HUP0002669A2 - Diabetes kezelése dioxo-tiazolidinnel és szulfonil-karbamiddal - Google Patents
Diabetes kezelése dioxo-tiazolidinnel és szulfonil-karbamiddalInfo
- Publication number
- HUP0002669A2 HUP0002669A2 HU0002669A HUP0002669A HUP0002669A2 HU P0002669 A2 HUP0002669 A2 HU P0002669A2 HU 0002669 A HU0002669 A HU 0002669A HU P0002669 A HUP0002669 A HU P0002669A HU P0002669 A2 HUP0002669 A2 HU P0002669A2
- Authority
- HU
- Hungary
- Prior art keywords
- diabetes
- sulphonylurea
- thiazolidinedione
- treatment
- insulin
- Prior art date
Links
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 2
- ZOBPZXTWZATXDG-UHFFFAOYSA-N 1,3-thiazolidine-2,4-dione Chemical compound O=C1CSC(=O)N1 ZOBPZXTWZATXDG-UHFFFAOYSA-N 0.000 title 1
- 229940123464 Thiazolidinedione Drugs 0.000 title 1
- YROXIXLRRCOBKF-UHFFFAOYSA-N sulfonylurea Chemical compound OC(=N)N=S(=O)=O YROXIXLRRCOBKF-UHFFFAOYSA-N 0.000 title 1
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
- 102000004877 Insulin Human genes 0.000 abstract 1
- 108090001061 Insulin Proteins 0.000 abstract 1
- 229940122199 Insulin secretagogue Drugs 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940125396 insulin Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 231100000489 sensitizer Toxicity 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A találmány diabetes mellitus, különösen II. típusú diabetes, valamintdiabetes mellitusszal kapcsolatos állapotok emlősökben végzettkezelési eljárására vonatkozik, amelynek során egy ilyen kezeléstigénylő emlősnek beadják egy inzulinszenzibilizátor, például 5-[4-{2-[N-metil-N-(2-piridil)-amino]-etoxi}-benzil]-2,4-dioxo-tiazolidin,(+)-5-{4-[(3,4-dihidro-6-hidroxi-2,5,7,8-tetrametil-2H-1-benzopirán-2-il)-metoxi]-benzil}-2,4-dioxo-tiazolidin vagy troglitazon, 5-{4-[(1-metil-ciklohexil)-metoxi]-benzil}-2,4-dioxo-tiazolidin vagyciglitazon, 5-{4-[2-(5-etil-2-piridil)-etoxi]-benzil}-2,4-dioxo-tiazolidin vagy pioglitazon vagy 5-[(2-benzil-2,3-dihidro-5-benzopiranil)-metil]-2,4-dioxo-tiazolidin vagy englitazon, és egyinzulinsecretagogum, így egy szulfonil-karbamid, például glibenklamid,glipizid, gliklazid, glimepirid, tolazamid vagy tolbutamid hatásos,nemtoxikus és gyógyászatilag elfogadható mennyiségét. Ó
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9806710.1A GB9806710D0 (en) | 1998-03-27 | 1998-03-27 | Novel method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0002669A2 true HUP0002669A2 (hu) | 2000-12-28 |
| HUP0002669A3 HUP0002669A3 (en) | 2001-12-28 |
Family
ID=10829475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0002669A HUP0002669A3 (en) | 1998-03-27 | 1998-06-15 | Treatment of diabetes with thiazolidinedione and sulphonylurea |
Country Status (2)
| Country | Link |
|---|---|
| GB (1) | GB9806710D0 (hu) |
| HU (1) | HUP0002669A3 (hu) |
-
1998
- 1998-03-27 GB GBGB9806710.1A patent/GB9806710D0/en not_active Ceased
- 1998-06-15 HU HU0002669A patent/HUP0002669A3/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB9806710D0 (en) | 1998-05-27 |
| HUP0002669A3 (en) | 2001-12-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |