IL100418A0 - Analogs of acidic fibroblast growth factor having enhanced stability and biological activity - Google Patents

Analogs of acidic fibroblast growth factor having enhanced stability and biological activity

Info

Publication number
IL100418A0
IL100418A0 IL100418A IL10041891A IL100418A0 IL 100418 A0 IL100418 A0 IL 100418A0 IL 100418 A IL100418 A IL 100418A IL 10041891 A IL10041891 A IL 10041891A IL 100418 A0 IL100418 A0 IL 100418A0
Authority
IL
Israel
Prior art keywords
analogs
growth factor
biological activity
fibroblast growth
enhanced stability
Prior art date
Application number
IL100418A
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of IL100418A0 publication Critical patent/IL100418A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • C07K14/501—Fibroblast growth factor [FGF] acidic FGF [aFGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL100418A 1990-12-18 1991-12-18 Analogs of acidic fibroblast growth factor having enhanced stability and biological activity IL100418A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63245690A 1990-12-18 1990-12-18

Publications (1)

Publication Number Publication Date
IL100418A0 true IL100418A0 (en) 1992-09-06

Family

ID=24535601

Family Applications (1)

Application Number Title Priority Date Filing Date
IL100418A IL100418A0 (en) 1990-12-18 1991-12-18 Analogs of acidic fibroblast growth factor having enhanced stability and biological activity

Country Status (9)

Country Link
EP (1) EP0575339A4 (en)
JP (1) JPH06503962A (en)
KR (1) KR930703439A (en)
AU (1) AU663067B2 (en)
CA (1) CA2098484A1 (en)
IE (1) IE914393A1 (en)
IL (1) IL100418A0 (en)
NZ (1) NZ241021A (en)
WO (1) WO1992011360A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2717495B1 (en) * 1994-03-18 1996-04-12 Rhone Poulenc Rorer Sa Recombinant viruses, preparation and use in gene therapy.
AU3828195A (en) * 1994-10-13 1996-08-07 Amgen, Inc. Analogs of acidic fibroblast growth factor having enhanced stability and biological activity
DE122006000019I1 (en) * 1994-10-13 2006-06-29 Amgen Inc Method for purifying keratinocyte growth factors
JP2733207B2 (en) * 1995-05-18 1998-03-30 工業技術院長 Pharmaceutical composition containing fibroblast growth factor chimeric protein
US6743422B1 (en) 1996-10-15 2004-06-01 Amgen, Inc. Keratinocyte growth factor-2 products
US7125856B1 (en) 1999-04-15 2006-10-24 St. Elizabeth's Medical Center Of Boston, Inc. Angiogenic growth factors for treatment of peripheral neuropathy
CA2365434A1 (en) * 1999-04-15 2000-10-26 St. Elizabeth's Medical Center Of Boston Angiogenic growth factors for treatment of peripheral neuropathy
US20070134204A1 (en) * 2005-12-09 2007-06-14 Henrich Cheng Method for treating nerve injury and vector construct for the same
JP5004250B2 (en) * 2007-10-12 2012-08-22 独立行政法人産業技術総合研究所 Pharmaceutical composition containing highly functional chimeric protein

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989000198A1 (en) * 1987-07-07 1989-01-12 Biotechnology Research Associates, J.V. Recombinant fibroblast growth factors
EP0241136A3 (en) * 1986-03-07 1989-12-27 The President And Fellows Of Harvard College Human class 1 heparin-binding growth factor
NZ226543A (en) * 1987-10-22 1992-02-25 Merck & Co Inc Recombinant mutant acidic fibroblast growth factor
DE3909009A1 (en) * 1989-03-18 1990-09-20 Schloemann Siemag Ag CONTINUOUS CASTING SYSTEM FOR CASTING PROFILES

Also Published As

Publication number Publication date
EP0575339A1 (en) 1993-12-29
JPH06503962A (en) 1994-05-12
AU663067B2 (en) 1995-09-28
NZ241021A (en) 1993-12-23
KR930703439A (en) 1993-11-30
EP0575339A4 (en) 1995-04-05
WO1992011360A1 (en) 1992-07-09
CA2098484A1 (en) 1992-06-19
IE914393A1 (en) 1992-07-01
AU9152491A (en) 1992-07-22

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