HUP9702458A2 - Human interleukin-1 receptor accessory protein - Google Patents
Human interleukin-1 receptor accessory proteinInfo
- Publication number
- HUP9702458A2 HUP9702458A2 HU9702458A HUP9702458A HUP9702458A2 HU P9702458 A2 HUP9702458 A2 HU P9702458A2 HU 9702458 A HU9702458 A HU 9702458A HU P9702458 A HUP9702458 A HU P9702458A HU P9702458 A2 HUP9702458 A2 HU P9702458A2
- Authority
- HU
- Hungary
- Prior art keywords
- accessory protein
- receptor accessory
- human interleukin
- protein
- receptor
- Prior art date
Links
- 101000960952 Homo sapiens Interleukin-1 receptor accessory protein Proteins 0.000 title 1
- 102000046828 human IL1RAP Human genes 0.000 title 1
- 102100039880 Interleukin-1 receptor accessory protein Human genes 0.000 abstract 3
- 101710180389 Interleukin-1 receptor accessory protein Proteins 0.000 abstract 3
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 102000000589 Interleukin-1 Human genes 0.000 abstract 1
- 108010002352 Interleukin-1 Proteins 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
A találmány hűmán IL-1 receptőr járűlékős fehérjét kódőlópőlinűkleőtidőkra, izőlált IL-1 receptőr járűlékős fehérjére és IL-1receptőr járűlékős fehérje antitestjeire vőnatkőzik. A találmányszerinti fehérje IL-1 hatása által őkőzőtt gyűlladásőkmegakadályőzására különösen előnyösen alkalmazható. ŕThe invention faithfully describes IL-1 receptor accessory protein coding sequences, isolated IL-1 receptor accessory protein, and IL-1 receptor accessory protein antibodies. The protein according to the invention can be particularly advantageously used to prevent inflammation caused by the effect of IL-1. ŕ
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37626895A | 1995-01-23 | 1995-01-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUP9702458A2 true HUP9702458A2 (en) | 1998-04-28 |
Family
ID=23484321
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9702458A HUP9702458A2 (en) | 1995-01-23 | 1996-01-17 | Human interleukin-1 receptor accessory protein |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0808365A1 (en) |
| JP (1) | JPH10512453A (en) |
| AR (1) | AR003919A1 (en) |
| AU (1) | AU4537096A (en) |
| BR (1) | BR9606837A (en) |
| CA (1) | CA2210724A1 (en) |
| CO (1) | CO4480033A1 (en) |
| CZ (1) | CZ208197A3 (en) |
| EA (1) | EA199700265A1 (en) |
| FI (1) | FI973089A (en) |
| HU (1) | HUP9702458A2 (en) |
| IL (1) | IL116796A0 (en) |
| MX (1) | MX9705501A (en) |
| NO (1) | NO973404D0 (en) |
| PE (1) | PE64396A1 (en) |
| PL (1) | PL321538A1 (en) |
| TR (1) | TR199700652T1 (en) |
| WO (1) | WO1996023067A1 (en) |
| ZA (1) | ZA96333B (en) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6974682B1 (en) | 1996-08-26 | 2005-12-13 | Human Genome Sciences, Inc. | Soluble interleukin-1 receptor accessory molecule |
| AU7011696A (en) * | 1996-08-26 | 1998-03-19 | Human Genome Sciences, Inc. | Soluble interleukin-1 receptor accessory molecule |
| EP2002846B1 (en) | 1996-12-06 | 2017-01-25 | Amgen Inc. | Combination therapy using an IL-1 inhibitor for treating IL-1 mediated diseases |
| US6294170B1 (en) | 1997-08-08 | 2001-09-25 | Amgen Inc. | Composition and method for treating inflammatory diseases |
