ID=26451823

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11004094A IL110040A (en) 1993-06-29 1994-06-17 Pyridazinone derivatives their preparation and pharmaceutical compositions comprising them

Country Status (22)

Country Link
US (2) US5728702A (fr)
EP (1) EP0706517B1 (fr)
KR (1) KR100255416B1 (fr)
CN (1) CN1044906C (fr)
AT (1) ATE172454T1 (fr)
AU (1) AU676341B2 (fr)
CA (1) CA2166326C (fr)
CZ (1) CZ289231B6 (fr)
DE (1) DE69414112T2 (fr)
DK (1) DK0706517T3 (fr)
ES (1) ES2124413T3 (fr)
FI (1) FI113963B (fr)
HU (1) HU221009B1 (fr)
IL (1) IL110040A (fr)
NO (1) NO306675B1 (fr)
NZ (1) NZ267510A (fr)
RO (1) RO114791B1 (fr)
RU (1) RU2138486C1 (fr)
SK (1) SK280786B6 (fr)
TW (1) TW408114B (fr)
UA (1) UA34481C2 (fr)
WO (1) WO1995001343A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE192741T1 (de) * 1994-01-25 2000-05-15 Nissan Chemical Ind Ltd Pyridazinon-derivate
DE4430755A1 (de) * 1994-08-30 1996-03-07 Boehringer Mannheim Gmbh Neue Phosphanoxide, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
US6207665B1 (en) 1997-06-12 2001-03-27 Schering Aktiengesellschaft Piperazine derivatives and their use as anti-inflammatory agents
CA2326506A1 (fr) * 1998-03-31 1999-10-07 Nissan Chemical Industries, Ltd. Compose d'hydrochlorure de pyridazinone et procede de production
CN1166653C (zh) * 1999-11-11 2004-09-15 日产化学工业株式会社 苄胺化合物的制造方法
WO2003035627A1 (fr) 2001-10-22 2003-05-01 Pfizer Products Inc. Derives de piperazine a activite antagoniste du recepteur ccr1
US20060080140A1 (en) * 2004-02-09 2006-04-13 Epic Systems Corporation System and method for providing a clinical summary of patient information in various health care settings
WO2010099388A1 (fr) * 2009-02-27 2010-09-02 Indigo Pharmaceuticals Utilisation combinée d'un inhibiteur de la pde3 et d'autres agents
CN116768868B (zh) * 2023-08-15 2023-12-08 云南省药物研究所 一种哒嗪酮硫代衍生物及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0186817B1 (fr) * 1984-12-10 1989-08-02 Nissan Chemical Industries Ltd. (2H)-Pyridazinone-3, procédé pour sa préparation et agent antiallergique la contenant
JPH0641454B2 (ja) * 1985-02-27 1994-06-01 日産化学工業株式会社 ピリダジノン誘導体
US4892947A (en) * 1985-04-27 1990-01-09 Nissan Chemical Industries Ltd. 3(2H)Pyridazinone, process for its preparation and anti-allergic agent containing it
US4978665A (en) * 1987-01-20 1990-12-18 Nissan Chemical Industries Ltd. 3(2H)pyridazinone, and antagonistic agent against SRS-A containing it
JPH02256668A (ja) * 1988-12-20 1990-10-17 Nissan Chem Ind Ltd ピリダジノン誘導体
UA27031A1 (uk) * 1990-04-25 2000-02-28 Ніссан Кемікал Індастріз Лтд Похідhі 3(2h)піридазиhоhу або їх фармацевтичhо прийhятhі солі, що мають протитромботичhу, позитивhу іhотропhу, судиhорозширювальhу дію й аhтиалергічhу активhість та фармацевтичhа композиція hа їх осhові
ATE192741T1 (de) * 1994-01-25 2000-05-15 Nissan Chemical Ind Ltd Pyridazinon-derivate

Also Published As

Publication number Publication date
NO306675B1 (no) 1999-12-06
RU2138486C1 (ru) 1999-09-27
CZ329995A3 (en) 1996-04-17
US5728702A (en) 1998-03-17
FI113963B (fi) 2004-07-15
ATE172454T1 (de) 1998-11-15
KR960703401A (ko) 1996-08-17
DE69414112D1 (de) 1998-11-26
UA34481C2 (uk) 2001-03-15
NO955328L (no) 1996-02-28
DK0706517T3 (da) 1999-06-28
DE69414112T2 (de) 1999-03-11
CA2166326C (fr) 2005-02-01
ES2124413T3 (es) 1999-02-01
IL110040A0 (en) 1994-10-07
CA2166326A1 (fr) 1995-01-12
KR100255416B1 (ko) 2000-05-01
FI956300A (fi) 1995-12-28
CN1126470A (zh) 1996-07-10
HU9503807D0 (en) 1996-02-28
WO1995001343A1 (fr) 1995-01-12
US5929074A (en) 1999-07-27
HU221009B1 (hu) 2002-07-29
NZ267510A (en) 1996-10-28
EP0706517A1 (fr) 1996-04-17
EP0706517B1 (fr) 1998-10-21
SK162495A3 (en) 1996-11-06
NO955328D0 (no) 1995-12-28
CZ289231B6 (cs) 2001-12-12
AU6983394A (en) 1995-01-24
SK280786B6 (sk) 2000-07-11
RO114791B1 (ro) 1999-07-30
HUT73483A (en) 1996-08-28
TW408114B (en) 2000-10-11
FI956300A0 (fi) 1995-12-28
CN1044906C (zh) 1999-09-01
AU676341B2 (en) 1997-03-06

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees