HUP0001434A3 - 5,7-disubstituted 4-aminopyrido[2,3-d]pyrimidine compounds, pharmaceutical compouads thereof and process for their preparation - Google Patents
5,7-disubstituted 4-aminopyrido[2,3-d]pyrimidine compounds, pharmaceutical compouads thereof and process for their preparationInfo
- Publication number
- HUP0001434A3 HUP0001434A3 HU0001434A HUP0001434A HUP0001434A3 HU P0001434 A3 HUP0001434 A3 HU P0001434A3 HU 0001434 A HU0001434 A HU 0001434A HU P0001434 A HUP0001434 A HU P0001434A HU P0001434 A3 HUP0001434 A3 HU P0001434A3
- Authority
- HU
- Hungary
- Prior art keywords
- compouads
- aminopyrido
- disubstituted
- pharmaceutical
- preparation
- Prior art date
Links
- -1 5,7-disubstituted 4-aminopyrido[2,3-d]pyrimidine compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83821697A | 1997-04-16 | 1997-04-16 | |
PCT/US1998/007207 WO1998046605A1 (en) | 1997-04-16 | 1998-04-14 | 5,7-disubstituted 4-aminopyrido[2,3-d]pyrimidine compounds and their use as adenosine kinase inhibitors |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0001434A2 HUP0001434A2 (hu) | 2000-10-28 |
HUP0001434A3 true HUP0001434A3 (en) | 2001-01-29 |
Family
ID=25276561
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0001434A HUP0001434A3 (en) | 1997-04-16 | 1998-04-14 | 5,7-disubstituted 4-aminopyrido[2,3-d]pyrimidine compounds, pharmaceutical compouads thereof and process for their preparation |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0989986A1 (hu) |
JP (1) | JP2001520655A (hu) |
KR (1) | KR20010006509A (hu) |
CN (1) | CN1252070A (hu) |
AR (1) | AR012436A1 (hu) |
AU (1) | AU7108398A (hu) |
BG (1) | BG103842A (hu) |
BR (1) | BR9809055A (hu) |
CA (1) | CA2286909A1 (hu) |
CO (1) | CO4940446A1 (hu) |
HU (1) | HUP0001434A3 (hu) |
IL (1) | IL131618A0 (hu) |
NO (1) | NO995036D0 (hu) |
PL (1) | PL336304A1 (hu) |
SK (1) | SK141799A3 (hu) |
TR (1) | TR199902455T2 (hu) |
WO (1) | WO1998046605A1 (hu) |
ZA (1) | ZA983177B (hu) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000023444A1 (en) * | 1998-10-21 | 2000-04-27 | Abbott Laboratories | 5,7-disubstituted-4-aminopyrido[2,3-d]pyrimidine compounds |
HU229604B1 (en) | 2001-02-12 | 2014-02-28 | Hoffmann La Roche | 6-substituted pyrido-pyrimidines, process for their preparation and pharmaceutical compositions containing them |
KR20040085151A (ko) | 2002-01-17 | 2004-10-07 | 뉴로젠 코포레이션 | 캡사이신 조절자로서의 치환된 퀴나졸린-4-일 아민 유사체 |
DE10335183A1 (de) * | 2003-07-30 | 2005-02-24 | Bayer Cropscience Ag | Fungizide Wirkstoffkombinationen |
CN101243081A (zh) * | 2005-07-21 | 2008-08-13 | 霍夫曼-拉罗奇有限公司 | 作为PTP1B抑制剂的吡啶并[2,3-d]嘧啶-2,4-二胺化合物 |
WO2007081517A2 (en) | 2005-12-21 | 2007-07-19 | Abbott Laboratories | Anti-viral compounds |
KR20080080395A (ko) * | 2005-12-21 | 2008-09-03 | 아보트 러보러터리즈 | 항바이러스 화합물 |
US8236950B2 (en) | 2006-12-20 | 2012-08-07 | Abbott Laboratories | Anti-viral compounds |
WO2009029632A1 (en) * | 2007-08-27 | 2009-03-05 | Helicon Therapeutics, Inc. | Therapeutic isoxazole compounds |
MX2010002098A (es) | 2007-08-31 | 2010-03-30 | Eisai R&D Man Co Ltd | Compuesto policiclico. |
