HUE037227T2 - Recombinant HCMV and RHCMV vectors and uses thereof - Google Patents
Recombinant HCMV and RHCMV vectors and uses thereofInfo
- Publication number
- HUE037227T2 HUE037227T2 HUE14162929A HUE14162929A HUE037227T2 HU E037227 T2 HUE037227 T2 HU E037227T2 HU E14162929 A HUE14162929 A HU E14162929A HU E14162929 A HUE14162929 A HU E14162929A HU E037227 T2 HUE037227 T2 HU E037227T2
- Authority
- HU
- Hungary
- Prior art keywords
- recombinant hcmv
- rhcmv vectors
- rhcmv
- vectors
- hcmv
- Prior art date
Links
- 241000701024 Human betaherpesvirus 5 Species 0.000 title 1
- 239000013598 vector Substances 0.000 title 1
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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PCT/US2011/029930 WO2011119920A2 (en) | 2010-03-25 | 2011-03-25 | Cmv glycoproteins and recombinant vectors |
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HUE17205199A HUE050909T2 (en) | 2010-05-14 | 2011-05-16 | Recombinant hcmv and rhcmv vectors encoding a heterologous antigen isolated from a paramyxoviridae virus and uses thereof |
HUE11781407A HUE036122T2 (en) | 2010-05-14 | 2011-05-16 | Recombinant hcmv and rhcmv vectors and uses thereof |
HUE17197412A HUE049725T2 (en) | 2010-05-14 | 2011-05-16 | Recombinant hcmv and rhcmv vectors encoding a heterologous antigen isolated from hepatitis b virus and uses thereof |
HUE14162929A HUE037227T2 (en) | 2010-05-14 | 2011-05-16 | Recombinant HCMV and RHCMV vectors and uses thereof |
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HUE11781407A HUE036122T2 (en) | 2010-05-14 | 2011-05-16 | Recombinant hcmv and rhcmv vectors and uses thereof |
HUE17197412A HUE049725T2 (en) | 2010-05-14 | 2011-05-16 | Recombinant hcmv and rhcmv vectors encoding a heterologous antigen isolated from hepatitis b virus and uses thereof |
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Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102844663B (en) * | 2010-01-27 | 2016-01-06 | 俄勒冈健康科学大学 | Based on the immunogenic formulation of cytomegalovirus |
EP3187585A1 (en) * | 2010-03-25 | 2017-07-05 | Oregon Health&Science University | Cmv glycoproteins and recombinant vectors |
LT3333265T (en) * | 2010-05-14 | 2020-05-25 | Oregon Health & Science University | Recombinant hcmv and rhcmv vectors encoding a heterologous antigen isolated from hepatitis b virus and uses thereof |
EP2697248B1 (en) * | 2011-04-15 | 2020-03-11 | Nauclér, Cecilia | Genetic variant of cytomegalovirus (cmv) |
PL2691530T3 (en) | 2011-06-10 | 2019-02-28 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
CA2890061A1 (en) * | 2012-12-04 | 2014-06-12 | Merck Sharp & Dohme Corp. | Conditional replicating viral vectors |
AU2014207618A1 (en) | 2013-01-16 | 2015-08-06 | Emory University | Cas9-nucleic acid complexes and uses related thereto |
GB201301119D0 (en) * | 2013-01-22 | 2013-03-06 | Vaxxit Srl | Viral vaccines |
JP6483033B2 (en) * | 2013-03-05 | 2019-03-13 | オレゴン・ヘルス・アンド・サイエンス・ユニバーシティOregon Health & Science University | Cytomegalovirus vector capable of regulating T cell targeting |
US20140335115A1 (en) * | 2013-05-07 | 2014-11-13 | Oregon Health & Science University | Suppressors of mature t cells |
EP3063274A4 (en) * | 2013-10-29 | 2017-04-05 | The University Of Sydney | Cmv immuno-stimulatory composition |
