IE890232L - Condensed diazepinones - Google Patents

Condensed diazepinones

Info

Publication number
IE890232L
IE890232L IE890232A IE23289A IE890232L IE 890232 L IE890232 L IE 890232L IE 890232 A IE890232 A IE 890232A IE 23289 A IE23289 A IE 23289A IE 890232 L IE890232 L IE 890232L
Authority
IE
Ireland
Prior art keywords
acid addition
addition salts
condensed diazepinones
diazepinones
novel
Prior art date
Application number
IE890232A
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of IE890232L publication Critical patent/IE890232L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Novel condensed diazepinones of the formula <IMAGE> in which R<1> to R<1><0>, A, B, X<1> and X<2> are as defined in Claim 1, their isomers and their acid addition salts, and, in particular for pharmaceutical use, their physiologically tolerable acid addition salts with inorganic or organic acids. The novel compounds have useful properties when used as vagal pacemakers for the treatment of bradycardias and bradyarrhythmias and are obtained by methods known per se. [EP0326066A2]
IE890232A 1988-01-27 1989-01-26 Condensed diazepinones IE890232L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3802334A DE3802334A1 (en) 1988-01-27 1988-01-27 NEW CONDENSED DIAZEPINONE, PROCESS FOR THEIR MANUFACTURE AND MEDICAMENTS CONTAINING THESE COMPOUNDS

Publications (1)

Publication Number Publication Date
IE890232L true IE890232L (en) 1989-07-27

Family

ID=6346078

Family Applications (1)

Application Number Title Priority Date Filing Date
IE890232A IE890232L (en) 1988-01-27 1989-01-26 Condensed diazepinones

Country Status (14)

Country Link
EP (1) EP0326066A3 (en)
JP (1) JPH01233284A (en)
KR (1) KR890011886A (en)
AU (1) AU622887B2 (en)
DD (1) DD283391A5 (en)
DE (1) DE3802334A1 (en)
DK (1) DK33389A (en)
FI (1) FI890380A (en)
HU (1) HU203347B (en)
IE (1) IE890232L (en)
IL (1) IL89098A (en)
NZ (1) NZ227758A (en)
PT (1) PT89540B (en)
ZA (1) ZA89659B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3726908A1 (en) * 1987-08-13 1989-02-23 Thomae Gmbh Dr K NEW CONDENSED DIAZEPINONE, PROCESS FOR THEIR MANUFACTURE AND MEDICAMENTS CONTAINING THESE COMPOUNDS
DE3819444A1 (en) * 1988-06-08 1989-12-14 Thomae Gmbh Dr K NEW CONDENSED DIAZEPINONE, PROCESS FOR THEIR MANUFACTURE AND MEDICAMENTS CONTAINING THESE COMPOUNDS
DD293582A5 (en) * 1989-07-31 1991-09-05 Arzneimittelwerk Dresden,De NEW 5- (OMEGA-AMINOACYL) -5,10-DIHYDRO-11H-DIBENZO / B, E // 1,4 / -DIAZEPINE-11-ONE, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE AS MEDICAMENTS
DE4117123A1 (en) * 1991-05-25 1992-11-26 Dresden Arzneimittel NEW 5-AMINOACYL-5,10-DIHYDRO-11H-DIBENZO / B, E // 1,4 / -DIAZEPIN-11-ONE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210648A (en) * 1977-05-31 1980-07-01 Boehringer Ingelheim Gmbh II-Aminoacyl-5,11-dihydro-6H-pyrido(2,3-B) (1,4)benzodiazepin-6-ones and salts thereof
DE2724501A1 (en) * 1977-05-31 1978-12-21 Thomae Gmbh Dr K NEW, 11-POSITION SUBSTITUTED 5,11-DIHYDRO-6H-PYRIDO SQUARE CLAMP ON 2.3-B SQUARE CLAMP ON SQUARE CLAMP ON 1.4 SQUARE CLAMP ON BENZODIAZEPIN-6- ONE, METHOD FOR THEIR PRODUCTION AND THESE CONNECTIONS DRUG
DE3071581D1 (en) * 1979-08-03 1986-06-05 Byk Gulden Lomberg Chem Fab Substituted tetraazatricyclic compounds, process for their preparation, their use and medicines containing them
IL62792A (en) * 1980-05-07 1985-02-28 Byk Gulden Lomberg Chem Fab Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them
DE3409237A1 (en) * 1984-03-14 1985-09-19 Dr. Karl Thomae Gmbh, 7950 Biberach CONDENSED DIAZEPINONE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
ATE71097T1 (en) * 1985-06-27 1992-01-15 Thomae Gmbh Dr K 5,11-DIHYDRO-6HPYRIDO-(2,3-B>(1,4>BENZODIAZEPIN-6-ONE SUBSTITUTED IN THE 11-POSITION, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THESE COMPOUNDS.
DK0410148T3 (en) * 1989-06-28 1994-08-08 Boehringer Ingelheim Pharma Novel 5,11-dihydro-6H-dipyrido (3,2-b: 2,3-e) - (1,4) diazepin-6-ones and thiones and their use in the prevention or treatment of AIDS

Also Published As

Publication number Publication date
ZA89659B (en) 1990-09-26
AU2886289A (en) 1989-07-27
HUT49351A (en) 1989-09-28
NZ227758A (en) 1991-09-25
DD283391A5 (en) 1990-10-10
DK33389D0 (en) 1989-01-26
DE3802334A1 (en) 1989-08-10
DK33389A (en) 1989-07-28
EP0326066A2 (en) 1989-08-02
FI890380A (en) 1989-07-28
AU622887B2 (en) 1992-04-30
HU203347B (en) 1991-07-29
EP0326066A3 (en) 1991-01-30
FI890380A0 (en) 1989-01-26
KR890011886A (en) 1989-08-23
PT89540B (en) 1994-02-28
JPH01233284A (en) 1989-09-19
IL89098A (en) 1993-01-31
PT89540A (en) 1989-10-04
IL89098A0 (en) 1989-08-15

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