HUP0402586A2 - Azetidinszármazékot tartalmazó gyógyszerészeti készítmények - Google Patents

Azetidinszármazékot tartalmazó gyógyszerészeti készítmények

Info

Publication number
HUP0402586A2
HUP0402586A2 HU0402586A HUP0402586A HUP0402586A2 HU P0402586 A2 HUP0402586 A2 HU P0402586A2 HU 0402586 A HU0402586 A HU 0402586A HU P0402586 A HUP0402586 A HU P0402586A HU P0402586 A2 HUP0402586 A2 HU P0402586A2
Authority
HU
Hungary
Prior art keywords
composition
azetidine
general formula
azetidine derivative
active ingredient
Prior art date
Application number
HU0402586A
Other languages
English (en)
Inventor
Sophie Coté
Valérie Bobineau
Maria-Teresa Peracchia
Original Assignee
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.
Publication of HUP0402586A2 publication Critical patent/HUP0402586A2/hu
Publication of HUP0402586A3 publication Critical patent/HUP0402586A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

A találmány tárgya stabil gyógyszerészeti készítmény, amely legalábbegy (Ia) vagy (Ib) általános képletű azetidinszármazékot tartalmaz,ahol Ar jelentése aromás vagy heteroaromás csoport, amely adottesetben szubsztituálva van egy vagy több 1-4 szénatomosalkilcsoporttal, halogénatommal, nitro-, ciano-, 1-4 szénatomosalkoxi- vagy hidroxilcsoporttal, adott esetben egy másik az (Ia) vagy(Ib) általános képletű azetidinszármazék hatását erősíteni képeshatóanyaggal együtt egy olyan rendszerben, amely legfeljebb két fővivőanyagot tartalmaz, amelyet a következők közül választanak: egyhidrofil jellegű nercionos felületaktív anyag, amely képes az (Ia)vagy (Ib) általános képletű azetidinszármazék és adott esetben azazetidinszármazék hatását erősítő hatóanyag oldhatóvá tételére éskolloid rendszer kialakulásának kiváltására, és adott esetben egymásodik lipofil jellegű, az összetételt stabilizáló vivőanyag. Az (Ia)vagy (Ib) általános képletű azetidinszármazékokat tartalmazógyógyszerkészítmények a kannabinoid receptorokkal szemben mutatnakaffinitást. A találmány a készítmény előállítására szolgáló eljárástés a készítményt és egy második hatóanyagot tartalmazó készítményttartalmazó készletet is magába foglal. Ó
HU0402586A 2001-12-21 2002-12-20 Pharmaceutical compositions based on azetidine derivatives HUP0402586A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0116638A FR2833842B1 (fr) 2001-12-21 2001-12-21 Compositions pharmaceutiques a base de derives d'azetidine
PCT/FR2002/004514 WO2003053431A2 (fr) 2001-12-21 2002-12-20 Compositions pharmaceutiques a base de derives d'azetidine

Publications (2)

Publication Number Publication Date
HUP0402586A2 true HUP0402586A2 (hu) 2005-03-29
HUP0402586A3 HUP0402586A3 (en) 2011-05-30

Family

ID=8870824

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0402586A HUP0402586A3 (en) 2001-12-21 2002-12-20 Pharmaceutical compositions based on azetidine derivatives

Country Status (32)

Country Link
EP (1) EP1458413B1 (hu)
JP (1) JP5021887B2 (hu)
KR (1) KR20040068308A (hu)
CN (1) CN100388918C (hu)
AP (1) AP1754A (hu)
AR (1) AR037687A1 (hu)
AU (1) AU2002364866B2 (hu)
BR (1) BR0215048A (hu)
CA (1) CA2470443A1 (hu)
CO (1) CO5590911A2 (hu)
DE (1) DE60233071D1 (hu)
DK (1) DK1458413T3 (hu)
EA (1) EA006510B1 (hu)
EC (1) ECSP045162A (hu)
FR (1) FR2833842B1 (hu)
HK (1) HK1070840A1 (hu)
HR (1) HRP20040575A2 (hu)
HU (1) HUP0402586A3 (hu)
IL (1) IL162563A0 (hu)
MA (1) MA27086A1 (hu)
ME (1) MEP16608A (hu)
MX (1) MXPA04005558A (hu)
MY (1) MY138172A (hu)
NO (1) NO20042781L (hu)
NZ (1) NZ533225A (hu)
OA (1) OA12750A (hu)
PL (1) PL203248B1 (hu)
RS (1) RS55504A (hu)
TW (1) TWI256304B (hu)
UA (1) UA77736C2 (hu)
WO (1) WO2003053431A2 (hu)
ZA (1) ZA200404338B (hu)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1498122A1 (en) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Semi-solid systems containing azetidine derivatives
EP1498123A1 (en) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Emulsifying systems containing azetidine derivatives
WO2005077897A1 (en) 2004-02-17 2005-08-25 Laboratorios Del Dr. Esteve S.A. Substituted azetidine compounds, their preparation and use as medicaments
FR2879932B1 (fr) * 2004-12-27 2007-03-23 Aventis Pharma Sa Formulations injectable ou administrable par voie orale de derives d'azetidine
AU2006264649A1 (en) 2005-06-30 2007-01-11 Prosidion Limited GPCR agonists
GB0700122D0 (en) 2007-01-04 2007-02-14 Prosidion Ltd GPCR agonists
AR064736A1 (es) 2007-01-04 2009-04-22 Prosidion Ltd Agonistas de gpcr
WO2008081204A1 (en) 2007-01-04 2008-07-10 Prosidion Limited Piperidine gpcr agonists
WO2008081208A1 (en) 2007-01-04 2008-07-10 Prosidion Limited Piperidine gpcr agonists
CL2008000018A1 (es) 2007-01-04 2008-08-01 Prosidion Ltd Compuestos derivados de heterociclos de nitrogeno y oxigeno, agonistas de gpcr; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la obesidad, diabetes, sindrome metabolico, hiperlipidemia, toleranci
GB0720390D0 (en) 2007-10-18 2007-11-28 Prosidion Ltd G-Protein coupled receptor agonists
GB0720389D0 (en) 2007-10-18 2008-11-12 Prosidion Ltd G-Protein Coupled Receptor Agonists
FR2923719B1 (fr) * 2007-11-15 2009-11-20 Sanofi Aventis Compositions pharmaceutiques a base de derives d'azetidine
FR2928149B1 (fr) 2008-02-29 2011-01-14 Sanofi Aventis Composes derives d'azetidines, leur preparation et leur application en therapeutique
FR2946650B1 (fr) * 2009-06-16 2011-08-19 Sanofi Aventis Esters derives d'azetidines, leur preparation et leur application en therapeutique.
UA153183U (uk) 2022-10-27 2023-05-31 Андрій Валерійович Максимов Стаканчик для приготування напою

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR73668B (hu) * 1978-11-21 1984-03-28 Hoffmann La Roche
US5631365A (en) * 1993-09-21 1997-05-20 Schering Corporation Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
HRP980026A2 (en) * 1998-01-20 1999-10-31 Pliva Pharm & Chem Works 1-izothiazolydinone derivatives of azetidine-2-ones, processes for the preparation and use thereof
WO2000003753A2 (en) * 1998-07-14 2000-01-27 Em Industries, Inc. Microdisperse drug delivery systems
FR2783246B1 (fr) * 1998-09-11 2000-11-17 Aventis Pharma Sa Derives d'azetidine, leur preparation et les medicaments les contenant
FR2805818B1 (fr) * 2000-03-03 2002-04-26 Aventis Pharma Sa Derives d'azetidine, leur preparation et les compositions pharmaceutiques les contenant
FR2805810B1 (fr) * 2000-03-03 2002-04-26 Aventis Pharma Sa Compositions pharmaceutiques contenant des derives de 3- amino-azetidine, les nouveaux derives et leur preparation
FR2805817B1 (fr) * 2000-03-03 2002-04-26 Aventis Pharma Sa Compositions pharmaceutiques contenant des derives d'azetidine, les nouveaux derives d'azetidine et leur preparation
FR2814678B1 (fr) * 2000-10-04 2002-12-20 Aventis Pharma Sa Association d'un antagoniste du recepteur cb1 et de sibutramine, les compositions pharmaceutiques les contenant et leur utilisation pour la traitement de l'obesite

Also Published As

Publication number Publication date
DE60233071D1 (de) 2009-09-03
EP1458413B1 (fr) 2009-07-22
AR037687A1 (es) 2004-12-01
UA77736C2 (en) 2007-01-15
KR20040068308A (ko) 2004-07-30
NZ533225A (en) 2007-02-23
WO2003053431A2 (fr) 2003-07-03
NO20042781L (no) 2004-09-20
HK1070840A1 (en) 2005-06-30
CN1602206A (zh) 2005-03-30
MA27086A1 (fr) 2004-12-20
TW200301108A (en) 2003-07-01
CA2470443A1 (fr) 2003-07-03
AP2004003066A0 (en) 2004-06-30
MY138172A (en) 2009-04-30
FR2833842A1 (fr) 2003-06-27
AP1754A (en) 2007-07-18
CN100388918C (zh) 2008-05-21
ECSP045162A (es) 2004-08-27
MXPA04005558A (es) 2004-12-06
EP1458413A2 (fr) 2004-09-22
PL372708A1 (en) 2005-07-25
EA200400843A1 (ru) 2004-12-30
CO5590911A2 (es) 2005-12-30
ZA200404338B (en) 2005-06-02
FR2833842B1 (fr) 2004-02-13
IL162563A0 (en) 2005-11-20
MEP16608A (en) 2010-06-10
RS55504A (en) 2007-06-04
JP5021887B2 (ja) 2012-09-12
OA12750A (fr) 2006-07-03
DK1458413T3 (da) 2009-11-23
AU2002364866B2 (en) 2006-11-30
EA006510B1 (ru) 2005-12-29
HUP0402586A3 (en) 2011-05-30
TWI256304B (en) 2006-06-11
HRP20040575A2 (en) 2004-10-31
WO2003053431A3 (fr) 2003-12-18
PL203248B1 (pl) 2009-09-30
AU2002364866A1 (en) 2003-07-09
BR0215048A (pt) 2004-11-03
JP2005516945A (ja) 2005-06-09

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees