IL100946A0 - Structural gene of pneumococcal protein - Google Patents

Structural gene of pneumococcal protein

Info

Publication number
IL100946A0
IL100946A0 IL100946A IL10094692A IL100946A0 IL 100946 A0 IL100946 A0 IL 100946A0 IL 100946 A IL100946 A IL 100946A IL 10094692 A IL10094692 A IL 10094692A IL 100946 A0 IL100946 A0 IL 100946A0
Authority
IL
Israel
Prior art keywords
structural gene
nucleic acid
pneumococcal protein
pspa
protein
Prior art date
Application number
IL100946A
Other languages
English (en)
Original Assignee
Uab Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uab Research Foundation filed Critical Uab Research Foundation
Publication of IL100946A0 publication Critical patent/IL100946A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/28—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL100946A 1991-02-15 1992-02-14 Structural gene of pneumococcal protein IL100946A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65677391A 1991-02-15 1991-02-15

Publications (1)

Publication Number Publication Date
IL100946A0 true IL100946A0 (en) 1992-11-15

Family

ID=24634503

Family Applications (1)

Application Number Title Priority Date Filing Date
IL100946A IL100946A0 (en) 1991-02-15 1992-02-14 Structural gene of pneumococcal protein

Country Status (16)

Country Link
US (1) US5728387A (no)
EP (2) EP0786521A1 (no)
JP (3) JP3215109B2 (no)
AT (1) ATE168132T1 (no)
AU (1) AU692678C (no)
CA (1) CA2104014C (no)
DE (1) DE69226167T2 (no)
DK (1) DK0571538T5 (no)
ES (1) ES2118812T3 (no)
FI (1) FI933580A (no)
HK (1) HK1013629A1 (no)
IE (2) IE20000062A1 (no)
IL (1) IL100946A0 (no)
NO (1) NO313999B1 (no)
WO (1) WO1992014488A1 (no)
ZA (1) ZA921025B (no)