SG11201607287XA (en) | 2014-03-01 | 2016-09-29 | Univ Texas | Recombinant isfahan viral vectors |
MA39818A (en) | 2014-03-30 | 2017-02-08 | Benevir Biopharm Inc | Exogenous tap inhibitor "armed" oncolytic viruses and therapeutic uses thereof |
CN107002048B (en) * | 2014-07-16 | 2021-07-06 | 俄勒冈健康与科学大学 | Human cytomegalovirus comprising exogenous antigen |
MA40783A (en) | 2014-10-03 | 2017-08-08 | Los Alamos Nat Security Llc | HIV VACCINES CONTAINING ONE OR MORE POPULATION EPISENSUS ANTIGENS |
GB201501523D0 (en) * | 2015-01-30 | 2015-03-18 | Univ Plymouth | Differential immune response modulation |
EP3256595A4 (en) * | 2015-02-10 | 2018-09-26 | Oregon Health & Science University | Methods and compositions useful in generating non canonical cd8+ t cell responses |
US10117911B2 (en) | 2015-05-29 | 2018-11-06 | Agenovir Corporation | Compositions and methods to treat herpes simplex virus infections |
US20160346362A1 (en) * | 2015-05-29 | 2016-12-01 | Agenovir Corporation | Methods and compositions for treating cytomegalovirus infections |
GB201514034D0 (en) * | 2015-08-08 | 2015-09-23 | Univ Plymouth | Improvements in or relating to DNA recombination |
MA43285A (en) * | 2015-11-20 | 2018-09-26 | Univ Oregon Health & Science | CMV VECTORS INCLUDING MICRORNA RECOGNITION ELEMENTS |
WO2017112797A1 (en) | 2015-12-22 | 2017-06-29 | Thomas Jefferson University | Intra-lesional cmv-based cancer vaccines |
US10611800B2 (en) | 2016-03-11 | 2020-04-07 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
CA3028827A1 (en) | 2016-06-22 | 2017-12-28 | Aeras | Recombinant cytomegalovirus vectors as vaccines for tuberculosis |
EP3475446A1 (en) * | 2016-06-27 | 2019-05-01 | Juno Therapeutics, Inc. | Method of identifying peptide epitopes, molecules that bind such epitopes and related uses |
MX2019004518A (en) | 2016-10-18 | 2019-06-17 | Univ Oregon Health & Science | Cytomegalovirus vectors eliciting t cells restricted by major histocompatibility complex e molecules. |
US11638749B2 (en) | 2017-10-17 | 2023-05-02 | International Aids Vaccine Initiative, Inc. | Tuberculosis antigen cassettes |
WO2019173783A1 (en) * | 2018-03-09 | 2019-09-12 | The Regents Of The University Of California | Cmv vectors and uses thereof |
US20210047626A1 (en) | 2018-04-24 | 2021-02-18 | Merck Sharp & Dohme Corp. | Scalable chromatography process for purification of human cytomegalovirus |
US11629172B2 (en) | 2018-12-21 | 2023-04-18 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
EP3905880A4 (en) | 2019-01-03 | 2022-10-05 | Merck Sharp & Dohme Corp. | Supplemented serum-containing culture medium for enhanced arpe-19 growth and human cytomegalovirus vaccine production |
CN114025792A (en) | 2019-03-21 | 2022-02-08 | 21C生物公司 | Vaccine against pathogenic immune-activated cells during infection |
US11077185B2 (en) | 2019-03-21 | 2021-08-03 | 21C Bio | Vaccine to pathogenic immune activation cells during infections |
US10632186B1 (en) | 2019-03-21 | 2020-04-28 | 21C Bio | Vaccine to pathogenic immune activation cells during infections |
US20220257740A1 (en) * | 2019-06-07 | 2022-08-18 | Oregon Health & Science University | Tumor-associated antigen-specific t cell responses |
TWI810589B (en) | 2020-06-21 | 2023-08-01 | 美商輝瑞股份有限公司 | Human cytomegalovirus gb polypeptide |
CN117836311A (en) * | 2021-08-31 | 2024-04-05 | 维尔生物科技公司 | Methods for generating CMV vectors |
