IL102261A - תולדות של חומצות 7-איזואינדוליניל-קווינולן-ו- נפתירידונקרבוקסיליות, הכנתן ותכשירירוקחות המכילים אותן - Google Patents

תולדות של חומצות 7-איזואינדוליניל-קווינולן-ו- נפתירידונקרבוקסיליות, הכנתן ותכשירירוקחות המכילים אותן

Info

Publication number
IL102261A
IL102261A IL10226192A IL10226192A IL102261A IL 102261 A IL102261 A IL 102261A IL 10226192 A IL10226192 A IL 10226192A IL 10226192 A IL10226192 A IL 10226192A IL 102261 A IL102261 A IL 102261A
Authority
IL
Israel
Prior art keywords
methyl
oxo
dihydro
acid
cyclopropyl
Prior art date
Application number
IL10226192A
Other languages
English (en)
Other versions
IL102261A0 (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Priority to IL11665692A priority Critical patent/IL116656A/en
Publication of IL102261A0 publication Critical patent/IL102261A0/xx
Publication of IL102261A publication Critical patent/IL102261A/he

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL10226192A 1991-06-22 1992-06-19 תולדות של חומצות 7-איזואינדוליניל-קווינולן-ו- נפתירידונקרבוקסיליות, הכנתן ותכשירירוקחות המכילים אותן IL102261A (he)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL11665692A IL116656A (en) 1991-06-22 1992-06-19 4-Amino-1, 3, 3a, 4, 7, 7a- hexahydroisoindole compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4120646A DE4120646A1 (de) 1991-06-22 1991-06-22 7-isoindolinyl-chinolon- und naphthyridoncarbonsaeure-derivate

Publications (2)

Publication Number Publication Date
IL102261A0 IL102261A0 (en) 1993-01-14
IL102261A true IL102261A (he) 1996-10-16

Family

ID=6434522

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10226192A IL102261A (he) 1991-06-22 1992-06-19 תולדות של חומצות 7-איזואינדוליניל-קווינולן-ו- נפתירידונקרבוקסיליות, הכנתן ותכשירירוקחות המכילים אותן

Country Status (20)

Country Link
US (1) US5464796A (he)
EP (1) EP0520240A1 (he)
JP (1) JPH05239051A (he)
KR (1) KR930000503A (he)
CN (1) CN1068115A (he)
AU (1) AU648669B2 (he)
CA (1) CA2071677A1 (he)
CZ (1) CZ190192A3 (he)
DE (1) DE4120646A1 (he)
FI (1) FI922873A (he)
HU (1) HUT62288A (he)
IE (1) IE922003A1 (he)
IL (1) IL102261A (he)
MX (1) MX9202982A (he)
NO (1) NO922226L (he)
NZ (1) NZ243214A (he)
PH (1) PH30227A (he)
RU (1) RU2056411C1 (he)
SK (1) SK190192A3 (he)
TW (1) TW202442B (he)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4230804A1 (de) * 1992-09-15 1994-03-17 Bayer Ag 7-Isoindolinyl-chinolon- und -naphthyridon-Derivate
US5527910A (en) * 1992-12-30 1996-06-18 Cheil Foods & Chemicals, Inc. Pyridone carboxylic acid compounds and their uses for treating infectious diseases caused by bacteria
DE4301246A1 (de) * 1993-01-19 1994-07-21 Bayer Ag Chinolon- und Naphthyridoncarbonsäurederivate
US5532239A (en) * 1993-08-02 1996-07-02 Assistance Publique - Hopitaux De Paris Therapeutic application of fluoroquinolone derivatives
DE4329600A1 (de) * 1993-09-02 1995-03-09 Bayer Ag Pyrido [1,2,3-d,e] [1,3,4] benzoxadiazinderivate
DE4418510A1 (de) * 1994-05-27 1995-11-30 Bayer Ag 1,9-überbrückte Thiazolol[3,4-a]chinolinderivate
DE4427530A1 (de) * 1994-08-04 1996-02-08 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate
DE4435479A1 (de) * 1994-10-04 1996-04-11 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate
DE19500792A1 (de) * 1995-01-13 1996-07-18 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate
JPH08213881A (ja) * 1995-02-02 1996-08-20 Fujitsu Ltd 周波数制御回路
DE19506535A1 (de) * 1995-02-09 1996-08-14 Bayer Ag 1,6-Naphthyridoncarbonsäurederivate
DE19512484A1 (de) 1995-04-04 1996-10-17 Bayer Ag Kohlenhydratmodifizierte Cytostatika
WO1999014214A1 (en) * 1997-09-15 1999-03-25 The Procter & Gamble Company Antimicrobial quinolones, their compositions and uses
PA8466701A1 (es) 1998-01-21 2000-09-29 Pfizer Prod Inc Comprimido de mesilato de trovafloxacino
US7220824B1 (en) 2000-08-28 2007-05-22 Bayer Aktiengesellschaft Integrin-mediated drug targeting
EP1219634A1 (en) * 2000-12-27 2002-07-03 Bayer Aktiengesellschaft Cytostatic-glycoconjugates having specifically cleavable peptidic linking units
EP1238678A1 (en) * 2001-03-08 2002-09-11 Bayer Aktiengesellschaft Enzyme-activated cytostatic conjugates with integrin ligands
US7973022B2 (en) 2006-02-17 2011-07-05 Idexx Laboratories, Inc. Fluoroquinolone carboxylic acid salt compositions
US20070197548A1 (en) * 2006-02-17 2007-08-23 Murthy Yerramilli V S Fluoroquinolone compositions
US20070196398A1 (en) * 2006-02-17 2007-08-23 Murthy Yerramilli V S Fluoroquinolone fatty acid salt compositions
MX2008012488A (es) * 2006-03-28 2008-10-10 Procter & Gamble Un proceso de acoplamiento para preparar intermedios de quinolona.
SMP200800058B (it) * 2006-03-28 2009-09-07 Procter & Gamble Sali e polimorfi malati di un acido (3s, 5s) -7- [3-ammino-5-metilpiperidinil]-1-ciclopropil-1,4-diidro-8-metossi-4-osso-3-chinolincarbossilico
KR100690084B1 (ko) * 2006-11-01 2007-03-09 주식회사 세홍이엔씨 출입문과 연동하는 주택 내 배전반
WO2013111158A2 (en) * 2012-01-03 2013-08-01 Msn Laboratories Limited Process for the preparation of dpp-iv inhibitor

