HUP9901633A2 - Centkromán l-enantiomer alkalmazása gyógyszerkészítmény előállítására, amely alkalmas mellrák kezelésére vagy megelőzésére - Google Patents
Centkromán l-enantiomer alkalmazása gyógyszerkészítmény előállítására, amely alkalmas mellrák kezelésére vagy megelőzéséreInfo
- Publication number
- HUP9901633A2 HUP9901633A2 HU9901633A HUP9901633A HUP9901633A2 HU P9901633 A2 HUP9901633 A2 HU P9901633A2 HU 9901633 A HU9901633 A HU 9901633A HU P9901633 A HUP9901633 A HU P9901633A HU P9901633 A2 HUP9901633 A2 HU P9901633A2
- Authority
- HU
- Hungary
- Prior art keywords
- treatment
- enantiomer
- breast cancer
- centchroman
- prophylaxis
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title abstract 3
- 206010006187 Breast cancer Diseases 0.000 title abstract 2
- 208000026310 Breast neoplasm Diseases 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- XZEUAXYWNKYKPL-URLMMPGGSA-N ormeloxifene Chemical compound C1([C@@H]2[C@H](C3=CC=C(C=C3OC2(C)C)OC)C=2C=CC(OCCN3CCCC3)=CC=2)=CC=CC=C1 XZEUAXYWNKYKPL-URLMMPGGSA-N 0.000 title 1
- 229960003327 ormeloxifene Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000011321 prophylaxis Methods 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920001187 thermosetting polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A 3,4-transz-2,2-dimetil-3-fenil-4-[4-(2-(pirrőlidin-1-l)--etőxi)-fenil]-7-metőxi-krőmán l-enantiőmerjének vagy gyógyszerészetilegelfőgadható sójának felhasználására valamely gyógyszerészetilegelfőgadható hőrdőzóanyaggal együtt, gyógyszerkészítmény előállítására,amely alkalmas mellrák kezelésében vagy megelőző kezelésben történőfelhasználásra. ŕ
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1000096P | 1996-01-11 | 1996-01-11 | |
DK77696 | 1996-07-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP9901633A2 true HUP9901633A2 (hu) | 1999-10-28 |
HUP9901633A3 HUP9901633A3 (en) | 2000-02-28 |
Family
ID=26064631
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9901633A HUP9901633A3 (en) | 1996-01-11 | 1997-01-09 | Use of the l-enantiomer of centchroman for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of breast cancer |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0873119A1 (hu) |
JP (1) | JP2001500101A (hu) |
KR (1) | KR19990077157A (hu) |
AU (1) | AU1367197A (hu) |
BR (1) | BR9706966A (hu) |
CA (1) | CA2241462A1 (hu) |
CZ (1) | CZ217198A3 (hu) |
HU (1) | HUP9901633A3 (hu) |
IL (1) | IL124881A0 (hu) |
NO (1) | NO983177L (hu) |
PL (1) | PL328135A1 (hu) |
WO (1) | WO1997025034A1 (hu) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU1143899A (en) * | 1997-11-10 | 1999-05-31 | Novo Nordisk A/S | Transdermal delivery of 3,4-diarylchromans |
US7005428B1 (en) | 1998-06-11 | 2006-02-28 | Endorecherche, Inc. | Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors |
AU2004200099B2 (en) * | 1998-06-11 | 2006-11-02 | Endorecherche, Inc. | Medical Uses of A Selective Estrogen Receptor Modulator in Combination with Sex Steroid Precursors |
AU2011253842B2 (en) * | 1998-06-11 | 2014-08-14 | Endorecherche Inc. | Medical Uses of a Selective Estrogen Receptor Modulator in Combination with Sex Steroid Precursors |
US6465445B1 (en) | 1998-06-11 | 2002-10-15 | Endorecherche, Inc. | Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors |
WO2006042409A1 (en) | 2004-10-20 | 2006-04-27 | Endorecherche, Inc. | Sex steroid precursors alone or in combination with a selective estrogen receptor modulator and/or with estrogens and/or a type 5 cgmp phosphodiesterase inhibitor for the prevention and treatment of vaginal dryness and sexual dysfunction in postmenopausal women |
US8268806B2 (en) | 2007-08-10 | 2012-09-18 | Endorecherche, Inc. | Pharmaceutical compositions |
CN102940619A (zh) | 2007-10-16 | 2013-02-27 | 利普生物药剂公司 | 用于治疗代谢综合征的珠氯米芬 |
US20100317635A1 (en) | 2009-06-16 | 2010-12-16 | Endorecherche, Inc. | Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators |
CA2802761C (en) | 2010-06-16 | 2017-01-03 | Endorecherche, Inc. | Methods of treating or preventing estrogen-related diseases |
CA2865234A1 (en) | 2012-02-29 | 2013-09-06 | Repros Therapeutics Inc. | Combination therapy for treating androgen deficiency |
US9744177B2 (en) | 2014-03-10 | 2017-08-29 | Endorecherche, Inc. | Treatment of male androgen deficiency symptoms or diseases with sex steroid precursor combined with SERM |
CN108348605B (zh) | 2015-11-10 | 2023-06-09 | 帕拉卡林治疗公司 | 用pdgf-cc抑制剂和抗***治疗er阴性乳癌 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4447622A (en) * | 1981-09-22 | 1984-05-08 | Council Of Scientific And Industrial Research Rafi Marg | Preparation of l- and d-isomers of dl-3,4-trans-2,2-disubstituted-3,4-diarylchromans and derivatives thereof |
-
1997
- 1997-01-09 BR BR9706966A patent/BR9706966A/pt not_active Application Discontinuation
- 1997-01-09 KR KR1019980705295A patent/KR19990077157A/ko not_active Application Discontinuation
- 1997-01-09 JP JP09524767A patent/JP2001500101A/ja active Pending
- 1997-01-09 WO PCT/DK1997/000007 patent/WO1997025034A1/en not_active Application Discontinuation
- 1997-01-09 IL IL12488197A patent/IL124881A0/xx unknown
- 1997-01-09 AU AU13671/97A patent/AU1367197A/en not_active Abandoned
- 1997-01-09 EP EP97900199A patent/EP0873119A1/en not_active Withdrawn
- 1997-01-09 PL PL97328135A patent/PL328135A1/xx unknown
- 1997-01-09 CA CA002241462A patent/CA2241462A1/en not_active Abandoned
- 1997-01-09 CZ CZ982171A patent/CZ217198A3/cs unknown
- 1997-01-09 HU HU9901633A patent/HUP9901633A3/hu unknown
-
1998
- 1998-07-10 NO NO983177A patent/NO983177L/no unknown
Also Published As
Publication number | Publication date |
---|---|
BR9706966A (pt) | 1999-05-04 |
PL328135A1 (en) | 1999-01-18 |
AU1367197A (en) | 1997-08-01 |
HUP9901633A3 (en) | 2000-02-28 |
CA2241462A1 (en) | 1997-07-17 |
EP0873119A1 (en) | 1998-10-28 |
KR19990077157A (ko) | 1999-10-25 |
IL124881A0 (en) | 1999-01-26 |
JP2001500101A (ja) | 2001-01-09 |
CZ217198A3 (cs) | 1998-11-11 |
WO1997025034A1 (en) | 1997-07-17 |
NO983177L (no) | 1998-07-10 |
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