KR20240049802A (en) | 2021-08-31 | 2024-04-17 | 비르 바이오테크놀로지, 인코포레이티드 | tuberculosis vaccine |
AU2022339765A1 (en) | 2021-08-31 | 2024-01-25 | Vir Biotechnology, Inc. | Recombinant hcmv vectors and uses thereof |
WO2023059112A1 (en) * | 2021-10-06 | 2023-04-13 | 주식회사 지앤피바이오사이언스 | Development of optimal recombinant expression construct |
WO2023133400A2 (en) * | 2022-01-07 | 2023-07-13 | Mayo Foundation For Medical Education And Research | Cytomegalovirus vectors and methods of use |
Family Cites Families (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6267965B1 (en) * | 1981-12-24 | 2001-07-31 | Virogenetics Corporation | Recombinant poxvirus—cytomegalovirus compositions and uses |
US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
US5273876A (en) | 1987-06-26 | 1993-12-28 | Syntro Corporation | Recombinant human cytomegalovirus containing foreign gene |
WO1988010311A1 (en) | 1987-06-26 | 1988-12-29 | Syntro Corporation | Recombinant human cytomegalovirus containing foreign gene and use thereof |
US5549910A (en) | 1989-03-31 | 1996-08-27 | The Regents Of The University Of California | Preparation of liposome and lipid complex compositions |
JP3218637B2 (en) | 1990-07-26 | 2001-10-15 | 大正製薬株式会社 | Stable aqueous liposome suspension |
JP2958076B2 (en) | 1990-08-27 | 1999-10-06 | 株式会社ビタミン研究所 | Multilamellar liposome for gene transfer and gene-captured multilamellar liposome preparation and method for producing the same |
EP1092775A1 (en) | 1991-07-05 | 2001-04-18 | American Cyanamid Company | Methods for identifiying non-essential genes of the human cytomegalovirus genome and for screening for inhibitors of human cytomegalovirus |
WO1995003399A2 (en) * | 1993-07-19 | 1995-02-02 | Cantab Pharmaceuticals Research Limited | Production method for preparation of disabled viruses |
WO1995030019A1 (en) | 1994-04-29 | 1995-11-09 | Pharmacia & Upjohn Company | Feline immunodeficiency virus vaccine |
US5741516A (en) | 1994-06-20 | 1998-04-21 | Inex Pharmaceuticals Corporation | Sphingosomes for enhanced drug delivery |
US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
EP0772619B2 (en) | 1994-07-15 | 2010-12-08 | The University of Iowa Research Foundation | Immunomodulatory oligonucleotides |
US6239116B1 (en) | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
US6429199B1 (en) | 1994-07-15 | 2002-08-06 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules for activating dendritic cells |
US5846806A (en) | 1994-07-29 | 1998-12-08 | American Cyanamid Company | Identification of a human cytomegalovirus gene region involved in down-regulation of MHC class I heavy chain expression |
US5795587A (en) | 1995-01-23 | 1998-08-18 | University Of Pittsburgh | Stable lipid-comprising drug delivery complexes and methods for their production |
JPH11500014A (en) * | 1995-02-21 | 1999-01-06 | キャンタブ ファーマシューティカルズ リサーチ リミティド | Viral preparations, vectors, immunogens, and vaccines |
JPH11503024A (en) | 1995-04-04 | 1999-03-23 | セル・ジェネシス・インコーポレイテッド | Transplantation of genetically modified cells with low levels of cell surface class I MHC proteins |
US5738868A (en) | 1995-07-18 | 1998-04-14 | Lipogenics Ltd. | Liposome compositions and kits therefor |
ES2237800T3 (en) | 1996-07-31 | 2005-08-01 | Ortho-Mcneil Pharmaceutical, Inc. | IDENTIFICATION OF GENES OF THE HUMAN CITOMEGALOVIRUS INVOLVED IN THE RETRO-REGULATION OF THE EXPRESSION OF HEAVY CHAINS OF CLASS I OF THE CMH. |