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5746986A (en) * 1980-09-02 1982-03-17 Dai Ichi Seiyaku Co Ltd Pyrido(1,2,3-de)(1,4)benzoxazine derivative
NZ208470A (en) * 1983-07-18 1988-06-30 Abbott Lab 6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives and antibacterial compositions containing such
NZ210847A (en) * 1984-01-26 1988-02-29 Abbott Lab Naphthyridine and pyridopyrimidine derivatives and pharmaceutical compositions
DE3577089D1 (de) * 1984-01-26 1990-05-17 Abbott Lab Antibakterielle chinolinderivate.
DE3420743A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-dihalogen-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
GB8612137D0 (en) * 1986-05-19 1986-06-25 Fujisawa Pharmaceutical Co Quinolone compounds
JPH0262875A (ja) * 1988-05-23 1990-03-02 Wakunaga Pharmaceut Co Ltd 新規イソインドリン誘導体
JP2844079B2 (ja) * 1988-05-23 1999-01-06 塩野義製薬株式会社 ピリドンカルボン酸系抗菌剤
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
JPH04504852A (ja) * 1989-04-26 1992-08-27 ジ・アップジョン・カンパニー 抗菌性ピリド(1,2,3―デ)―1,4―ベンゾオキサジノン剤
CA2030217A1 (en) * 1989-11-21 1991-05-22 Jun Imose Pyridone-carboxylic acid derivatives useful as veterinary medicines

Also Published As

Publication number Publication date
EP0520240A1 (de) 1992-12-30
FI922873A (fi) 1992-12-23
NZ243214A (en) 1995-07-26
RU2056411C1 (ru) 1996-03-20
SK190192A3 (en) 1995-08-09
FI922873A0 (fi) 1992-06-18
CZ190192A3 (en) 1993-01-13
NO922226D0 (no) 1992-06-05
CN1068115A (zh) 1993-01-20
AU1739192A (en) 1992-12-24
AU648669B2 (en) 1994-04-28
TW202442B (he) 1993-03-21
US5464796A (en) 1995-11-07
MX9202982A (es) 1992-12-01
PH30227A (en) 1997-02-05
HU9202085D0 (en) 1992-09-28
IE922003A1 (en) 1992-12-30
CA2071677A1 (en) 1992-12-23
HUT62288A (en) 1993-04-28
IL102261A0 (en) 1993-01-14
KR930000503A (ko) 1993-01-15
DE4120646A1 (de) 1992-12-24
NO922226L (no) 1992-12-23
JPH05239051A (ja) 1993-09-17

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