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US5965141A (en) * 1991-02-15 1999-10-12 Uab Research Foundation Epitopic regions of pneumococcal surface protein a
US6027734A (en) * 1991-02-15 2000-02-22 Uab Research Foundation Mucosal administration of pneumococcal antigens
US6232116B1 (en) 1991-02-15 2001-05-15 University Of Alabama At Birmingham Research Foundation Oral administration of pneumococcal antigens
US6592876B1 (en) * 1993-04-20 2003-07-15 Uab Research Foundation Pneumococcal genes, portions thereof, expression products therefrom, and uses of such genes, portions and products
US5980909A (en) * 1991-02-15 1999-11-09 Uab Research Foundation Epitopic regions of pneumococcal surface protein A
US6231870B1 (en) * 1995-06-02 2001-05-15 Uab Research Foundation Oral administration of pneumoccal antigens
CA2116261A1 (en) * 1993-04-20 1994-10-21 David E. Briles Epitopic regions of pneumococcal surface protein a
US5928900A (en) * 1993-09-01 1999-07-27 The Rockefeller University Bacterial exported proteins and acellular vaccines based thereon
AU734488B2 (en) * 1994-05-20 2001-06-14 Uab Research Foundation Mucosal administration of pneumococcal antigens
US6001564A (en) * 1994-09-12 1999-12-14 Infectio Diagnostic, Inc. Species specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
US20020055101A1 (en) 1995-09-11 2002-05-09 Michel G. Bergeron Specific and universal probes and amplification primers to rapidly detect and identify common bacterial pathogens and antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
WO1996039113A2 (en) * 1995-06-02 1996-12-12 Uab Research Foundation Oral administration of pneumococcal antigens
US6004802A (en) * 1995-06-02 1999-12-21 University Of Alabama At Birmingham Oral administration of pneumococcal antigens
WO1996040718A1 (en) * 1995-06-07 1996-12-19 Connaught Laboratories, Inc. Expression of lipoproteins
ZA964896B (en) 1995-06-07 1997-01-08 Connaught Lab Expression of lipoproteins
HUP0600442A3 (en) * 1995-06-07 2007-03-28 Biochem Vaccines Inc Streptococcal heat shock proteins members of the hsp70 family
US6251405B1 (en) 1995-06-07 2001-06-26 Connaught Laboratories, Inc. Immunological combination compositions and methods
US5994066A (en) * 1995-09-11 1999-11-30 Infectio Diagnostic, Inc. Species-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
US7078042B2 (en) 1995-09-15 2006-07-18 Uab Research Foundation Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
US5949537A (en) 1996-04-18 1999-09-07 American Air Liquide Inc. In-line cell for absorption spectroscopy
US6165989A (en) * 1996-05-14 2000-12-26 Smithkline Beecham Corporation Era of Streptococcus pneumoniae
JP2002512501A (ja) 1996-07-03 2002-04-23 メリアル インコーポレイテッド 外来性ｄｎａを含む組換えイヌアデノウィルス（ｃａｖ）
US5882896A (en) * 1996-09-24 1999-03-16 Smithkline Beecham Corporation M protein
US5928895A (en) * 1996-09-24 1999-07-27 Smithkline Beecham Corporation IgA Fc binding protein
US20100267012A1 (en) 1997-11-04 2010-10-21 Bergeron Michel G Highly conserved genes and their use to generate probes and primers for detection of microorganisms
US20030049636A1 (en) 1999-05-03 2003-03-13 Bergeron Michel G. Species-specific, genus-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial and fungal pathogens and associated antibiotic resistance genes from clinical specimens for diagnosis in microbiology laboratories
AU5523798A (en) * 1996-12-04 1998-06-29 University Of Alabama At Birmingham Compositions and methods for administering pneumococcal DNA
KR19980067137A (ko) * 1997-01-31 1998-10-15 박원훈 알긴산염 초미세과립구를 이용한 폐렴구균 감연중에 대한 백신
CA2304128A1 (en) * 1997-09-18 1999-03-25 Robert Becker Improved method of production of pneumococcal surface proteins
US6224882B1 (en) 1997-11-07 2001-05-01 Protein Science Corp. Insect cells or fractions as adjuvant for antigens
US20010016200A1 (en) * 1998-04-23 2001-08-23 Briles David E. Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
EP1246935B1 (en) 1999-09-28 2013-08-14 Geneohm Sciences Canada Inc. Highly conserved genes and their use to generate probes and primers for detection of microorganisms
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
AT410412B (de) 2000-11-10 2003-04-25 Inteco Int Techn Beratung Verfahren zum elektroschlacke umschmelzen von metallen
EP2275121B1 (en) * 2002-04-02 2013-06-12 Ben Gurion University Of The Negev Research And Development Authority Protein-based streptococcus pneumoniae vaccines
US8691243B2 (en) 2002-04-02 2014-04-08 Ben-Gurion University Of The Negev Research And Development Authority Protein-based Streptococcus pneumoniae vaccine
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
AR058592A1 (es) 2005-12-22 2008-02-13 Glaxosmithkline Biolog Sa Vacuna
CA2636566C (en) 2006-01-17 2018-03-13 Arne Forsgren A novel surface exposed haemophilus influenzae protein (protein e; pe)
CN101883583B (zh) 2007-06-26 2017-05-17 葛兰素史密丝克莱恩生物有限公司 含有肺炎链球菌荚膜多糖缀合物的疫苗
EP2612680B1 (en) 2008-04-16 2018-05-23 GlaxoSmithKline Biologicals SA Vaccine
EP2711020B1 (en) 2008-05-02 2016-08-10 BliNK Therapeutics Limited Products and methods for stimulating an immune response
US20130011424A1 (en) 2010-03-09 2013-01-10 Timur ARTEMEV Polyepitope constructs and methods for their preparation and use
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
JP6227407B2 (ja) 2010-05-14 2017-11-08 バクスアルタ インコーポレイテッド Ｏｓｐａキメラおよびそのワクチンでの使用法
WO2012023033A2 (en) 2010-08-18 2012-02-23 Purdue Pharma L.P. Improved peptide immunogens
US20140072622A1 (en) 2011-05-17 2014-03-13 Glaxosmithkline Biologicals S.A. Vaccine against streptococcus pneumoniae
CA2879689A1 (en) 2012-07-27 2014-01-30 Baxter International Inc. Compositions comprising chimeric ospa molecules and methods of use thereof
JP5854537B2 (ja) 2012-09-19 2016-02-09 国立大学法人大阪大学 肺炎球菌表面タンパク質ａを含む肺炎球菌ワクチン
US9815886B2 (en) 2014-10-28 2017-11-14 Adma Biologics, Inc. Compositions and methods for the treatment of immunodeficiency
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KR102608642B1 (ko) 2016-12-03 2023-11-30 더 유에이비 리서치 파운데이션 폐렴구균 표면 단백질 a의 선택된 알파 나선 도메인 및 프롤린 풍부 도메인을 조합한 폐렴구균 백신
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection
CN110499375B (zh) * 2019-08-28 2023-03-28 首钢医院有限公司 结合多交叉置换扩增和金纳米检测肺炎链球菌的方法
WO2023240124A1 (en) 2022-06-07 2023-12-14 Regeneron Pharmaceuticals, Inc. Pseudotyped viral particles for targeting tcr-expressing cells
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US4496538A (en) * 1982-07-06 1985-01-29 Connaught Laboratories, Inc. Haemophilus influenzae b polysaccharide-diphtheria toxoid conjugate vaccine

Also Published As

Publication number Publication date
IE920479A1 (en) 1992-08-26
US5728387A (en) 1998-03-17
FI933580A (fi) 1993-10-13
DE69226167D1 (de) 1998-08-13
JPH09224680A (ja) 1997-09-02
HK1013629A1 (en) 1999-11-26
NO932890D0 (no) 1993-08-13
AU667668B2 (en) 1996-04-04
CA2104014C (en) 2000-05-02
EP0571538A1 (en) 1993-12-01
DK0571538T3 (da) 1999-04-19
JPH06504446A (ja) 1994-05-26
EP0571538B1 (en) 1998-07-08
ZA921025B (en) 1992-11-25
WO1992014488A1 (en) 1992-09-03
DE69226167T2 (de) 1998-11-12
IE20000062A1 (en) 2000-12-13
EP0571538A4 (en) 1994-08-24
DK0571538T5 (da) 2002-03-04
ATE168132T1 (de) 1998-07-15
CA2104014A1 (en) 1992-08-16
AU4798096A (en) 1996-06-27
ES2118812T3 (es) 1998-10-01
NO313999B1 (no) 2003-01-13
JP2001204482A (ja) 2001-07-31
FI933580A0 (fi) 1993-08-13
AU692678B2 (en) 1998-06-11
EP0786521A1 (en) 1997-07-30
NO932890L (no) 1993-10-14
JP3215109B2 (ja) 2001-10-02
AU1445392A (en) 1992-09-15
AU692678C (en) 2002-08-29

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