JP2001513776A (en) | 1997-02-28 | 2001-09-04 | ユニバーシティ オブ アイオワ リサーチ ファウンデーション | Use of nucleic acids containing unmethylated CpG dinucleotides in the treatment of LPS-related disorders |
US6406705B1 (en) | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
AU7690898A (en) | 1997-05-20 | 1998-12-11 | Ottawa Civic Hospital Loeb Research Institute | Vectors and methods for immunization or therapeutic protocols |
US20030138454A1 (en) * | 1997-06-09 | 2003-07-24 | Oxxon Pharmaccines, Ltd. | Vaccination method |
DE19733364A1 (en) * | 1997-08-01 | 1999-02-04 | Koszinowski Ulrich H Prof | Method of cloning a large virus genome |
WO1999007869A1 (en) * | 1997-08-05 | 1999-02-18 | University Of Florida | Live recombinant vaccine comprising inefficiently or non-replicating virus |
JP2002510644A (en) | 1998-04-03 | 2002-04-09 | ユニバーシティ オブ アイオワ リサーチ ファウンデーション | Methods and products for immune system stimulation using immunotherapeutic oligonucleotides and cytokines |
US20020102536A1 (en) * | 1999-11-19 | 2002-08-01 | Xenova Research Limited | Preparation of human or animal herpesviruses |
US7204990B1 (en) * | 2000-11-28 | 2007-04-17 | Medimmune Vaccines, Inc. | Attenuation of cytomegalovirus virulence |
CA2437201C (en) * | 2001-02-02 | 2008-11-18 | Chemocentryx, Inc. | Methods and compositions useful for stimulating an immune response |
AU2002247733B2 (en) | 2001-02-21 | 2007-12-13 | The Wistar Institute Of Anatomy And Biology | Recombinant vector containing infectious human cytomegalovirus genome with preserved wild-type characteristics of clinical isolates |
GB0122232D0 (en) * | 2001-09-14 | 2001-11-07 | Medical Res Council | Gene expression |
AU2002362368B2 (en) * | 2001-09-20 | 2006-09-21 | Glaxo Group Limited | HIV-gag codon-optimised DNA vaccines |
SG2013034475A (en) * | 2001-11-21 | 2016-10-28 | Univ Pennsylvania | Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use |
US20030118568A1 (en) | 2001-12-18 | 2003-06-26 | Board Of Trustees Of The University Of Arkansas | Viral stealth technology to prevent T cell-mediated rejection of xenografts |
CN100471957C (en) * | 2002-04-30 | 2009-03-25 | 艾维亚医药/生物技术有限公司 | Adenovirus vectors for immunotherapy |
CA2484669A1 (en) * | 2002-05-08 | 2003-11-20 | Akzo Nobel N.V. | Brachyspira hyodysenteriae vaccine |
DE10232322A1 (en) | 2002-07-16 | 2004-07-29 | Hahn, Gabriele, Dr. | Virally encoded CxC determine the tissue tropism of HCMV |
WO2005012545A2 (en) * | 2003-07-25 | 2005-02-10 | The Regents Of The University Of California | Cytomegalovirus gene function and methods for developing antivirals, anti-cmv vaccines, and cmv-based vectors |
EP1766096B1 (en) | 2004-05-25 | 2013-01-02 | Oregon Health and Science University | Hiv vaccination usingand hcmv-based vaccine vectors |
EP1602676A1 (en) | 2004-06-01 | 2005-12-07 | SOLVAY (Société Anonyme) | Catalytic compositions |
EP1799255A4 (en) * | 2004-06-25 | 2008-10-01 | Medimmune Vaccines Inc | Recombinant human cytomegalovirus and vaccines comprising heterologous antigens |
US8668564B2 (en) | 2005-01-24 | 2014-03-11 | Solution Champion Limited | Jackpot method and system |
EP1888622A1 (en) * | 2005-05-23 | 2008-02-20 | Oxxon Therapeutics Ltd. | Compositions for inducing an immune response against hepatitis b |
