HUP0202340A2 - Hatóanyagként kondenzált heterociklusos vegyületeket tartalmazó gyógyszerkészítmények és alkalmazásuk - Google Patents

Hatóanyagként kondenzált heterociklusos vegyületeket tartalmazó gyógyszerkészítmények és alkalmazásuk

Info

Publication number
HUP0202340A2
HUP0202340A2 HU0202340A HUP0202340A HUP0202340A2 HU P0202340 A2 HUP0202340 A2 HU P0202340A2 HU 0202340 A HU0202340 A HU 0202340A HU P0202340 A HUP0202340 A HU P0202340A HU P0202340 A2 HUP0202340 A2 HU P0202340A2
Authority
HU
Hungary
Prior art keywords
heterocyclic compounds
condensed heterocyclic
ylmethyl
optionally substituted
active ingredient
Prior art date
Application number
HU0202340A
Other languages
English (en)
Inventor
Takashi Fujita
Kosaku Fujiwara
Shinichi Kurakata
Original Assignee
Sankyo Company, Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Company, Limited filed Critical Sankyo Company, Limited
Publication of HUP0202340A2 publication Critical patent/HUP0202340A2/hu
Publication of HUP0202340A3 publication Critical patent/HUP0202340A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms

Abstract

Az (I) általános képletű kondenzált heterociklusos vegyületek ésgyógyászatilag elfogadható sóik, melyek a rák gyógyítására ésmegelőzésére alkalmasak. Az (I) általános képletben X jelentésebenzimidazolilcsoport, mely adott esetben 1-5 szubsztituensselhelyettesített; Y jelentése oxigén- vagy kénatom, Z jelentése (i) 2,4-dioxo-tiazolidin-5-ilidénil-metilcsoport; (ii) 2,4-dioxo-tiazolidin-5-il-metilcsoport; (iii) 2,4-dioxo-oxazolidin-5-il-metilcsoport; (iv)3,5-dioxo-oxadiazolidin-2-il-metilcsoport; illetve (v) N-hidroxi-ureido-metilcsoport]; R jelentése hidrogén-, halogénatom, alkil-,alkoxi-, hidroxil-, nitro-, adott esetben szubsztituált aminocsoportvagy adott esetben szubsztituált aralkilcsoport; m jelentése 1-5-igbezárólag egész szám. A találmány kiterjed a vegyületeket tartalmazógyógyszerkészítményekre is. Ó
HU0202340A 1999-07-19 2000-07-19 Pharmaceutical compositions containing condensed heterocyclic compounds as active ingredient and their use HUP0202340A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP20447699 1999-07-19
PCT/JP2000/004858 WO2001005402A1 (fr) 1999-07-19 2000-07-19 Agents preventifs et therapeutiques du cancer

Publications (2)

Publication Number Publication Date
HUP0202340A2 true HUP0202340A2 (hu) 2003-02-28
HUP0202340A3 HUP0202340A3 (en) 2006-03-28

Family

ID=16491170

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0202340A HUP0202340A3 (en) 1999-07-19 2000-07-19 Pharmaceutical compositions containing condensed heterocyclic compounds as active ingredient and their use

Country Status (18)

Country Link
US (1) US6569877B2 (hu)
EP (1) EP1197211A4 (hu)
KR (1) KR20020015383A (hu)
CN (1) CN1374864A (hu)
AU (1) AU760917B2 (hu)
BR (1) BR0012591A (hu)
CA (1) CA2379662A1 (hu)
CZ (1) CZ2002178A3 (hu)
HU (1) HUP0202340A3 (hu)
IL (1) IL147593A0 (hu)
MX (1) MXPA02000757A (hu)
NO (1) NO20020291L (hu)
NZ (1) NZ516636A (hu)
PL (1) PL352681A1 (hu)
RU (1) RU2219928C2 (hu)
TR (1) TR200200111T2 (hu)
WO (1) WO2001005402A1 (hu)
ZA (1) ZA200200316B (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI284533B (en) * 1999-05-24 2007-08-01 Sankyo Co Pharmaceutical composition for treating hyperglycemia, impaired glucose tolerance, diabetes complications and for improving insulin resistant
US9092523B2 (en) 2005-02-28 2015-07-28 Search Engine Technologies, Llc Methods of and systems for searching by incorporating user-entered information
WO2006102122A2 (en) 2005-03-18 2006-09-28 Wink Technologies, Inc. Search engine that applies feedback from users to improve search results
TW200745099A (en) * 2006-03-02 2007-12-16 Sankyo Co Optically active thiazolidinedione derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3152992B2 (ja) * 1992-04-03 2001-04-03 株式会社興人 過酸化脂質の生成抑制及び消去用組成物
US5734067A (en) 1994-09-28 1998-03-31 Nippon Suisan Kaisha, Ltd. Anti-oxidative tricyclic, condensed heterocyclic compound
JP3820601B2 (ja) * 1995-03-27 2006-09-13 大塚製薬株式会社 活性酸素消去剤
IL118474A (en) * 1995-06-01 2001-08-08 Sankyo Co Benzimideol derivatives and pharmaceutical preparations containing them
US5814647A (en) * 1997-03-04 1998-09-29 Board Of Regents, The University Of Texas System Use of troglitazone and related compounds for the treatment of the climacteric symptoms
AU740704B2 (en) 1997-10-08 2001-11-15 Sankyo Company Limited Substituted fused heterocyclic compounds
WO1999030739A1 (fr) * 1997-12-16 1999-06-24 Sankyo Company, Limited Remede contre la leucemie
US6878896B2 (en) * 2002-07-24 2005-04-12 United Parcel Service Of America, Inc. Synchronous semi-automatic parallel sorting