| AU741330B2 (en) * | 1997-04-30 | 2001-11-29 | F. Hoffmann-La Roche Ag | Rat ST38.2 chemokine |
| US6280955B1 (en) * | 1997-12-16 | 2001-08-28 | Tularik Inc. | Interleukin-1 receptor accessory proteins, nucleic acids and methods |
| WO1999032626A1 (en) | 1997-12-23 | 1999-07-01 | Immunex Corporation | Sigirr dna and polypeptides |
| US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
| AU2002253842A1 (en) | 2000-10-31 | 2002-08-28 | Immunex Corporation | Il-1 receptor accessory protein |
| GB2375604A (en) * | 2001-05-18 | 2002-11-20 | Warner Lambert Co | Methods for screening using interleukin soluble trimolecular complex |
| NZ530765A (en) | 2001-06-26 | 2006-11-30 | Amgen Fremont Inc | Antibodies that bind OPGL and compositions and methods for the treatment of bone diseases |
| KR100453877B1 (en) | 2001-07-26 | 2004-10-20 | 메덱스젠 주식회사 | METHOD OF MANUFACTURING Ig-FUSION PROTEINS BY CONCATAMERIZATION, TNFR/Fc FUSION PROTEINS MANUFACTURED BY THE METHOD, DNA CODING THE PROTEINS, VECTORS INCLUDING THE DNA, AND CELLS TRANSFORMED BY THE VECTOR |
| AU2002324625B2 (en) * | 2001-08-07 | 2008-05-08 | Immunex Corporation | Interleukin-1 receptors in the treatment of diseases |
| MXPA05002514A (en) | 2002-09-06 | 2005-05-27 | Amgen Inc | Therapeutic human anti-il-1r1 monoclonal antibody. |
| DK1729810T3 (en) | 2004-04-02 | 2018-12-03 | Swedish Orphan Biovitrum Ab Publ | PROCEDURE FOR REDUCING AGGREGATION OF IL-1RA |
| US8618054B2 (en) | 2004-05-05 | 2013-12-31 | Valorisation-Rechereche Société en Commandite | Interleukin-1 receptor antagonists, compositions, and methods of treatment |
| CA2607113C (en) * | 2004-05-05 | 2013-11-12 | Valorisation-Recherche, Societe En Commandite | Interleukin-1 receptor antagonists, compositions, and methods of treatment |
| JP2008542685A (en) * | 2005-05-05 | 2008-11-27 | ヴァロリザーシヨン・アッシュエスジ，ソシエテ・アン・コマンディット | Cytokine receptor modifier and use thereof |
| PE20070684A1 (en) | 2005-11-14 | 2007-08-06 | Amgen Inc | RANKL-PTH / PTHrP ANTIBODY CHEMERICAL MOLECULES |
| US20110044894A1 (en) | 2008-03-26 | 2011-02-24 | Cellerant Therapeutics, Inc. | Immunoglobulin and/or Toll-Like Receptor Proteins Associated with Myelogenous Haematological Proliferative Disorders and Uses Thereof |
| EP2196476A1 (en) | 2008-12-10 | 2010-06-16 | Novartis Ag | Antibody formulation |
| GB2472856B (en) * | 2009-08-21 | 2012-07-11 | Cantargia Ab | IL1-RAP modulators and uses thereof |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| DK3020730T3 (en) | 2011-01-19 | 2019-04-15 | Cantargia Ab | ANTI-IL1RAP ANTIBODIES AND THEIR USE FOR TREATMENT OF SOLID TUMORS |
| AU2011358564B9 (en) | 2011-02-09 | 2017-07-13 | Natera, Inc | Methods for non-invasive prenatal ploidy calling |
| US20150030586A1 (en) * | 2011-06-21 | 2015-01-29 | Sarah Ellen Warren | Compositions and methods for the therapy and diagnosis of cancer |
| US8841418B2 (en) | 2011-07-01 | 2014-09-23 | Cellerant Therapeutics, Inc. | Antibodies that specifically bind to TIM3 |
| GB201403875D0 (en) | 2014-03-05 | 2014-04-16 | Cantargia Ab | Novel antibodies and uses thereof |
| GB201413913D0 (en) | 2014-08-06 | 2014-09-17 | Cantargia Ab | Novel antibodies and uses thereof |
| US11479812B2 (en) | 2015-05-11 | 2022-10-25 | Natera, Inc. | Methods and compositions for determining ploidy |
| CA2990305A1 (en) | 2015-06-26 | 2016-12-29 | Mab Discovery Gmbh | Monoclonal anti-il-1racp antibodies |
| EP3241845A1 (en) | 2016-05-06 | 2017-11-08 | MAB Discovery GmbH | Humanized anti-il-1r3 antibodies |
| US10041044B2 (en) | 2016-07-29 | 2018-08-07 | Trustees Of Boston University | Age-associated clonal hematopoiesis accelerates cardio-metabolic disease development |
| EP3401332A1 (en) | 2017-05-08 | 2018-11-14 | MAB Discovery GmbH | Anti-il-1r3 antibodies for use in inflammatory conditions |
| CN110945136A (en) | 2017-06-20 | 2020-03-31 | 威斯康星州立大学医学院 | Assessment of risk of transplantation complications using total cell-free DNA |
| TW202021618A (en) | 2018-08-17 | 2020-06-16 | 美商２３與我有限公司 | Anti-il1rap antibodies and methods of use thereof |
| US11931674B2 (en) | 2019-04-04 | 2024-03-19 | Natera, Inc. | Materials and methods for processing blood samples |
| WO2021236962A1 (en) | 2020-05-20 | 2021-11-25 | The Medical College Of Wisconsin, Inc. | Compositions and methods for inhibiting cytokine-release syndrome |
| WO2022247937A1 (en) * | 2021-05-28 | 2022-12-01 | Biocytogen Jiangsu Co., Ltd. | Genetically modified non-human animal with human or chimeric il1rap |
-
1996
- 1996-01-15 PE PE1996000031A patent/PE64396A1/en not_active Application Discontinuation
- 1996-01-16 ZA ZA96333A patent/ZA96333B/en unknown
- 1996-01-17 EP EP96901291A patent/EP0808365A1/en not_active Withdrawn
- 1996-01-17 EA EA199700265A patent/EA199700265A1/en unknown
- 1996-01-17 HU HU9702458A patent/HUP9702458A2/en unknown
- 1996-01-17 CZ CZ972081A patent/CZ208197A3/en unknown
- 1996-01-17 IL IL11679696A patent/IL116796A0/en unknown
- 1996-01-17 CA CA002210724A patent/CA2210724A1/en not_active Abandoned
- 1996-01-17 AU AU45370/96A patent/AU4537096A/en not_active Abandoned
- 1996-01-17 WO PCT/EP1996/000181 patent/WO1996023067A1/en not_active Application Discontinuation
- 1996-01-17 PL PL96321538A patent/PL321538A1/en unknown
- 1996-01-17 BR BR9606837A patent/BR9606837A/en unknown
- 1996-01-17 MX MX9705501A patent/MX9705501A/en unknown
- 1996-01-17 JP JP8522598A patent/JPH10512453A/en active Pending
- 1996-01-17 TR TR97/00652T patent/TR199700652T1/en unknown
- 1996-01-19 AR ARP960101095A patent/AR003919A1/en unknown
- 1996-01-22 CO CO96002329A patent/CO4480033A1/en unknown
-
1997
- 1997-07-22 FI FI973089A patent/FI973089A/en unknown
- 1997-07-23 NO NO973404A patent/NO973404D0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR9606837A (en) | 1998-05-26 |
| NO973404L (en) | 1997-07-23 |
| IL116796A0 (en) | 1996-05-14 |
| FI973089A0 (en) | 1997-07-22 |
| MX9705501A (en) | 1997-10-31 |
| EP0808365A1 (en) | 1997-11-26 |
| JPH10512453A (en) | 1998-12-02 |
| EA199700265A1 (en) | 1998-04-30 |
| FI973089A (en) | 1997-07-22 |
| CZ208197A3 (en) | 1997-11-12 |
| PL321538A1 (en) | 1997-12-08 |
| AR003919A1 (en) | 1998-09-30 |
| ZA96333B (en) | 1996-07-23 |
| NO973404D0 (en) | 1997-07-23 |
| TR199700652T1 (en) | 1998-02-21 |
| WO1996023067A1 (en) | 1996-08-01 |
| CA2210724A1 (en) | 1996-08-01 |
| PE64396A1 (en) | 1997-01-28 |
| AU4537096A (en) | 1996-08-14 |
| CO4480033A1 (en) | 1997-07-09 |
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