HUP0103960A2 - A terápiás fehérjékre adott immunválasz erősségének csökkentésére szolgáló eljárások - Google Patents

A terápiás fehérjékre adott immunválasz erősségének csökkentésére szolgáló eljárások

Info

Publication number
HUP0103960A2
HUP0103960A2 HU0103960A HUP0103960A HUP0103960A2 HU P0103960 A2 HUP0103960 A2 HU P0103960A2 HU 0103960 A HU0103960 A HU 0103960A HU P0103960 A HUP0103960 A HU P0103960A HU P0103960 A2 HUP0103960 A2 HU P0103960A2
Authority
HU
Hungary
Prior art keywords
downmodulating
methods
immune response
therapeutic proteins
proteins
Prior art date
Application number
HU0103960A
Other languages
English (en)
Inventor
Mary Collins
Gary S. Gray
Leon W. Hoyer
Jiahua Qian
Original Assignee
American Red Cross
Genetics Institute Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Red Cross, Genetics Institute Inc. filed Critical American Red Cross
Publication of HUP0103960A2 publication Critical patent/HUP0103960A2/hu
Publication of HUP0103960A3 publication Critical patent/HUP0103960A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HU0103960A 1998-09-21 1999-09-21 Methods of downmodulating the immune response to therapeutic proteins HUP0103960A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15817898A 1998-09-21 1998-09-21
PCT/US1999/021991 WO2000016801A1 (en) 1998-09-21 1999-09-21 Methods of downmodulating the immune response to therapeutic proteins

Publications (2)

Publication Number Publication Date
HUP0103960A2 true HUP0103960A2 (hu) 2002-02-28
HUP0103960A3 HUP0103960A3 (en) 2003-09-29

Family

ID=22566971

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0103960A HUP0103960A3 (en) 1998-09-21 1999-09-21 Methods of downmodulating the immune response to therapeutic proteins

Country Status (21)

Country Link
EP (1) EP1115423A1 (hu)
JP (1) JP2002526455A (hu)
KR (1) KR20010085830A (hu)
CN (1) CN1331602A (hu)
AU (1) AU761206B2 (hu)
BR (1) BR9913991A (hu)
CA (1) CA2343916A1 (hu)
CZ (1) CZ20011021A3 (hu)
EA (1) EA005236B1 (hu)
HK (1) HK1039059A1 (hu)
HU (1) HUP0103960A3 (hu)
IL (1) IL142069A0 (hu)
LT (1) LT4920B (hu)
LV (1) LV12768B (hu)
MX (1) MXPA01002898A (hu)
NO (1) NO20011412L (hu)
NZ (1) NZ511034A (hu)
PL (1) PL346796A1 (hu)
SI (1) SI20626A (hu)
WO (1) WO2000016801A1 (hu)
ZA (1) ZA200103156B (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5397703A (en) 1992-07-09 1995-03-14 Cetus Oncology Corporation Method for generation of antibodies to cell surface molecules
WO2001089564A2 (en) * 2000-05-19 2001-11-29 The Center For Blood Research, Inc. Methods for diagnosing and treating hemostatic disorders by modulating p-selectin activity
WO2005010483A2 (en) * 2003-06-10 2005-02-03 Smiths Detection Inc. Sensor arrangement
GB201508024D0 (en) 2015-05-11 2015-06-24 Haemostatix Ltd Haemostatic compositions