Also Published As

Publication number Publication date
BR0012591A (pt) 2002-04-09
HUP0202340A3 (en) 2006-03-28
US6569877B2 (en) 2003-05-27
NZ516636A (en) 2004-01-30
PL352681A1 (en) 2003-09-08
KR20020015383A (ko) 2002-02-27
AU6021200A (en) 2001-02-05
EP1197211A1 (en) 2002-04-17
CZ2002178A3 (cs) 2002-05-15
AU760917B2 (en) 2003-05-22
RU2219928C2 (ru) 2003-12-27
MXPA02000757A (es) 2002-07-22
US20020137776A1 (en) 2002-09-26
TR200200111T2 (tr) 2002-08-21
ZA200200316B (en) 2003-06-25
CA2379662A1 (en) 2001-01-25
IL147593A0 (en) 2002-08-14
EP1197211A4 (en) 2004-09-01
NO20020291D0 (no) 2002-01-18
NO20020291L (no) 2002-03-18
CN1374864A (zh) 2002-10-16
WO2001005402A1 (fr) 2001-01-25

Similar Documents

Publication Publication Date Title
ATE327977T1 (de) Tetrahydrochinolin-derivate als crth2 antagonisten
TR199902203T2 (xx) Fernesil transferaz engelleyici, N-veya C-ba�lant�l� imidazoller ile ikame edilmi� 1,8-anele kinolinon t�revleri.
TR199800697T2 (xx) Farmas�tik olarak aktif kinazolin bile�imleri.
HUP0400710A2 (hu) Tioéter helyettesítővel helyettesített imidazokinolinszármazékok, alkalmazásuk és ezeket tartalmazó gyógyszerkészítmények
ATE232520T1 (de) Imidazolidin-4-on derivate verwendbar als antikrebsmittel
TR200103186T2 (tr) MEK enzimlerinin inhibitörleri olarak kinolin türevleri
TR199902606T2 (xx) Farnesil transferaz� engelleyici kinazolinonlar.
BR0113838A (pt) Derivados de n-fenil-2-pirimidina-amina
ATE495187T1 (de) Dalda-analoge und ihre verwendung
DE69924292D1 (de) Pyrazol verbindungen und ihre verwendung
HUP9700005A2 (hu) 2-Ureido-benzamid-származékok és ilyeneket hatóanyagként tartalmazó gyógyszerkészítmények
DE60001586D1 (de) Diphenyl-piperidin derivate
DE69825626D1 (de) Heterozyklische cytotoxische wirkstoffe
IL136359A0 (en) Dihydrobenzofuran derivatives and pharmaceutical compositions containing the same
BG104717A (en) Water soluble azoles as broad-spectrum antifungals
ATE237614T1 (de) Benzo(c)chinolizin derivate,deren herstellung und verwendung als 5-alfa-reduktase inhibitoren
HUP0202340A2 (hu) Hatóanyagként kondenzált heterociklusos vegyületeket tartalmazó gyógyszerkészítmények és alkalmazásuk
DE60009517D1 (de) A-500359-derivate
HUP9901969A2 (hu) N-(merkapto-alkanoil)-cisztein-származékok alkalmazása ischemia kezelésére szolgáló gyógyszerkészítmények előállítására
DE60119514D1 (de) Amidderivate der 2-amino-3-hydroxy-4-tert-leucyl-amino-5-phenyl-pentansäure
AP9801235A0 (en) Erythromycin derivatives.
DE69829849D1 (de) Streptograminderivate, ihre herstellung und sie enthaltende zubereitungen
MXPA02002007A (es) Compuestos de bencimidazol sustituidos con alcoxi, preparaciones farmaceuticas que contienen los mismos, metodos para usarlos.
ATE228359T1 (de) Hemmung der leukotrienbiosynthese mittels harnstoffderivaten
ATE240329T1 (de) Zytotoxische pyrido(2,3,4-kl)acridinderivate, ihre herstellung und therapeutische verwendung

Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees