HUT46931A - Process for producing dipeptides containing n-terminal 1-carboxy-alkyl groups - Google Patents

Process for producing dipeptides containing n-terminal 1-carboxy-alkyl groups

Info

Publication number
HUT46931A
HUT46931A HU425286A HU425286A HUT46931A HU T46931 A HUT46931 A HU T46931A HU 425286 A HU425286 A HU 425286A HU 425286 A HU425286 A HU 425286A HU T46931 A HUT46931 A HU T46931A
Authority
HU
Hungary
Prior art keywords
carboxy
terminal
acid
alkyl
adduct
Prior art date
Application number
HU425286A
Other languages
Hungarian (hu)
Other versions
HU197587B (en
Inventor
Janos Fischer
Bela Stefko
Laszlo Dobay
Geza Ivanyi
Csaba Loerincz
Tamas Fodor
Bela Szarvady
Tamas Ueberhardt
Lajos Kovacs
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Priority to HU425286A priority Critical patent/HU197587B/en
Publication of HUT46931A publication Critical patent/HUT46931A/en
Publication of HU197587B publication Critical patent/HU197587B/en

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Abstract

Dipeptides contg. N-terminal-carboxy-alkyl gps. of gluerol formula (1), as N-(1(S)-carboxy 3-phenyl-propyl)-S-alanyl (S)proline-derivs., where R = a hydrogen atom or a known peptide chemistry protective gp.; R1 = 1-4C alkyl gp. or such an alkyl-amino gp. which is protected as in this case - are prepd. from a di:peptide of formula (111) where R and R1 are as before and from 4-phenyl-4-oxo-butenoic acid-benzyl ester. Cpds. (11) is separated from its soln. in the reaction mix, as an acid adduct salt. (R and R1 unchanged). The acid adduct, in this case, is formed with a strong acid. - The product may be liberated from the adduct or used as an acid adduct or as a basic salt.
HU425286A 1986-10-13 1986-10-13 Process for producing dipeptides comprising 1-carboxy-alkyl group on its n-terminal HU197587B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HU425286A HU197587B (en) 1986-10-13 1986-10-13 Process for producing dipeptides comprising 1-carboxy-alkyl group on its n-terminal

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU425286A HU197587B (en) 1986-10-13 1986-10-13 Process for producing dipeptides comprising 1-carboxy-alkyl group on its n-terminal

Publications (2)

Publication Number Publication Date
HUT46931A true HUT46931A (en) 1988-12-28
HU197587B HU197587B (en) 1989-04-28

Family

ID=10967457

Family Applications (1)

Application Number Title Priority Date Filing Date
HU425286A HU197587B (en) 1986-10-13 1986-10-13 Process for producing dipeptides comprising 1-carboxy-alkyl group on its n-terminal

Country Status (1)

Country Link
HU (1) HU197587B (en)

Also Published As

Publication number Publication date
HU197587B (en) 1989-04-28

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee