IE43797L - Esters of indole-derived aminoalcohols. - Google Patents
Esters of indole-derived aminoalcohols.Info
- Publication number
- IE43797L IE43797L IE761791A IE179176A IE43797L IE 43797 L IE43797 L IE 43797L IE 761791 A IE761791 A IE 761791A IE 179176 A IE179176 A IE 179176A IE 43797 L IE43797 L IE 43797L
- Authority
- IE
- Ireland
- Prior art keywords
- phenyl
- methyl
- aminoalcohols
- indole
- esters
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
This invention provides compounds of formula I, I wherein R1 is phenyl; phenyl monosubstituted with fluorine; phenyl mono- or disubstituted with chlorine; phenyl mono-, di- or trisubstituted with methyl or methoxy, secondary 1-phenoxyalkyl, the secondary alkyl residue of which is of 3 to 5 carbon atoms and in which the phenyl residue is unsubstituted or monosubstituted with chlorine, and either R2 is hydrogen, and R3 is methyl, or R2 is methyl and R3 is hydrogen or methyl, which are useful, for example, for treating coronary conditions. (From US4434176 A) [FR2320743A2]
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IE2297/79A IE43798B1 (en) | 1975-08-15 | 1976-08-13 | An ester of an indole-derived aminoalcohol |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1071475 | 1975-08-15 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE43797L true IE43797L (en) | 1977-02-15 |
| IE43797B1 IE43797B1 (en) | 1981-06-03 |
Family
ID=4366041
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1791/76A IE43797B1 (en) | 1975-08-15 | 1976-08-13 | Esters of indole-derived amino alcohols |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US4434176A (en) |
| JP (2) | JPS5223073A (en) |
| AT (1) | AT363070B (en) |
| AU (1) | AU505719B2 (en) |
| BE (1) | BE845197R (en) |
| CA (1) | CA1080720A (en) |
| CY (1) | CY1225A (en) |
| DE (1) | DE2635209C2 (en) |
| DK (1) | DK152120C (en) |
| ES (1) | ES450681A1 (en) |
| FI (1) | FI63751C (en) |
| FR (1) | FR2320743A2 (en) |
| GB (2) | GB1575509A (en) |
| HK (1) | HK35884A (en) |
| IE (1) | IE43797B1 (en) |
| IL (2) | IL50263A (en) |
| KE (1) | KE3404A (en) |
| MY (1) | MY8500135A (en) |
| NL (2) | NL176362C (en) |
| NO (1) | NO762735L (en) |
| NZ (1) | NZ181764A (en) |
| PH (1) | PH13356A (en) |
| PT (1) | PT65477B (en) |
| SE (1) | SE414633B (en) |
| SG (1) | SG84883G (en) |
| SU (1) | SU649313A3 (en) |
| YU (1) | YU198876A (en) |
| ZA (1) | ZA764883B (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2830211A1 (en) * | 1977-07-21 | 1979-02-01 | Sandoz Ag | SUBSTITUTED INDOL DERIVATIVES, THEIR PRODUCTION AND USE |
| JPS58106499A (en) * | 1981-12-19 | 1983-06-24 | 株式会社東芝 | Fuel exchanging device of fast breeder |
| NL8600137A (en) * | 1985-02-05 | 1986-09-01 | Sandoz Ag | PHARMACEUTICAL PREPARATIONS CONTAINING, WHEN DESIRED, COMBINED WITH 3-AMINOPROPOXYINDOLS DIURETICALLY AND METHODS FOR USING THESE PREPARATIONS. |
| US5174210A (en) * | 1990-04-27 | 1992-12-29 | Heidelberger Druckmaschinen Aktiengesellschaft | Preparation of the inking unit of a printing press for a change of printing job |
| JPH09508378A (en) * | 1994-01-28 | 1997-08-26 | シーエーエル・インターナショナル・リミテッド | Pharmaceutical product containing the esterifiable β-blocker salicylate |
| CA2753318A1 (en) * | 2003-05-30 | 2004-12-09 | Ranbaxy Laboratories Limited | Substituted pyrrole derivatives |
