HUE044772T2 - Immunogén készítmény - Google Patents

Immunogén készítmény

Info

Publication number: HUE044772T2
Authority: HU; Hungary
Prior art keywords: immunogenic composition; immunogenic; composition
Prior art date: 2011-05-27

Application number

Other languages

English (en)

Inventor

Cindy Castado

Original Assignee

Glaxosmithkline Biologicals Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-05-27

Filing date

2012-05-25

Publication date

2019-11-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46168484&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE044772(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2012-05-25 Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa

2019-11-28 Publication of HUE044772T2 publication Critical patent/HUE044772T2/hu

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1282—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Clostridium (G)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Microbiology (AREA)
Biomedical Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biotechnology (AREA)
Zoology (AREA)
General Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Gastroenterology & Hepatology (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

HUE16193340 2011-05-27 2012-05-25 Immunogén készítmény HUE044772T2 (hu)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date
US201161490734P	2011-05-27	2011-05-27
US201161490707P	2011-05-27	2011-05-27
US201161490716P	2011-05-27	2011-05-27

Publications (1)

Publication Number	Publication Date
HUE044772T2 true HUE044772T2 (hu)	2019-11-28

Family

ID=46168484

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
HUE12726374A HUE030823T2 (hu)	2011-05-27	2012-05-25	Immunogén készítmény
HUE12724950A HUE037126T2 (hu)	2011-05-27	2012-05-25	Immunogén készítmény
HUE19179871A HUE064492T2 (hu)	2011-05-27	2012-05-25	Immunogén készítmény
HUE16193340 HUE044772T2 (hu)	2011-05-27	2012-05-25	Immunogén készítmény

Family Applications Before (3)

Application Number	Title	Priority Date	Filing Date
HUE12726374A HUE030823T2 (hu)	2011-05-27	2012-05-25	Immunogén készítmény
HUE12724950A HUE037126T2 (hu)	2011-05-27	2012-05-25	Immunogén készítmény
HUE19179871A HUE064492T2 (hu)	2011-05-27	2012-05-25	Immunogén készítmény

Country Status (25)

Country	Link
US (5)	US9290565B2 (hu)
EP (6)	EP3564378B1 (hu)
JP (3)	JP2014516532A (hu)
KR (1)	KR102014502B1 (hu)
CN (3)	CN107098977A (hu)
BR (2)	BR112013030396A2 (hu)
CA (2)	CA2837395C (hu)
CY (3)	CY1118599T1 (hu)
DK (4)	DK3138916T3 (hu)
EA (1)	EA030898B1 (hu)
ES (4)	ES2615737T3 (hu)
FI (1)	FI3564378T3 (hu)
HR (4)	HRP20231749T1 (hu)
HU (4)	HUE030823T2 (hu)
IL (1)	IL229529B2 (hu)
LT (4)	LT2714910T (hu)
ME (1)	ME02600B (hu)
MX (1)	MX346200B (hu)
PL (4)	PL2714911T3 (hu)
PT (4)	PT3138916T (hu)
RS (1)	RS55605B1 (hu)
SG (1)	SG195037A1 (hu)
SI (4)	SI3564378T1 (hu)
SM (1)	SMT201700110B (hu)
WO (3)	WO2012163811A1 (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR101907434B1 (ko)	2010-09-03	2018-10-12	발네바 오스트리아 게엠베하	C. 디피실의 a 독소 및 b 독소 단백질의 분리된 폴리펩타이드 및 이의 용도
HRP20231631T1 (hr)	2011-04-22	2024-03-15	Wyeth Llc	Pripravci koji se odnose na mutantni toksin iz bakterije clostridium difficile i odgovarajući postupci
SG11201402375VA (en) *	2011-12-08	2014-10-30	Novartis Ag	Clostridium difficile toxin-based vaccine
BR122016023101B1 (pt)	2012-10-21	2022-03-22	Pfizer Inc	Polipeptídeo, composição imunogênica que o compreende, bem como célula recombinante derivada de clostridium difficile
LT2928489T (lt) *	2012-12-05	2019-04-10	Glaxosmithkline Biologicals S.A.	Imunogeninė kompozicija
CA2910200A1 (en) *	2013-04-22	2014-10-30	Board Of Regents Of The University Of Oklahoma	Clostridium difficile vaccine and methods of use
CA2976976C (en)	2015-02-19	2023-02-28	Immune Biosolutions Inc.	Clostridium difficile toxins a and/or b antigen and epitope antibody, and pharmaceutical uses thereof
EP3810163A1 (en) *	2018-06-19	2021-04-28	GlaxoSmithKline Biologicals SA	Immunogenic composition
WO2023020994A1 (en)	2021-08-16	2023-02-23	Glaxosmithkline Biologicals Sa	Novel methods
WO2023020993A1 (en)	2021-08-16	2023-02-23	Glaxosmithkline Biologicals Sa	Novel methods
WO2023020992A1 (en)	2021-08-16	2023-02-23	Glaxosmithkline Biologicals Sa	Novel methods
GB202205833D0 (en)	2022-04-21	2022-06-08	Glaxosmithkline Biologicals Sa	Bacteriophage
WO2023232901A1 (en)	2022-06-01	2023-12-07	Valneva Austria Gmbh	Clostridium difficile vaccine

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4235877A (en)	1979-06-27	1980-11-25	Merck & Co., Inc.	Liposome particle containing viral or bacterial antigenic subunit
US4751180A (en)	1985-03-28	1988-06-14	Chiron Corporation	Expression using fused genes providing for protein product
US4935233A (en)	1985-12-02	1990-06-19	G. D. Searle And Company	Covalently linked polypeptide cell modulators
CZ296806B6 (cs)	1994-10-24	2006-06-14	Allergan, Inc.	Rozpustný fúzní protein a zpusob výroby rozpustného rekombinantního botulinového toxinu
JPH11509200A (ja) *	1995-07-07	1999-08-17	オラバックスインク．	粘膜アジュバントとしてのクロストリジウム・ディフィシール（ＣｌｏｓｔｒｉｄｉｕｍＤｉｆｆｉｃｉｌｅ）トキシン
JP2002542169A (ja) *	1999-04-09	2002-12-10	テクラブ，インコーポレイテッド	Ｃｌｏｓｔｒｉｄｉｕｍｄｉｆｆｉｃｉｌｅに対する、組換え毒素Ａ／毒素Ｂワクチン
EP1165796A2 (en) *	1999-04-09	2002-01-02	Techlab, Inc.	Recombinant clostridium toxin a protein carrier for polysaccharide conjugate vaccines
AU2001251013A1 (en)	2000-03-28	2001-10-08	Diadexus, Inc.	Compositions and methods of diagnosing, monitoring, staging, imaging and treating colon cancer
WO2010017383A1 (en) *	2008-08-06	2010-02-11	Emergent Product Development Uk Limited	Vaccines against clostridium difficile and methods of use
WO2011060431A2 (en) *	2009-11-16	2011-05-19	University Of Maryland Baltimore	Multivalent live vector vaccine against clostridium difficile-associated disease
KR101907434B1 (ko)	2010-09-03	2018-10-12	발네바 오스트리아 게엠베하	C. 디피실의 a 독소 및 b 독소 단백질의 분리된 폴리펩타이드 및 이의 용도
GB201016742D0 (en) *	2010-10-05	2010-11-17	Health Prot Agency	Clostridium difficile antigens