CA2620495A1 (en) * | 2005-08-31 | 2007-03-08 | Genvec, Inc. | Adenoviral vector-based malaria vaccines |
JP5349049B2 (en) | 2005-10-17 | 2013-11-20 | メディミューン,エルエルシー | Multiplasmid system for influenza virus production |
WO2008112146A2 (en) | 2007-03-07 | 2008-09-18 | The Trustees Of The University Of Pennsylvania | 2d partially parallel imaging with k-space surrounding neighbors based data reconstruction |
AU2008287195A1 (en) | 2007-07-06 | 2009-02-19 | Emergent Product Development Seattle, Llc | Binding peptides having a C-terminally disposed specific binding domain |
PT2215117E (en) | 2007-10-30 | 2015-04-01 | Genentech Inc | Antibody purification by cation exchange chromatography |
JP2012519484A (en) | 2009-03-06 | 2012-08-30 | マウント・シナイ・スクール・オヴ・メディシン | Live attenuated influenza virus vaccine containing a microRNA response element |
ES2786039T3 (en) | 2009-04-30 | 2020-10-08 | Ospedale San Raffaele Srl | Gene vector |
BR112012015523A2 (en) | 2009-12-23 | 2017-04-18 | 4-Antibody Ag | human cytomegalovirus binding members, composition containing them, method of treatment, antibody molecules, production method, nucleic acid molecular, host cell, and hcmv neutralization method. |
CN102844663B (en) | 2010-01-27 | 2016-01-06 | 俄勒冈健康科学大学 | Based on the immunogenic formulation of cytomegalovirus |
EP3187585A1 (en) * | 2010-03-25 | 2017-07-05 | Oregon Health&Science University | Cmv glycoproteins and recombinant vectors |
CA2798214C (en) | 2010-05-05 | 2021-10-19 | Christian Thirion | Vaccine against beta-herpesvirus infection and use thereof |
LT3333265T (en) | 2010-05-14 | 2020-05-25 | Oregon Health & Science University | Recombinant hcmv and rhcmv vectors encoding a heterologous antigen isolated from hepatitis b virus and uses thereof |
PL2691530T3 (en) | 2011-06-10 | 2019-02-28 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
US20140227708A1 (en) | 2011-09-16 | 2014-08-14 | Oregon Health & Science University | Methods and kits used in identifying microrna targets |
US20130156808A1 (en) | 2011-11-22 | 2013-06-20 | Stipan Jonjic | Vaccine comprising beta-herpesvirus |
JP6483033B2 (en) | 2013-03-05 | 2019-03-13 | オレゴン・ヘルス・アンド・サイエンス・ユニバーシティOregon Health & Science University | Cytomegalovirus vector capable of regulating T cell targeting |
CN107002048B (en) | 2014-07-16 | 2021-07-06 | 俄勒冈健康与科学大学 | Human cytomegalovirus comprising exogenous antigen |
EP3048114A1 (en) * | 2015-01-22 | 2016-07-27 | Novartis AG | Cytomegalovirus antigens and uses thereof |
EP3256595A4 (en) | 2015-02-10 | 2018-09-26 | Oregon Health & Science University | Methods and compositions useful in generating non canonical cd8+ t cell responses |
MA43285A (en) | 2015-11-20 | 2018-09-26 | Univ Oregon Health & Science | CMV VECTORS INCLUDING MICRORNA RECOGNITION ELEMENTS |
CA3028827A1 (en) | 2016-06-22 | 2017-12-28 | Aeras | Recombinant cytomegalovirus vectors as vaccines for tuberculosis |
EP3475446A1 (en) | 2016-06-27 | 2019-05-01 | Juno Therapeutics, Inc. | Method of identifying peptide epitopes, molecules that bind such epitopes and related uses |
MX2019004518A (en) | 2016-10-18 | 2019-06-17 | Univ Oregon Health & Science | Cytomegalovirus vectors eliciting t cells restricted by major histocompatibility complex e molecules. |
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