| US8026377B2 (en) * | 2005-11-08 | 2011-09-27 | Ranbaxy Laboratories, Limited | Process for (3R, 5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid hemi calcium salt |
| WO2008020314A2 (en) * | 2006-03-14 | 2008-02-21 | Ranbaxy Laboratories Limited | Statin stabilizing dosage formulations |
| TW200811101A (en) * | 2006-07-14 | 2008-03-01 | Ranbaxy Lab Ltd | Polymorphic forms of an HMG-CoA reductase inhibitor and uses thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH532040A (en) * | 1970-03-24 | 1972-12-31 | Sandoz Ag | Process for the production of new indole derivatives |
| US3751429A (en) * | 1970-03-24 | 1973-08-07 | Sandoz Ltd | 4-(3-amino-2-substituted propoxy)indole derivatives |
| SE375771B (en) * | 1970-09-30 | 1975-04-28 | Sandoz Ag | |
| CH545783A (en) * | 1971-01-07 | 1974-02-15 | Novel indole derivs - prepn by reacting 4-(2-hydroxy-3-isopropylaminopropoxy) indoles and acid anhy-drides | |
| CH545784A (en) * | 1971-01-07 | 1974-02-15 | Beta blocking and anti-arrhythmic indole derivs - prepd by catalytic de-benzylation of 4-(3-benzyl aminopropoxy) indoles |
-
1976
- 1976-08-05 DE DE2635209A patent/DE2635209C2/en not_active Expired
- 1976-08-06 NO NO762735A patent/NO762735L/no unknown
- 1976-08-06 FI FI762258A patent/FI63751C/en not_active IP Right Cessation
- 1976-08-06 SE SE7608865A patent/SE414633B/en unknown
- 1976-08-06 DK DK357576A patent/DK152120C/en not_active IP Right Cessation
- 1976-08-11 NL NLAANVRAGE7608902,A patent/NL176362C/en active Protection Beyond IP Right Term
- 1976-08-12 YU YU01988/76A patent/YU198876A/en unknown
- 1976-08-12 FR FR7624659A patent/FR2320743A2/en active Granted
- 1976-08-13 BE BE169821A patent/BE845197R/en active
- 1976-08-13 IL IL50263A patent/IL50263A/en unknown
- 1976-08-13 NZ NZ181764A patent/NZ181764A/en unknown
- 1976-08-13 AU AU16841/76A patent/AU505719B2/en not_active Expired
- 1976-08-13 ES ES450681A patent/ES450681A1/en not_active Expired
- 1976-08-13 SU SU762388420A patent/SU649313A3/en active
- 1976-08-13 CA CA259,050A patent/CA1080720A/en not_active Expired
- 1976-08-13 PT PT65477A patent/PT65477B/en unknown
- 1976-08-13 IE IE1791/76A patent/IE43797B1/en not_active IP Right Cessation
- 1976-08-13 GB GB33753/76A patent/GB1575509A/en not_active Expired
- 1976-08-13 AT AT0602576A patent/AT363070B/en not_active IP Right Cessation
- 1976-08-13 PH PH18788A patent/PH13356A/en unknown
- 1976-08-13 GB GB13931/79A patent/GB1575510A/en not_active Expired
- 1976-08-13 CY CY1125A patent/CY1225A/en unknown
- 1976-08-13 ZA ZA00764883A patent/ZA764883B/en unknown
- 1976-08-14 JP JP51096629A patent/JPS5223073A/en active Granted
-
1979
- 1979-09-03 IL IL58163A patent/IL58163A0/en unknown
-
1980
- 1980-05-23 JP JP6800480A patent/JPS5649318A/en active Pending
-
1982
- 1982-05-06 US US06/375,369 patent/US4434176A/en not_active Expired - Lifetime
-
1983
- 1983-12-29 SG SG848/83A patent/SG84883G/en unknown
-
1984
- 1984-04-19 KE KE3404A patent/KE3404A/en unknown
- 1984-04-26 HK HK358/84A patent/HK35884A/en unknown
-
1985
- 1985-12-30 MY MY135/85A patent/MY8500135A/en unknown
-
1993
- 1993-07-02 NL NL930134C patent/NL930134I2/en unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed | ||
| HK2 | Errata: patent lapsed |