2012
- 2012-05-25 ES ES12726374.7T patent/ES2615737T3/es active Active
- 2012-05-25 PT PT16193340T patent/PT3138916T/pt unknown
- 2012-05-25 LT LTEP12724950.6T patent/LT2714910T/lt unknown
- 2012-05-25 SI SI201232050T patent/SI3564378T1/sl unknown
- 2012-05-25 US US14/122,690 patent/US9290565B2/en not_active Expired - Fee Related
- 2012-05-25 PT PT127249506T patent/PT2714910T/pt unknown
- 2012-05-25 HU HUE12726374A patent/HUE030823T2/hu unknown
- 2012-05-25 MX MX2013013924A patent/MX346200B/es active IP Right Grant
- 2012-05-25 LT LTEP16193340.3T patent/LT3138916T/lt unknown
- 2012-05-25 BR BR112013030396A patent/BR112013030396A2/pt not_active IP Right Cessation
- 2012-05-25 PL PL12726374T patent/PL2714911T3/pl unknown
- 2012-05-25 RS RS20170051A patent/RS55605B1/sr unknown
- 2012-05-25 PT PT191798719T patent/PT3564378T/pt unknown
- 2012-05-25 FI FIEP19179871.9T patent/FI3564378T3/fi active
- 2012-05-25 ES ES19179871T patent/ES2968455T3/es active Active
- 2012-05-25 CA CA2837395A patent/CA2837395C/en active Active
- 2012-05-25 US US14/122,345 patent/US9409974B2/en active Active
- 2012-05-25 WO PCT/EP2012/059793 patent/WO2012163811A1/en active Application Filing
- 2012-05-25 HR HRP20231749TT patent/HRP20231749T1/hr unknown
- 2012-05-25 ME MEP-2017-26A patent/ME02600B/me unknown
- 2012-05-25 DK DK16193340.3T patent/DK3138916T3/da active
- 2012-05-25 PT PT127263747T patent/PT2714911T/pt unknown
- 2012-05-25 PL PL16193340T patent/PL3138916T3/pl unknown
- 2012-05-25 EP EP19179871.9A patent/EP3564378B1/en active Active
- 2012-05-25 LT LTEP12726374.7T patent/LT2714911T/lt unknown
- 2012-05-25 DK DK12724950.6T patent/DK2714910T3/en active
- 2012-05-25 KR KR1020137034795A patent/KR102014502B1/ko active IP Right Grant
- 2012-05-25 CA CA2837393A patent/CA2837393A1/en not_active Abandoned
- 2012-05-25 EP EP12726374.7A patent/EP2714911B1/en not_active Revoked
- 2012-05-25 CN CN201710239709.0A patent/CN107098977A/zh active Pending
- 2012-05-25 LT LTEP19179871.9T patent/LT3564378T/lt unknown
- 2012-05-25 DK DK12726374.7T patent/DK2714911T3/en active
- 2012-05-25 EP EP16193340.3A patent/EP3138916B1/en not_active Revoked
- 2012-05-25 CN CN201280037466.8A patent/CN103732750A/zh active Pending
- 2012-05-25 EP EP23205566.5A patent/EP4296361A3/en active Pending
- 2012-05-25 SI SI201231642T patent/SI3138916T1/sl unknown
- 2012-05-25 EA EA201391548A patent/EA030898B1/ru not_active IP Right Cessation
- 2012-05-25 JP JP2014511895A patent/JP2014516532A/ja active Pending
- 2012-05-25 CN CN201280037472.3A patent/CN103717742B/zh active Active
- 2012-05-25 ES ES16193340T patent/ES2743442T3/es active Active
- 2012-05-25 BR BR112013030395-6A patent/BR112013030395B1/pt active IP Right Grant
- 2012-05-25 PL PL19179871.9T patent/PL3564378T3/pl unknown
- 2012-05-25 PL PL12724950T patent/PL2714910T3/pl unknown
- 2012-05-25 ES ES12724950.6T patent/ES2660468T3/es active Active
- 2012-05-25 SG SG2013085386A patent/SG195037A1/en unknown
- 2012-05-25 DK DK19179871.9T patent/DK3564378T3/da active
- 2012-05-25 WO PCT/EP2012/059805 patent/WO2012163817A2/en active Application Filing
- 2012-05-25 HU HUE12724950A patent/HUE037126T2/hu unknown
- 2012-05-25 EP EP18150735.1A patent/EP3327126A1/en not_active Withdrawn
- 2012-05-25 SI SI201230868A patent/SI2714911T1/sl unknown
- 2012-05-25 HU HUE19179871A patent/HUE064492T2/hu unknown
- 2012-05-25 JP JP2014511899A patent/JP5952390B2/ja active Active
- 2012-05-25 SI SI201231247T patent/SI2714910T1/en unknown
- 2012-05-25 HU HUE16193340 patent/HUE044772T2/hu unknown
- 2012-05-25 EP EP12724950.6A patent/EP2714910B1/en active Active
- 2012-05-25 WO PCT/EP2012/059792 patent/WO2012163810A1/en active Application Filing
2013
- 2013-11-21 IL IL229529A patent/IL229529B2/en unknown
2016
- 2016-02-11 US US15/041,924 patent/US9644024B2/en active Active
- 2016-06-09 JP JP2016114910A patent/JP2017012160A/ja active Pending
- 2016-06-28 US US15/194,937 patent/US10093722B2/en active Active
2017
- 2017-01-20 HR HRP20170094TT patent/HRP20170094T1/hr unknown
- 2017-02-03 CY CY20171100158T patent/CY1118599T1/el unknown
- 2017-02-16 SM SM201700110T patent/SMT201700110B/it unknown
- 2017-03-21 US US15/464,454 patent/US10377816B2/en active Active
2018
- 2018-02-15 CY CY20181100188T patent/CY1119916T1/el unknown
- 2018-02-23 HR HRP20180339TT patent/HRP20180339T1/hr unknown
2019
- 2019-07-17 HR HRP20191291TT patent/HRP20191291T1/hr unknown
- 2019-08-27 CY CY20191100909T patent/CY1121936T1/el unknown

Also Published As

Publication number	Publication date
SI2714910T1 (en)	2018-04-30
PL3138916T3 (pl)	2019-11-29
EP2714911A2 (en)	2014-04-09
SMT201700110B (it)	2017-03-08
ES2615737T3 (es)	2017-06-08
WO2012163817A3 (en)	2013-03-21
CN103717742B (zh)	2018-05-22
RS55605B1 (sr)	2017-06-30
US20140093529A1 (en)	2014-04-03
JP2017012160A (ja)	2017-01-19
FI3564378T3 (fi)	2024-01-18
CN103732750A (zh)	2014-04-16
MX2013013924A (es)	2013-12-16
EP3564378A1 (en)	2019-11-06
BR112013030395A2 (pt)	2016-12-13
EA201391548A1 (ru)	2014-06-30
SI3138916T1 (sl)	2019-08-30
IL229529A0 (en)	2014-01-30
PL2714911T3 (pl)	2017-05-31
ES2968455T3 (es)	2024-05-09
KR102014502B1 (ko)	2019-08-26
IL229529B1 (en)	2023-01-01
HRP20191291T1 (hr)	2019-10-18
CA2837395A1 (en)	2012-12-06
MX346200B (es)	2017-03-10
WO2012163817A2 (en)	2012-12-06
HRP20231749T1 (hr)	2024-03-15
SI2714911T1 (sl)	2017-03-31
PT3138916T (pt)	2019-09-17
CA2837395C (en)	2021-05-18
EP3327126A1 (en)	2018-05-30
BR112013030396A2 (pt)	2016-12-13
HUE064492T2 (hu)	2024-03-28
JP5952390B2 (ja)	2016-07-13
IL229529B2 (en)	2023-05-01
DK3564378T3 (da)	2024-01-08
US10093722B2 (en)	2018-10-09
LT2714911T (lt)	2017-02-10
PL2714910T3 (pl)	2018-06-29
JP2014522238A (ja)	2014-09-04
LT3564378T (lt)	2024-01-25
US20170247421A1 (en)	2017-08-31
EP2714911B1 (en)	2016-11-30
WO2012163811A1 (en)	2012-12-06
CY1121936T1 (el)	2020-10-14
US9644024B2 (en)	2017-05-09
DK2714911T3 (en)	2017-02-27
CN103717742A (zh)	2014-04-09
CN107098977A (zh)	2017-08-29
PL3564378T3 (pl)	2024-03-11
HUE037126T2 (hu)	2018-08-28
US20140178424A1 (en)	2014-06-26
EP3138916B1 (en)	2019-06-19
US20160159867A1 (en)	2016-06-09
PT2714910T (pt)	2018-03-09
CA2837393A1 (en)	2012-12-06
LT2714910T (lt)	2018-03-12
CY1118599T1 (el)	2017-07-12
EP2714910A1 (en)	2014-04-09
SI3564378T1 (sl)	2024-02-29
WO2012163810A1 (en)	2012-12-06
HRP20180339T1 (hr)	2018-03-23
US20170362309A1 (en)	2017-12-21
ES2743442T3 (es)	2020-02-19
DK3138916T3 (da)	2019-08-26
EP4296361A3 (en)	2024-02-28
HRP20170094T1 (hr)	2017-03-24
ES2660468T3 (es)	2018-03-22
CY1119916T1 (el)	2018-06-27
JP2014516532A (ja)	2014-07-17
EP2714910B1 (en)	2018-01-10
ME02600B (me)	2017-06-20
DK2714910T3 (en)	2018-02-05
LT3138916T (lt)	2019-08-26
EP4296361A2 (en)	2023-12-27
EP3564378B1 (en)	2023-11-01
US10377816B2 (en)	2019-08-13
KR20140019848A (ko)	2014-02-17
EP3138916A1 (en)	2017-03-08
US9409974B2 (en)	2016-08-09
BR112013030395B1 (pt)	2022-11-01
SG195037A1 (en)	2013-12-30
EA030898B1 (ru)	2018-10-31
US9290565B2 (en)	2016-03-22
PT2714911T (pt)	2017-02-06
HUE030823T2 (hu)	2017-06-28
PT3564378T (pt)	2024-01-26

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HK1231412A1 (zh)	2017-12-22	免疫原性組合物
GB201003924D0 (en)	2010-04-21	Immunogenic composition
ZA201503927B (en)	2017-11-29	Immunogenic composition
SG11201404447WA (en)	2014-08-28	Immunogenic composition
PL2714911T3 (pl)	2017-05-31	Kompozycja immunogenna
IL238079A0 (en)	2015-05-31	Immunogenic preparation
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SG11201500979RA (en)	2015-07-30	Immunogenic composition
GB201223342D0 (en)	2013-02-06	Immunogenic composition
EP2609931A4 (en)	2014-06-04	IMMUNOGENIC COMPOSITION
GB201218660D0 (en)	2012-11-28	Immunogenic composition
GB201204968D0 (en)	2012-05-02	Immunogenic composition
GB201204851D0 (en)	2012-05-02	Immunogenic composition
GB201003918D0 (en)	2010-04-21	Immunogenic composition