DE102007061764A1 (de) * | 2007-12-20 | 2009-06-25 | Bayer Healthcare Ag | Anellierte Cyanopyridine und ihre Verwendung |
CN102333777B (zh) * | 2009-02-26 | 2014-06-25 | 卫材R&D管理有限公司 | 含氮的稠合杂环化合物及其作为β淀粉样蛋白生成抑制剂的用途 |
WO2014055595A1 (en) | 2012-10-05 | 2014-04-10 | Merck Sharp & Dohme Corp. | Indoline compounds as aldosterone synthase inhibitiors related applications |
KR102375929B1 (ko) | 2016-03-31 | 2022-03-16 | 온크터널 테라퓨틱스, 인코포레이티드. | 인돌린 유사체 및 이의 용도 |
CN110256420B (zh) * | 2019-05-07 | 2020-04-28 | 江西中医药大学 | 四氢吡啶并嘧啶衍生物及其制备方法和用途 |
CN110283171A (zh) * | 2019-07-17 | 2019-09-27 | 鼎泰(南京)临床医学研究有限公司 | 一类含有吡啶并嘧啶-4-胺类结构的化合物、药物组合物以及其应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5324731A (en) * | 1989-02-14 | 1994-06-28 | Amira, Inc. | Method of inhibiting transformation of cells in which purine metabolic enzyme activity is elevated |
IL112249A (en) * | 1994-01-25 | 2001-11-25 | Warner Lambert Co | Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds |
US6143749A (en) * | 1995-06-07 | 2000-11-07 | Abbott Laboratories | Heterocyclic substituted cyclopentane compounds |
-
1998
- 1998-04-14 IL IL13161898A patent/IL131618A0/xx unknown
- 1998-04-14 JP JP54408898A patent/JP2001520655A/ja active Pending
- 1998-04-14 HU HU0001434A patent/HUP0001434A3/hu unknown
- 1998-04-14 CN CN98804151A patent/CN1252070A/zh active Pending
- 1998-04-14 BR BR9809055-0A patent/BR9809055A/pt not_active Application Discontinuation
- 1998-04-14 EP EP98918093A patent/EP0989986A1/en not_active Withdrawn
- 1998-04-14 KR KR1019997009599A patent/KR20010006509A/ko not_active Application Discontinuation
- 1998-04-14 AU AU71083/98A patent/AU7108398A/en not_active Abandoned
- 1998-04-14 TR TR1999/02455T patent/TR199902455T2/xx unknown
- 1998-04-14 SK SK1417-99A patent/SK141799A3/sk unknown
- 1998-04-14 CA CA002286909A patent/CA2286909A1/en not_active Abandoned
- 1998-04-14 WO PCT/US1998/007207 patent/WO1998046605A1/en not_active Application Discontinuation
- 1998-04-14 PL PL98336304A patent/PL336304A1/xx unknown
- 1998-04-15 AR ARP980101733A patent/AR012436A1/es unknown
- 1998-04-15 ZA ZA983177A patent/ZA983177B/xx unknown
- 1998-04-16 CO CO98020979A patent/CO4940446A1/es unknown
-
1999
- 1999-10-15 NO NO995036A patent/NO995036D0/no not_active Application Discontinuation
- 1999-10-29 BG BG103842A patent/BG103842A/xx active Pending
Also Published As
Publication number | Publication date |
---|---|
WO1998046605A1 (en) | 1998-10-22 |
EP0989986A1 (en) | 2000-04-05 |
CA2286909A1 (en) | 1998-10-22 |
NO995036L (no) | 1999-10-15 |
CO4940446A1 (es) | 2000-07-24 |
CN1252070A (zh) | 2000-05-03 |
PL336304A1 (en) | 2000-06-19 |
ZA983177B (en) | 1999-01-22 |
NO995036D0 (no) | 1999-10-15 |
BG103842A (en) | 2000-06-30 |
AU7108398A (en) | 1998-11-11 |
SK141799A3 (en) | 2000-08-14 |
HUP0001434A2 (hu) | 2000-10-28 |
BR9809055A (pt) | 2000-08-08 |
TR199902455T2 (xx) | 2000-01-21 |
KR20010006509A (ko) | 2001-01-26 |
AR012436A1 (es) | 2000-10-18 |
JP2001520655A (ja) | 2001-10-30 |
IL131618A0 (en) | 2001-01-28 |
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