HUP0101715A2 - Eljárások és készítmények reumatoid artritisz kezelésére - Google Patents

Eljárások és készítmények reumatoid artritisz kezelésére

Info

Publication number
HUP0101715A2
HUP0101715A2 HU0101715A HUP0101715A HUP0101715A2 HU P0101715 A2 HUP0101715 A2 HU P0101715A2 HU 0101715 A HU0101715 A HU 0101715A HU P0101715 A HUP0101715 A HU P0101715A HU P0101715 A2 HUP0101715 A2 HU P0101715A2
Authority
HU
Hungary
Prior art keywords
rheumatoid arthritis
compositions
methods
butyl
general formula
Prior art date
Application number
HU0101715A
Other languages
English (en)
Inventor
Subhashis Banerjee
Teresa Barlozzari
Andreas Haupt
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of HUP0101715A2 publication Critical patent/HUP0101715A2/hu
Publication of HUP0101715A3 publication Critical patent/HUP0101715A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A találmány tárgyát az R1 R2 N-CHX-CO-A-B-D-(E)S-(F)t-(G)u-K (I)általános képletű vegyületek - ahol R1 és R2 metil- vagy etilcsoport;X izopropil-, szek-butil- vagy terc-butilcsoport; s, t és u értéke 0vagy 1; A, B, D, E, F és G jelentése egymástól függetlenül valamilyenaminosavmaradék; K -R5-N-R6 általános képletű csoport, amelyben R5 ésR6 különböző, egyvegyértékű csoportot jelentenek -ésgyógyszerészetileg elfogadható sóik, valamint ezeket tartalmazógyógyszerkészítmények képezik. A találmány szerinti vegyületek aterápiában önmagukban vagy más artritisz-ellenes hatóanyagokkalkombinálva emlősben (például emberben) a reumatoid artritisztüneteinek megszüntetésére vagy mérséklésére alkalmazhatók. Ó
HU0101715A 1997-10-06 1998-09-24 Methods and compositions for treating rheumatoid arthritis HUP0101715A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/944,479 US6015790A (en) 1997-10-06 1997-10-06 Methods and compositions for treating rheumatoid arthritis
PCT/US1998/019841 WO1999017792A1 (en) 1997-10-06 1998-09-24 Methods and compositions for treating rheumatoid arthritis

Publications (2)

Publication Number Publication Date
HUP0101715A2 true HUP0101715A2 (hu) 2001-11-28
HUP0101715A3 HUP0101715A3 (en) 2001-12-28

Family

ID=25481479

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0101715A HUP0101715A3 (en) 1997-10-06 1998-09-24 Methods and compositions for treating rheumatoid arthritis

Country Status (24)

