IE41564L - Ergot peptide alkaloids - Google Patents
Ergot peptide alkaloidsInfo
- Publication number
- IE41564L IE41564L IE751375A IE137575A IE41564L IE 41564 L IE41564 L IE 41564L IE 751375 A IE751375 A IE 751375A IE 137575 A IE137575 A IE 137575A IE 41564 L IE41564 L IE 41564L
- Authority
- IE
- Ireland
- Prior art keywords
- acid
- june
- prepared
- dihydrolysergic
- ester
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/02—Ergot alkaloids of the cyclic peptide type
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
1499420 9,10-Dihydroergopeptine derivatives SANDOZ Ltd 16 June 1975 [21 June 1974] 25527/75 Heading C2C Novel compounds of the Formula I wherein R 1 is C 2-5 alkyl and R 2 is methyl or ethyl and acid addition salts thereof may be prepared by condensing a functional derivative of a compound II with an acid addition salt of a compound III 6 - Nor - 6 - isopropyl - 9,10 - dihydrolysergic acid is prepared by N-alkylation of 6-nor-9,10- dihydrolysergic acid methyl ester, followed by saponification of the ester. Its acid choride is formed in situ using oxalyl chloride. Pharmaceutical compositions of the compounds I with the usual excipients show vasoconstricter activity.
[GB1499420A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH853374A CH602767A5 (en) | 1974-06-21 | 1974-06-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE41564L true IE41564L (en) | 1975-12-21 |
| IE41564B1 IE41564B1 (en) | 1980-01-30 |
Family
ID=4341635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1375/75A IE41564B1 (en) | 1974-06-21 | 1975-06-19 | Ergot peptide alkaloids |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS5113798A (en) |
| AT (1) | AT356292B (en) |
| AU (1) | AU503060B2 (en) |
| BE (1) | BE830441A (en) |
| CA (1) | CA1057285A (en) |
| DD (1) | DD118088A5 (en) |
| DE (1) | DE2525962A1 (en) |
| DK (1) | DK140670B (en) |
| ES (1) | ES438704A1 (en) |
| FI (1) | FI751753A (en) |
| FR (1) | FR2275212A1 (en) |
| GB (1) | GB1499420A (en) |
| HU (1) | HU169390B (en) |
| IE (1) | IE41564B1 (en) |
| IL (1) | IL47522A (en) |
| NL (1) | NL7507177A (en) |
| NO (1) | NO752109L (en) |
| PH (1) | PH13361A (en) |
| SE (1) | SE7506758L (en) |
| YU (1) | YU157375A (en) |
| ZA (1) | ZA753967B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH601321A5 (en) * | 1975-01-06 | 1978-07-14 | Sandoz Ag | |
| CH619468A5 (en) * | 1976-01-12 | 1980-09-30 | Sandoz Ag | |
| GB0409785D0 (en) | 2004-04-30 | 2004-06-09 | Resolution Chemicals Ltd | Preparation of cabergoline |
| US7339060B2 (en) | 2005-03-23 | 2008-03-04 | Resolution Chemicals, Ltd. | Preparation of cabergoline |
| GB0505965D0 (en) | 2005-03-23 | 2005-04-27 | Resolution Chemicals Ltd | Preparation of cabergoline |
-
1975
- 1975-06-11 DE DE19752525962 patent/DE2525962A1/en not_active Withdrawn
- 1975-06-12 DK DK266475AA patent/DK140670B/en unknown
- 1975-06-12 FI FI751753A patent/FI751753A/fi unknown
- 1975-06-12 SE SE7506758A patent/SE7506758L/en unknown
- 1975-06-13 NO NO752109A patent/NO752109L/no unknown
- 1975-06-16 GB GB25527/75A patent/GB1499420A/en not_active Expired
- 1975-06-17 NL NL7507177A patent/NL7507177A/en not_active Application Discontinuation
- 1975-06-17 FR FR7518879A patent/FR2275212A1/en active Granted
- 1975-06-17 PH PH17276A patent/PH13361A/en unknown
- 1975-06-19 ES ES438704A patent/ES438704A1/en not_active Expired
- 1975-06-19 YU YU01573/75A patent/YU157375A/en unknown
- 1975-06-19 IL IL47522A patent/IL47522A/en unknown
- 1975-06-19 BE BE157509A patent/BE830441A/en unknown
- 1975-06-19 DD DD186767A patent/DD118088A5/xx unknown
- 1975-06-19 AU AU82273/75A patent/AU503060B2/en not_active Expired
- 1975-06-19 IE IE1375/75A patent/IE41564B1/en unknown
- 1975-06-19 HU HUSA2806A patent/HU169390B/hu unknown
- 1975-06-20 AT AT473575A patent/AT356292B/en not_active IP Right Cessation
- 1975-06-20 JP JP50074583A patent/JPS5113798A/ja active Pending
- 1975-06-20 ZA ZA3967A patent/ZA753967B/en unknown
- 1975-06-20 CA CA229,783A patent/CA1057285A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5113798A (en) | 1976-02-03 |
| PH13361A (en) | 1980-03-20 |
| HU169390B (en) | 1976-11-28 |
| DK140670C (en) | 1980-03-17 |
| YU157375A (en) | 1982-05-31 |
| NO752109L (en) | 1975-12-23 |
| NL7507177A (en) | 1975-12-23 |
| ZA753967B (en) | 1977-01-26 |
| CA1057285A (en) | 1979-06-26 |
| ES438704A1 (en) | 1977-06-01 |
| AU8227375A (en) | 1976-12-23 |
| DD118088A5 (en) | 1976-02-12 |
| SE7506758L (en) | 1975-12-22 |
| DK266475A (en) | 1975-12-22 |
| GB1499420A (en) | 1978-02-01 |
| AU503060B2 (en) | 1979-08-23 |
| AT356292B (en) | 1980-04-25 |
| ATA473575A (en) | 1979-09-15 |
| IE41564B1 (en) | 1980-01-30 |
| FR2275212B1 (en) | 1979-08-10 |
| IL47522A0 (en) | 1975-08-31 |
| BE830441A (en) | 1975-12-19 |
| FR2275212A1 (en) | 1976-01-16 |
| FI751753A (en) | 1975-12-22 |
| DE2525962A1 (en) | 1976-01-08 |
| IL47522A (en) | 1977-12-30 |
| DK140670B (en) | 1979-10-22 |
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