IES20180088A2 - Drugs intermediates 2-ethylhexanoic acid synthesis method - Google Patents
Drugs intermediates 2-ethylhexanoic acid synthesis methodInfo
- Publication number
- IES20180088A2 IES20180088A2 IES20180088A IES20180088A IES20180088A2 IE S20180088 A2 IES20180088 A2 IE S20180088A2 IE S20180088 A IES20180088 A IE S20180088A IE S20180088 A IES20180088 A IE S20180088A IE S20180088 A2 IES20180088 A2 IE S20180088A2
- Authority
- IE
- Ireland
- Prior art keywords
- solution
- ethylhexanoic acid
- synthesis method
- acid synthesis
- extracted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Drugs intermediates 2-ethylhexanoic acid synthesis method, comprises the following steps: 3 mol 1-amino-2-bromo-3-ethylheptene, 4-5 mol dimethyl fumarate solution were added to the reaction vessel, controlled the stirring speed at 130-160 rpm, raised the temperature of the solution to 40-48°C, reacted for 2-3 h, washed with potassium nitrate solution for 4-6 times, adjusted the pH to 3-4 with potassium hydrogen sulfate solution, after the solution layered, extracted 5-7 times by 1,3-propanediamine solution, extracted 6-9 times by propylene glycol methyl ether solution, recrystallized from N-propylaniline solution, obtained 2-ethylhexanoic acid.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710215504.9A CN108238892A (en) | 2017-04-05 | 2017-04-05 | A kind of synthetic method of pharmaceutical intermediate 2 ethyl hexanoic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IES20180088A2 true IES20180088A2 (en) | 2019-04-03 |
| IES86993B2 IES86993B2 (en) | 2019-05-01 |
Family
ID=59220567
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IES20180088A IES86993B2 (en) | 2017-04-05 | 2018-04-03 | Drugs intermediates 2-ethylhexanoic acid synthesis method |
Country Status (4)
| Country | Link |
|---|---|
| CN (1) | CN108238892A (en) |
| AU (1) | AU2018100422A4 (en) |
| GB (1) | GB201708118D0 (en) |
| IE (1) | IES86993B2 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109134538B (en) * | 2018-09-25 | 2021-05-14 | 万华化学集团股份有限公司 | Iodophosphine oxide ligands, method for the production thereof, complexes, catalyst systems comprising the complexes and use thereof |
-
2017
- 2017-04-05 CN CN201710215504.9A patent/CN108238892A/en active Pending
- 2017-05-22 GB GBGB1708118.3A patent/GB201708118D0/en not_active Ceased
-
2018
- 2018-04-01 AU AU2018100422A patent/AU2018100422A4/en not_active Ceased
- 2018-04-03 IE IES20180088A patent/IES86993B2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018100422A4 (en) | 2018-05-17 |
| IES86993B2 (en) | 2019-05-01 |
| GB201708118D0 (en) | 2017-07-05 |
| CN108238892A (en) | 2018-07-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP4279535A3 (en) | Method for preparing polyols | |
| RU2015106856A (en) | METHOD FOR PRODUCING PYRAZOLECARBOXYLIC ACID DERIVATIVES | |
| MX2018014130A (en) | Process and intermediates for the 6,7-alpha-epoxidation of steroid 4,6-dienes. | |
| UA115579C2 (en) | Integrated process for the production of methyl acetate and methanol from synthesis gas and dimethylether | |
| WO2016089758A3 (en) | Organo-1-oxa-4-azonium cyclohexane compounds | |
| IES20180088A2 (en) | Drugs intermediates 2-ethylhexanoic acid synthesis method | |
| MX2016013674A (en) | Improved process of making bioderived propylene glycol. | |
| KR20180096628A (en) | How to make Sony Debug | |
| IES20180086A2 (en) | Drug intermediates isovaleric acid synthesis method | |
| IES20180096A2 (en) | Organic synthesis intermediates m-aminobenzenesulfonic acid synthesis method | |
| IES20180085A2 (en) | Drugs intermediates 1,4-dibromo-2,3-butanediol synthesis method | |
| Li et al. | Concise synthesis of (−)-anisomycin | |
| IES20180079A2 (en) | Medicine intermediates 2,6-dicarboxylic acid pyridine synthesis method | |
| IES20180204A2 (en) | Organic intermediates oxalic acid aldehydes synthesis method | |
| IES20180117A2 (en) | Drug synthesis intermediates p-carboxybenzenesulfonic amide synthesis method | |
| IES20180200A2 (en) | Anti-clavicular spirochete drugs ethyl imidazole synthesis method | |
| IE20180281U1 (en) | Benzoyl peroxide organic intermediates synthesis method | |
| RU2015107017A (en) | Obtaining ioforminol radiopaque agent | |
| IE20180282U1 (en) | Dodecanoyl peroxide organic intermediates synthesis method | |
| IES20180089A2 (en) | Drugs intermediates 2,5-dichlorobenzoic acid synthesis method | |
| IES20180269U1 (en) | Stomach rehabilitation drug intermediates diphenylglycolic acid synthesis method | |
| IES20180267U1 (en) | Aminoquinone drug intermediates tetrachlorobenzoquinone synthesis method | |
| US9481665B2 (en) | Process for preparing PI3K inhibitor buparsilib | |
| IES20180077A2 (en) | Medicine intermediates terephthalic acid synthesis method | |
| IE20180283U1 (en) | O-toluene formamide organic intermediates synthesis method |