IE38917B1 - Isoquinoline derivatives and process for their manufactur - Google Patents
Isoquinoline derivatives and process for their manufacturInfo
- Publication number
- IE38917B1 IE38917B1 IE00358/74A IE35874A IE38917B1 IE 38917 B1 IE38917 B1 IE 38917B1 IE 00358/74 A IE00358/74 A IE 00358/74A IE 35874 A IE35874 A IE 35874A IE 38917 B1 IE38917 B1 IE 38917B1
- Authority
- IE
- Ireland
- Prior art keywords
- feb
- therapeutic compositions
- division
- agents
- manufactur
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
1457186 Therapeutic compositions HOECHST AG 22 Feb 1974 [24 Feb 1973] 8171/74 Heading A5B [Also in Division C2] Therapeutic compositions having hypolipaemic and (in some cases) hypoglycaemic activity and which are preferably administered orally, comprise (with certain exclusions: see Division C2) compounds of formula wherein X is O or S; R<SP>1</SP> is H, C 1-6 alkyl or Ph; R<SP>2</SP> is H, or R<SP>1</SP>-R<SP>2</SP> forms with the ring 4-C atom a carbocyclic 5- or 6-membered ring; R<SP>3</SP>, R<SP>4</SP>, R<SP>5</SP> are each H, halogen or NO 2 ; and R<SP>6</SP>, R<SP>7</SP> are each H or C 1-4 alkoxy. Other pharmaceutically active substances which may be present are antidiabetics such as glycodiazin, tolbutamide, glibenclamide, phenformin, buformin and metformin; circulatory agents such as chromonar and prenylamine; hypotensives such as reserpin, alpha-methyldopa and clonidines; other hypolipaemics; geriatric agents; psycho-pharmaceuticals such as chlordiazepoxide, diazepan or meprobamate; and vitamins.
[GB1457186A]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19732309367 DE2309367A1 (en) | 1973-02-24 | 1973-02-24 | 1,4-DIHYDRO-4-H-ISOCHINOLINE DERIVATIVES AND THE PROCESS FOR THEIR PRODUCTION |
Publications (2)
Publication Number | Publication Date |
---|---|
IE38917L IE38917L (en) | 1974-08-24 |
IE38917B1 true IE38917B1 (en) | 1978-06-21 |
Family
ID=5873034
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE00358/74A IE38917B1 (en) | 1973-02-24 | 1974-02-22 | Isoquinoline derivatives and process for their manufactur |
Country Status (13)
Country | Link |
---|---|
JP (1) | JPS49117475A (en) |
AT (1) | ATA146874A (en) |
AU (1) | AU6593074A (en) |
BE (1) | BE811528A (en) |
CA (1) | CA1016173A (en) |
DD (1) | DD114408A5 (en) |
DE (1) | DE2309367A1 (en) |
FR (1) | FR2218892B1 (en) |
GB (1) | GB1457186A (en) |
IE (1) | IE38917B1 (en) |
IL (1) | IL44208A0 (en) |
NL (1) | NL7402259A (en) |
ZA (1) | ZA741172B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8328052D0 (en) * | 1983-10-20 | 1983-11-23 | Beecham Group Plc | Compounds |
CN111039867A (en) * | 2019-12-11 | 2020-04-21 | 四川大学 | Green synthesis method of 3, 4-disubstituted isoquinoline derivative promoted by room-temperature illumination |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1354246A (en) * | 1971-05-27 | 1974-06-05 | Egyt Gyogyszervegyeszeti Gyar | 1,4-dihydro-3-2h-isoquinoline derivatives and a process for the preparation thereof |
-
1973
- 1973-02-24 DE DE19732309367 patent/DE2309367A1/en active Pending
-
1974
- 1974-02-14 IL IL44208A patent/IL44208A0/en unknown
- 1974-02-18 CA CA192,842A patent/CA1016173A/en not_active Expired
- 1974-02-19 NL NL7402259A patent/NL7402259A/xx unknown
- 1974-02-20 DD DD176704A patent/DD114408A5/xx unknown
- 1974-02-22 IE IE00358/74A patent/IE38917B1/en unknown
- 1974-02-22 AT AT146874A patent/ATA146874A/en not_active Application Discontinuation
- 1974-02-22 ZA ZA00741172A patent/ZA741172B/en unknown
- 1974-02-22 FR FR7406209A patent/FR2218892B1/fr not_active Expired
- 1974-02-22 GB GB817174A patent/GB1457186A/en not_active Expired
- 1974-02-23 JP JP49021064A patent/JPS49117475A/ja active Pending
- 1974-02-25 BE BE141348A patent/BE811528A/en unknown
- 1974-02-25 AU AU65930/74A patent/AU6593074A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ATA146874A (en) | 1977-08-15 |
BE811528A (en) | 1974-08-26 |
DE2309367A1 (en) | 1974-09-05 |
AU6593074A (en) | 1975-08-28 |
FR2218892B1 (en) | 1978-01-06 |
NL7402259A (en) | 1974-08-27 |
JPS49117475A (en) | 1974-11-09 |
CA1016173A (en) | 1977-08-23 |
GB1457186A (en) | 1976-12-01 |
IE38917L (en) | 1974-08-24 |
ZA741172B (en) | 1975-01-29 |
FR2218892A1 (en) | 1974-09-20 |
IL44208A0 (en) | 1974-05-16 |
DD114408A5 (en) | 1975-08-05 |
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