Country Link
US (1) US6015790A (hu)
EP (1) EP1021200B1 (hu)
JP (1) JP2001518515A (hu)
KR (1) KR20010081900A (hu)
CN (1) CN1278734A (hu)
AR (1) AR017298A1 (hu)
AT (1) ATE212855T1 (hu)
AU (2) AU748465B2 (hu)
BG (1) BG104292A (hu)
BR (1) BR9812875A (hu)
CA (1) CA2305688A1 (hu)
DE (1) DE69803792D1 (hu)
DK (1) DK1021200T3 (hu)
ES (1) ES2173626T3 (hu)
HR (1) HRP20000265A2 (hu)
HU (1) HUP0101715A3 (hu)
IL (1) IL135167A0 (hu)
NO (1) NO20001758L (hu)
PL (1) PL339731A1 (hu)
PT (1) PT1021200E (hu)
SK (1) SK4272000A3 (hu)
TR (1) TR200000903T2 (hu)
WO (2) WO1999017792A1 (hu)
ZA (1) ZA989036B (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010009901A1 (en) * 1996-12-11 2001-07-26 Basf Aktiengesellschaft Germany Antineoplastic peptides
KR100261114B1 (ko) * 1998-01-24 2000-07-01 박종헌 히스톤을 함유하는 류마티스 관절염 치료제 조성물
CA2383026A1 (en) * 1999-09-14 2001-03-22 Pfizer Products Inc. Combination treatment with il-1ra and compounds that inhibit il-1 processing and release
WO2001041789A1 (fr) * 1999-12-07 2001-06-14 Santen Pharmaceutical Co., Ltd. Medicament contre les rhumatismes contenant un derive tetrapeptidique en tant qu'ingredient actif
ES2270898T3 (es) 1999-12-24 2007-04-16 F. Hoffmann-La Roche Ag Derivados de nitrilo como inhibidores de catepsina k.
BRPI0720884A2 (pt) * 2007-01-09 2014-03-25 Bayer Schering Pharma Ag Radiorrotulação por meio de fluoração de aziridinas
US8748370B2 (en) 2009-06-18 2014-06-10 Strongbone Ab Peptide derivatives for treatment, prevention or alleviation of a condition associated with bone loss or low bone density or to inhibit osteoclast differentiation and stimulation
JP6114313B2 (ja) * 2013-01-11 2017-05-24 富士フイルム株式会社 含窒素複素環化合物またはその塩
KR102372512B1 (ko) * 2017-11-20 2022-03-10 가톨릭대학교 산학협력단 폴리감마글루탐산 및 메토트렉세이트를 유효성분으로 포함하는 관절염 예방 또는 치료용 조성물
CN115281149A (zh) * 2021-05-12 2022-11-04 四川大学华西医院 一种临床前类风湿关节炎(Pre-RA)小鼠模型

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816444A (en) * 1987-07-10 1989-03-28 Arizona Board Of Regents, Arizona State University Cell growth inhibitory substance
US4879278A (en) * 1989-05-16 1989-11-07 Arizona Board Of Regents Isolation and structural elucidation of the cytostatic linear depsipeptide dolastatin 15
WO1993003054A1 (en) * 1991-08-09 1993-02-18 Teikoku Hormone Mfg. Co., Ltd. Novel tetrapeptide derivative
US5831002A (en) * 1992-05-20 1998-11-03 Basf Aktiengesellschaft Antitumor peptides
EP0674652B1 (en) * 1992-12-16 2000-09-13 Basf Aktiengesellschaft Dolastatin analog
US5504191A (en) * 1994-08-01 1996-04-02 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory pentapeptide methyl esters
US5530097A (en) * 1994-08-01 1996-06-25 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory peptide amides
US5583153A (en) * 1994-10-06 1996-12-10 Regents Of The University Of California Use of taxol in the treatment of rheumatoid arthritis

Also Published As

Publication number Publication date
SK4272000A3 (en) 2001-02-12
IL135167A0 (en) 2001-05-20
CA2305688A1 (en) 1999-04-15
ATE212855T1 (de) 2002-02-15
AU9592698A (en) 1999-04-27
PL339731A1 (en) 2001-01-02
CN1278734A (zh) 2001-01-03
HUP0101715A3 (en) 2001-12-28
DK1021200T3 (da) 2002-05-27
NO20001758D0 (no) 2000-04-05
WO1999017709A2 (en) 1999-04-15
ES2173626T3 (es) 2002-10-16
US6015790A (en) 2000-01-18
BR9812875A (pt) 2000-08-08
TR200000903T2 (tr) 2001-07-23
NO20001758L (no) 2000-06-05
BG104292A (en) 2000-12-29
KR20010081900A (ko) 2001-08-29
WO1999017792A1 (en) 1999-04-15
AU9502498A (en) 1999-04-27
PT1021200E (pt) 2002-07-31
HRP20000265A2 (en) 2000-12-31
AR017298A1 (es) 2001-09-05
DE69803792D1 (de) 2002-03-21
ZA989036B (en) 2000-04-05
EP1021200A1 (en) 2000-07-26
AU748465B2 (en) 2002-06-06
JP2001518515A (ja) 2001-10-16
EP1021200B1 (en) 2002-02-06

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