IE880295L - Alkyl-substitued n-benzopyranyllactams - Google Patents

Alkyl-substitued n-benzopyranyllactams

Info

Publication number
IE880295L
IE880295L IE880295A IE29588A IE880295L IE 880295 L IE880295 L IE 880295L IE 880295 A IE880295 A IE 880295A IE 29588 A IE29588 A IE 29588A IE 880295 L IE880295 L IE 880295L
Authority
IE
Ireland
Prior art keywords
alkyl
benzopyranyllactams
substitued
substituted
represent
Prior art date
Application number
IE880295A
Other versions
IE60932B1 (en
Inventor
Erik Klaus
Dieter Mania
Bernward Schoelkens
Heinrich Englert
Hansjochen Lang
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19873703229 external-priority patent/DE3703229A1/en
Priority claimed from DE19873724876 external-priority patent/DE3724876A1/en
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IE880295L publication Critical patent/IE880295L/en
Publication of IE60932B1 publication Critical patent/IE60932B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

N-Benzopyranyllactams of the formula I <IMAGE> in which R' represents CN, NO2 or SOn-Ar; where n = 1 or 2, Ar represents an aromatic or heteroaromatic system which is unsubstituted or substituted and p represents 1 or 2, R<2> represents H, OH, (C1-C2)-alkoxy, (C1-C2)-alkyl, halogen or NR<5>R<6>, where R<5> and R<6> are identical or different and represent H, (C1-C2)-alkyl or (C1-C2)-alkylcarbonyl, R<3> and R<4> are identical or different and represent alkyl having 1-4 C atoms, the abovementioned meanings of R<1> and R<2> can also be exchanged, X represents a chain (CH2)m, which is substituted by at least 1 and at most 2m-1 (C1-C2)-alkyl groups, and can also be interrupted by a heteroatom Y having the meaning O, NR<7> or S and R<7> denotes H or (C1-C4)-alkyl and m represents 2, 3 or 4, are described. They have hypotensive activity and/or ureter-relaxing activity. [EP0277611A2]
IE29588A 1987-02-04 1988-02-03 Alkyl-substituted N-benzopyranyllactams, a process for their preparation, their use, and pharmaceutical preparations based on these compounds IE60932B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19873703229 DE3703229A1 (en) 1987-02-04 1987-02-04 Alkyl-substituted N-benzopyranyl lactams, processes for their preparation, their use and pharmaceutical preparations based on these compounds
DE19873724876 DE3724876A1 (en) 1987-07-28 1987-07-28 Alkyl-substituted N-benzopyranyllactams, processes for their preparation, their use and pharmaceutical preparations based on these compounds

Publications (2)

Publication Number Publication Date
IE880295L true IE880295L (en) 1988-08-04
IE60932B1 IE60932B1 (en) 1994-09-07

Family

ID=25852153

Family Applications (1)

Application Number Title Priority Date Filing Date
IE29588A IE60932B1 (en) 1987-02-04 1988-02-03 Alkyl-substituted N-benzopyranyllactams, a process for their preparation, their use, and pharmaceutical preparations based on these compounds

Country Status (14)

Country Link
EP (1) EP0277611B1 (en)
KR (1) KR880009957A (en)
AU (1) AU604089B2 (en)
DE (1) DE3881714D1 (en)
DK (1) DK167440B1 (en)
ES (1) ES2058148T3 (en)
FI (1) FI92064C (en)
HU (1) HU207729B (en)
IE (1) IE60932B1 (en)
IL (1) IL85289A (en)
NO (1) NO169964C (en)
NZ (1) NZ223384A (en)
PH (1) PH24836A (en)
PT (1) PT86691B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3703227A1 (en) * 1987-02-04 1988-08-18 Hoechst Ag SUBSTITUTED 3,4-DIHYDRO-2H-BENZOPYRANES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS
GB8800199D0 (en) * 1988-01-06 1988-02-10 Beecham Group Plc Pharmaceutical preparation
DE3824446A1 (en) * 1988-07-19 1990-01-25 Hoechst Ag USE OF SUBSTITUTED 3,4-DIHYDRO-2H-BENZOPYRANE AS A MEDICINE AGAINST OBSTRUCTIVE FUNCTIONAL DISORDERS OF THE LUNG AND / OR DISORDERS OF THE LEADING URINE PATHS
DE3827532A1 (en) * 1988-08-13 1990-03-01 Hoechst Ag 6-AROYL-SUBSTITUTED 3,4-DIHYDRO-2H-BENZOPYRANES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS
FR2637896B1 (en) * 1988-10-17 1990-11-30 Adir NOVEL AMINO CHROMANOL DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
DE3901720A1 (en) * 1989-01-21 1990-07-26 Hoechst Ag SUBSTITUTED BENZO (B) PYRANS, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS
US5104890A (en) * 1989-03-28 1992-04-14 Fujisawa Pharmaceutical Company, Ltd. Benzopyran derivatives and processes for preparation thereof
IE63935B1 (en) * 1989-06-27 1995-06-28 Chem Pharm Forsch Gmbh Novel thienopyran derivatives a process for their preparation and their use
GB8924373D0 (en) * 1989-10-30 1989-12-20 Beecham Group Plc Novel compounds
AU651105B2 (en) * 1990-06-18 1994-07-14 E.R. Squibb & Sons, Inc. Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents
HUT72741A (en) * 1992-12-19 1996-05-28 Alkaloida Vegyeszeti Gyar Method for producing benzopyrane derivatives and pharmaceutical compositions containing them
GB9316111D0 (en) * 1993-08-04 1993-09-22 Pfizer Ltd Benzopyrans

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2107706A (en) * 1981-09-25 1983-05-05 Beecham Group Plc Benzopyrans
DE3364734D1 (en) * 1982-10-19 1986-08-28 Beecham Group Plc Novel chromans and chromenes
GB8308064D0 (en) * 1983-03-24 1983-05-05 Beecham Group Plc Active compounds
GB8308062D0 (en) * 1983-03-24 1983-05-05 Beecham Group Plc Active compounds
GB8419516D0 (en) * 1984-07-31 1984-09-05 Beecham Group Plc Treatment
DE3726261A1 (en) * 1986-12-23 1988-07-07 Merck Patent Gmbh CHROME DERIVATIVES
DE3703227A1 (en) * 1987-02-04 1988-08-18 Hoechst Ag SUBSTITUTED 3,4-DIHYDRO-2H-BENZOPYRANES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS

Also Published As

Publication number Publication date
HU207729B (en) 1993-05-28
PT86691B (en) 1992-04-30
FI92064B (en) 1994-06-15
EP0277611A3 (en) 1990-04-25
IL85289A (en) 1994-04-12
AU1122788A (en) 1988-09-08
PT86691A (en) 1988-03-01
HUT50165A (en) 1989-12-28
EP0277611A2 (en) 1988-08-10
DK167440B1 (en) 1993-11-01
EP0277611B1 (en) 1993-06-16
AU604089B2 (en) 1990-12-06
IL85289A0 (en) 1988-07-31
IE60932B1 (en) 1994-09-07
FI92064C (en) 1994-09-26
FI880468A (en) 1988-08-05
FI880468A0 (en) 1988-02-02
PH24836A (en) 1990-10-30
NZ223384A (en) 1989-11-28
NO880474L (en) 1988-08-05
DK55188A (en) 1988-08-05
NO880474D0 (en) 1988-02-03
KR880009957A (en) 1988-10-06
DK55188D0 (en) 1988-02-03
DE3881714D1 (en) 1993-07-22
NO169964B (en) 1992-05-18
NO169964C (en) 1992-08-26
ES2058148T3 (en) 1994-11-01

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Legal Events

Date Code Title Description
MM4A Patent lapsed