HUP0000523A2 - Éterlipid/kiegészítő alakú lipid kombinációt tartalmazó hordozók és terápiai alkalmazásuk - Google Patents
Éterlipid/kiegészítő alakú lipid kombinációt tartalmazó hordozók és terápiai alkalmazásukInfo
- Publication number
- HUP0000523A2 HUP0000523A2 HU0000523A HUP0000523A HUP0000523A2 HU P0000523 A2 HUP0000523 A2 HU P0000523A2 HU 0000523 A HU0000523 A HU 0000523A HU P0000523 A HUP0000523 A HU P0000523A HU P0000523 A2 HUP0000523 A2 HU P0000523A2
- Authority
- HU
- Hungary
- Prior art keywords
- entherlipid
- therapeutic uses
- carriers containing
- lipid combination
- shape lipid
- Prior art date
Links
- 150000002632 lipids Chemical class 0.000 title abstract 2
- 239000000969 carrier Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 238000002360 preparation method Methods 0.000 abstract 2
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000031513 cyst Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 150000002313 glycerolipids Chemical class 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 229930195734 saturated hydrocarbon Natural products 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 229930195735 unsaturated hydrocarbon Natural products 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
Abstract
A találmány általánős képletű glicerőlipidből, a képletben R1jelentése telített vagy telítetlen szénhidrőgénlánc és Z jelentéseőxigén- vagy kénatőm, és kiegészítő alakú lipidből álló hőrdőzóttartalmazó gyógyászati készítményekre, valamint a készítményekkülönböző rendellenességek, példáűl rák és gyűlladásős állapőtőkkezelésére való alkalmazására vőnatkőzik. ŕ
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/720,997 US5932242A (en) | 1996-10-15 | 1996-10-15 | Ether lipid-containing pharmaceutical compositions and therapeutic uses thereof |
PCT/US1997/018546 WO1998016200A1 (en) | 1996-10-15 | 1997-10-15 | Carriers containing an etherlipid/complementarily shape lipid combination and therapeutic uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0000523A2 true HUP0000523A2 (hu) | 2000-09-28 |
HUP0000523A3 HUP0000523A3 (en) | 2000-10-30 |
Family
ID=24896093
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0000523A HUP0000523A3 (en) | 1996-10-15 | 1997-10-15 | Carriers containing an entherlipid/complementarily shape lipid combination and therapeutic uses thereof |
Country Status (18)
Country | Link |
---|---|
US (2) | US5932242A (hu) |
EP (1) | EP0966266A4 (hu) |
JP (1) | JP2001502332A (hu) |
KR (1) | KR100512689B1 (hu) |
CN (1) | CN1088582C (hu) |
AU (1) | AU722092B2 (hu) |
BR (1) | BR9712329A (hu) |
CA (1) | CA2268841A1 (hu) |
CZ (1) | CZ131799A3 (hu) |
HK (1) | HK1024638A1 (hu) |
HU (1) | HUP0000523A3 (hu) |
IL (1) | IL129473A0 (hu) |
NO (1) | NO991770L (hu) |
NZ (1) | NZ335125A (hu) |
PL (1) | PL190711B1 (hu) |
SK (1) | SK283817B6 (hu) |
TR (1) | TR199900799T2 (hu) |
WO (1) | WO1998016200A1 (hu) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6667053B1 (en) | 1996-02-16 | 2003-12-23 | Elan Pharmaceuticals, Inc. | D and L etherlipid stereoisomers and liposomes |
DE19829448A1 (de) * | 1998-07-01 | 2000-10-12 | Medmark Pharma Gmbh | 1-Octadecyl-2-methyl-sn-glycero-3-phosphocholin (ET180CH3) zur Behandlung von humanen Mammakarzinomen |
WO2004062586A2 (en) * | 2003-01-09 | 2004-07-29 | Zeneus Pharma Limited | Antineoplastic ether lipid compounds |
EP1587518A4 (en) * | 2003-01-09 | 2008-08-20 | Zeneus Pharma Ltd | ANTINEOPLASTIC LIPIDIC ETHER COMPOUNDS HAVING MODIFICATIONS AT THE CARBON GROUP SN-3 |
WO2004065719A2 (en) * | 2003-01-16 | 2004-08-05 | Hunter Douglas Inc. | Covering for architectural surfaces and method of forming and applying same |
ATE433979T1 (de) | 2004-04-02 | 2009-07-15 | Osi Pharm Inc | Mit einem 6,6-bicyclischen ring substituierte heterobicyclische proteinkinaseinhibitoren |
US8828972B2 (en) | 2004-10-19 | 2014-09-09 | Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. | Formulations containing alkylphosphocholines using novel negative charge carriers |
JP5382974B2 (ja) * | 2005-03-11 | 2014-01-08 | 太陽化学株式会社 | 化粧料用組成物及び化粧料 |
KR100829595B1 (ko) | 2006-12-11 | 2008-05-14 | 한국화학연구원 | 당이 결합된 인지질로 수식된 리포솜 및 이의 제조방법 |
DK2536414T3 (en) | 2010-02-18 | 2016-10-03 | Inserm (Institut Nat De La Santé Et De La Rech Médicale) | METHOD FOR PREVENTING cancer metastasis |