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171569A (en) 1985-03-15 1992-12-15 National Research Development Corporation Factor IX preparations uncontaminated by plasma components or pox virus
AU5772886A (en) 1985-04-12 1986-11-05 Genetics Institute Inc. Novel procoagulant proteins
US5422260A (en) 1986-05-29 1995-06-06 Genetics Institute, Inc. -Legal Affairs Human factor VIII:c muteins
US4994371A (en) 1987-08-28 1991-02-19 Davie Earl W DNA preparation of Christmas factor and use of DNA sequences
FR2657884B1 (fr) 1990-02-05 1994-09-02 Tm Innovation Procede pour la preparation du facteur viii humain et d'analogues du facteur viii.
US5661008A (en) 1991-03-15 1997-08-26 Kabi Pharmacia Ab Recombinant human factor VIII derivatives
US5770197A (en) 1991-06-27 1998-06-23 Bristol-Myers Squibb Company Methods for regulating the immune response using B7 binding molecules and IL4-binding molecules
AU661854B2 (en) 1991-06-27 1995-08-10 Bristol-Myers Squibb Company CTL4A receptor, fusion proteins containing it and uses thereof
WO1993009804A1 (en) 1991-11-18 1993-05-27 The Scripps Research Institute Serine protease derived-polypeptides and anti-peptide antibodies, systems and therapeutic methods for inhibiting coagulation
US5663060A (en) 1992-04-07 1997-09-02 Emory University Hybrid human/animal factor VIII
US5364771A (en) 1992-04-07 1994-11-15 Emory University Hybrid human/porcine factor VIII
US5744446A (en) 1992-04-07 1998-04-28 Emory University Hybrid human/animal factor VIII
US5621039A (en) 1993-06-08 1997-04-15 Hallahan; Terrence W. Factor IX- polymeric conjugates
EP0776217A1 (en) * 1994-08-19 1997-06-04 Novo Nordisk A/S A method of treating a patient with a biologically active compound
WO1996012406A1 (en) * 1994-10-19 1996-05-02 Genetic Therapy, Inc. Gene therapy involving concurrent and repeated administration of adenoviruses and immunosuppressive agents
US5714583A (en) 1995-06-07 1998-02-03 Genetics Institute, Inc. Factor IX purification methods
DK0892643T4 (da) * 1996-03-20 2009-12-14 Bristol Myers Squibb Co Fremgangsmåder til inhibering af et immunrespons ved blokering af GP39/CD40- og CTLA4/CD28/B7-banerne og præparater til anvendelse derved
IL130785A0 (en) * 1997-01-10 2001-01-28 Biogen Inc Use of an anti-cd40l compound in the manufacture of a medicament for treating a patient with an autoimmune disease or chronic immune system disorder and pharmaceutical compositions containing the same
JP2002504910A (ja) * 1997-06-20 2002-02-12 バイオジェン，インコーポレイテッド 治療用タンパク質阻害因子症候群のためのｃｄ１５４遮断治療
US8099877B2 (en) 2009-11-06 2012-01-24 Hexagon Metrology Ab Enhanced position detection for a CMM

Also Published As

Publication number Publication date
HUP0103960A3 (en) 2003-09-29
AU6057899A (en) 2000-04-10
CA2343916A1 (en) 2000-03-30
LV12768B (lv) 2002-06-20
EP1115423A1 (en) 2001-07-18
IL142069A0 (en) 2002-03-10
BR9913991A (pt) 2001-07-03
CN1331602A (zh) 2002-01-16
WO2000016801A9 (en) 2000-10-26
HK1039059A1 (zh) 2002-04-12
LT2001045A (en) 2002-01-25
SI20626A (sl) 2002-02-28
NO20011412L (no) 2001-05-16
EA005236B1 (ru) 2004-12-30
EA200100385A1 (ru) 2001-10-22
NO20011412D0 (no) 2001-03-20
ZA200103156B (en) 2002-07-18
AU761206B2 (en) 2003-05-29
LV12768A (en) 2001-12-20
WO2000016801A1 (en) 2000-03-30
KR20010085830A (ko) 2001-09-07
LT4920B (lt) 2002-06-25
CZ20011021A3 (cs) 2001-10-17
JP2002526455A (ja) 2002-08-20
NZ511034A (en) 2004-03-26
PL346796A1 (en) 2002-02-25
MXPA01002898A (es) 2002-06-04

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