IE890232L - Condensed diazepinones - Google Patents
Condensed diazepinonesInfo
- Publication number
- IE890232L IE890232L IE890232A IE23289A IE890232L IE 890232 L IE890232 L IE 890232L IE 890232 A IE890232 A IE 890232A IE 23289 A IE23289 A IE 23289A IE 890232 L IE890232 L IE 890232L
- Authority
- IE
- Ireland
- Prior art keywords
- acid addition
- addition salts
- condensed diazepinones
- diazepinones
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Novel condensed diazepinones of the formula <IMAGE> in which R<1> to R<1><0>, A, B, X<1> and X<2> are as defined in Claim 1, their isomers and their acid addition salts, and, in particular for pharmaceutical use, their physiologically tolerable acid addition salts with inorganic or organic acids. The novel compounds have useful properties when used as vagal pacemakers for the treatment of bradycardias and bradyarrhythmias and are obtained by methods known per se.
[EP0326066A2]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3802334A DE3802334A1 (en) | 1988-01-27 | 1988-01-27 | NEW CONDENSED DIAZEPINONE, PROCESS FOR THEIR MANUFACTURE AND MEDICAMENTS CONTAINING THESE COMPOUNDS |
Publications (1)
Publication Number | Publication Date |
---|---|
IE890232L true IE890232L (en) | 1989-07-27 |
Family
ID=6346078
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE890232A IE890232L (en) | 1988-01-27 | 1989-01-26 | Condensed diazepinones |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0326066A3 (en) |
JP (1) | JPH01233284A (en) |
KR (1) | KR890011886A (en) |
AU (1) | AU622887B2 (en) |
DD (1) | DD283391A5 (en) |
DE (1) | DE3802334A1 (en) |
DK (1) | DK33389A (en) |
FI (1) | FI890380A (en) |
HU (1) | HU203347B (en) |
IE (1) | IE890232L (en) |
IL (1) | IL89098A (en) |
NZ (1) | NZ227758A (en) |
PT (1) | PT89540B (en) |
ZA (1) | ZA89659B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3726908A1 (en) * | 1987-08-13 | 1989-02-23 | Thomae Gmbh Dr K | NEW CONDENSED DIAZEPINONE, PROCESS FOR THEIR MANUFACTURE AND MEDICAMENTS CONTAINING THESE COMPOUNDS |
DE3819444A1 (en) * | 1988-06-08 | 1989-12-14 | Thomae Gmbh Dr K | NEW CONDENSED DIAZEPINONE, PROCESS FOR THEIR MANUFACTURE AND MEDICAMENTS CONTAINING THESE COMPOUNDS |
DD293582A5 (en) * | 1989-07-31 | 1991-09-05 | Arzneimittelwerk Dresden,De | NEW 5- (OMEGA-AMINOACYL) -5,10-DIHYDRO-11H-DIBENZO / B, E // 1,4 / -DIAZEPINE-11-ONE, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE AS MEDICAMENTS |
DE4117123A1 (en) * | 1991-05-25 | 1992-11-26 | Dresden Arzneimittel | NEW 5-AMINOACYL-5,10-DIHYDRO-11H-DIBENZO / B, E // 1,4 / -DIAZEPIN-11-ONE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4210648A (en) * | 1977-05-31 | 1980-07-01 | Boehringer Ingelheim Gmbh | II-Aminoacyl-5,11-dihydro-6H-pyrido(2,3-B) (1,4)benzodiazepin-6-ones and salts thereof |
DE2724501A1 (en) * | 1977-05-31 | 1978-12-21 | Thomae Gmbh Dr K | NEW, 11-POSITION SUBSTITUTED 5,11-DIHYDRO-6H-PYRIDO SQUARE CLAMP ON 2.3-B SQUARE CLAMP ON SQUARE CLAMP ON 1.4 SQUARE CLAMP ON BENZODIAZEPIN-6- ONE, METHOD FOR THEIR PRODUCTION AND THESE CONNECTIONS DRUG |
DE3071581D1 (en) * | 1979-08-03 | 1986-06-05 | Byk Gulden Lomberg Chem Fab | Substituted tetraazatricyclic compounds, process for their preparation, their use and medicines containing them |
IL62792A (en) * | 1980-05-07 | 1985-02-28 | Byk Gulden Lomberg Chem Fab | Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them |
DE3409237A1 (en) * | 1984-03-14 | 1985-09-19 | Dr. Karl Thomae Gmbh, 7950 Biberach | CONDENSED DIAZEPINONE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
ATE71097T1 (en) * | 1985-06-27 | 1992-01-15 | Thomae Gmbh Dr K | 5,11-DIHYDRO-6HPYRIDO-(2,3-B>(1,4>BENZODIAZEPIN-6-ONE SUBSTITUTED IN THE 11-POSITION, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THESE COMPOUNDS. |
DK0410148T3 (en) * | 1989-06-28 | 1994-08-08 | Boehringer Ingelheim Pharma | Novel 5,11-dihydro-6H-dipyrido (3,2-b: 2,3-e) - (1,4) diazepin-6-ones and thiones and their use in the prevention or treatment of AIDS |
-
1988
- 1988-01-27 DE DE3802334A patent/DE3802334A1/en not_active Withdrawn
-
1989
- 1989-01-24 EP EP19890101158 patent/EP0326066A3/en not_active Withdrawn
- 1989-01-25 DD DD89325222A patent/DD283391A5/en not_active IP Right Cessation
- 1989-01-26 IE IE890232A patent/IE890232L/en unknown
- 1989-01-26 DK DK033389A patent/DK33389A/en not_active Application Discontinuation
- 1989-01-26 FI FI890380A patent/FI890380A/en not_active Application Discontinuation
- 1989-01-26 HU HU89342A patent/HU203347B/en not_active IP Right Cessation
- 1989-01-26 JP JP1017401A patent/JPH01233284A/en active Pending
- 1989-01-26 KR KR1019890000797A patent/KR890011886A/en not_active Application Discontinuation
- 1989-01-26 PT PT89540A patent/PT89540B/en active IP Right Grant
- 1989-01-27 NZ NZ227758A patent/NZ227758A/en unknown
- 1989-01-27 ZA ZA89659A patent/ZA89659B/en unknown
- 1989-01-27 IL IL89098A patent/IL89098A/en unknown
- 1989-01-27 AU AU28862/89A patent/AU622887B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
ZA89659B (en) | 1990-09-26 |
AU2886289A (en) | 1989-07-27 |
HUT49351A (en) | 1989-09-28 |
NZ227758A (en) | 1991-09-25 |
DD283391A5 (en) | 1990-10-10 |
DK33389D0 (en) | 1989-01-26 |
DE3802334A1 (en) | 1989-08-10 |
DK33389A (en) | 1989-07-28 |
EP0326066A2 (en) | 1989-08-02 |
FI890380A (en) | 1989-07-28 |
AU622887B2 (en) | 1992-04-30 |
HU203347B (en) | 1991-07-29 |
EP0326066A3 (en) | 1991-01-30 |
FI890380A0 (en) | 1989-01-26 |
KR890011886A (en) | 1989-08-23 |
PT89540B (en) | 1994-02-28 |
JPH01233284A (en) | 1989-09-19 |
IL89098A (en) | 1993-01-31 |
PT89540A (en) | 1989-10-04 |
IL89098A0 (en) | 1989-08-15 |
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