CA3047023C (en) * | 2016-12-14 | 2022-05-31 | Beijing Showby Pharmaceutical Co., Ltd. | Class of bifunctional compounds with quaternary ammonium salt structure |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2009343C3 (de) * | 1970-02-27 | 1980-10-23 | Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen | Verwendung von Lysolecithinen als immunologische Adjuvantien |
GB2046092B (en) * | 1979-03-05 | 1983-11-02 | Toyama Chemical Co Ltd | Pharmaceutical composition containing a lysophospholid and a phospholipid |
JPS5772914A (en) * | 1980-10-22 | 1982-05-07 | Takeda Chem Ind Ltd | Antitumor agent |
DE3239858A1 (de) * | 1982-07-06 | 1984-01-12 | Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Neue d-mannitderivate als ausgangsprodukte zur synthese von phospholipiden |
US5169637A (en) * | 1983-03-24 | 1992-12-08 | The Liposome Company, Inc. | Stable plurilamellar vesicles |
US4983397A (en) * | 1985-08-19 | 1991-01-08 | Board Of Regents, University Of Texas System | Pharmaceutical compositions consisting of acylated phospholipids |
US5260284A (en) * | 1987-02-17 | 1993-11-09 | Board Of Regents, The University Of Texas System | Methods employing unique mixtures of polar and neutral lipids and sterol for lung surfactant replacement therapy |
US4965391A (en) * | 1987-10-23 | 1990-10-23 | The University Of Michigan | Radioiodinated phospholipid ether analogues |
US5077057A (en) * | 1989-04-05 | 1991-12-31 | The Regents Of The University Of California | Preparation of liposome and lipid complex compositions |
DE4132345A1 (de) * | 1991-09-27 | 1993-04-01 | Max Planck Gesellschaft | Ether-lysolecithine und alkylphosphocholine in liposomen |
EP0785773B1 (en) * | 1994-10-14 | 2001-01-03 | The Liposome Company, Inc. | Ether lipid liposomes and their therapeutic use |
-
1996
- 1996-10-15 US US08/720,997 patent/US5932242A/en not_active Expired - Fee Related
-
1997
- 1997-10-15 CA CA002268841A patent/CA2268841A1/en not_active Abandoned
- 1997-10-15 CN CN97180612A patent/CN1088582C/zh not_active Expired - Fee Related
- 1997-10-15 WO PCT/US1997/018546 patent/WO1998016200A1/en not_active Application Discontinuation
- 1997-10-15 JP JP10518533A patent/JP2001502332A/ja not_active Ceased
- 1997-10-15 BR BR9712329-3A patent/BR9712329A/pt not_active Application Discontinuation
- 1997-10-15 HU HU0000523A patent/HUP0000523A3/hu unknown
- 1997-10-15 IL IL12947397A patent/IL129473A0/xx unknown
- 1997-10-15 NZ NZ335125A patent/NZ335125A/xx unknown
- 1997-10-15 PL PL97332696A patent/PL190711B1/pl not_active IP Right Cessation
- 1997-10-15 EP EP97910107A patent/EP0966266A4/en not_active Withdrawn
- 1997-10-15 SK SK493-99A patent/SK283817B6/sk unknown
- 1997-10-15 KR KR10-1999-7003214A patent/KR100512689B1/ko not_active IP Right Cessation
- 1997-10-15 AU AU47567/97A patent/AU722092B2/en not_active Ceased
- 1997-10-15 US US08/950,773 patent/US6017557A/en not_active Expired - Fee Related
- 1997-10-15 CZ CZ991317A patent/CZ131799A3/cs unknown
- 1997-10-15 TR TR1999/00799T patent/TR199900799T2/xx unknown
-
1999
- 1999-04-14 NO NO991770A patent/NO991770L/no not_active Application Discontinuation
-
2000
- 2000-07-04 HK HK00104072A patent/HK1024638A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CN1088582C (zh) | 2002-08-07 |
CA2268841A1 (en) | 1998-04-23 |
HK1024638A1 (en) | 2000-10-20 |
HUP0000523A3 (en) | 2000-10-30 |
AU722092B2 (en) | 2000-07-20 |
PL190711B1 (pl) | 2005-12-30 |
US5932242A (en) | 1999-08-03 |
US6017557A (en) | 2000-01-25 |
NO991770L (no) | 1999-06-09 |
BR9712329A (pt) | 1999-08-31 |
TR199900799T2 (xx) | 1999-07-21 |
SK283817B6 (sk) | 2004-02-03 |
NO991770D0 (no) | 1999-04-14 |
PL332696A1 (en) | 1999-09-27 |
KR100512689B1 (ko) | 2005-09-07 |
CN1240348A (zh) | 2000-01-05 |
AU4756797A (en) | 1998-05-11 |
IL129473A0 (en) | 2000-02-29 |
KR20000049128A (ko) | 2000-07-25 |
JP2001502332A (ja) | 2001-02-20 |
NZ335125A (en) | 1999-11-29 |
EP0966266A4 (en) | 2006-01-11 |
EP0966266A1 (en) | 1999-12-29 |
SK49399A3 (en) | 1999-11-08 |
WO1998016200A1 (en) | 1998-04-23 |
CZ131799A3 (cs) | 1999-08-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees | ||
GB9A | Succession in title |
Owner name: CEPHALON LIMITED, GB Free format text: FORMER OWNER(S): ELAN PHARMACEUTICALS, INC., US; MEDEUS PHARMA LIMITED, GB; THE LIPOSOME COMPANY, INC., US; ZENEUS PHARMA LIMITED, GB |
|
HC9A | Change of name, address |
Owner name: CEPHALON LIMITED, GB Free format text: FORMER OWNER(S): ELAN PHARMACEUTICALS, INC., US; MEDEUS PHARMA LIMITED, GB; THE LIPOSOME COMPANY, INC., US; ZENEUS PHARMA LIMITED, GB |