HUP0002966A3 - 2-imidazolinylaminobenzoxazole compounds useful as alpha-2 adrenoceptor agonists - Google Patents

2-imidazolinylaminobenzoxazole compounds useful as alpha-2 adrenoceptor agonists

Info

Publication number
HUP0002966A3
HUP0002966A3 HU0002966A HUP0002966A HUP0002966A3 HU P0002966 A3 HUP0002966 A3 HU P0002966A3 HU 0002966 A HU0002966 A HU 0002966A HU P0002966 A HUP0002966 A HU P0002966A HU P0002966 A3 HUP0002966 A3 HU P0002966A3
Authority
HU
Hungary
Prior art keywords
imidazolinylaminobenzoxazole
alpha
compounds useful
adrenoceptor agonists
adrenoceptor
Prior art date
Application number
HU0002966A
Other languages
Hungarian (hu)
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of HUP0002966A2 publication Critical patent/HUP0002966A2/en
Publication of HUP0002966A3 publication Critical patent/HUP0002966A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HU0002966A 1996-11-25 1997-11-21 2-imidazolinylaminobenzoxazole compounds useful as alpha-2 adrenoceptor agonists HUP0002966A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3178796P 1996-11-25 1996-11-25
PCT/US1997/020803 WO1998023611A1 (en) 1996-11-25 1997-11-21 2-imidazolinylaminobenzoxazole compounds useful as alpha-2 adrenoceptor agonists

Publications (2)

Publication Number Publication Date
HUP0002966A2 HUP0002966A2 (en) 2001-09-28
HUP0002966A3 true HUP0002966A3 (en) 2001-10-29

Family

ID=21861392

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0002966A HUP0002966A3 (en) 1996-11-25 1997-11-21 2-imidazolinylaminobenzoxazole compounds useful as alpha-2 adrenoceptor agonists

Country Status (18)

Country Link
US (1) US6110952A (en)
EP (1) EP0944622A1 (en)
JP (1) JP2001506601A (en)
KR (1) KR20000069128A (en)
AU (1) AU736992B2 (en)
BR (1) BR9713537A (en)
CA (1) CA2272683A1 (en)
CO (1) CO4910150A1 (en)
CZ (1) CZ183699A3 (en)
HU (1) HUP0002966A3 (en)
ID (1) ID22060A (en)
IL (1) IL130094A (en)
NO (1) NO313755B1 (en)
PE (1) PE16599A1 (en)
SK (1) SK74999A3 (en)
TR (1) TR199901486T2 (en)
WO (1) WO1998023611A1 (en)
ZA (1) ZA9710579B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL130094A (en) * 1996-11-25 2001-09-13 Procter & Gamble 2-imidazolinylaminobenzoxazole compounds useful as alpha -2 adrenoceptor agonists and pharmaceutical compositions comprising them
AU3864000A (en) * 1999-03-05 2000-09-21 Trustees Of University Technology Corporation, The Inhibitors of serine protease activity, methods and compositions for treatment of herpes viruses
US9051342B2 (en) * 2004-10-13 2015-06-09 Ptc Therapeutics, Inc. Pyrazole or triazole compounds and their use for the manufacture of a medicament for treating somatic mutation related diseases
CN101355876B (en) 2005-11-09 2012-09-05 康宾纳特克斯公司 Compositions for the eye adminstration
US20100203165A1 (en) 2008-08-01 2010-08-12 Gerald Horn Compositions and methods for treatment of disorders or conditions of the eye
US20110003823A1 (en) * 2008-08-01 2011-01-06 Alpha Synergy Development, Inc. Compositions and methods for treatment of diseases and conditions associated with vasodilation and/or vascular leakage
US20100197694A1 (en) * 2008-08-01 2010-08-05 Gerald Horn Compositions and methods for treatment of diseases and conditions with increased vascular permeability
US20100202979A1 (en) * 2008-08-01 2010-08-12 Gerald Horn Compositions and methods for treatment of pulmonary diseases and conditions
US8952011B2 (en) 2008-08-01 2015-02-10 Eye Therapies Llc Compositions and methods for the treatment of nasal conditions
WO2010014552A1 (en) 2008-08-01 2010-02-04 Alpha Synergy Development, Inc. Vasoconstriction compositions and methods of use
US8555875B2 (en) * 2008-12-23 2013-10-15 Map Pharmaceuticals, Inc. Inhalation devices and related methods for administration of sedative hypnotic compounds
US8987270B2 (en) 2009-07-27 2015-03-24 Eye Therapies Llc Formulations of selective alpha-2 agonists and methods of use thereof
JP6052685B2 (en) * 2011-07-25 2016-12-27 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ N- (imidazolidine-2-ylidene) -heterocyclopenta [b] pyridine derivatives as modulators of α2 adrenergic receptors

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795970A (en) * 1972-02-29 1973-08-27 Pfizer NEW DERIVATIVES OF QUINOLEINE, QUINOXALINE AND QUINAZOLINE ER PHARMACEUTICAL COMPOSITION CONTAINING THEM
US3830804A (en) * 1972-11-20 1974-08-20 Eastman Kodak Co Fluorescent(pyrimidinotriazolyl)-2-styrylbenzoxazoles
US4398028A (en) * 1977-01-14 1983-08-09 Sandoz Ltd. Bicyclic heterocyclic amino derivatives
FR2521140A1 (en) * 1982-02-05 1983-08-12 Synthelabo IMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
US5091528A (en) * 1990-09-12 1992-02-25 Allergan, Inc. 6- or 7- (2-imino-2-imidazolidine)-1,4-benzoxazines as α adrenergic agents
GB9110017D0 (en) * 1991-05-09 1991-07-03 Nat Res Dev Spectroscopic investigation using organometallic compounds
JP3805360B2 (en) * 1994-01-24 2006-08-02 アラーガン、インコーポレイテッド α ▲ Lower 2A ▼ Aromatic 2-amino-imidazole derivatives as adrenergic receptor agonists
EP0775134A4 (en) * 1994-08-04 1997-08-13 Synaptic Pharma Corp Novel benzimidazole derivatives
KR100215541B1 (en) * 1996-04-19 1999-08-16 박원훈 Benzoxazole nonlinear optical derivatives and polymers obtained from them
IL130094A (en) * 1996-11-25 2001-09-13 Procter & Gamble 2-imidazolinylaminobenzoxazole compounds useful as alpha -2 adrenoceptor agonists and pharmaceutical compositions comprising them

Also Published As

Publication number Publication date
CA2272683A1 (en) 1998-06-04
ZA9710579B (en) 1998-06-25
KR20000069128A (en) 2000-11-25
NO313755B1 (en) 2002-11-25
IL130094A0 (en) 2000-02-29
BR9713537A (en) 2000-03-21
ID22060A (en) 1999-08-26
PE16599A1 (en) 1999-03-12
EP0944622A1 (en) 1999-09-29
CO4910150A1 (en) 2000-04-24
NO992500D0 (en) 1999-05-25
CZ183699A3 (en) 1999-09-15
AU736992B2 (en) 2001-08-09
JP2001506601A (en) 2001-05-22
WO1998023611A1 (en) 1998-06-04
SK74999A3 (en) 2000-02-14
TR199901486T2 (en) 1999-10-21
HUP0002966A2 (en) 2001-09-28
IL130094A (en) 2001-09-13
AU5438298A (en) 1998-06-22
NO992500L (en) 1999-07-26
US6110952A (en) 2000-08-29

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