HUT40644A - Process for production of new derivatives of 1,4-dihydropiridin-3,5-dicarbonic acid esther and medical preparatives containing thereof - Google Patents

Process for production of new derivatives of 1,4-dihydropiridin-3,5-dicarbonic acid esther and medical preparatives containing thereof

Info

Publication number
HUT40644A
HUT40644A HU853611A HU361185A HUT40644A HU T40644 A HUT40644 A HU T40644A HU 853611 A HU853611 A HU 853611A HU 361185 A HU361185 A HU 361185A HU T40644 A HUT40644 A HU T40644A
Authority
HU
Hungary
Prior art keywords
dihydropiridin
production
new derivatives
dicarbonic acid
preparatives containing
Prior art date
Application number
HU853611A
Other languages
Hungarian (hu)
Other versions
HU195500B (en
Inventor
Noboru Shimizu
Hiroyuki Ishiwata
Hiroshi Ishihama
Tomio Ochta
Yasumi Uchida
Original Assignee
Kowa Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co filed Critical Kowa Co
Publication of HUT40644A publication Critical patent/HUT40644A/en
Publication of HU195500B publication Critical patent/HU195500B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU853611A 1984-08-14 1985-08-12 Process for the production of new derivatives of 1,4-dihydropiridin-3,5-dicarbonic acid esther and medical preparatives containing them as active agents HU195500B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59169588A JPS6147477A (en) 1984-08-14 1984-08-14 Novel 1,4-dihydropyridine-3,5-dicarboxylic acid ester derivative
PCT/JP1985/000449 WO1986001206A1 (en) 1984-08-14 1985-08-12 Novel 1,4-dihidropyridine-3,5-dicarboxylate derivatives

Publications (2)

Publication Number Publication Date
HUT40644A true HUT40644A (en) 1987-01-28
HU195500B HU195500B (en) 1988-05-30

Family

ID=15889265

Family Applications (1)

Application Number Title Priority Date Filing Date
HU853611A HU195500B (en) 1984-08-14 1985-08-12 Process for the production of new derivatives of 1,4-dihydropiridin-3,5-dicarbonic acid esther and medical preparatives containing them as active agents

Country Status (10)

Country Link
US (1) US4737506A (en)
EP (1) EP0190364A4 (en)
JP (1) JPS6147477A (en)
KR (1) KR860700252A (en)
AU (1) AU577152B2 (en)
DK (1) DK165686A (en)
ES (3) ES8707185A1 (en)
HU (1) HU195500B (en)
NO (1) NO861422L (en)
WO (1) WO1986001206A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5091191A (en) * 1988-02-03 1992-02-25 Yoshitomi Pharmaceutical Industries, Ltd. Pharmaceutical composition with improved dissolution property
DE3991589T1 (en) * 1989-02-17 1991-02-21 Inst Organicheskogo Sinteza Ak BASIC SALTS OF 2- (2,6-DIEMTHYL-3,5-DIAETHOXYKARBOONYL-1,4-DIHYDROPYRIDINE-4-KARBOXAMIDO) AETHANESULPHONIC ACID AND METHOD FOR THE PRODUCTION THEREOF
DK0448091T3 (en) * 1990-03-23 1999-05-03 Yoshitomi Pharmaceutical Pharmaceutical preparation containing a poorly water-soluble drug
DE4233347A1 (en) * 1992-10-05 1994-04-07 Bayer Ag Dihydropyridine alkoxy and alkylamino aroyl esters
CN1159009C (en) * 1995-12-27 2004-07-28 三菱制药株式会社 pharmaceutical use of benzoic acid derivatives

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2218644C3 (en) * 1972-04-18 1982-08-19 Bayer Ag, 5090 Leverkusen Basic esters of 1,4-dihydropyridines, processes for their preparation and their use as pharmaceuticals
JPS5720953B2 (en) * 1974-04-18 1982-05-04
JPS575790B2 (en) * 1974-04-25 1982-02-01
DE2747513A1 (en) * 1977-10-22 1979-05-03 Bayer Ag DIHYDROPYRIDINE WITH SULFUR-CONTAINING ESTER GROUPS
DE2847236A1 (en) * 1978-10-31 1980-05-14 Bayer Ag NEW DIHYDROPYRIDINE WITH SUBSTITUTED ESTER GROUPS, MORE PROCEDURES FOR THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS
JPS56140989A (en) * 1980-04-03 1981-11-04 Yoshitomi Pharmaceut Ind Ltd 1,4-dihydrophyridine-3,5-dicarboxylic ester derivative or its salt
JPS57200386A (en) * 1981-06-04 1982-12-08 Yoshitomi Pharmaceut Ind Ltd Novel 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its salts
JPS58131982A (en) * 1982-02-01 1983-08-06 Tokyo Tanabe Co Ltd Novel 1,4-dihydropyridine derivative
US4656181A (en) * 1982-11-24 1987-04-07 Cermol S.A. Esters of 1,4-dihydropyridines, processes for the preparation of the new esters, and medicaments containing the same
JPS60215684A (en) * 1984-04-11 1985-10-29 Toyama Chem Co Ltd Novel 1,4-dihydropyridine derivative and its salt

Also Published As

Publication number Publication date
JPH0374666B2 (en) 1991-11-27
EP0190364A1 (en) 1986-08-13
ES8802512A1 (en) 1988-06-16
DK165686D0 (en) 1986-04-11
ES557371A0 (en) 1988-06-16
ES557372A0 (en) 1988-01-01
JPS6147477A (en) 1986-03-07
US4737506A (en) 1988-04-12
ES8801206A1 (en) 1988-01-01
NO861422L (en) 1986-04-11
HU195500B (en) 1988-05-30
AU577152B2 (en) 1988-09-15
ES8707185A1 (en) 1987-07-16
DK165686A (en) 1986-04-11
EP0190364A4 (en) 1987-02-12
ES546136A0 (en) 1987-07-16
KR860700252A (en) 1986-08-01
AU4721785A (en) 1986-03-07
WO1986001206A1 (en) 1986-02-27

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee