HUP0303838A3 - Erythropoietin ameliorates chemotherapy-induced toxicity in vivo - Google Patents

Erythropoietin ameliorates chemotherapy-induced toxicity in vivo

Info

Publication number: HUP0303838A3
Authority: HU; Hungary
Prior art keywords: ameliorates; erythropoietin; chemotherapy; vivo; induced toxicity
Prior art date: 2001-04-09

Application number

HU0303838A

Other languages

English (en)

Original Assignee

Univ East Carolina

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-04-09

Filing date

2002-04-08

Publication date

2010-03-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23082337&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0303838(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-04-08 Application filed by Univ East Carolina filed Critical Univ East Carolina

2004-03-01 Publication of HUP0303838A2 publication Critical patent/HUP0303838A2/hu

2010-03-29 Publication of HUP0303838A3 publication Critical patent/HUP0303838A3/hu

Links

102000003951 Erythropoietin Human genes 0.000 title 1
108090000394 Erythropoietin Proteins 0.000 title 1
238000002512 chemotherapy Methods 0.000 title 1
229940105423 erythropoietin Drugs 0.000 title 1
238000001727 in vivo Methods 0.000 title 1
OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 title 1
230000001988 toxicity Effects 0.000 title 1
231100000419 toxicity Toxicity 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Zoology (AREA)
Toxicology (AREA)
Neurology (AREA)
Pulmonology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)

HU0303838A 2001-04-09 2002-04-08 Erythropoietin ameliorates chemotherapy-induced toxicity in vivo HUP0303838A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US28262101P	2001-04-09	2001-04-09
PCT/US2002/011081 WO2002080676A1 (en)	2001-04-09	2002-04-08	Erythropoietin ameliorates chemotherapy-induced toxicity in vivo

Publications (2)

Publication Number	Publication Date
HUP0303838A2 HUP0303838A2 (hu)	2004-03-01
HUP0303838A3 true HUP0303838A3 (en)	2010-03-29

Family

ID=23082337

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU0303838A HUP0303838A3 (en)	2001-04-09	2002-04-08	Erythropoietin ameliorates chemotherapy-induced toxicity in vivo

Country Status (22)

Country	Link
US (2)	US20020169128A1 (hu)
EP (1)	EP1377164B1 (hu)
JP (1)	JP4428924B2 (hu)
KR (1)	KR100885525B1 (hu)
CN (2)	CN101152565A (hu)
AT (1)	ATE399020T1 (hu)
AU (1)	AU2002256133B2 (hu)
BR (1)	BR0208727A (hu)
CA (1)	CA2443025A1 (hu)
DE (1)	DE60227244D1 (hu)
DK (1)	DK1377164T3 (hu)
ES (1)	ES2309166T3 (hu)
HU (1)	HUP0303838A3 (hu)
IL (3)	IL158155A0 (hu)
MX (1)	MXPA03009182A (hu)
NO (1)	NO20034504L (hu)
NZ (1)	NZ528675A (hu)
PL (1)	PL373361A1 (hu)
PT (1)	PT1377164E (hu)
RU (1)	RU2296563C2 (hu)
WO (1)	WO2002080676A1 (hu)
ZA (1)	ZA200307803B (hu)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2686899B1 (fr) *	1992-01-31	1995-09-01	Rhone Poulenc Rorer Sa	Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
EP1997829A1 (en)	2001-12-21	2008-12-03	Human Genome Sciences, Inc.	Albumin fusion proteins
JP2007530440A (ja) *	2003-05-12	2007-11-01	アフィーマックス・インコーポレイテッド	新規ポリ（エチレングリコール）修飾化合物およびその用途
SG160224A1 (en) *	2003-05-12	2010-04-29	Affymax Inc	Novel peptides that bind to the erythropoietin receptor
PL1625156T3 (pl) *	2003-05-12	2013-03-29	Affymax Inc	Peptydy wiążące się do receptora erytropoetyny
EA010015B1 (ru) *	2003-05-12	2008-06-30	Афимакс, Инк.	Новый разделительный фрагмент (спейсер) для модифицированных полиэтиленгликолем соединений на основе пептидов
US20080312201A1 (en) *	2004-09-10	2008-12-18	Patrick Fogarty	Reduced Toxicity Methotrexate Formulations and Methods for Using the Same
WO2006062685A2 (en) *	2004-11-11	2006-06-15	Affymax, Inc.	Novel peptides that bind to the erythropoietin receptor
MX2007005777A (es) *	2004-11-11	2007-07-20	Affymax Inc	Peptidos novedosos que se unen al receptor de eritropoietina.
US8324159B2 (en) *	2005-06-03	2012-12-04	Affymax, Inc.	Erythropoietin receptor peptide formulations and uses
US7919461B2 (en)	2005-06-03	2011-04-05	Affymax, Inc.	Erythropoietin receptor peptide formulations and uses
US7550433B2 (en) *	2005-06-03	2009-06-23	Affymax, Inc.	Erythropoietin receptor peptide formulations and uses
WO2008023725A1 (fr) *	2006-08-22	2008-02-28	Chugai Seiyaku Kabushiki Kaisha	Agent préventif et/ou thérapeutique pour une neuropathie périphérique
US20080249001A1 (en) *	2006-10-25	2008-10-09	Ajinomoto Co. Inc.	Agents that alleviate side-effects caused by chemotherapy agents
EP1992355A1 (en) *	2007-05-16	2008-11-19	Eberhardt Spanuth	Pharmaceutical combination medication comprising NSAIDs or cytoxic drugs
US10668109B2 (en) *	2015-06-18	2020-06-02	Yeda Research And Development Co. Ltd.	Conditioning protocols and use of same for tissue regeneration
US10695402B2 (en)	2017-03-16	2020-06-30	University Of Rochester	Erythropoietin for gastrointestinal dysfunction
WO2022159414A1 (en)	2021-01-22	2022-07-28	University Of Rochester	Erythropoietin for gastroinfestinal dysfunction

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4859765A (en) *	1983-10-17	1989-08-22	Syntex (U.S.A.) Inc.	Synthetic peptide sequences useful in biological and pharmaceutical applications and methods of manufacture
US4863857A (en) *	1985-03-01	1989-09-05	Board Of Regents, The University Of Texas System	Polypeptide complementary to peptides or proteins having an amino acid sequence or nucleotide coding sequence at least partially known
NZ215865A (en) *	1985-04-22	1988-10-28	Commw Serum Lab Commission	Method of determining the active site of a receptor-binding analogue
IT210425Z2 (it) *	1987-01-22	1988-12-30	Erga Srl	Portachiavi con mezzo di scrittura telescopico incorporato
US4853871A (en) *	1987-04-06	1989-08-01	Genex Corporation	Computer-based method for designing stablized proteins
US4856871A (en) *	1987-08-31	1989-08-15	General Electric Company	Replaceable laser and lens assembly
JP2632014B2 (ja) *	1988-03-03	1997-07-16	中外製薬株式会社	骨髄機能障害性貧血治療剤
US20020052309A1 (en) *	1996-09-11	2002-05-02	Athanasius A. Anagnostou	Method of treating endothelial injury
US6719977B1 (en) *	1998-02-12	2004-04-13	The General Hospital Corporation	Methods to potentiate cancer therapies
PL360581A1 (en) *	1999-05-11	2004-09-06	Ortho-Mcneil Pharmaceutical, Inc.	Pharmacokinetic and pharmacodynamic modeling of erythropoietin administration
US6531121B2 (en) *	2000-12-29	2003-03-11	The Kenneth S. Warren Institute, Inc.	Protection and enhancement of erythropoietin-responsive cells, tissues and organs

2002
- 2002-04-05 US US10/117,011 patent/US20020169128A1/en not_active Abandoned
- 2002-04-08 CN CNA2007101533855A patent/CN101152565A/zh active Pending
- 2002-04-08 IL IL15815502A patent/IL158155A0/xx unknown
- 2002-04-08 JP JP2002578724A patent/JP4428924B2/ja not_active Expired - Fee Related
- 2002-04-08 DK DK02725577T patent/DK1377164T3/da active
- 2002-04-08 CN CNB028078136A patent/CN100379446C/zh not_active Expired - Fee Related
- 2002-04-08 CA CA002443025A patent/CA2443025A1/en not_active Abandoned
- 2002-04-08 HU HU0303838A patent/HUP0303838A3/hu unknown
- 2002-04-08 EP EP02725577A patent/EP1377164B1/en not_active Revoked
- 2002-04-08 PT PT02725577T patent/PT1377164E/pt unknown
- 2002-04-08 KR KR1020037013132A patent/KR100885525B1/ko not_active IP Right Cessation
- 2002-04-08 ES ES02725577T patent/ES2309166T3/es not_active Expired - Lifetime
- 2002-04-08 PL PL02373361A patent/PL373361A1/xx not_active Application Discontinuation
- 2002-04-08 BR BR0208727-8A patent/BR0208727A/pt not_active IP Right Cessation
- 2002-04-08 MX MXPA03009182A patent/MXPA03009182A/es active IP Right Grant
- 2002-04-08 AT AT02725577T patent/ATE399020T1/de not_active IP Right Cessation
- 2002-04-08 NZ NZ528675A patent/NZ528675A/en unknown
- 2002-04-08 DE DE60227244T patent/DE60227244D1/de not_active Expired - Lifetime
- 2002-04-08 RU RU2003132584/14A patent/RU2296563C2/ru not_active IP Right Cessation
- 2002-04-08 AU AU2002256133A patent/AU2002256133B2/en not_active Ceased
- 2002-04-08 WO PCT/US2002/011081 patent/WO2002080676A1/en active Application Filing
2003
- 2003-09-29 IL IL158155A patent/IL158155A/en not_active IP Right Cessation
- 2003-10-06 ZA ZA200307803A patent/ZA200307803B/en unknown
- 2003-10-08 NO NO20034504A patent/NO20034504L/no not_active Application Discontinuation
2009
- 2009-05-17 IL IL198783A patent/IL198783A0/en unknown
2011
- 2011-03-31 US US13/077,335 patent/US20110195046A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CN1499927A (zh)	2004-05-26
DE60227244D1 (de)	2008-08-07
IL158155A0 (en)	2004-03-28
KR20030087064A (ko)	2003-11-12
KR100885525B1 (ko)	2009-02-26
CN100379446C (zh)	2008-04-09
EP1377164A4 (en)	2005-05-04
CN101152565A (zh)	2008-04-02
ATE399020T1 (de)	2008-07-15
NO20034504D0 (no)	2003-10-08
PT1377164E (pt)	2008-09-30
RU2003132584A (ru)	2005-04-10
HUP0303838A2 (hu)	2004-03-01
CA2443025A1 (en)	2002-10-17
EP1377164B1 (en)	2008-06-25
MXPA03009182A (es)	2004-02-17
BR0208727A (pt)	2005-05-10
NZ528675A (en)	2006-10-27
NO20034504L (no)	2003-12-09
ES2309166T3 (es)	2008-12-16
EP1377164A1 (en)	2004-01-07
DK1377164T3 (da)	2008-10-13
PL373361A1 (en)	2005-08-22
US20110195046A1 (en)	2011-08-11
JP2004532840A (ja)	2004-10-28
IL158155A (en)	2009-12-24
WO2002080676A1 (en)	2002-10-17
ZA200307803B (en)	2005-02-09
AU2002256133B2 (en)	2007-05-31
US20020169128A1 (en)	2002-11-14
RU2296563C2 (ru)	2007-04-10
JP4428924B2 (ja)	2010-03-10
IL198783A0 (en)	2010-02-17

Legal Events

Date	Code	Title	Description
2012-01-30	FD9A	Lapse of provisional protection due to non-payment of fees

Publication	Publication Date	Title
HUP0401124A3 (en)	2006-01-30	Coagulation factor vii derivatives
EP1370249A4 (en)	2006-05-03	NEW DENDRITIC POLYMERS AND ITS BIOMEDICAL APPLICATIONS
HUP0303838A3 (en)	2010-03-29	Erythropoietin ameliorates chemotherapy-induced toxicity in vivo
IL159859A0 (en)	2004-06-20	Antineoplastic combinations
PL366510A1 (en)	2005-02-07	Pharmaceutical combinations
ZA200603888B (en)	2007-05-30	Antineoplastic combinations
HUP0400006A2 (hu)	2004-04-28	Antineopláziás kombinációs készítmények
IL161472A0 (en)	2004-09-27	In vitro micro-organs, and uses related thereto
EG23706A (en)	2007-05-27	4-Deoxy-4-(S)-amino avernectin derivatives
IL160960A0 (en)	2004-08-31	Reduced toxicity cisplatin formulations and methods for using the same
EP1450921A4 (en)	2005-02-23	IMPROVEMENTS RELATING TO EVAPORATORS
GB2388047B (en)	2005-06-01	Game
GB0118126D0 (en)	2001-09-19	Improvements in or relating to vapourisers
GB0130856D0 (en)	2002-02-06	Game
TW488401U (en)	2002-05-21	The differential for use in low power
GB0123487D0 (en)	2001-11-21	Two in one
AU146841S (en)	2002-02-11	Peg
AU146840S (en)	2002-02-11	Peg
CA91434S (en)	2001-01-31	Stand
GB0122569D0 (en)	2001-11-07	Game:- Stranger danger
GB0112388D0 (en)	2001-07-11	One in five
GB0118538D0 (en)	2001-09-19	Game show
GB0113959D0 (en)	2001-08-01	Game
GB0108562D0 (en)	2001-05-23	Game
GB0107169D0 (en)	2001-05-09	Game