IE781780L - Production of 4-aryl-quinazolin-2-(1h)-ones - Google Patents

Production of 4-aryl-quinazolin-2-(1h)-ones

Info

Publication number
IE781780L
IE781780L IE781780A IE178078A IE781780L IE 781780 L IE781780 L IE 781780L IE 781780 A IE781780 A IE 781780A IE 178078 A IE178078 A IE 178078A IE 781780 L IE781780 L IE 781780L
Authority
IE
Ireland
Prior art keywords
aryl
quinazolin
ones
production
gb2003873a
Prior art date
Application number
IE781780A
Other versions
IE47184B1 (en
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of IE781780L publication Critical patent/IE781780L/en
Publication of IE47184B1 publication Critical patent/IE47184B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/80—Oxygen atoms
    • C07D239/82—Oxygen atoms with an aryl radical attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A process for producing 4-aryl- quinazolin-2(1H)-ones comprises dehydrating a corresponding 4-aryl- 5,6,7,8-tetrahydro-2(1H)- quinazolinone with sulphur in an inert organic solvent, in the presence of an inorganic metal oxide, hydroxide or salt (other than of magnesium, aluminium or an alkali metal), which forms a metal sulphide under the reaction conditions. The products are known as anti- inflammatory agents. [GB2003873A]
IE1780/78A 1977-09-06 1978-09-04 Improvements in or relating to organic compounds IE47184B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83041177A 1977-09-06 1977-09-06

Publications (2)

Publication Number Publication Date
IE781780L true IE781780L (en) 1979-03-06
IE47184B1 IE47184B1 (en) 1984-01-11

Family

ID=25256956

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1780/78A IE47184B1 (en) 1977-09-06 1978-09-04 Improvements in or relating to organic compounds

Country Status (28)

Country Link
JP (1) JPS5455583A (en)
AR (1) AR228235A1 (en)
AT (1) AT376211B (en)
AU (1) AU523728B2 (en)
BE (1) BE870185A (en)
CA (1) CA1111847A (en)
CH (1) CH642638A5 (en)
DD (1) DD138657A5 (en)
DE (1) DE2837403A1 (en)
DK (1) DK144999C (en)
ES (1) ES473103A1 (en)
FI (1) FI66362C (en)
FR (1) FR2401917A1 (en)
GB (1) GB2003873B (en)
GR (1) GR73605B (en)
HU (1) HU183018B (en)
IE (1) IE47184B1 (en)
IL (1) IL55492A (en)
IT (1) IT1106289B (en)
NL (1) NL7808981A (en)
NO (1) NO782945L (en)
NZ (1) NZ188329A (en)
PL (1) PL114207B1 (en)
PT (1) PT68505A (en)
SE (1) SE7809098L (en)
SU (1) SU900810A3 (en)
YU (1) YU211078A (en)
ZA (1) ZA785061B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH637114A5 (en) * 1978-08-16 1983-07-15 Sandoz Ag 2- (N-CARBOALKOXYAMINO) -BENZOPHENONE, THEIR PRODUCTION AND USE.
CH645362A5 (en) * 1979-07-05 1984-09-28 Sandoz Ag METHOD FOR PRODUCING 4-PHENYL-2 (1H) -QUINAZOLINONES.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE785937A (en) * 1971-07-08 1973-01-08 Sandoz Sa NEW DERIVATIVES OF QUINAZOLINE, THEIR PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS

Also Published As

Publication number Publication date
HU183018B (en) 1984-04-28
JPS5455583A (en) 1979-05-02
GB2003873A (en) 1979-03-21
YU211078A (en) 1982-10-31
SE7809098L (en) 1979-03-07
DK144999C (en) 1982-12-13
IT1106289B (en) 1985-11-11
NZ188329A (en) 1981-05-15
DE2837403A1 (en) 1979-03-08
NL7808981A (en) 1979-03-08
FI66362B (en) 1984-06-29
FI782619A (en) 1979-03-07
FR2401917A1 (en) 1979-03-30
ATA639978A (en) 1984-03-15
AR228235A1 (en) 1983-02-15
BE870185A (en) 1979-03-05
FI66362C (en) 1984-10-10
IL55492A0 (en) 1978-12-17
GR73605B (en) 1984-03-26
PL114207B1 (en) 1981-01-31
PT68505A (en) 1978-10-01
ES473103A1 (en) 1979-04-01
IL55492A (en) 1982-08-31
DK382078A (en) 1979-03-07
CA1111847A (en) 1981-11-03
GB2003873B (en) 1982-03-10
PL209423A1 (en) 1979-06-04
NO782945L (en) 1979-03-07
DD138657A5 (en) 1979-11-14
CH642638A5 (en) 1984-04-30
IT7850936A0 (en) 1978-09-01
IE47184B1 (en) 1984-01-11
DK144999B (en) 1982-07-26
ZA785061B (en) 1980-04-30
AU3957178A (en) 1980-03-13
FR2401917B1 (en) 1982-12-17
AT376211B (en) 1984-10-25
AU523728B2 (en) 1982-08-12
SU900810A3 (en) 1982-01-23

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